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The map label for this gene is dppE [H]

Identifier: 152975970

GI number: 152975970

Start: 2341232

End: 2342923

Strand: Reverse

Name: dppE [H]

Synonym: Bcer98_2243

Alternate gene names: 152975970

Gene position: 2342923-2341232 (Counterclockwise)

Preceding gene: 152975971

Following gene: 152975969

Centisome position: 57.33

GC content: 34.4

Gene sequence:

>1692_bases
GTGACAAAGAGAAAAATAAAAAAACTAACAGCGGTTGTAGCACCGGTCTTAGCGATGAGCATGGCATTATCAGCATGTTC
TACAGGTGGGGATAAGCAGGCAAGTACAAATTCTAAGGGAGATAGTAAATCAGGTGAGAAGTTAGCGGCAAAGCAAGTAT
TTAACCGTACAGAAAGACAAGAAATTCCAACGATGGATACTTCAAAATCAACTGATACAGTTGGTTCTCAAGTATTAGGG
AATACAATGGAAGGATTATATCGTCTTGATAAAGATAATAAGCCAATTCCAGCAGCAGCAGAATCTAGCACGAAAAGTGA
AGATGGCAAAAAATATACATTTAAACTACGTAAAGAGGCAAAATGGTCAAATGGAGATCCAGTAACAGCGAAAGATTTCG
TCTTTGCATGGCAACGATTATTAGATCCAAGTACAGCTTCGGAGTATGCATTTATTGCATATCCAATCAAAAATGCAGAA
GCGATTAATAAAGGACAAGCAGAGGTATCTACGCTAGGTGTAAAAGCAGTCGATGACTATACACTTGAGGTAGAATTAGA
AAGACCTGTGCCGTACTTTTTAAATTTAACAGCATTTCCATCTTATTATCCGTTAAATGAGAAATTTGTAAAAGAAAAAG
GAGATAAATTCGGATTAGAAGCTGACACGGTTTTATATAACGGACCATTCGTTATGTCTGAATGGAAGCATGAACAAGGT
TGGAAGTTGAAGAAAAATGAAAATTATTGGGATAAAAAAACAGTGAAGCTTGAAGAAATTAACTACAGTGTAGTGAAAGA
ACCAGCAACTTTAGTTAATTTATATGATAGTGGTCAAGTAGATTTTGCGATATTAAAGGGAGAATTTGTAGATAAATACC
GAAACAAAAAAGGTGAATTTGGTGTATATGAACAACCAAATACATTCTTCTTACGATTAAATGAAAAGCGTAATGGTCAA
GATACACCGCTTAAAAATAAAAATTTACGTGAAGCAATCGCGCTTTCTGTCGATAAAAAAGATCTAGTAAACGTTCTTTT
AAATGATGGTTCAAAAGCAGTCGATAGCCTTGTTCCAAAGGGATTAGCGAAAGGTCCAGATGGAAAAGATTTTACAGAAT
CATTTAAAAATGGTTTGAAACACAATACGAAAAAGGCAGCAGCTGCATGGGAAAAAGCGAAAAAAGAGCTTGGCAAAGAT
GAGGTTACAATTGAATTATTAAGCTACGATGACGGGAATGCAAGAAAAGTTGCTGATTATATAAAAGATCAAATTGAGAA
AAATTTAAAAGGTGTAAAAATTAATATTAAAATTCAACCATTTAAACAAAAATTAAAATTAGAATCAGCGCAAGATTATG
AAATCTCATATGCAGGCTGGAGCCCAGACTATTCTGATCCAATGACATACTTAGATATGTTTGAAACAAACAGCTCTTAC
AATCAAATGAGTTATTCAAATCCAAAATATGATGAAATCATTAAACAAGGAAAAACAGAGTTAATGGCAGATGCGAAAAA
ACGTTGGGCAGAATTAGGGAAAGCTGAAAAGCTATTACTTGAAGAAGATGTTGCTCTTGTTCCGCTATTCCAACGTGCTG
ATGCTTATGTAATGAAGCCAAATATAAAAGGTGTTGTTCATCATAACATTAGTCCAGAATTTAGCTTTAAATGGGCTTAT
GTAACGGAATAA

Upstream 100 bases:

>100_bases
GTTAATAGAAATCTTCTGATAAATATAATATAAAGAAAAAAGGAATTTTCAGAAATTTCTCAATCTAGAAACGTACAGGT
AATTGAGGAGGGTATAGAAA

Downstream 100 bases:

>100_bases
AATGAAGCAATAATATAAAGTTTAAAAGCATTTTGAAAGTAGTATTGCTACTTCCAAAATGCTTTTTTGAATAGACTTTC
GTTAAAAATAGTTTTTTATA

Product: extracellular solute-binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 563; Mature: 562

Protein sequence:

>563_residues
MTKRKIKKLTAVVAPVLAMSMALSACSTGGDKQASTNSKGDSKSGEKLAAKQVFNRTERQEIPTMDTSKSTDTVGSQVLG
NTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLRKEAKWSNGDPVTAKDFVFAWQRLLDPSTASEYAFIAYPIKNAE
AINKGQAEVSTLGVKAVDDYTLEVELERPVPYFLNLTAFPSYYPLNEKFVKEKGDKFGLEADTVLYNGPFVMSEWKHEQG
WKLKKNENYWDKKTVKLEEINYSVVKEPATLVNLYDSGQVDFAILKGEFVDKYRNKKGEFGVYEQPNTFFLRLNEKRNGQ
DTPLKNKNLREAIALSVDKKDLVNVLLNDGSKAVDSLVPKGLAKGPDGKDFTESFKNGLKHNTKKAAAAWEKAKKELGKD
EVTIELLSYDDGNARKVADYIKDQIEKNLKGVKINIKIQPFKQKLKLESAQDYEISYAGWSPDYSDPMTYLDMFETNSSY
NQMSYSNPKYDEIIKQGKTELMADAKKRWAELGKAEKLLLEEDVALVPLFQRADAYVMKPNIKGVVHHNISPEFSFKWAY
VTE

Sequences:

>Translated_563_residues
MTKRKIKKLTAVVAPVLAMSMALSACSTGGDKQASTNSKGDSKSGEKLAAKQVFNRTERQEIPTMDTSKSTDTVGSQVLG
NTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLRKEAKWSNGDPVTAKDFVFAWQRLLDPSTASEYAFIAYPIKNAE
AINKGQAEVSTLGVKAVDDYTLEVELERPVPYFLNLTAFPSYYPLNEKFVKEKGDKFGLEADTVLYNGPFVMSEWKHEQG
WKLKKNENYWDKKTVKLEEINYSVVKEPATLVNLYDSGQVDFAILKGEFVDKYRNKKGEFGVYEQPNTFFLRLNEKRNGQ
DTPLKNKNLREAIALSVDKKDLVNVLLNDGSKAVDSLVPKGLAKGPDGKDFTESFKNGLKHNTKKAAAAWEKAKKELGKD
EVTIELLSYDDGNARKVADYIKDQIEKNLKGVKINIKIQPFKQKLKLESAQDYEISYAGWSPDYSDPMTYLDMFETNSSY
NQMSYSNPKYDEIIKQGKTELMADAKKRWAELGKAEKLLLEEDVALVPLFQRADAYVMKPNIKGVVHHNISPEFSFKWAY
VTE
>Mature_562_residues
TKRKIKKLTAVVAPVLAMSMALSACSTGGDKQASTNSKGDSKSGEKLAAKQVFNRTERQEIPTMDTSKSTDTVGSQVLGN
TMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLRKEAKWSNGDPVTAKDFVFAWQRLLDPSTASEYAFIAYPIKNAEA
INKGQAEVSTLGVKAVDDYTLEVELERPVPYFLNLTAFPSYYPLNEKFVKEKGDKFGLEADTVLYNGPFVMSEWKHEQGW
KLKKNENYWDKKTVKLEEINYSVVKEPATLVNLYDSGQVDFAILKGEFVDKYRNKKGEFGVYEQPNTFFLRLNEKRNGQD
TPLKNKNLREAIALSVDKKDLVNVLLNDGSKAVDSLVPKGLAKGPDGKDFTESFKNGLKHNTKKAAAAWEKAKKELGKDE
VTIELLSYDDGNARKVADYIKDQIEKNLKGVKINIKIQPFKQKLKLESAQDYEISYAGWSPDYSDPMTYLDMFETNSSYN
QMSYSNPKYDEIIKQGKTELMADAKKRWAELGKAEKLLLEEDVALVPLFQRADAYVMKPNIKGVVHHNISPEFSFKWAYV
TE

