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The map label for this gene is hrcA

Identifier: 152976746

GI number: 152976746

Start: 3088961

End: 3089992

Strand: Reverse

Name: hrcA

Synonym: Bcer98_3042

Alternate gene names: 152976746

Gene position: 3089992-3088961 (Counterclockwise)

Preceding gene: 152976747

Following gene: 152976745

Centisome position: 75.6

GC content: 35.76

Gene sequence:

>1032_bases
ATGCTTACGGAACGTCAGCTCTTAATTTTACAAACAATCATTGATGATTTTATCGGATCAGCACAGCCTGTTGGATCAAG
AACGTTAGCTAAAAAAGATGAAATTACATTTAGTTCGGCTACCATTCGAAACGAGATGGCCGATTTAGAAGAACTAGGGT
TTATTGAAAAAACACATAGTTCTTCAGGACGTATTCCTTCAGAAAAAGGATACAGATTTTATGTGGATCATCTATTAGCG
CCACAACGCTTGTCCGCTGAGGAAATTGTACAAATTAAGGATTTATTTGCTGAAAGAATTTTTGAAGCAGAAAAGGTTGC
ACAGCAATCAGCTCAAATTTTGTCCGAACTCACAAATTATACAGCAATCGTTCTTGGGCCGAAATTGAGTACAAATAAAC
TCAAAAATGTACAAATTATTCCGCTGGGCCGAAAGACAGCAGTCGCAATTATTGTAACTGATACAGGGCATGTACAAAGC
AAGACGATTACCGTTCCGGAATCTGTTGATTTATCAGATTTAGAAAAAATGGTTAATATTTTAAATGAAAAACTATTTGG
TGTACCTATGGTAGAATTACACAATAAAATTGTAAAAGAAGTTGTGACAGTTCTTCATAAGTATGTCCATAACTATGATA
GTGCAATGAAAATATTAGACGGTACATTTCAAGTGCCTTTATCGGAAAAGATATACTTTGGGGGAAAAGCTAATATGCTT
GCTCAACCGGAGTTCCATGATATTCAAAAGGTGCGTTCTTTGTTAGAAATGATCGATAACGAAGCTGAATTTTACGATAT
TTTACGTAAGAAACAAGTAGGAATTCAAGTGAACATTGGTCGCGAAAATTCCTCAATGGCAATGGAAGATTGCAGCTTGA
TTTCTGCGACGTATTCTGTTGGAGAAGAACAGCTTGGAACAATTGCAATATTAGGTCCGACGAGAATGCATTATGCCCGA
GTTATTACCCTTTTACAATTATTCACAAAACACTTTACAGAGGGATTAAATGGGCTGTATAAATCAAAATAA

Upstream 100 bases:

>100_bases
AATTCGGGACGTTTCCGTTGACAATTGAATGTCAATTTTGGTAAGTTAGTAATAGATTTAGCACTCGGGGATAAAGAGTG
CTAACAGAGGTGATGATGAG

Downstream 100 bases:

>100_bases
TAAATTCGCTCGAGTAATGAAAGAAAATCATTGCTGGTGGGTAACATAAATATATGCTTGGGTGCTCATGCTCAGTGTGA
GCACTTGAACACTTTTAAGG

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDEITFSSATIRNEMADLEELGFIEKTHSSSGRIPSEKGYRFYVDHLLA
PQRLSAEEIVQIKDLFAERIFEAEKVAQQSAQILSELTNYTAIVLGPKLSTNKLKNVQIIPLGRKTAVAIIVTDTGHVQS
KTITVPESVDLSDLEKMVNILNEKLFGVPMVELHNKIVKEVVTVLHKYVHNYDSAMKILDGTFQVPLSEKIYFGGKANML
AQPEFHDIQKVRSLLEMIDNEAEFYDILRKKQVGIQVNIGRENSSMAMEDCSLISATYSVGEEQLGTIAILGPTRMHYAR
VITLLQLFTKHFTEGLNGLYKSK

Sequences:

>Translated_343_residues
MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDEITFSSATIRNEMADLEELGFIEKTHSSSGRIPSEKGYRFYVDHLLA
PQRLSAEEIVQIKDLFAERIFEAEKVAQQSAQILSELTNYTAIVLGPKLSTNKLKNVQIIPLGRKTAVAIIVTDTGHVQS
KTITVPESVDLSDLEKMVNILNEKLFGVPMVELHNKIVKEVVTVLHKYVHNYDSAMKILDGTFQVPLSEKIYFGGKANML
AQPEFHDIQKVRSLLEMIDNEAEFYDILRKKQVGIQVNIGRENSSMAMEDCSLISATYSVGEEQLGTIAILGPTRMHYAR
VITLLQLFTKHFTEGLNGLYKSK
>Mature_343_residues
MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDEITFSSATIRNEMADLEELGFIEKTHSSSGRIPSEKGYRFYVDHLLA
PQRLSAEEIVQIKDLFAERIFEAEKVAQQSAQILSELTNYTAIVLGPKLSTNKLKNVQIIPLGRKTAVAIIVTDTGHVQS
KTITVPESVDLSDLEKMVNILNEKLFGVPMVELHNKIVKEVVTVLHKYVHNYDSAMKILDGTFQVPLSEKIYFGGKANML
AQPEFHDIQKVRSLLEMIDNEAEFYDILRKKQVGIQVNIGRENSSMAMEDCSLISATYSVGEEQLGTIAILGPTRMHYAR
VITLLQLFTKHFTEGLNGLYKSK

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_BACCN (A7GT10)

Other databases:

- EMBL:   CP000764
- RefSeq:   YP_001376263.1
- ProteinModelPortal:   A7GT10
- SMR:   A7GT10
- STRING:   A7GT10
- EnsemblBacteria:   EBBACT00000038967
- GeneID:   5347012
- GenomeReviews:   CP000764_GR
- KEGG:   bcy:Bcer98_3042
- eggNOG:   COG1420
- GeneTree:   EBGT00050000002539
- HOGENOM:   HBG729878
- OMA:   LEQPHTS
- ProtClustDB:   PRK00082
- BioCyc:   BCER315749:BCER98_3042-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00081
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF01628 HrcA

EC number: NA

Molecular weight: Translated: 38486; Mature: 38486

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDEITFSSATIRNEMADLEELGFIEKTHS
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEHHHHHHHHHHHHHHCCCHHHCCC
SSGRIPSEKGYRFYVDHLLAPQRLSAEEIVQIKDLFAERIFEAEKVAQQSAQILSELTNY
CCCCCCCCCCCEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TAIVLGPKLSTNKLKNVQIIPLGRKTAVAIIVTDTGHVQSKTITVPESVDLSDLEKMVNI
EEEEECCCCCCCCCCCEEEEECCCCEEEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHH
LNEKLFGVPMVELHNKIVKEVVTVLHKYVHNYDSAMKILDGTFQVPLSEKIYFGGKANML
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEECCCCCCC
AQPEFHDIQKVRSLLEMIDNEAEFYDILRKKQVGIQVNIGRENSSMAMEDCSLISATYSV
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHC
GEEQLGTIAILGPTRMHYARVITLLQLFTKHFTEGLNGLYKSK
CHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDEITFSSATIRNEMADLEELGFIEKTHS
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEHHHHHHHHHHHHHHCCCHHHCCC
SSGRIPSEKGYRFYVDHLLAPQRLSAEEIVQIKDLFAERIFEAEKVAQQSAQILSELTNY
CCCCCCCCCCCEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TAIVLGPKLSTNKLKNVQIIPLGRKTAVAIIVTDTGHVQSKTITVPESVDLSDLEKMVNI
EEEEECCCCCCCCCCCEEEEECCCCEEEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHH
LNEKLFGVPMVELHNKIVKEVVTVLHKYVHNYDSAMKILDGTFQVPLSEKIYFGGKANML
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEECCCCCCC
AQPEFHDIQKVRSLLEMIDNEAEFYDILRKKQVGIQVNIGRENSSMAMEDCSLISATYSV
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHC
GEEQLGTIAILGPTRMHYARVITLLQLFTKHFTEGLNGLYKSK
CHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA