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The map label for this gene is hemN [H]

Identifier: 152976747

GI number: 152976747

Start: 3090123

End: 3091259

Strand: Reverse

Name: hemN [H]

Synonym: Bcer98_3043

Alternate gene names: 152976747

Gene position: 3091259-3090123 (Counterclockwise)

Preceding gene: 152976748

Following gene: 152976746

Centisome position: 75.64

GC content: 36.59

Gene sequence:

>1137_bases
ATGCAAGCTGCATATATCCATATTCCATTTTGTCAGCATATTTGTCACTATTGTGATTTTAATAAAGTATTTATTGAGCG
TCAGCCTGTTGATCAATATTTAGAGTATTTAGAAAAGGAAATCGTGAATACGGTGCAAAAGGCTCCTTTTAAGCAGATGA
AAACGATATTTGTAGGAGGAGGGACACCGACAGCGTTAAATATGAAGCAGACAAAAAAATTGCTCGATATTATAAATCGT
CGTTTACGACCGTTTGCTCCAAACTGTGAAGTAACGTTTGAAGCGAATCCTGGAGATTTGCCAAAAGAAAAGTTAAACCT
TCTATTAGAAGGAGGCGTGAACCGAATTAGTTTTGGTGTGCAAACATTTCGCGATGAACTATTGAAAAAAATCGGGCGTA
AGCATACGAGAGAAGATGCGTTTGTTGCCATTCGTGAAGCGCAGGAAGTAGGATTTACAAATATTAATATTGATTTAATT
TATGCATTGCCAGGGCAAACAATTGAAGATGTAAAAGAAACGTTAAATATCGCTTTTACACTTGGAGTGCAGCATTTCTC
GGCGTATTCTTTAATTGTTGAACCGAAAACAGTATTTTACAATTTAATGAATAAAGGAAAATTACGGCTACCAGGTGAAG
AACATGAAGCAAAAATGTACGAGATGGTCATGGATGAAATGGAGAAACATGGGTATCATCAGTATGAAATTAGTAATTTT
GCAAAAGAAGGTCATGAAAGTAGACATAATCTCACATACTGGAATAATGAAGCTTACTATGGGTTCGGCGCTGGGGCACA
TAGTTATATAAATGGTGAACGAATTCAAAATGTTGGTCCGTTGAAACAATATTTTGCTAAAATCGACGAAACAGGGTTCC
CTTATCTAGATGTTCATCAAGTAACGGAAAAAGAGAGAATGGAAGAAGAATTGTTCTTAGGACTTCGAAAAACAAAAGGC
GTTTTAAAAAAAGCATTCCAGCAGAAATTTGGGGTGAAGATGGAGGACGTCTTTGCGAATCAATTGGCCCACAATAAAGC
ACATGGATTACTTGAGGAGAAGGATGGTCATGTTTGTTTGACAAGAACAGGGAAGTTACTAGGAAATGAAGTGTTTCAAT
CGTTCTTAGTGGATTAA

Upstream 100 bases:

>100_bases
GGGGGAAAATGCGAATGAAACAAATTCGTGATGGGTTAGAGAAGTAAAGAACCTCCGAAACGTGGAGGTTCTCTTTTTAG
AAAGGTAGGAGTAAAATTTG

Downstream 100 bases:

>100_bases
CGAAATTATTTCTGTGGAAAAAGTTTCACGAATTCGGGACGTTTCCGTTGACAATTGAATGTCAATTTTGGTAAGTTAGT
AATAGATTTAGCACTCGGGG

Product: coproporphyrinogen III oxidase

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MQAAYIHIPFCQHICHYCDFNKVFIERQPVDQYLEYLEKEIVNTVQKAPFKQMKTIFVGGGTPTALNMKQTKKLLDIINR
RLRPFAPNCEVTFEANPGDLPKEKLNLLLEGGVNRISFGVQTFRDELLKKIGRKHTREDAFVAIREAQEVGFTNINIDLI
YALPGQTIEDVKETLNIAFTLGVQHFSAYSLIVEPKTVFYNLMNKGKLRLPGEEHEAKMYEMVMDEMEKHGYHQYEISNF
AKEGHESRHNLTYWNNEAYYGFGAGAHSYINGERIQNVGPLKQYFAKIDETGFPYLDVHQVTEKERMEEELFLGLRKTKG
VLKKAFQQKFGVKMEDVFANQLAHNKAHGLLEEKDGHVCLTRTGKLLGNEVFQSFLVD

Sequences:

>Translated_378_residues
MQAAYIHIPFCQHICHYCDFNKVFIERQPVDQYLEYLEKEIVNTVQKAPFKQMKTIFVGGGTPTALNMKQTKKLLDIINR
RLRPFAPNCEVTFEANPGDLPKEKLNLLLEGGVNRISFGVQTFRDELLKKIGRKHTREDAFVAIREAQEVGFTNINIDLI
YALPGQTIEDVKETLNIAFTLGVQHFSAYSLIVEPKTVFYNLMNKGKLRLPGEEHEAKMYEMVMDEMEKHGYHQYEISNF
AKEGHESRHNLTYWNNEAYYGFGAGAHSYINGERIQNVGPLKQYFAKIDETGFPYLDVHQVTEKERMEEELFLGLRKTKG
VLKKAFQQKFGVKMEDVFANQLAHNKAHGLLEEKDGHVCLTRTGKLLGNEVFQSFLVD
>Mature_378_residues
MQAAYIHIPFCQHICHYCDFNKVFIERQPVDQYLEYLEKEIVNTVQKAPFKQMKTIFVGGGTPTALNMKQTKKLLDIINR
RLRPFAPNCEVTFEANPGDLPKEKLNLLLEGGVNRISFGVQTFRDELLKKIGRKHTREDAFVAIREAQEVGFTNINIDLI
YALPGQTIEDVKETLNIAFTLGVQHFSAYSLIVEPKTVFYNLMNKGKLRLPGEEHEAKMYEMVMDEMEKHGYHQYEISNF
AKEGHESRHNLTYWNNEAYYGFGAGAHSYINGERIQNVGPLKQYFAKIDETGFPYLDVHQVTEKERMEEELFLGLRKTKG
VLKKAFQQKFGVKMEDVFANQLAHNKAHGLLEEKDGHVCLTRTGKLLGNEVFQSFLVD

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX [H]

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=265, Percent_Identity=32.8301886792453, Blast_Score=165, Evalue=6e-41,
Organism=Escherichia coli, GI1789325, Length=376, Percent_Identity=34.5744680851064, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI87082341, Length=389, Percent_Identity=28.0205655526992, Blast_Score=157, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 43552; Mature: 43552

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAAYIHIPFCQHICHYCDFNKVFIERQPVDQYLEYLEKEIVNTVQKAPFKQMKTIFVGG
CCCEEEECHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCHHHEEEEEEEC
GTPTALNMKQTKKLLDIINRRLRPFAPNCEVTFEANPGDLPKEKLNLLLEGGVNRISFGV
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCHHHHHHH
QTFRDELLKKIGRKHTREDAFVAIREAQEVGFTNINIDLIYALPGQTIEDVKETLNIAFT
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEECCEEEEEECCCCHHHHHHHHHHHHHE
LGVQHFSAYSLIVEPKTVFYNLMNKGKLRLPGEEHEAKMYEMVMDEMEKHGYHQYEISNF
ECHHHHCEEEEEECHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
AKEGHESRHNLTYWNNEAYYGFGAGAHSYINGERIQNVGPLKQYFAKIDETGFPYLDVHQ
HHHCCCCCCCCEEECCCEEEEECCCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCEEHHHH
VTEKERMEEELFLGLRKTKGVLKKAFQQKFGVKMEDVFANQLAHNKAHGLLEEKDGHVCL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCEEE
TRTGKLLGNEVFQSFLVD
ECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MQAAYIHIPFCQHICHYCDFNKVFIERQPVDQYLEYLEKEIVNTVQKAPFKQMKTIFVGG
CCCEEEECHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCHHHEEEEEEEC
GTPTALNMKQTKKLLDIINRRLRPFAPNCEVTFEANPGDLPKEKLNLLLEGGVNRISFGV
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCHHHHHHH
QTFRDELLKKIGRKHTREDAFVAIREAQEVGFTNINIDLIYALPGQTIEDVKETLNIAFT
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEECCEEEEEECCCCHHHHHHHHHHHHHE
LGVQHFSAYSLIVEPKTVFYNLMNKGKLRLPGEEHEAKMYEMVMDEMEKHGYHQYEISNF
ECHHHHCEEEEEECHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
AKEGHESRHNLTYWNNEAYYGFGAGAHSYINGERIQNVGPLKQYFAKIDETGFPYLDVHQ
HHHCCCCCCCCEEECCCEEEEECCCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCEEHHHH
VTEKERMEEELFLGLRKTKGVLKKAFQQKFGVKMEDVFANQLAHNKAHGLLEEKDGHVCL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCEEE
TRTGKLLGNEVFQSFLVD
ECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8757728; 8969508; 9384377; 1339421 [H]