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=552, Percent_Identity=30.0724637681159, Blast_Score=228, Evalue=8e-61,
Organism=Escherichia coli, GI1789397, Length=516, Percent_Identity=28.8759689922481, Blast_Score=225, Evalue=5e-60,
Organism=Escherichia coli, GI87081878, Length=532, Percent_Identity=28.1954887218045, Blast_Score=219, Evalue=5e-58,
Organism=Escherichia coli, GI1787762, Length=461, Percent_Identity=26.6811279826464, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789887, Length=291, Percent_Identity=26.1168384879725, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787052, Length=481, Percent_Identity=22.8690228690229, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1789966, Length=498, Percent_Identity=22.6907630522088, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 63518; Mature: 63386

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRKIKKLTAVVAPVLAMSMALSACSTGGDKQASTNSKGDSKSGEKLAAKQVFNRTERQ
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
EIPTMDTSKSTDTVGSQVLGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLRKEA
HCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCEEEEEEEECC
KWSNGDPVTAKDFVFAWQRLLDPSTASEYAFIAYPIKNAEAINKGQAEVSTLGVKAVDDY
CCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHCCCCHHHHHHCEEEECCE
TLEVELERPVPYFLNLTAFPSYYPLNEKFVKEKGDKFGLEADTVLYNGPFVMSEWKHEQG
EEEEEECCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCCCCCEEEECCCEEECCCCCCCC
WKLKKNENYWDKKTVKLEEINYSVVKEPATLVNLYDSGQVDFAILKGEFVDKYRNKKGEF
CEECCCCCCCCCCEEEEECCCHHHHCCCCCEEEEECCCCEEEEEECCHHHHHHHCCCCCC
GVYEQPNTFFLRLNEKRNGQDTPLKNKNLREAIALSVDKKDLVNVLLNDGSKAVDSLVPK
CCEECCCEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHH
GLAKGPDGKDFTESFKNGLKHNTKKAAAAWEKAKKELGKDEVTIELLSYDDGNARKVADY
HHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHH
IKDQIEKNLKGVKINIKIQPFKQKLKLESAQDYEISYAGWSPDYSDPMTYLDMFETNSSY
HHHHHHCCCCEEEEEEEECCHHHHHCCCCCCCCEEEECCCCCCCCCCHHHHHHHHCCCCC
NQMSYSNPKYDEIIKQGKTELMADAKKRWAELGKAEKLLLEEDVALVPLFQRADAYVMKP
CCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEHHHCCCCEEECC
NIKGVVHHNISPEFSFKWAYVTE
CCCEEEECCCCCCEEEEEEEECC
>Mature Secondary Structure 
TKRKIKKLTAVVAPVLAMSMALSACSTGGDKQASTNSKGDSKSGEKLAAKQVFNRTERQ
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
EIPTMDTSKSTDTVGSQVLGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLRKEA
HCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCEEEEEEEECC
KWSNGDPVTAKDFVFAWQRLLDPSTASEYAFIAYPIKNAEAINKGQAEVSTLGVKAVDDY
CCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHCCCCHHHHHHCEEEECCE
TLEVELERPVPYFLNLTAFPSYYPLNEKFVKEKGDKFGLEADTVLYNGPFVMSEWKHEQG
EEEEEECCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCCCCCEEEECCCEEECCCCCCCC
WKLKKNENYWDKKTVKLEEINYSVVKEPATLVNLYDSGQVDFAILKGEFVDKYRNKKGEF
CEECCCCCCCCCCEEEEECCCHHHHCCCCCEEEEECCCCEEEEEECCHHHHHHHCCCCCC
GVYEQPNTFFLRLNEKRNGQDTPLKNKNLREAIALSVDKKDLVNVLLNDGSKAVDSLVPK
CCEECCCEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHH
GLAKGPDGKDFTESFKNGLKHNTKKAAAAWEKAKKELGKDEVTIELLSYDDGNARKVADY
HHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHH
IKDQIEKNLKGVKINIKIQPFKQKLKLESAQDYEISYAGWSPDYSDPMTYLDMFETNSSY
HHHHHHCCCCEEEEEEEECCHHHHHCCCCCCCCEEEECCCCCCCCCCHHHHHHHHCCCCC
NQMSYSNPKYDEIIKQGKTELMADAKKRWAELGKAEKLLLEEDVALVPLFQRADAYVMKP
CCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEHHHCCCCEEECC
NIKGVVHHNISPEFSFKWAYVTE
CCCEEEECCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]