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The map label for this gene is mraY [H]

Identifier: 152976275

GI number: 152976275

Start: 2663222

End: 2664196

Strand: Reverse

Name: mraY [H]

Synonym: Bcer98_2563

Alternate gene names: 152976275

Gene position: 2664196-2663222 (Counterclockwise)

Preceding gene: 152976276

Following gene: 152976274

Centisome position: 65.19

GC content: 37.13

Gene sequence:

>975_bases
GTGCTTGAACAAGGTTTATTAGTAACGGCTGGGGTAGCGTTCTTAATTTCAGTTGCCCTTTCGCCATTGTTTATTCCGTT
TTTACGAAAATTAAAGTTTGGACAGAGCATTCGCGATGAAGGACCGAAATCACATCAAAAAAAATCAGGAACACCAACGA
TGGGTGGTATTGTTATTTATGTGTCTATGATGGTAACAACACTCATTATGGCAATTAAGTTTGAACATTTAGGTGCAGAA
GTGTCATTACTATTATTAGTAACGTTTGGTTACGGGTTGATTGGTTTTTTAGATGATTATATAAAAGTCGTTAAGAAACG
TAACCTAGGTTTAACGTCAAAACAGAAACTACTTGGGCAACTGATTATTGCCATTGCGTTTTTTGCTATTGCGAAAGGGC
AAGGGTTTGATACACATTTAATGATTCCAGGAACTGATATTACATTTGATTTATACTGGGCATATTTTATTCTTGTGTTG
TTTATGCTCATTGGGGGATCAAATGCAGTCAATTTGACAGATGGCCTAGATGGATTACTATCAGGAACAGCCGCTATCGC
ATTTGGTGCGTTTAGTATCATAGCAGTAGCGCAAGAACAATATGCAGTAGCGATTTTCTGTATGGCAGTTGTAGGGGCTG
TACTTGGATTCTTAGTATTTAATGCGAACCCTGCCAAAGTCTTTATGGGTGATACAGGCTCACTTGCTTTAGGGGGCGCA
ATTGCAGCTGTGGCGATTTTGTTAAAACAAGAATTATTACTTGTTATTATTGGCGGCGTATTTGTAATGGAAACTTTATC
TGTTATTATCCAAGTTATTTCATTTAAAACAACTGGAAAACGTGTCTTTAAAATGAGTCCACTACATCATCATTATGAAT
TATGTGGTTGGTCAGAATGGCGTGTTGTTGTAACATTTTGGTCTGTAGGATTTTTACTAGCAGTATTAGGAATTTATATC
GGGGTGTGGATGTAA

Upstream 100 bases:

>100_bases
GGAAAAGAAGTACATCATTTTGACGATCGTGAAGTTGCTAAAGAAGCAATCACAGAACGTTTAAACAACAGAGAGTAACA
ACATGAGAGGGGGACTACAT

Downstream 100 bases:

>100_bases
TTGAAAACGGTAACTGATTATCAAAATAAAAATATTCTTGTATTAGGTATTGCAAAAAGTGGGTATGCAGCAGCAAATTT
ATTAAAAAGCTTAGGAGCAA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIYVSMMVTTLIMAIKFEHLGAE
VSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLLGQLIIAIAFFAIAKGQGFDTHLMIPGTDITFDLYWAYFILVL
FMLIGGSNAVNLTDGLDGLLSGTAAIAFGAFSIIAVAQEQYAVAIFCMAVVGAVLGFLVFNANPAKVFMGDTGSLALGGA
IAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEWRVVVTFWSVGFLLAVLGIYI
GVWM

Sequences:

>Translated_324_residues
MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIYVSMMVTTLIMAIKFEHLGAE
VSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLLGQLIIAIAFFAIAKGQGFDTHLMIPGTDITFDLYWAYFILVL
FMLIGGSNAVNLTDGLDGLLSGTAAIAFGAFSIIAVAQEQYAVAIFCMAVVGAVLGFLVFNANPAKVFMGDTGSLALGGA
IAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEWRVVVTFWSVGFLLAVLGIYI
GVWM
>Mature_324_residues
MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIYVSMMVTTLIMAIKFEHLGAE
VSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLLGQLIIAIAFFAIAKGQGFDTHLMIPGTDITFDLYWAYFILVL
FMLIGGSNAVNLTDGLDGLLSGTAAIAFGAFSIIAVAQEQYAVAIFCMAVVGAVLGFLVFNANPAKVFMGDTGSLALGGA
IAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEWRVVVTFWSVGFLLAVLGIYI
GVWM

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=325, Percent_Identity=46.4615384615385, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1790218, Length=206, Percent_Identity=29.126213592233, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 34997; Mature: 34997

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHCCCCCCCCHHHHHHH
VSMMVTTLIMAIKFEHLGAEVSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLLGQ
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LIIAIAFFAIAKGQGFDTHLMIPGTDITFDLYWAYFILVLFMLIGGSNAVNLTDGLDGLL
HHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHH
SGTAAIAFGAFSIIAVAQEQYAVAIFCMAVVGAVLGFLVFNANPAKVFMGDTGSLALGGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHH
IAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCHHHHHHCCCCCH
RVVVTFWSVGFLLAVLGIYIGVWM
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHCCCCCCCCHHHHHHH
VSMMVTTLIMAIKFEHLGAEVSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLLGQ
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LIIAIAFFAIAKGQGFDTHLMIPGTDITFDLYWAYFILVLFMLIGGSNAVNLTDGLDGLL
HHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHH
SGTAAIAFGAFSIIAVAQEQYAVAIFCMAVVGAVLGFLVFNANPAKVFMGDTGSLALGGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHH
IAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCHHHHHHCCCCCH
RVVVTFWSVGFLLAVLGIYIGVWM
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA