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The map label for this gene is pgcA [H]

Identifier: 152977212

GI number: 152977212

Start: 3597873

End: 3599597

Strand: Reverse

Name: pgcA [H]

Synonym: Bcer98_3530

Alternate gene names: 152977212

Gene position: 3599597-3597873 (Counterclockwise)

Preceding gene: 152977214

Following gene: 152977211

Centisome position: 88.07

GC content: 36.93

Gene sequence:

>1725_bases
ATGGAGTGGAAAAAAGAATATAGCCGCTGGCTTTCTTATGCAAACTTAGATGCAGAATTAAAACAGCAGCTAGAAGATAT
GAAACAAGATGAGAAGAAAATAGAAGATAGCTTCTATAAAAATTTAGAATTCGGTACCGGTGGTATGCGCGGTGAACTGG
GGGCTGGTACGAATCGTTTAAATGTATATACTGTTCGAAAAGCGACAAAAGGACTTGCACACTTTATTGAGAGTTTAGGT
GAAGAAGCGAAGAAACGCGGCGTAGTTGTTGCGTATGATTCTCGTCATAAATCGCCCGAATTTGCAATGGAAGTAGCTGC
AACATTAGGGGCGCATGGCATTACAACATATGTATTCGAAAGTTTACGTCCAACACCAGTACTTTCTTTCGCAGTACGTC
ATTTACATACAATAAGTGGAATCGTTCTTACAGCAAGTCATAATCCACCCGAATATAATGGATATAAAGTATACGGTGAA
GATGGTGGACAATTGCCACCAAAAGAAGCAGATGAGTTAATTCGTTATGTAAATCAAGTGGAAGATGAATTAACGGTAGA
AGTTGCGAATGTAGAGCAATTAAAAGCGGATGGATTATTACATATCATCGGGACAGAAGTAGATGAGGCATATGTAGAGC
AGTTAAAAACAGTTATCATAAATAAAGAAATGGTTGAGAAAGTTGGGAAAGATTTAAAAATCGTCTTTACACCACTGCAT
GGAACATCTAATATTCCAGTACGCCAAGGCTTAGAAGCAGTTGGATTTACAGATGTAACAGTCGTAAAAGAGCAGGAGTT
ACCAGATCCAAACTTTTCTACGGTTAAATCACCAAATCCAGAGGAACATGCTGCATTTGAACTGGCAATTCGTGATGGTG
AAAAAGTAGGAGCGGACGTATTAATTGCAACGGATCCAGACGCGGATCGCCTAGGTGTAGCGGTTCGTAATCATAACGGA
GAATTCCAAGTATTAACAGGGAACCAAACAGGCGCATTAATGCTTGAGTATTTATTATCACAAAAGGAACAAAATGGTAC
CCTTCCAAAGAACGGTGTTGTACTAAAAACAATCGTAACGTCTGAAATTGGCCGTACAATTGCAAAAGCATATGGCTTAG
ATACAGTTGATACATTAACTGGATTTAAGTTTATTGGTGAGAAAATTAAACAATATGAAGAAAGCGGACAATATGAGTTC
CAATTTGGATATGAAGAAAGTTATGGATATTTAATTCGTCCATTCTGTCGTGATAAAGATGCAGTTCAGTCTGTATTATT
TGCATGTGAAGTAGCAGCATACTATAAATCACAAGGGAAAACATTGTATGATGGATTACTAGAAATATTTGAAAAGTATG
GTTTCTTCCGCGAAGATCTTGTGTCTTTAACGTTAAAAGGAAAAGATGGAGCGGAGAAAATTCAAGAAATGATGACAGCA
TTCCGTGAAAATCCACCAAAAGAAGTGGCTGGTTTAACAGTAAAAACAGTAGAAGATTATAAGGCAAGTACGATTACATC
TCTAATAGATGGAAGTCAAGAAGAAATTCAATTACCAAAATCTAATGTGCTAAAATATCAACTAACAGATGGTTCTTGGT
TCTGTTTACGTCCGTCCGGCACAGAGCCAAAGATTAAGTTTTATTTTGGTGTGAAAGCTGATTCTTTACAAAATAGTGAA
CAAAAGTTACTTACTATTAAAGAAGATGTTATGAATCGTTTATAA

Upstream 100 bases:

>100_bases
AAATTATAAAAGTAAAATCCTGTTAGATTTTAAAATGTATTGAGATAATTGCTGTTTTTTTCATATAATAAAGTTATGAC
AAGCGAGAGGAGATAAGAGG

Downstream 100 bases:

>100_bases
TGAAACCGATCCATGATGTTTATTAAAGGAGAGCAAAGGGGAGAGTGACCTCCTCTTTTCTTGTATATAAAAATGAGATA
TGTAAGCAGAATGGATATGA

Product: phosphoglucomutase/phosphomannomutase alpha/beta/subunit

Products: NA

Alternate protein names: PGM; Alpha-phosphoglucomutase; Glucose phosphomutase [H]

Number of amino acids: Translated: 574; Mature: 574

Protein sequence:

>574_residues
MEWKKEYSRWLSYANLDAELKQQLEDMKQDEKKIEDSFYKNLEFGTGGMRGELGAGTNRLNVYTVRKATKGLAHFIESLG
EEAKKRGVVVAYDSRHKSPEFAMEVAATLGAHGITTYVFESLRPTPVLSFAVRHLHTISGIVLTASHNPPEYNGYKVYGE
DGGQLPPKEADELIRYVNQVEDELTVEVANVEQLKADGLLHIIGTEVDEAYVEQLKTVIINKEMVEKVGKDLKIVFTPLH
GTSNIPVRQGLEAVGFTDVTVVKEQELPDPNFSTVKSPNPEEHAAFELAIRDGEKVGADVLIATDPDADRLGVAVRNHNG
EFQVLTGNQTGALMLEYLLSQKEQNGTLPKNGVVLKTIVTSEIGRTIAKAYGLDTVDTLTGFKFIGEKIKQYEESGQYEF
QFGYEESYGYLIRPFCRDKDAVQSVLFACEVAAYYKSQGKTLYDGLLEIFEKYGFFREDLVSLTLKGKDGAEKIQEMMTA
FRENPPKEVAGLTVKTVEDYKASTITSLIDGSQEEIQLPKSNVLKYQLTDGSWFCLRPSGTEPKIKFYFGVKADSLQNSE
QKLLTIKEDVMNRL

Sequences:

>Translated_574_residues
MEWKKEYSRWLSYANLDAELKQQLEDMKQDEKKIEDSFYKNLEFGTGGMRGELGAGTNRLNVYTVRKATKGLAHFIESLG
EEAKKRGVVVAYDSRHKSPEFAMEVAATLGAHGITTYVFESLRPTPVLSFAVRHLHTISGIVLTASHNPPEYNGYKVYGE
DGGQLPPKEADELIRYVNQVEDELTVEVANVEQLKADGLLHIIGTEVDEAYVEQLKTVIINKEMVEKVGKDLKIVFTPLH
GTSNIPVRQGLEAVGFTDVTVVKEQELPDPNFSTVKSPNPEEHAAFELAIRDGEKVGADVLIATDPDADRLGVAVRNHNG
EFQVLTGNQTGALMLEYLLSQKEQNGTLPKNGVVLKTIVTSEIGRTIAKAYGLDTVDTLTGFKFIGEKIKQYEESGQYEF
QFGYEESYGYLIRPFCRDKDAVQSVLFACEVAAYYKSQGKTLYDGLLEIFEKYGFFREDLVSLTLKGKDGAEKIQEMMTA
FRENPPKEVAGLTVKTVEDYKASTITSLIDGSQEEIQLPKSNVLKYQLTDGSWFCLRPSGTEPKIKFYFGVKADSLQNSE
QKLLTIKEDVMNRL
>Mature_574_residues
MEWKKEYSRWLSYANLDAELKQQLEDMKQDEKKIEDSFYKNLEFGTGGMRGELGAGTNRLNVYTVRKATKGLAHFIESLG
EEAKKRGVVVAYDSRHKSPEFAMEVAATLGAHGITTYVFESLRPTPVLSFAVRHLHTISGIVLTASHNPPEYNGYKVYGE
DGGQLPPKEADELIRYVNQVEDELTVEVANVEQLKADGLLHIIGTEVDEAYVEQLKTVIINKEMVEKVGKDLKIVFTPLH
GTSNIPVRQGLEAVGFTDVTVVKEQELPDPNFSTVKSPNPEEHAAFELAIRDGEKVGADVLIATDPDADRLGVAVRNHNG
EFQVLTGNQTGALMLEYLLSQKEQNGTLPKNGVVLKTIVTSEIGRTIAKAYGLDTVDTLTGFKFIGEKIKQYEESGQYEF
QFGYEESYGYLIRPFCRDKDAVQSVLFACEVAAYYKSQGKTLYDGLLEIFEKYGFFREDLVSLTLKGKDGAEKIQEMMTA
FRENPPKEVAGLTVKTVEDYKASTITSLIDGSQEEIQLPKSNVLKYQLTDGSWFCLRPSGTEPKIKFYFGVKADSLQNSE
QKLLTIKEDVMNRL

Specific function: Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI31377548, Length=565, Percent_Identity=33.9823008849557, Blast_Score=282, Evalue=6e-76,
Organism=Homo sapiens, GI63055049, Length=565, Percent_Identity=31.3274336283186, Blast_Score=280, Evalue=4e-75,
Organism=Caenorhabditis elegans, GI71993870, Length=556, Percent_Identity=31.8345323741007, Blast_Score=246, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI71993878, Length=343, Percent_Identity=31.4868804664723, Blast_Score=154, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6323934, Length=590, Percent_Identity=31.864406779661, Blast_Score=206, Evalue=7e-54,
Organism=Drosophila melanogaster, GI20129809, Length=560, Percent_Identity=28.0357142857143, Blast_Score=221, Evalue=9e-58,
Organism=Drosophila melanogaster, GI24651977, Length=461, Percent_Identity=29.2841648590022, Blast_Score=209, Evalue=6e-54,
Organism=Drosophila melanogaster, GI24653722, Length=581, Percent_Identity=27.5387263339071, Blast_Score=207, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 64180; Mature: 64180

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWKKEYSRWLSYANLDAELKQQLEDMKQDEKKIEDSFYKNLEFGTGGMRGELGAGTNRL
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
NVYTVRKATKGLAHFIESLGEEAKKRGVVVAYDSRHKSPEFAMEVAATLGAHGITTYVFE
EEEEEHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHH
SLRPTPVLSFAVRHLHTISGIVLTASHNPPEYNGYKVYGEDGGQLPPKEADELIRYVNQV
HCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHH
EDELTVEVANVEQLKADGLLHIIGTEVDEAYVEQLKTVIINKEMVEKVGKDLKIVFTPLH
HHHHEEEEECHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCHHHHHHCCCCEEEEEEECC
GTSNIPVRQGLEAVGFTDVTVVKEQELPDPNFSTVKSPNPEEHAAFELAIRDGEKVGADV
CCCCCCHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHCEEEEEEECCCCCCCEE
LIATDPDADRLGVAVRNHNGEFQVLTGNQTGALMLEYLLSQKEQNGTLPKNGVVLKTIVT
EEEECCCCHHEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEEEEHHHH
SEIGRTIAKAYGLDTVDTLTGFKFIGEKIKQYEESGQYEFQFGYEESYGYLIRPFCRDKD
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEHHCCCHH
AVQSVLFACEVAAYYKSQGKTLYDGLLEIFEKYGFFREDLVSLTLKGKDGAEKIQEMMTA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHEEEEECCCCHHHHHHHHHHH
FRENPPKEVAGLTVKTVEDYKASTITSLIDGSQEEIQLPKSNVLKYQLTDGSWFCLRPSG
HHCCCCHHHHCCEEEEHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEECCCCEEEECCCC
TEPKIKFYFGVKADSLQNSEQKLLTIKEDVMNRL
CCCEEEEEEECCHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEWKKEYSRWLSYANLDAELKQQLEDMKQDEKKIEDSFYKNLEFGTGGMRGELGAGTNRL
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
NVYTVRKATKGLAHFIESLGEEAKKRGVVVAYDSRHKSPEFAMEVAATLGAHGITTYVFE
EEEEEHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHH
SLRPTPVLSFAVRHLHTISGIVLTASHNPPEYNGYKVYGEDGGQLPPKEADELIRYVNQV
HCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHH
EDELTVEVANVEQLKADGLLHIIGTEVDEAYVEQLKTVIINKEMVEKVGKDLKIVFTPLH
HHHHEEEEECHHHHHHCCEEEEECCCHHHHHHHHHHHHHHCHHHHHHCCCCEEEEEEECC
GTSNIPVRQGLEAVGFTDVTVVKEQELPDPNFSTVKSPNPEEHAAFELAIRDGEKVGADV
CCCCCCHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHCEEEEEEECCCCCCCEE
LIATDPDADRLGVAVRNHNGEFQVLTGNQTGALMLEYLLSQKEQNGTLPKNGVVLKTIVT
EEEECCCCHHEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEEEEHHHH
SEIGRTIAKAYGLDTVDTLTGFKFIGEKIKQYEESGQYEFQFGYEESYGYLIRPFCRDKD
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEHHCCCHH
AVQSVLFACEVAAYYKSQGKTLYDGLLEIFEKYGFFREDLVSLTLKGKDGAEKIQEMMTA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHEEEEECCCCHHHHHHHHHHH
FRENPPKEVAGLTVKTVEDYKASTITSLIDGSQEEIQLPKSNVLKYQLTDGSWFCLRPSG
HHCCCCHHHHCCEEEEHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEECCCCEEEECCCC
TEPKIKFYFGVKADSLQNSEQKLLTIKEDVMNRL
CCCEEEEEEECCHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 2127799 [H]