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The map label for this gene is dppE [H]

Identifier: 152975969

GI number: 152975969

Start: 2339121

End: 2340815

Strand: Reverse

Name: dppE [H]

Synonym: Bcer98_2242

Alternate gene names: 152975969

Gene position: 2340815-2339121 (Counterclockwise)

Preceding gene: 152975970

Following gene: 152975968

Centisome position: 57.27

GC content: 35.22

Gene sequence:

>1695_bases
ATGAAGAAAAAGAAGATGAAAAAGTTAACGACAGTTGCAGCGCCGGTGTTGGCAGTAAGTATGGCGCTGGCCGCATGTTC
TGGATCAGGGGATAAAGAAAAGGCGAATACAACACCGAAAAGTGATGAAAAATCTGGAGGGAAATTAGCGGCAAAGCAAG
TGCTTAATTTAACAGAGCCGCAAGAAATTCCTTCAATGGATTCTTCCAAGGCAACAGACCAAGTATCATTTCTTGTTATG
AATAACGTAATGGAAGGATTATATCGTTTAGGAAAAGATAATAAAGTAACTCCTGGTGTAGCAGAATCCTATAAGAAAAG
CGATGATGGTAAAAAATATACATTTACATTAAATAAAAATGCGAAATGGTCAAACGGAGACCCTGTTACTGCGAAAGATT
TCGTATTTGCTTGGAAGCGTGCTCTAGACCCAAATACAGCTGCTGAATATGCATATATTATGTACGACTTAAAGAATGCA
AAAGCAATTAATGAAGGAAAAGCACCACTTGATACGTTAGGGGTCAAAGCTGTAGATGATTATACATTAGAAGTAGAACT
GGAAAACCCAATTCCATATTTTGTTGAGTTAACATCATTTGGAACATTCTATCCACTTAACGAAAAATTTGTAAAGGAAA
AAGGGGATAAATTTGGTTTAGAAGCAGATACAACGCTTTATAATGGCCCATTTACACTGAGTGAATGGCAACATGAAGAA
GGATGGAAGTTAAAGAAAAATGAGCAATATTGGGATAATAAAACGGTGAAATTAGAAGAAATTAACTTCAATGTCGTCAA
AGAGACTGGTACTCGTGTAAATTTATATGAAAGTGGCCAAATTGATCGTGCAGAAATTTCATCTGAATTTGTAGATAAAT
ATAAATCAAGCCCAGATTTCTTTACAGAAGAAACACCATCAACATTTTTCCTACGTTTAAATCAAAAACGTGGCGGAAAA
GATACAGTGTTTACAAATAAAGATTTACGTTTAGCAATTGCAATGGCATACGATAAAAAAGGATTGACCAATGTGATTTT
AAATGATGGTTCCAAGCCAGCAGACTATTTTGTACCAAAAGAATTTGCGAAAGGCCCAGATGGAAAAGACTTCCGTAAAG
AGAACGGAAATATTTTGAAAACAGATGTGAAGAAAGCGAAAGAACATTGGGAGAAAGCGAAAAAAGAGCTTGGAAAAGAT
AAGGTTACAGTAGAATTACTAAATTATGATACGGAATCGTCAAAAAAAATAGGTGAGTATTTAAAAGGGGAATTAGAGAA
GAACTTACCAGGCTTAACAGTAAATTTAAAAAACCAGCCGTTTAAACAAAAACTAAAGCTAGAAACAGACCAAGATTATG
AGTTATCATTTGCAGGATGGGGCCCTGACTATTTAGATCCAATGACATTTATTGATATGTTTATAACGAACGGAGCACAT
AACCAATCAGGATATTCCAATCCAGAATATGATAAACTTGTAGAACAAGGAAAAGGAGAGTTACTAACAAAGACAAAAGA
ACGCTGGAACGGATTACTGAAAGCTGAGAAAATGTTACTTGAAGATGCGGCAATTGCCCCGTTATTTCAACAGGGTAAAG
GAATTATCCAAAAACAAAAAGTAAAAGGAATTGTTCGCCATCCAGTTGGTGGAGATTATAGTTATAAGTGGGCATATATT
TCTGATGATAAATAA

Upstream 100 bases:

>100_bases
AAGAAGTAGAATATTAATTAATAAGAATTTTCTGATAACAAATAGTTACAGAAGATTTATCAAGGTTAGTATTTTACATA
TAATAGGGGAGGATATAAAA

Downstream 100 bases:

>100_bases
GAATGAGGGGCACGATGATGTGCCCTTTTTTCTATGCACTTTTTTCTTTTGTTCGAATATATAAAATGAAAAAGGAAGAA
TCCTATGAAGCGAAACACCT

Product: extracellular solute-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MKKKKMKKLTTVAAPVLAVSMALAACSGSGDKEKANTTPKSDEKSGGKLAAKQVLNLTEPQEIPSMDSSKATDQVSFLVM
NNVMEGLYRLGKDNKVTPGVAESYKKSDDGKKYTFTLNKNAKWSNGDPVTAKDFVFAWKRALDPNTAAEYAYIMYDLKNA
KAINEGKAPLDTLGVKAVDDYTLEVELENPIPYFVELTSFGTFYPLNEKFVKEKGDKFGLEADTTLYNGPFTLSEWQHEE
GWKLKKNEQYWDNKTVKLEEINFNVVKETGTRVNLYESGQIDRAEISSEFVDKYKSSPDFFTEETPSTFFLRLNQKRGGK
DTVFTNKDLRLAIAMAYDKKGLTNVILNDGSKPADYFVPKEFAKGPDGKDFRKENGNILKTDVKKAKEHWEKAKKELGKD
KVTVELLNYDTESSKKIGEYLKGELEKNLPGLTVNLKNQPFKQKLKLETDQDYELSFAGWGPDYLDPMTFIDMFITNGAH
NQSGYSNPEYDKLVEQGKGELLTKTKERWNGLLKAEKMLLEDAAIAPLFQQGKGIIQKQKVKGIVRHPVGGDYSYKWAYI
SDDK

Sequences:

>Translated_564_residues
MKKKKMKKLTTVAAPVLAVSMALAACSGSGDKEKANTTPKSDEKSGGKLAAKQVLNLTEPQEIPSMDSSKATDQVSFLVM
NNVMEGLYRLGKDNKVTPGVAESYKKSDDGKKYTFTLNKNAKWSNGDPVTAKDFVFAWKRALDPNTAAEYAYIMYDLKNA
KAINEGKAPLDTLGVKAVDDYTLEVELENPIPYFVELTSFGTFYPLNEKFVKEKGDKFGLEADTTLYNGPFTLSEWQHEE
GWKLKKNEQYWDNKTVKLEEINFNVVKETGTRVNLYESGQIDRAEISSEFVDKYKSSPDFFTEETPSTFFLRLNQKRGGK
DTVFTNKDLRLAIAMAYDKKGLTNVILNDGSKPADYFVPKEFAKGPDGKDFRKENGNILKTDVKKAKEHWEKAKKELGKD
KVTVELLNYDTESSKKIGEYLKGELEKNLPGLTVNLKNQPFKQKLKLETDQDYELSFAGWGPDYLDPMTFIDMFITNGAH
NQSGYSNPEYDKLVEQGKGELLTKTKERWNGLLKAEKMLLEDAAIAPLFQQGKGIIQKQKVKGIVRHPVGGDYSYKWAYI
SDDK
>Mature_564_residues
MKKKKMKKLTTVAAPVLAVSMALAACSGSGDKEKANTTPKSDEKSGGKLAAKQVLNLTEPQEIPSMDSSKATDQVSFLVM
NNVMEGLYRLGKDNKVTPGVAESYKKSDDGKKYTFTLNKNAKWSNGDPVTAKDFVFAWKRALDPNTAAEYAYIMYDLKNA
KAINEGKAPLDTLGVKAVDDYTLEVELENPIPYFVELTSFGTFYPLNEKFVKEKGDKFGLEADTTLYNGPFTLSEWQHEE
GWKLKKNEQYWDNKTVKLEEINFNVVKETGTRVNLYESGQIDRAEISSEFVDKYKSSPDFFTEETPSTFFLRLNQKRGGK
DTVFTNKDLRLAIAMAYDKKGLTNVILNDGSKPADYFVPKEFAKGPDGKDFRKENGNILKTDVKKAKEHWEKAKKELGKD
KVTVELLNYDTESSKKIGEYLKGELEKNLPGLTVNLKNQPFKQKLKLETDQDYELSFAGWGPDYLDPMTFIDMFITNGAH
NQSGYSNPEYDKLVEQGKGELLTKTKERWNGLLKAEKMLLEDAAIAPLFQQGKGIIQKQKVKGIVRHPVGGDYSYKWAYI
SDDK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI87081878, Length=506, Percent_Identity=31.8181818181818, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1787495, Length=557, Percent_Identity=30.8797127468582, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1789397, Length=513, Percent_Identity=27.6803118908382, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI1787762, Length=464, Percent_Identity=27.3706896551724, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1789887, Length=513, Percent_Identity=22.8070175438596, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787052, Length=302, Percent_Identity=24.8344370860927, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789966, Length=524, Percent_Identity=22.3282442748092, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 63603; Mature: 63603

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKKMKKLTTVAAPVLAVSMALAACSGSGDKEKANTTPKSDEKSGGKLAAKQVLNLTEP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
QEIPSMDSSKATDQVSFLVMNNVMEGLYRLGKDNKVTPGVAESYKKSDDGKKYTFTLNKN
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCEEEEEECCC
AKWSNGDPVTAKDFVFAWKRALDPNTAAEYAYIMYDLKNAKAINEGKAPLDTLGVKAVDD
CCCCCCCCCCHHHHHHHHHHHCCCCCHHCEEEEEEECCCCCCCCCCCCCHHHHCCEEECC
YTLEVELENPIPYFVELTSFGTFYPLNEKFVKEKGDKFGLEADTTLYNGPFTLSEWQHEE
EEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCCCCCCEEECCCEECCCCCCCC
GWKLKKNEQYWDNKTVKLEEINFNVVKETGTRVNLYESGQIDRAEISSEFVDKYKSSPDF
CCCCCCCCCCCCCCCEEEEECCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCC
FTEETPSTFFLRLNQKRGGKDTVFTNKDLRLAIAMAYDKKGLTNVILNDGSKPADYFVPK
CCCCCCCEEEEEEECCCCCCCCEEECCCCEEEEEEEECCCCCCEEEECCCCCCCCCCCCH
EFAKGPDGKDFRKENGNILKTDVKKAKEHWEKAKKELGKDKVTVELLNYDTESSKKIGEY
HHHCCCCCCCHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHH
LKGELEKNLPGLTVNLKNQPFKQKLKLETDQDYELSFAGWGPDYLDPMTFIDMFITNGAH
HHHHHHHCCCCEEEEECCCCHHHHHCCCCCCCCEEEEECCCCHHCCHHHHHHHHHCCCCC
NQSGYSNPEYDKLVEQGKGELLTKTKERWNGLLKAEKMLLEDAAIAPLFQQGKGIIQKQK
CCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VKGIVRHPVGGDYSYKWAYISDDK
HHHHHCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MKKKKMKKLTTVAAPVLAVSMALAACSGSGDKEKANTTPKSDEKSGGKLAAKQVLNLTEP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCC
QEIPSMDSSKATDQVSFLVMNNVMEGLYRLGKDNKVTPGVAESYKKSDDGKKYTFTLNKN
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCEEEEEECCC
AKWSNGDPVTAKDFVFAWKRALDPNTAAEYAYIMYDLKNAKAINEGKAPLDTLGVKAVDD
CCCCCCCCCCHHHHHHHHHHHCCCCCHHCEEEEEEECCCCCCCCCCCCCHHHHCCEEECC
YTLEVELENPIPYFVELTSFGTFYPLNEKFVKEKGDKFGLEADTTLYNGPFTLSEWQHEE
EEEEEEECCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCCCCCCEEECCCEECCCCCCCC
GWKLKKNEQYWDNKTVKLEEINFNVVKETGTRVNLYESGQIDRAEISSEFVDKYKSSPDF
CCCCCCCCCCCCCCCEEEEECCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCC
FTEETPSTFFLRLNQKRGGKDTVFTNKDLRLAIAMAYDKKGLTNVILNDGSKPADYFVPK
CCCCCCCEEEEEEECCCCCCCCEEECCCCEEEEEEEECCCCCCEEEECCCCCCCCCCCCH
EFAKGPDGKDFRKENGNILKTDVKKAKEHWEKAKKELGKDKVTVELLNYDTESSKKIGEY
HHHCCCCCCCHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHH
LKGELEKNLPGLTVNLKNQPFKQKLKLETDQDYELSFAGWGPDYLDPMTFIDMFITNGAH
HHHHHHHCCCCEEEEECCCCHHHHHCCCCCCCCEEEEECCCCHHCCHHHHHHHHHCCCCC
NQSGYSNPEYDKLVEQGKGELLTKTKERWNGLLKAEKMLLEDAAIAPLFQQGKGIIQKQK
CCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VKGIVRHPVGGDYSYKWAYISDDK
HHHHHCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]