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The map label for this gene is pyc [H]

Identifier: 152976361

GI number: 152976361

Start: 2736481

End: 2739927

Strand: Reverse

Name: pyc [H]

Synonym: Bcer98_2649

Alternate gene names: 152976361

Gene position: 2739927-2736481 (Counterclockwise)

Preceding gene: 152976362

Following gene: 152976359

Centisome position: 67.04

GC content: 38.0

Gene sequence:

>3447_bases
ATGACAAAGCTGCAACGCATTAAAAAAGTATTGGTAGCTAACCGTGGAGAAATTGCAATTCGTGTATTTAGAGCTTGTGC
AGAGCTTGGTTTAAGTACAGTTGCAATTTATTCAAAAGAAGATAGCCGTTCTTATCATCGATATAAAGCGGATGAATCTT
ATTTAGTGGGGGAAGGCAAGAAACCGATTGATGCTTACTTGGATATTGAAGGGATTATTGAAATTGCCAAAAATAACAAT
GTAGATGCGATTCATCCTGGTTATGGCTTCTTATCAGAAAATATTCAATTTGCAAAACGCTGTGAAGAAGAGGGAATCAT
TTTTATTGGGCCGAAGAGCAAACATCTAGATATGTTTGGGGATAAGGTAAAAGCAAGAACACAGGCGCAATTAGCAAATA
TTCCAGTTATTCCTGGTAGCGACGGACCTGTGGATTCATTAGAAGACGTTGAAGAATTTGCGACAAAATATGGGTATCCA
ATTATGATTAAAGCTTCCCTTGGTGGTGGCGGTAGAGGTATGCGTATTGTTCGTAATCATAATGAGCTGGAAGACTCATA
TAATCGAGCAAAGTCAGAAGCAAAAGCAGCTTTTGGTAACGATGAAGTATATGTTGAAAAATTTGTTGAAAAGCCTAAGC
ATATAGAAGTACAAATATTAGCAGATGAAGAAGGAAATGTCGTTCATTTATATGAGCGAGATTGCTCTGTACAACGTCGT
CATCAAAAAGTGGTTGAAATTGCACCAAGTGTGTCACTTTCGGATGACCTGCGCCATCGTATTTGTGAGGCGGCAGTGAA
GTTAACAAAAAATGTGAATTATTTAAATGCTGGTACGGTGGAATTTCTTGTGAAAGGTGATGATTTTTACTTCATCGAAG
TAAATCCACGTGTACAAGTAGAACATACGATTACAGAGATGGTTACAGGAATTGATATCGTACAATCACAAATTTTAATT
GCAGATGGCCACACTTTACATAGCGAGATTATGAGCATACCAAAACAAGAAGATATCATCATTCATGGTTATGCTATCCA
ATCACGTGTAACAACAGAAGATCCGCTCAATAACTTTATGCCTGATACAGGAAAAATTATGGCATACCGTTCAGGGGGAG
GATTCGGTGTTCGTCTTGACACAGGTAATAGCTTTCAAGGGGCAGTTATTACGCCGTACTATGATTCATTACTTGTAAAA
GTGACAACTTGGGCACTTACATTTGAACAAGCTGCTGCAAAAATGGAGCGTAACTTAAAAGAATTCCGTATTCGTGGTAT
TAAAACAAATATTCCATTCTTAGAGAATGTAGTGAAGCATAAAAATTTCTTATCAGGAGAATATGACACATCATTTATAG
ATGCATCACCTGAATTATTTGTATTCCCGAAACGTAAAGACCGTGGTACAAAAATGTTAAGCTATATCGGGACAGTAACG
GTAAATGGTTTCCCAGGAGTAGGAAAAAAAGAAAAGCCGATTTTCCCAGATGCACGTATACCAAATGTAAAACATTATGA
ACCAATCCAAACAGGTACAAAACAAATTTTAGATAAGCATGGGGCAGATGGCCTTGTAAAATGGGTACAAGATCAAAAAC
GTGTATTGTTAACAGATACAACATTCCGTGATGCCCATCAATCTCTATTAGCAACGCGTGTTCGTACGAAGGATTTAATG
CAAATTGCTGAGCCGACGGCGAGAATGTTACCAAATTTATTCTCTACAGAGATGTGGGGAGGAGCTACATTTGATGTGGC
ATACCGTTTCTTGAAAGAAGATCCATGGGAACGATTACTGCAACTTCGTGAAAGTATGCCGAATGTATTATTCCAAATGT
TACTTCGTTCAGCAAATGCAGTGGGTTACAAAAACTATCCCGATAATCTCATTCAAAAGTTTGTAGAATGTTCCGCGCAA
GCTGGTATTGATGTTTTCCGCATATTTGATAGTTTAAACTGGGTTGAAGGTATGAGCATTGCTATTAATGCTGTACGAGA
TAGCGGTAAGATTGCGGAAGCAACAATGTGCTATACAGGGGATATTCATGACCCAATGCGCAGTAAATACGATTTACAAT
ACTATAAAGACTTAGCAAAAGAACTAGAAGCATCTGGTGCTCATATTTTAGGTATTAAAGATATGGCTGGCTTATTAAAG
CCAAATGCGGCTTATGACCTCGTTTCAGCTTTAAAAGACACAGTATCAATTCCAATTCACCTTCATACACATGATACGAG
TGGAAATGGTATCTTAACGTATACGAAAGCAATTGAAGCTGGTGTTGATATTGTCGATGTAGCAGTAAGCTCTATGGCAG
GCTTAACGTCACAGCCAAGTGTAAATACGTTATACTACGCATTAGGTGGAAATGAAAGACAACCAGATGTCAATATTCAA
TCGTTAGAAAAACTTTCTCATTACTGGGAAGATATACGAAAATATTATGCTCCGTTTGAAAGTGGTATGAATGCTCCACA
TACTGAGGTATATATGCATGAAATGCCAGGCGGTCAGTATAGTAACTTGCAACAACAAGCGAAAGCAGTTGGATTAGGAG
ATCGTTTCGATGAAGTAAAAGTGATGTATCGCCGCGTGAATGATATGTTCGGAGATATTGTAAAGGTAACACCGTCATCA
AAAGTTGTTGGGGATATGGCATTGTTTATGGTACAAAACCATCTGACAGAACAAGACATTTTTGAACGTGGTCATGCTTT
AGATTTCCCAAGCTCAGTTGTTGAGATGTTCTCTGGTGACCTTGGACAGCCATATGGTGGTTTTCCAAAAGAATTACAAA
AAATTATCTTAAAAGGAAAAGAGCCGTTAACTGTAAGACCAGGTGAATTATTAGAACCCGTGGACTTTGAAGCTTTAAAA
GAAGAGTTATTCCATAAGCTAGGACGCGAAGTAACAATTTTTGATGTTGTCGCATATGCGTTATATCCAAAAGTATTTAT
GGATTATGAGAAGGTTGCAGGGCTTTATGGAGATGTATCTGTGCTGGATACTCCAACATTCTTCCATGGTATGAGACTTG
GAGAAGAAATCGGTGTTGAAATTGAACGAGGTAAAACATTGATGGTGAAATTAGTTTCAATTGGAGAACCACAACCAGAT
GGAACGCGTGTACTTTACTTTGAATTTAATGGACAACCTCGTGAAATTGTTGTGAAGGATGAAAGTATTAAGGCGACAGT
TGCACAACGAGTGAAAGGAAATCGCGAGAATCCAAATCACATTAGTGCAACAATGCCAGGGACAGTTATTAAAGTTGTTG
TGAATGAAGGCGATGAAGTCAAAAAAGGTGATTCCATGGCAATTACAGAAGCAATGAAAATGGAAACAACTGTTCAAGCG
CCGTTTAATGGAAAAGTGAAGAAAGTGTACGTGAAAGATGGAGATGCAATTCAAACAGGAGATTTATTAATTGAACTGGA
ACAATAA

Upstream 100 bases:

>100_bases
TTTCTAGATATAGATTGAAAAAGAAAGTGAAGAACTTCACGCTCTTTAAGGTGTATATCTATGTAATCTCTAGAGTGGTA
GGAAAGTAGAGGGGAAAATT

Downstream 100 bases:

>100_bases
TGATAAAAACAACTACAAGTCAGTTGAATTTTTCTAACATGGATTCGTCGTTGTAAATAATAAACATAAAGAAAACGAGC
TGCGATAAAGCAGCTCGTTT

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1148; Mature: 1147

Protein sequence:

>1148_residues
MTKLQRIKKVLVANRGEIAIRVFRACAELGLSTVAIYSKEDSRSYHRYKADESYLVGEGKKPIDAYLDIEGIIEIAKNNN
VDAIHPGYGFLSENIQFAKRCEEEGIIFIGPKSKHLDMFGDKVKARTQAQLANIPVIPGSDGPVDSLEDVEEFATKYGYP
IMIKASLGGGGRGMRIVRNHNELEDSYNRAKSEAKAAFGNDEVYVEKFVEKPKHIEVQILADEEGNVVHLYERDCSVQRR
HQKVVEIAPSVSLSDDLRHRICEAAVKLTKNVNYLNAGTVEFLVKGDDFYFIEVNPRVQVEHTITEMVTGIDIVQSQILI
ADGHTLHSEIMSIPKQEDIIIHGYAIQSRVTTEDPLNNFMPDTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVK
VTTWALTFEQAAAKMERNLKEFRIRGIKTNIPFLENVVKHKNFLSGEYDTSFIDASPELFVFPKRKDRGTKMLSYIGTVT
VNGFPGVGKKEKPIFPDARIPNVKHYEPIQTGTKQILDKHGADGLVKWVQDQKRVLLTDTTFRDAHQSLLATRVRTKDLM
QIAEPTARMLPNLFSTEMWGGATFDVAYRFLKEDPWERLLQLRESMPNVLFQMLLRSANAVGYKNYPDNLIQKFVECSAQ
AGIDVFRIFDSLNWVEGMSIAINAVRDSGKIAEATMCYTGDIHDPMRSKYDLQYYKDLAKELEASGAHILGIKDMAGLLK
PNAAYDLVSALKDTVSIPIHLHTHDTSGNGILTYTKAIEAGVDIVDVAVSSMAGLTSQPSVNTLYYALGGNERQPDVNIQ
SLEKLSHYWEDIRKYYAPFESGMNAPHTEVYMHEMPGGQYSNLQQQAKAVGLGDRFDEVKVMYRRVNDMFGDIVKVTPSS
KVVGDMALFMVQNHLTEQDIFERGHALDFPSSVVEMFSGDLGQPYGGFPKELQKIILKGKEPLTVRPGELLEPVDFEALK
EELFHKLGREVTIFDVVAYALYPKVFMDYEKVAGLYGDVSVLDTPTFFHGMRLGEEIGVEIERGKTLMVKLVSIGEPQPD
GTRVLYFEFNGQPREIVVKDESIKATVAQRVKGNRENPNHISATMPGTVIKVVVNEGDEVKKGDSMAITEAMKMETTVQA
PFNGKVKKVYVKDGDAIQTGDLLIELEQ

Sequences:

>Translated_1148_residues
MTKLQRIKKVLVANRGEIAIRVFRACAELGLSTVAIYSKEDSRSYHRYKADESYLVGEGKKPIDAYLDIEGIIEIAKNNN
VDAIHPGYGFLSENIQFAKRCEEEGIIFIGPKSKHLDMFGDKVKARTQAQLANIPVIPGSDGPVDSLEDVEEFATKYGYP
IMIKASLGGGGRGMRIVRNHNELEDSYNRAKSEAKAAFGNDEVYVEKFVEKPKHIEVQILADEEGNVVHLYERDCSVQRR
HQKVVEIAPSVSLSDDLRHRICEAAVKLTKNVNYLNAGTVEFLVKGDDFYFIEVNPRVQVEHTITEMVTGIDIVQSQILI
ADGHTLHSEIMSIPKQEDIIIHGYAIQSRVTTEDPLNNFMPDTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVK
VTTWALTFEQAAAKMERNLKEFRIRGIKTNIPFLENVVKHKNFLSGEYDTSFIDASPELFVFPKRKDRGTKMLSYIGTVT
VNGFPGVGKKEKPIFPDARIPNVKHYEPIQTGTKQILDKHGADGLVKWVQDQKRVLLTDTTFRDAHQSLLATRVRTKDLM
QIAEPTARMLPNLFSTEMWGGATFDVAYRFLKEDPWERLLQLRESMPNVLFQMLLRSANAVGYKNYPDNLIQKFVECSAQ
AGIDVFRIFDSLNWVEGMSIAINAVRDSGKIAEATMCYTGDIHDPMRSKYDLQYYKDLAKELEASGAHILGIKDMAGLLK
PNAAYDLVSALKDTVSIPIHLHTHDTSGNGILTYTKAIEAGVDIVDVAVSSMAGLTSQPSVNTLYYALGGNERQPDVNIQ
SLEKLSHYWEDIRKYYAPFESGMNAPHTEVYMHEMPGGQYSNLQQQAKAVGLGDRFDEVKVMYRRVNDMFGDIVKVTPSS
KVVGDMALFMVQNHLTEQDIFERGHALDFPSSVVEMFSGDLGQPYGGFPKELQKIILKGKEPLTVRPGELLEPVDFEALK
EELFHKLGREVTIFDVVAYALYPKVFMDYEKVAGLYGDVSVLDTPTFFHGMRLGEEIGVEIERGKTLMVKLVSIGEPQPD
GTRVLYFEFNGQPREIVVKDESIKATVAQRVKGNRENPNHISATMPGTVIKVVVNEGDEVKKGDSMAITEAMKMETTVQA
PFNGKVKKVYVKDGDAIQTGDLLIELEQ
>Mature_1147_residues
TKLQRIKKVLVANRGEIAIRVFRACAELGLSTVAIYSKEDSRSYHRYKADESYLVGEGKKPIDAYLDIEGIIEIAKNNNV
DAIHPGYGFLSENIQFAKRCEEEGIIFIGPKSKHLDMFGDKVKARTQAQLANIPVIPGSDGPVDSLEDVEEFATKYGYPI
MIKASLGGGGRGMRIVRNHNELEDSYNRAKSEAKAAFGNDEVYVEKFVEKPKHIEVQILADEEGNVVHLYERDCSVQRRH
QKVVEIAPSVSLSDDLRHRICEAAVKLTKNVNYLNAGTVEFLVKGDDFYFIEVNPRVQVEHTITEMVTGIDIVQSQILIA
DGHTLHSEIMSIPKQEDIIIHGYAIQSRVTTEDPLNNFMPDTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVKV
TTWALTFEQAAAKMERNLKEFRIRGIKTNIPFLENVVKHKNFLSGEYDTSFIDASPELFVFPKRKDRGTKMLSYIGTVTV
NGFPGVGKKEKPIFPDARIPNVKHYEPIQTGTKQILDKHGADGLVKWVQDQKRVLLTDTTFRDAHQSLLATRVRTKDLMQ
IAEPTARMLPNLFSTEMWGGATFDVAYRFLKEDPWERLLQLRESMPNVLFQMLLRSANAVGYKNYPDNLIQKFVECSAQA
GIDVFRIFDSLNWVEGMSIAINAVRDSGKIAEATMCYTGDIHDPMRSKYDLQYYKDLAKELEASGAHILGIKDMAGLLKP
NAAYDLVSALKDTVSIPIHLHTHDTSGNGILTYTKAIEAGVDIVDVAVSSMAGLTSQPSVNTLYYALGGNERQPDVNIQS
LEKLSHYWEDIRKYYAPFESGMNAPHTEVYMHEMPGGQYSNLQQQAKAVGLGDRFDEVKVMYRRVNDMFGDIVKVTPSSK
VVGDMALFMVQNHLTEQDIFERGHALDFPSSVVEMFSGDLGQPYGGFPKELQKIILKGKEPLTVRPGELLEPVDFEALKE
ELFHKLGREVTIFDVVAYALYPKVFMDYEKVAGLYGDVSVLDTPTFFHGMRLGEEIGVEIERGKTLMVKLVSIGEPQPDG
TRVLYFEFNGQPREIVVKDESIKATVAQRVKGNRENPNHISATMPGTVIKVVVNEGDEVKKGDSMAITEAMKMETTVQAP
FNGKVKKVYVKDGDAIQTGDLLIELEQ

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1146, Percent_Identity=51.2216404886562, Blast_Score=1147, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1146, Percent_Identity=51.2216404886562, Blast_Score=1147, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1146, Percent_Identity=51.2216404886562, Blast_Score=1147, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=452, Percent_Identity=44.2477876106195, Blast_Score=394, Evalue=1e-109,
Organism=Homo sapiens, GI189095269, Length=464, Percent_Identity=42.6724137931034, Blast_Score=365, Evalue=1e-100,
Organism=Homo sapiens, GI65506442, Length=456, Percent_Identity=43.2017543859649, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI295821183, Length=456, Percent_Identity=43.2017543859649, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI38679960, Length=508, Percent_Identity=31.8897637795276, Blast_Score=241, Evalue=2e-63,
Organism=Homo sapiens, GI38679977, Length=508, Percent_Identity=31.8897637795276, Blast_Score=241, Evalue=3e-63,
Organism=Homo sapiens, GI38679967, Length=508, Percent_Identity=31.8897637795276, Blast_Score=241, Evalue=3e-63,
Organism=Homo sapiens, GI38679971, Length=508, Percent_Identity=31.8897637795276, Blast_Score=241, Evalue=3e-63,
Organism=Homo sapiens, GI38679974, Length=508, Percent_Identity=31.8897637795276, Blast_Score=241, Evalue=3e-63,
Organism=Homo sapiens, GI134142062, Length=509, Percent_Identity=30.4518664047151, Blast_Score=235, Evalue=2e-61,
Organism=Escherichia coli, GI1789654, Length=449, Percent_Identity=45.6570155902004, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI1786216, Length=321, Percent_Identity=22.4299065420561, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562816, Length=1150, Percent_Identity=50.3478260869565, Blast_Score=1134, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17567343, Length=470, Percent_Identity=42.5531914893617, Blast_Score=358, Evalue=1e-98,
Organism=Caenorhabditis elegans, GI71987519, Length=498, Percent_Identity=40.7630522088353, Blast_Score=355, Evalue=1e-97,
Organism=Caenorhabditis elegans, GI71997168, Length=513, Percent_Identity=29.6296296296296, Blast_Score=207, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI71997163, Length=513, Percent_Identity=29.6296296296296, Blast_Score=207, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI133931226, Length=494, Percent_Identity=30.3643724696356, Blast_Score=206, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1157, Percent_Identity=49.7839239412273, Blast_Score=1108, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1160, Percent_Identity=49.1379310344828, Blast_Score=1093, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=450, Percent_Identity=38, Blast_Score=302, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6324343, Length=512, Percent_Identity=31.0546875, Blast_Score=235, Evalue=3e-62,
Organism=Saccharomyces cerevisiae, GI6323863, Length=437, Percent_Identity=34.324942791762, Blast_Score=231, Evalue=6e-61,
Organism=Saccharomyces cerevisiae, GI6322331, Length=303, Percent_Identity=22.1122112211221, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322569, Length=222, Percent_Identity=23.4234234234234, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24652212, Length=1147, Percent_Identity=51.0026155187446, Blast_Score=1155, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1147, Percent_Identity=51.0026155187446, Blast_Score=1155, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1147, Percent_Identity=51.0026155187446, Blast_Score=1155, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1147, Percent_Identity=51.0026155187446, Blast_Score=1155, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1147, Percent_Identity=51.0026155187446, Blast_Score=1155, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1164, Percent_Identity=50.5154639175258, Blast_Score=1149, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1164, Percent_Identity=50.5154639175258, Blast_Score=1149, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1164, Percent_Identity=50.5154639175258, Blast_Score=1149, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1164, Percent_Identity=50.5154639175258, Blast_Score=1149, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1164, Percent_Identity=50.5154639175258, Blast_Score=1149, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=508, Percent_Identity=40.3543307086614, Blast_Score=374, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24651759, Length=465, Percent_Identity=39.5698924731183, Blast_Score=331, Evalue=2e-90,
Organism=Drosophila melanogaster, GI161076407, Length=504, Percent_Identity=31.547619047619, Blast_Score=236, Evalue=6e-62,
Organism=Drosophila melanogaster, GI24586460, Length=504, Percent_Identity=31.547619047619, Blast_Score=236, Evalue=6e-62,
Organism=Drosophila melanogaster, GI161076409, Length=504, Percent_Identity=31.547619047619, Blast_Score=236, Evalue=6e-62,
Organism=Drosophila melanogaster, GI24586458, Length=504, Percent_Identity=31.547619047619, Blast_Score=236, Evalue=6e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 128484; Mature: 128352

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLQRIKKVLVANRGEIAIRVFRACAELGLSTVAIYSKEDSRSYHRYKADESYLVGEGK
CCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHCCCCCCEEECCCC
KPIDAYLDIEGIIEIAKNNNVDAIHPGYGFLSENIQFAKRCEEEGIIFIGPKSKHLDMFG
CCHHHHCCHHHHHEEECCCCCCEECCCCCHHHHCHHHHHHHCCCCEEEECCCCCCHHHHH
DKVKARTQAQLANIPVIPGSDGPVDSLEDVEEFATKYGYPIMIKASLGGGGRGMRIVRNH
HHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECC
NELEDSYNRAKSEAKAAFGNDEVYVEKFVEKPKHIEVQILADEEGNVVHLYERDCSVQRR
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCHHHHH
HQKVVEIAPSVSLSDDLRHRICEAAVKLTKNVNYLNAGTVEFLVKGDDFYFIEVNPRVQV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCEEEEEECCCEEE
EHTITEMVTGIDIVQSQILIADGHTLHSEIMSIPKQEDIIIHGYAIQSRVTTEDPLNNFM
HHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCHHHCC
PDTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVKVTTWALTFEQAAAKMERNLK
CCCCCEEEEECCCCEEEEEECCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCHH
EFRIRGIKTNIPFLENVVKHKNFLSGEYDTSFIDASPELFVFPKRKDRGTKMLSYIGTVT
HHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEECCCCCEEEEECCCCCHHHHHHHHEEEE
VNGFPGVGKKEKPIFPDARIPNVKHYEPIQTGTKQILDKHGADGLVKWVQDQKRVLLTDT
ECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEC
TFRDAHQSLLATRVRTKDLMQIAEPTARMLPNLFSTEMWGGATFDVAYRFLKEDPWERLL
CHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHCCCCCHHHHHHHHHHCCHHHHHH
QLRESMPNVLFQMLLRSANAVGYKNYPDNLIQKFVECSAQAGIDVFRIFDSLNWVEGMSI
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHCCCCE
AINAVRDSGKIAEATMCYTGDIHDPMRSKYDLQYYKDLAKELEASGAHILGIKDMAGLLK
EEEEECCCCCEEEEEEEEECCCCCHHHCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHC
PNAAYDLVSALKDTVSIPIHLHTHDTSGNGILTYTKAIEAGVDIVDVAVSSMAGLTSQPS
CCHHHHHHHHHHHHEEEEEEEEECCCCCCEEEEEHHHHHCCCHHHHHHHHHHCCCCCCCC
VNTLYYALGGNERQPDVNIQSLEKLSHYWEDIRKYYAPFESGMNAPHTEVYMHEMPGGQY
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCH
SNLQQQAKAVGLGDRFDEVKVMYRRVNDMFGDIVKVTPSSKVVGDMALFMVQNHLTEQDI
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCHHHH
FERGHALDFPSSVVEMFSGDLGQPYGGFPKELQKIILKGKEPLTVRPGELLEPVDFEALK
HHCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHH
EELFHKLGREVTIFDVVAYALYPKVFMDYEKVAGLYGDVSVLDTPTFFHGMRLGEEIGVE
HHHHHHHCCCEEHHHHHHHHHHHHHHHCHHHHHCCCCCCEEECCCHHHHHHHCCHHHCEE
IERGKTLMVKLVSIGEPQPDGTRVLYFEFNGQPREIVVKDESIKATVAQRVKGNRENPNH
EECCCEEEEEEEECCCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHCCCCCCCCE
ISATMPGTVIKVVVNEGDEVKKGDSMAITEAMKMETTVQAPFNGKVKKVYVKDGDAIQTG
EEECCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHEEEECCCCCCEEEEEEECCCEEEEC
DLLIELEQ
CEEEEECC
>Mature Secondary Structure 
TKLQRIKKVLVANRGEIAIRVFRACAELGLSTVAIYSKEDSRSYHRYKADESYLVGEGK
CHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHCCCCCCEEECCCC
KPIDAYLDIEGIIEIAKNNNVDAIHPGYGFLSENIQFAKRCEEEGIIFIGPKSKHLDMFG
CCHHHHCCHHHHHEEECCCCCCEECCCCCHHHHCHHHHHHHCCCCEEEECCCCCCHHHHH
DKVKARTQAQLANIPVIPGSDGPVDSLEDVEEFATKYGYPIMIKASLGGGGRGMRIVRNH
HHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECC
NELEDSYNRAKSEAKAAFGNDEVYVEKFVEKPKHIEVQILADEEGNVVHLYERDCSVQRR
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCHHHHH
HQKVVEIAPSVSLSDDLRHRICEAAVKLTKNVNYLNAGTVEFLVKGDDFYFIEVNPRVQV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCEEEEEECCCEEE
EHTITEMVTGIDIVQSQILIADGHTLHSEIMSIPKQEDIIIHGYAIQSRVTTEDPLNNFM
HHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCHHHCC
PDTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVKVTTWALTFEQAAAKMERNLK
CCCCCEEEEECCCCEEEEEECCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCHH
EFRIRGIKTNIPFLENVVKHKNFLSGEYDTSFIDASPELFVFPKRKDRGTKMLSYIGTVT
HHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEECCCCCEEEEECCCCCHHHHHHHHEEEE
VNGFPGVGKKEKPIFPDARIPNVKHYEPIQTGTKQILDKHGADGLVKWVQDQKRVLLTDT
ECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEC
TFRDAHQSLLATRVRTKDLMQIAEPTARMLPNLFSTEMWGGATFDVAYRFLKEDPWERLL
CHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHCCCCCHHHHHHHHHHCCHHHHHH
QLRESMPNVLFQMLLRSANAVGYKNYPDNLIQKFVECSAQAGIDVFRIFDSLNWVEGMSI
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHCCCCE
AINAVRDSGKIAEATMCYTGDIHDPMRSKYDLQYYKDLAKELEASGAHILGIKDMAGLLK
EEEEECCCCCEEEEEEEEECCCCCHHHCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHC
PNAAYDLVSALKDTVSIPIHLHTHDTSGNGILTYTKAIEAGVDIVDVAVSSMAGLTSQPS
CCHHHHHHHHHHHHEEEEEEEEECCCCCCEEEEEHHHHHCCCHHHHHHHHHHCCCCCCCC
VNTLYYALGGNERQPDVNIQSLEKLSHYWEDIRKYYAPFESGMNAPHTEVYMHEMPGGQY
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCH
SNLQQQAKAVGLGDRFDEVKVMYRRVNDMFGDIVKVTPSSKVVGDMALFMVQNHLTEQDI
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCHHHH
FERGHALDFPSSVVEMFSGDLGQPYGGFPKELQKIILKGKEPLTVRPGELLEPVDFEALK
HHCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHH
EELFHKLGREVTIFDVVAYALYPKVFMDYEKVAGLYGDVSVLDTPTFFHGMRLGEEIGVE
HHHHHHHCCCEEHHHHHHHHHHHHHHHCHHHHHCCCCCCEEECCCHHHHHHHCCHHHCEE
IERGKTLMVKLVSIGEPQPDGTRVLYFEFNGQPREIVVKDESIKATVAQRVKGNRENPNH
EECCCEEEEEEEECCCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHCCCCCCCCE
ISATMPGTVIKVVVNEGDEVKKGDSMAITEAMKMETTVQAPFNGKVKKVYVKDGDAIQTG
EEECCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHEEEECCCCCCEEEEEEECCCEEEEC
DLLIELEQ
CEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]