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The map label for this gene is rnhB

Identifier: 152976203

GI number: 152976203

Start: 2588658

End: 2589437

Strand: Reverse

Name: rnhB

Synonym: Bcer98_2489

Alternate gene names: 152976203

Gene position: 2589437-2588658 (Counterclockwise)

Preceding gene: 152976204

Following gene: 152976202

Centisome position: 63.36

GC content: 39.49

Gene sequence:

>780_bases
ATGGGCAAATGGACAATTAAAGAAGCAAGTGAATTATTGCAAGAAATTGGAACGGAAGAGGATGAGCGCTTTCAAATATT
ATTGAAAGATGAGCGAAAAGGAATTCAAAATTTAATCTCCAAATGGCGAAAACAGAAGAAGAAAATGCAAGAAGAGAAAG
AACAATTTCTAGAAATGTCTAAATATGAAAATGCATTACGCAAGCAGGGGATTTCCTATATTGCTGGCATAGATGAAGTT
GGAAGAGGCCCCTTAGCTGGACCTGTTGTAACGGCCGCTGTCATTCTTCCAGAGGAATTCTATATACCAGGGCTAAATGA
CTCGAAAAAGCTCAGTGAAGCAAAGCGTGAGCTGTTTTATGATGAGATTAGAGAGAAAGCTATTGCAATTGGCGTTGGGA
TTGTCTCGCCTCAAGTGATTGATGAAATGAATATTTATCAAGCGACGAAACGAGCGATGTTAGATGCGGTTGCCAATTTA
TCTTATGCACCAGAGCATTTATTAATCGATGCAATGAAACTACCGACATCGATTCCTCAAACATCGATTGTGAAAGGAGA
CGCGAAAAGTATTTCTATTTCTGCAGCCTCCATTATCGCCAAGGTTACTCGTGACCGAATGATGAAAGAGCTGGGCAAAA
CATATCCTGAGTATGGTTTTGAAAAACATATGGGTTATGGTACGAAACAACATTTAGAAGCAATCGAGACATACGGAGTG
CTAGAAGAGCACCGCAAAACCTTTGCTCCCATTAAAGACATGATAAAAAATAAGCTGTGA

Upstream 100 bases:

>100_bases
AGAATGACATTTGAATCACCGGAGGAATTTGCAGAAGAAGCATAAGAAGACGTGCGGTTGTACGTCTTTTTTTTGAGTGT
TTCAAAAAGGGGGACAGATC

Downstream 100 bases:

>100_bases
ATCTACAGCTTATTTTTTTATTTTCGTATATGAACATTACTATTTTCCAAAAAGAATAAAGCGATTTCAGTTTTCTGACA
CTTTATTGTAGACATGGTGG

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MGKWTIKEASELLQEIGTEEDERFQILLKDERKGIQNLISKWRKQKKKMQEEKEQFLEMSKYENALRKQGISYIAGIDEV
GRGPLAGPVVTAAVILPEEFYIPGLNDSKKLSEAKRELFYDEIREKAIAIGVGIVSPQVIDEMNIYQATKRAMLDAVANL
SYAPEHLLIDAMKLPTSIPQTSIVKGDAKSISISAASIIAKVTRDRMMKELGKTYPEYGFEKHMGYGTKQHLEAIETYGV
LEEHRKTFAPIKDMIKNKL

Sequences:

>Translated_259_residues
MGKWTIKEASELLQEIGTEEDERFQILLKDERKGIQNLISKWRKQKKKMQEEKEQFLEMSKYENALRKQGISYIAGIDEV
GRGPLAGPVVTAAVILPEEFYIPGLNDSKKLSEAKRELFYDEIREKAIAIGVGIVSPQVIDEMNIYQATKRAMLDAVANL
SYAPEHLLIDAMKLPTSIPQTSIVKGDAKSISISAASIIAKVTRDRMMKELGKTYPEYGFEKHMGYGTKQHLEAIETYGV
LEEHRKTFAPIKDMIKNKL
>Mature_258_residues
GKWTIKEASELLQEIGTEEDERFQILLKDERKGIQNLISKWRKQKKKMQEEKEQFLEMSKYENALRKQGISYIAGIDEVG
RGPLAGPVVTAAVILPEEFYIPGLNDSKKLSEAKRELFYDEIREKAIAIGVGIVSPQVIDEMNIYQATKRAMLDAVANLS
YAPEHLLIDAMKLPTSIPQTSIVKGDAKSISISAASIIAKVTRDRMMKELGKTYPEYGFEKHMGYGTKQHLEAIETYGVL
EEHRKTFAPIKDMIKNKL

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=180, Percent_Identity=53.3333333333333, Blast_Score=186, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17536263, Length=173, Percent_Identity=32.9479768786127, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_BACCN (A7GRG7)

Other databases:

- EMBL:   CP000764
- RefSeq:   YP_001375720.1
- ProteinModelPortal:   A7GRG7
- SMR:   A7GRG7
- STRING:   A7GRG7
- EnsemblBacteria:   EBBACT00000039363
- GeneID:   5345713
- GenomeReviews:   CP000764_GR
- KEGG:   bcy:Bcer98_2489
- eggNOG:   COG0164
- GeneTree:   EBGT00050000002677
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- ProtClustDB:   PRK00015
- BioCyc:   BCER315749:BCER98_2489-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 29350; Mature: 29219

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKWTIKEASELLQEIGTEEDERFQILLKDERKGIQNLISKWRKQKKKMQEEKEQFLEMS
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYENALRKQGISYIAGIDEVGRGPLAGPVVTAAVILPEEFYIPGLNDSKKLSEAKRELFY
HHHHHHHHCCHHHHHCHHHHCCCCCCHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHH
DEIREKAIAIGVGIVSPQVIDEMNIYQATKRAMLDAVANLSYAPEHLLIDAMKLPTSIPQ
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
TSIVKGDAKSISISAASIIAKVTRDRMMKELGKTYPEYGFEKHMGYGTKQHLEAIETYGV
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCHHHHCCCCHHHHHHHHHHHHH
LEEHRKTFAPIKDMIKNKL
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GKWTIKEASELLQEIGTEEDERFQILLKDERKGIQNLISKWRKQKKKMQEEKEQFLEMS
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYENALRKQGISYIAGIDEVGRGPLAGPVVTAAVILPEEFYIPGLNDSKKLSEAKRELFY
HHHHHHHHCCHHHHHCHHHHCCCCCCHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHH
DEIREKAIAIGVGIVSPQVIDEMNIYQATKRAMLDAVANLSYAPEHLLIDAMKLPTSIPQ
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
TSIVKGDAKSISISAASIIAKVTRDRMMKELGKTYPEYGFEKHMGYGTKQHLEAIETYGV
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCHHHHCCCCHHHHHHHHHHHHH
LEEHRKTFAPIKDMIKNKL
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA