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The map label for this gene is sirA [H]

Identifier: 152976059

GI number: 152976059

Start: 2430316

End: 2430756

Strand: Reverse

Name: sirA [H]

Synonym: Bcer98_2335

Alternate gene names: 152976059

Gene position: 2430756-2430316 (Counterclockwise)

Preceding gene: 152976060

Following gene: 152976058

Centisome position: 59.47

GC content: 31.75

Gene sequence:

>441_bases
ATGAAAACGTATGAATTGTATTTAATTCAAGAAGATATTGCGAAGACATACTTTGGTCGTGAATCTTTGCTTTTTGATTT
ATTTGTTCGATTTTCAGAATCTGAATCCCTTTCGGAAAAAAAAGTACTATATAAGCAGATGATGTATATTACGATGCCTT
TACAAGTCATAAAAATTCATCATAAATTAGAACAAGCTTTACACCATTTAGGGAAATATAATAGAACATATCATACACAT
ATGCTGTATACAGGGACGGAATACGGAGAAATAATGGTGAAACCACAGTACATTCGAATGAATACCTCTGGAAATGTTTC
AATGGAGACAACTTTTTTTGAGGTGCTCAGAAAATGTGAATTAACATTTTTAGCAATGGATTATGAAAATAAGAAGTATG
GCTGGCTAAATCCTCTCAAGCAAGCACGAACATATGTATAA

Upstream 100 bases:

>100_bases
CGACAGAAAAAGTTTTTTCTTTTTCCGTAGTCAGACAATCATTGCACATATTCTTCTATATAATGTAGAGAAAAAGATTG
TCCAGATCGGGAGGAGAAAA

Downstream 100 bases:

>100_bases
AAAATGTCGAATATCATCTTGTCTTATTGAAAAGGTTTTAGTACACTGTAAGGTAGACAACATGAAGGAGGAAAATATAT
GCCAATTTGGTCAGGTATTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MKTYELYLIQEDIAKTYFGRESLLFDLFVRFSESESLSEKKVLYKQMMYITMPLQVIKIHHKLEQALHHLGKYNRTYHTH
MLYTGTEYGEIMVKPQYIRMNTSGNVSMETTFFEVLRKCELTFLAMDYENKKYGWLNPLKQARTYV

Sequences:

>Translated_146_residues
MKTYELYLIQEDIAKTYFGRESLLFDLFVRFSESESLSEKKVLYKQMMYITMPLQVIKIHHKLEQALHHLGKYNRTYHTH
MLYTGTEYGEIMVKPQYIRMNTSGNVSMETTFFEVLRKCELTFLAMDYENKKYGWLNPLKQARTYV
>Mature_146_residues
MKTYELYLIQEDIAKTYFGRESLLFDLFVRFSESESLSEKKVLYKQMMYITMPLQVIKIHHKLEQALHHLGKYNRTYHTH
MLYTGTEYGEIMVKPQYIRMNTSGNVSMETTFFEVLRKCELTFLAMDYENKKYGWLNPLKQARTYV

Specific function: Inhibits DNA replication in growing cells, thus reducing chromosome copy number and playing a significant role during the onset of sporulation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019683 [H]

Pfam domain/function: PF10747 DUF2522 [H]

EC number: NA

Molecular weight: Translated: 17580; Mature: 17580

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYELYLIQEDIAKTYFGRESLLFDLFVRFSESESLSEKKVLYKQMMYITMPLQVIKIH
CCEEEEEEEHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
HKLEQALHHLGKYNRTYHTHMLYTGTEYGEIMVKPQYIRMNTSGNVSMETTFFEVLRKCE
HHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEECCEEEEECCCCCEEEHHHHHHHHHHCC
LTFLAMDYENKKYGWLNPLKQARTYV
EEEEEEECCCCCCCCCCHHHHHCCCC
>Mature Secondary Structure
MKTYELYLIQEDIAKTYFGRESLLFDLFVRFSESESLSEKKVLYKQMMYITMPLQVIKIH
CCEEEEEEEHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
HKLEQALHHLGKYNRTYHTHMLYTGTEYGEIMVKPQYIRMNTSGNVSMETTFFEVLRKCE
HHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEECCEEEEECCCCCEEEHHHHHHHHHHCC
LTFLAMDYENKKYGWLNPLKQARTYV
EEEEEEECCCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9068642; 8969507; 9384377 [H]