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The map label for this gene is tkt [H]

Identifier: 152976060

GI number: 152976060

Start: 2430913

End: 2432913

Strand: Reverse

Name: tkt [H]

Synonym: Bcer98_2336

Alternate gene names: 152976060

Gene position: 2432913-2430913 (Counterclockwise)

Preceding gene: 152976061

Following gene: 152976059

Centisome position: 59.53

GC content: 40.58

Gene sequence:

>2001_bases
ATGTCACATTCAATCGAACAACTTTCTATCAACACGATTCGCACATTATCCATTGATGCGATTGAAAAAGCAAACTCTGG
TCATCCAGGAATGCCAATGGGGGCAGCACCAATGGCTTATACATTATGGACTAAGTTTATGAAACATAATCCAAATAATC
CAACTTGGTTTAACCGCGATCGTTTCGTATTATCTGCAGGTCATGGTTCTATGCTGTTATACAGCTTACTTCATCTATCT
GGTTATGATGTAACAATGGATGATTTAAAGAACTTCCGTCAATGGGGAAGTAAAACACCAGGACATCCAGAATTCGGTCA
TACACCAGGTGTAGACGCAACAACTGGTCCACTTGGACAAGGTATTTCAACTGCTGTTGGGATGGCGATGGCAGAAAGAC
ATTTAGCAGCGAAATATAATCGTGATGCATACAATGTTGTAGATCATTATACATACGCAATTTGCGGTGATGGTGATTTA
ATGGAAGGCGTGTCTGCTGAAGCATCTTCGTTAGCAGCACATTTAGGCTTAGGACGACTAGTTGTATTATATGATTCCAA
TGATATCTCATTAGATGGTGATTTAAATCGTTCATTCTCTGAAAGTGTAGAAGATCGCTATAAAGCATACGGATGGCAAG
TAATCCGCGTTGAGGATGGCAATGATATTGAAGCAATTGCAAACGCAATTGAAAGCGCGAAAGCTGACGAAAAACGCCCA
ACGCTAATTGAAGTAAGAACAACAATTGGTTTCGGTTCTCCAAACAAATCAGGAAAATCAGCTTCGCATGGTTCTCCGCT
TGGTAAAGATGAAACAAAATTAACAAAAGAAGCATACGCTTGGACTGCACAAGAAGATTTCCACGTACCAGCAGAAGTAT
ATGAAAACTTCCGTAAAACAGTGCAAGATGTTGGTGAAAGAGCACAAGCTGAATGGAACACAATGTTCGGTGAATATGCA
AAAGCATACCCAGAATTAGCAAATGAATTACAAATGGCGATGAAAGGTCTGCTTCCAGAAGGCTGGGAACAAAATCTACC
AACTTATGAAGTAGGATCAAAAACAGCAACTCGTTCTTCTTCAGGTGCTGTTATTAATGCAATCGCAGAAGCTGTACCAT
CATTCTTCGGTGGATCTGCAGACCTTGCTGGTTCTAACAAAACATATATGAATAACGAGAAAGATTTTACAAGAGCTGAT
TACAGCGGTAAAAACATTTGGTATGGTGTACGTGAGTTCGCAATGGGTGCAGCAATGAACGGTATCGCACTTCATGGCGG
TTTAAAAACTTACGGTGGTACATTCTTCGTATTCTCTGATTACTTACGCCCAGCAATTCGTCTTGCGGCATTAATGCAAT
TACCTGTGACATATGTATTCACGCATGATAGTATCGCTGTTGGTGAAGATGGTCCAACACATGAACCAATCGAACAATTA
GCAGCTCTTCGTGCGATGCCGAATGTTTCTGTTATCCGTCCAGCTGATGGTAACGAATCTGTAGCGGCTTGGAGATTAGC
TTTAGAATCTACAAAAACACCAACGGCATTAATTTTAACTCGTCAAGACCTTCCTACATTAGAAGGTGCAAAAGAAGATA
CTTATGAGAAAGTGTCAAAAGGTGCATATGTAATTTCTGCAAGCAAGAAAGAAACAGCTGATGTCATCTTACTTGCAACT
GGATCTGAAGTAAGCTTAGCAATTGAAGCGCAAAAAGCGTTGGCGGCAGATGGTATAGATGCATCTGTTGTCAGCATGCC
ATCTATGGATCGCTTTGAAGCACAATCTGCTGAATACAAAGAATCAGTATTACCAAAAGCAGTAACAAAACGTTTCGCAA
TCGAAATGGGTGCTACATTCGGATGGCATCGTTACGTTGGTCTTGAAGGCGACATATTAGGTATCGATATGTTTGGTGCA
TCTGCTCCTGGTGAAAAGATTATGGAAGAGTACGGATTCACTGTAGAAAACGTTGTACGTAAAGTGAAAGAAATGCTTTA
A

Upstream 100 bases:

>100_bases
ACATCAACATATTTGTCGATACATGTTGTATAATCTTGCGTGGGAAGCTATCATATAAATGTATAAAACGTTTACTAATA
TAAGCGAAGGGAAGAATAGC

Downstream 100 bases:

>100_bases
TAGCTTTGAAAAATCTCTCCGATATGGAGAGGTTTTTCTATGTAAATGACTGAATTCGACAGAAAAAGTTTTTTCTTTTT
CCGTAGTCAGACAATCATTG

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 666; Mature: 665

Protein sequence:

>666_residues
MSHSIEQLSINTIRTLSIDAIEKANSGHPGMPMGAAPMAYTLWTKFMKHNPNNPTWFNRDRFVLSAGHGSMLLYSLLHLS
GYDVTMDDLKNFRQWGSKTPGHPEFGHTPGVDATTGPLGQGISTAVGMAMAERHLAAKYNRDAYNVVDHYTYAICGDGDL
MEGVSAEASSLAAHLGLGRLVVLYDSNDISLDGDLNRSFSESVEDRYKAYGWQVIRVEDGNDIEAIANAIESAKADEKRP
TLIEVRTTIGFGSPNKSGKSASHGSPLGKDETKLTKEAYAWTAQEDFHVPAEVYENFRKTVQDVGERAQAEWNTMFGEYA
KAYPELANELQMAMKGLLPEGWEQNLPTYEVGSKTATRSSSGAVINAIAEAVPSFFGGSADLAGSNKTYMNNEKDFTRAD
YSGKNIWYGVREFAMGAAMNGIALHGGLKTYGGTFFVFSDYLRPAIRLAALMQLPVTYVFTHDSIAVGEDGPTHEPIEQL
AALRAMPNVSVIRPADGNESVAAWRLALESTKTPTALILTRQDLPTLEGAKEDTYEKVSKGAYVISASKKETADVILLAT
GSEVSLAIEAQKALAADGIDASVVSMPSMDRFEAQSAEYKESVLPKAVTKRFAIEMGATFGWHRYVGLEGDILGIDMFGA
SAPGEKIMEEYGFTVENVVRKVKEML

Sequences:

>Translated_666_residues
MSHSIEQLSINTIRTLSIDAIEKANSGHPGMPMGAAPMAYTLWTKFMKHNPNNPTWFNRDRFVLSAGHGSMLLYSLLHLS
GYDVTMDDLKNFRQWGSKTPGHPEFGHTPGVDATTGPLGQGISTAVGMAMAERHLAAKYNRDAYNVVDHYTYAICGDGDL
MEGVSAEASSLAAHLGLGRLVVLYDSNDISLDGDLNRSFSESVEDRYKAYGWQVIRVEDGNDIEAIANAIESAKADEKRP
TLIEVRTTIGFGSPNKSGKSASHGSPLGKDETKLTKEAYAWTAQEDFHVPAEVYENFRKTVQDVGERAQAEWNTMFGEYA
KAYPELANELQMAMKGLLPEGWEQNLPTYEVGSKTATRSSSGAVINAIAEAVPSFFGGSADLAGSNKTYMNNEKDFTRAD
YSGKNIWYGVREFAMGAAMNGIALHGGLKTYGGTFFVFSDYLRPAIRLAALMQLPVTYVFTHDSIAVGEDGPTHEPIEQL
AALRAMPNVSVIRPADGNESVAAWRLALESTKTPTALILTRQDLPTLEGAKEDTYEKVSKGAYVISASKKETADVILLAT
GSEVSLAIEAQKALAADGIDASVVSMPSMDRFEAQSAEYKESVLPKAVTKRFAIEMGATFGWHRYVGLEGDILGIDMFGA
SAPGEKIMEEYGFTVENVVRKVKEML
>Mature_665_residues
SHSIEQLSINTIRTLSIDAIEKANSGHPGMPMGAAPMAYTLWTKFMKHNPNNPTWFNRDRFVLSAGHGSMLLYSLLHLSG
YDVTMDDLKNFRQWGSKTPGHPEFGHTPGVDATTGPLGQGISTAVGMAMAERHLAAKYNRDAYNVVDHYTYAICGDGDLM
EGVSAEASSLAAHLGLGRLVVLYDSNDISLDGDLNRSFSESVEDRYKAYGWQVIRVEDGNDIEAIANAIESAKADEKRPT
LIEVRTTIGFGSPNKSGKSASHGSPLGKDETKLTKEAYAWTAQEDFHVPAEVYENFRKTVQDVGERAQAEWNTMFGEYAK
AYPELANELQMAMKGLLPEGWEQNLPTYEVGSKTATRSSSGAVINAIAEAVPSFFGGSADLAGSNKTYMNNEKDFTRADY
SGKNIWYGVREFAMGAAMNGIALHGGLKTYGGTFFVFSDYLRPAIRLAALMQLPVTYVFTHDSIAVGEDGPTHEPIEQLA
ALRAMPNVSVIRPADGNESVAAWRLALESTKTPTALILTRQDLPTLEGAKEDTYEKVSKGAYVISASKKETADVILLATG
SEVSLAIEAQKALAADGIDASVVSMPSMDRFEAQSAEYKESVLPKAVTKRFAIEMGATFGWHRYVGLEGDILGIDMFGAS
APGEKIMEEYGFTVENVVRKVKEML

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=585, Percent_Identity=25.982905982906, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI4507521, Length=585, Percent_Identity=25.982905982906, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI133778974, Length=584, Percent_Identity=26.3698630136986, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI225637459, Length=682, Percent_Identity=21.8475073313783, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI225637463, Length=584, Percent_Identity=22.7739726027397, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI225637461, Length=609, Percent_Identity=22.3316912972085, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI48994911, Length=661, Percent_Identity=51.1346444780635, Blast_Score=676, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=661, Percent_Identity=49.4704992435704, Blast_Score=657, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=671, Percent_Identity=25.1862891207154, Blast_Score=152, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6325331, Length=670, Percent_Identity=50.1492537313433, Blast_Score=644, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319593, Length=671, Percent_Identity=48.5842026825633, Blast_Score=612, Evalue=1e-176,
Organism=Drosophila melanogaster, GI24666278, Length=578, Percent_Identity=27.681660899654, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI45551847, Length=675, Percent_Identity=24.1481481481481, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI45550715, Length=675, Percent_Identity=24.1481481481481, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24645119, Length=647, Percent_Identity=23.8021638330757, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 72445; Mature: 72314

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00037 MYB_1 ; PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2 ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHSIEQLSINTIRTLSIDAIEKANSGHPGMPMGAAPMAYTLWTKFMKHNPNNPTWFNRD
CCCCCHHEECCEEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
RFVLSAGHGSMLLYSLLHLSGYDVTMDDLKNFRQWGSKTPGHPEFGHTPGVDATTGPLGQ
EEEEECCCCHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
GISTAVGMAMAERHLAAKYNRDAYNVVDHYTYAICGDGDLMEGVSAEASSLAAHLGLGRL
CHHHHHHHHHHHHHHHHHCCCCHHHHHHCEEEEEECCCHHHHCCCHHHHHHHHHCCCCEE
VVLYDSNDISLDGDLNRSFSESVEDRYKAYGWQVIRVEDGNDIEAIANAIESAKADEKRP
EEEECCCCEEECCCCCCHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHCCCCCCC
TLIEVRTTIGFGSPNKSGKSASHGSPLGKDETKLTKEAYAWTAQEDFHVPAEVYENFRKT
CEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHEECCCCCCCCCHHHHHHHHHH
VQDVGERAQAEWNTMFGEYAKAYPELANELQMAMKGLLPEGWEQNLPTYEVGSKTATRSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCEECCCCCCCCCC
SGAVINAIAEAVPSFFGGSADLAGSNKTYMNNEKDFTRADYSGKNIWYGVREFAMGAAMN
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
GIALHGGLKTYGGTFFVFSDYLRPAIRLAALMQLPVTYVFTHDSIAVGEDGPTHEPIEQL
CEEEECCHHHCCCEEEEHHHHHHHHHHHHHHHHCCEEEEEECCCEEECCCCCCHHHHHHH
AALRAMPNVSVIRPADGNESVAAWRLALESTKTPTALILTRQDLPTLEGAKEDTYEKVSK
HHHHCCCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHC
GAYVISASKKETADVILLATGSEVSLAIEAQKALAADGIDASVVSMPSMDRFEAQSAEYK
CEEEEECCCCCCCCEEEEEECCCEEEEEEHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHH
ESVLPKAVTKRFAIEMGATFGWHRYVGLEGDILGIDMFGASAPGEKIMEEYGFTVENVVR
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHH
KVKEML
HHHHHC
>Mature Secondary Structure 
SHSIEQLSINTIRTLSIDAIEKANSGHPGMPMGAAPMAYTLWTKFMKHNPNNPTWFNRD
CCCCHHEECCEEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
RFVLSAGHGSMLLYSLLHLSGYDVTMDDLKNFRQWGSKTPGHPEFGHTPGVDATTGPLGQ
EEEEECCCCHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
GISTAVGMAMAERHLAAKYNRDAYNVVDHYTYAICGDGDLMEGVSAEASSLAAHLGLGRL
CHHHHHHHHHHHHHHHHHCCCCHHHHHHCEEEEEECCCHHHHCCCHHHHHHHHHCCCCEE
VVLYDSNDISLDGDLNRSFSESVEDRYKAYGWQVIRVEDGNDIEAIANAIESAKADEKRP
EEEECCCCEEECCCCCCHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHCCCCCCC
TLIEVRTTIGFGSPNKSGKSASHGSPLGKDETKLTKEAYAWTAQEDFHVPAEVYENFRKT
CEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHEECCCCCCCCCHHHHHHHHHH
VQDVGERAQAEWNTMFGEYAKAYPELANELQMAMKGLLPEGWEQNLPTYEVGSKTATRSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCEECCCCCCCCCC
SGAVINAIAEAVPSFFGGSADLAGSNKTYMNNEKDFTRADYSGKNIWYGVREFAMGAAMN
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
GIALHGGLKTYGGTFFVFSDYLRPAIRLAALMQLPVTYVFTHDSIAVGEDGPTHEPIEQL
CEEEECCHHHCCCEEEEHHHHHHHHHHHHHHHHCCEEEEEECCCEEECCCCCCHHHHHHH
AALRAMPNVSVIRPADGNESVAAWRLALESTKTPTALILTRQDLPTLEGAKEDTYEKVSK
HHHHCCCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHC
GAYVISASKKETADVILLATGSEVSLAIEAQKALAADGIDASVVSMPSMDRFEAQSAEYK
CEEEEECCCCCCCCEEEEEECCCEEEEEEHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHH
ESVLPKAVTKRFAIEMGATFGWHRYVGLEGDILGIDMFGASAPGEKIMEEYGFTVENVVR
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHH
KVKEML
HHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]