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The map label for this gene is ctaB2 [H]

Identifier: 152976359

GI number: 152976359

Start: 2734014

End: 2734940

Strand: Reverse

Name: ctaB2 [H]

Synonym: Bcer98_2647

Alternate gene names: 152976359

Gene position: 2734940-2734014 (Counterclockwise)

Preceding gene: 152976361

Following gene: 152976358

Centisome position: 66.92

GC content: 36.79

Gene sequence:

>927_bases
ATGATGAACCATGCAACAAGTGAGCTGCATGATGAGTCAGCTGTAACAGATGTACCGGAGACAACGCGTGTACAAGATTT
ATTAGCGCTCGTTAAAATGGGGATTGTCAATTCAAATACATTAACTGTATTTACTGGATTTTGGTTAGCGCTACATTTTA
ATGGGTTGAATGCTTTAGAGCATTTAGATAAAATGTTCTTTACAATCGTAGGTTCCGCACTCATTATGGCTGGGTCATGT
AGCTTAAATAACTATATTGATCGCGATATTGATCACTTAATGGAACGGACAAAAAACCGTCCGACGGTAACAGGAAAATA
TAAACCTGGATTTGTATTAACGCTAGGTGTTACTTTATTGCTTCTTGGATTTGTATTTTTGTTGTTGACAACAGCGATGG
CAGCACTTATAGGTTTTATTGGTGCTTTCACATATGTTGTTTTATATTCTTTGTGGACAAAAAGAGCATATACGCTAAAT
ACAGTGGTAGGTAGCGTATCTGGAGCGGTTCCACCTTTAATTGGTTGGGCGGCAATTCATCCTAGCTTAGATCATCCAAT
TGCTTGGATGTTATTCTTGATTATGTTTATTTGGCAAATCCCACATTTCCTCGCTTTGGCGATGAAGCGTGTTGATGAAT
ATCGAAACGCAGGAATTCCAATGCTTCCGGTTGTTCATGGATTTGATATTACAAAACGCCAAATTATGATTTGGACAGTA
TGTTTATTACCATTACCATTTTATATGAGTGGGCTTGGCATAACATTTATGATAATTGCAACATTGCTTAACATCGGATG
GATTGTTTTGGGATTCTATGGATTCCGTAAGAAAGATGACATCAAATGGTCCGTTCAAATGTTTGTCTACTCCTTGAATT
ATTTGACAATCTTATTTGTGTCAATGATTGTAGTTACATTCTTCTAA

Upstream 100 bases:

>100_bases
TTAACAATATTTCTATTGTAATAATATAGCCATATAGAAGCGCGCTGCTTTAGAGAGTCTAAGCATAGAAGAAGGACGAA
TGTTTTAAGAGGGGGTTGAA

Downstream 100 bases:

>100_bases
GACAACGACACGAGTGGATTTCTTTACGTTGAGATTTACTTTACTTATTATAAAGTATAATCTAATTCACAAAGAAAGTG
GGGGTTGTTTGTATGAAGAA

Product: protoheme IX farnesyltransferase

Products: NA

Alternate protein names: Heme B farnesyltransferase 2; Heme O synthase 2 [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MMNHATSELHDESAVTDVPETTRVQDLLALVKMGIVNSNTLTVFTGFWLALHFNGLNALEHLDKMFFTIVGSALIMAGSC
SLNNYIDRDIDHLMERTKNRPTVTGKYKPGFVLTLGVTLLLLGFVFLLLTTAMAALIGFIGAFTYVVLYSLWTKRAYTLN
TVVGSVSGAVPPLIGWAAIHPSLDHPIAWMLFLIMFIWQIPHFLALAMKRVDEYRNAGIPMLPVVHGFDITKRQIMIWTV
CLLPLPFYMSGLGITFMIIATLLNIGWIVLGFYGFRKKDDIKWSVQMFVYSLNYLTILFVSMIVVTFF

Sequences:

>Translated_308_residues
MMNHATSELHDESAVTDVPETTRVQDLLALVKMGIVNSNTLTVFTGFWLALHFNGLNALEHLDKMFFTIVGSALIMAGSC
SLNNYIDRDIDHLMERTKNRPTVTGKYKPGFVLTLGVTLLLLGFVFLLLTTAMAALIGFIGAFTYVVLYSLWTKRAYTLN
TVVGSVSGAVPPLIGWAAIHPSLDHPIAWMLFLIMFIWQIPHFLALAMKRVDEYRNAGIPMLPVVHGFDITKRQIMIWTV
CLLPLPFYMSGLGITFMIIATLLNIGWIVLGFYGFRKKDDIKWSVQMFVYSLNYLTILFVSMIVVTFF
>Mature_308_residues
MMNHATSELHDESAVTDVPETTRVQDLLALVKMGIVNSNTLTVFTGFWLALHFNGLNALEHLDKMFFTIVGSALIMAGSC
SLNNYIDRDIDHLMERTKNRPTVTGKYKPGFVLTLGVTLLLLGFVFLLLTTAMAALIGFIGAFTYVVLYSLWTKRAYTLN
TVVGSVSGAVPPLIGWAAIHPSLDHPIAWMLFLIMFIWQIPHFLALAMKRVDEYRNAGIPMLPVVHGFDITKRQIMIWTV
CLLPLPFYMSGLGITFMIIATLLNIGWIVLGFYGFRKKDDIKWSVQMFVYSLNYLTILFVSMIVVTFF

Specific function: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group [H]

COG id: COG0109

COG function: function code O; Polyprenyltransferase (cytochrome oxidase assembly factor)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI17921982, Length=215, Percent_Identity=31.6279069767442, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1786631, Length=287, Percent_Identity=34.8432055749129, Blast_Score=163, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71998235, Length=234, Percent_Identity=30.3418803418803, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6325085, Length=254, Percent_Identity=29.5275590551181, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19921064, Length=233, Percent_Identity=31.7596566523605, Blast_Score=98, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006369
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 34674; Mature: 34674

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNHATSELHDESAVTDVPETTRVQDLLALVKMGIVNSNTLTVFTGFWLALHFNGLNALE
CCCCCHHHHHCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHH
HLDKMFFTIVGSALIMAGSCSLNNYIDRDIDHLMERTKNRPTVTGKYKPGFVLTLGVTLL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHH
LLGFVFLLLTTAMAALIGFIGAFTYVVLYSLWTKRAYTLNTVVGSVSGAVPPLIGWAAIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
PSLDHPIAWMLFLIMFIWQIPHFLALAMKRVDEYRNAGIPMLPVVHGFDITKRQIMIWTV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHH
CLLPLPFYMSGLGITFMIIATLLNIGWIVLGFYGFRKKDDIKWSVQMFVYSLNYLTILFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
SMIVVTFF
HHHHHHCC
>Mature Secondary Structure
MMNHATSELHDESAVTDVPETTRVQDLLALVKMGIVNSNTLTVFTGFWLALHFNGLNALE
CCCCCHHHHHCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHH
HLDKMFFTIVGSALIMAGSCSLNNYIDRDIDHLMERTKNRPTVTGKYKPGFVLTLGVTLL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHH
LLGFVFLLLTTAMAALIGFIGAFTYVVLYSLWTKRAYTLNTVVGSVSGAVPPLIGWAAIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
PSLDHPIAWMLFLIMFIWQIPHFLALAMKRVDEYRNAGIPMLPVVHGFDITKRQIMIWTV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHH
CLLPLPFYMSGLGITFMIIATLLNIGWIVLGFYGFRKKDDIKWSVQMFVYSLNYLTILFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
SMIVVTFF
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA