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The map label for this gene is pcp

Identifier: 152975802

GI number: 152975802

Start: 2160226

End: 2160873

Strand: Reverse

Name: pcp

Synonym: Bcer98_2056

Alternate gene names: 152975802

Gene position: 2160873-2160226 (Counterclockwise)

Preceding gene: 152975803

Following gene: 152975801

Centisome position: 52.87

GC content: 38.58

Gene sequence:

>648_bases
ATGAAAACGGTATTGTTAACAGGGTTTGACCCTTTTGGAGGAGAAAAAATCAATCCTGCGTGGGAAGTAGCCAAAGCATT
ACATGAAAAAGAAGGAAATGGATATAAGGTAATTAGCAAACAGATTCCAACAGTATTTCATAAGTCAATCGAACAGCTAG
AGTCATATATAGATGAGTTTAATCCAGAACTAATCATTTGCATTGGACAAGCTGGAGGAAGGGCTGATATAACAGTAGAG
CGTGTTGCAATTAATGTCGATGATGCAAGGATTCCAGATAATGAGAATTATCAACCAATCGATGTTCCAATTATAGAAGA
TGGGCCTGTTGCATATTGGTCGACACTTCCTATAAAGGCGATTGTAAAGAAACTTCGGGAGGAAGGAATACCAGCTTCTG
TATCACAAACTGCTGGTACTTTTGTTTGTAACCACCTTTTCTATGGACTGATGCATCGATTAGCGATAAAGAATAAAAGT
ACGCGCGGTGGCTTTGTACATATTCCATTTCTTCCTGAGCAAGCTAGTCTTCATGCTAATCAGCCAAGCATGTCGCTTTC
TACGATTATAGCGGGTATCCAATTATTAATTGAAGTTGCATTACAAGTGGAAAAAGATATTGTAGAGTGTGGGGGAACTA
CACATTAA

Upstream 100 bases:

>100_bases
AGTCATTAAGGCACAAGCACCGATTGCTATTACTATTTTTGTAATCAATATGTTAATTATGTACGGACTTGTATATCACT
TTTAATAGGGAGTGTTGTAG

Downstream 100 bases:

>100_bases
GACAATGATAACTGGTATAATGTAGAAAGAAATCTACATAGAGGTGAGAGTTATGCAACAATACGAAGAAGTTCGCTCCA
TTCTAGAAAATGCAAAGAAA

Product: pyrrolidone-carboxylate peptidase

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase; Pyroglutamyl-peptidase I; PGP-I; Pyrase

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKTVLLTGFDPFGGEKINPAWEVAKALHEKEGNGYKVISKQIPTVFHKSIEQLESYIDEFNPELIICIGQAGGRADITVE
RVAINVDDARIPDNENYQPIDVPIIEDGPVAYWSTLPIKAIVKKLREEGIPASVSQTAGTFVCNHLFYGLMHRLAIKNKS
TRGGFVHIPFLPEQASLHANQPSMSLSTIIAGIQLLIEVALQVEKDIVECGGTTH

Sequences:

>Translated_215_residues
MKTVLLTGFDPFGGEKINPAWEVAKALHEKEGNGYKVISKQIPTVFHKSIEQLESYIDEFNPELIICIGQAGGRADITVE
RVAINVDDARIPDNENYQPIDVPIIEDGPVAYWSTLPIKAIVKKLREEGIPASVSQTAGTFVCNHLFYGLMHRLAIKNKS
TRGGFVHIPFLPEQASLHANQPSMSLSTIIAGIQLLIEVALQVEKDIVECGGTTH
>Mature_215_residues
MKTVLLTGFDPFGGEKINPAWEVAKALHEKEGNGYKVISKQIPTVFHKSIEQLESYIDEFNPELIICIGQAGGRADITVE
RVAINVDDARIPDNENYQPIDVPIIEDGPVAYWSTLPIKAIVKKLREEGIPASVSQTAGTFVCNHLFYGLMHRLAIKNKS
TRGGFVHIPFLPEQASLHANQPSMSLSTIIAGIQLLIEVALQVEKDIVECGGTTH

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family

Homologues:

Organism=Homo sapiens, GI8923198, Length=213, Percent_Identity=28.6384976525822, Blast_Score=78, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PCP_BACCN (A7GQB6)

Other databases:

- EMBL:   CP000764
- RefSeq:   YP_001375319.1
- ProteinModelPortal:   A7GQB6
- SMR:   A7GQB6
- STRING:   A7GQB6
- MEROPS:   C15.001
- EnsemblBacteria:   EBBACT00000038712
- GeneID:   5344298
- GenomeReviews:   CP000764_GR
- KEGG:   bcy:Bcer98_2056
- eggNOG:   COG2039
- GeneTree:   EBGT00050000001251
- HOGENOM:   HBG360405
- OMA:   NTAGTYV
- ProtClustDB:   PRK13197
- BioCyc:   BCER315749:BCER98_2056-MONOMER
- GO:   GO:0005737
- GO:   GO:0006508
- HAMAP:   MF_00417
- InterPro:   IPR000816
- InterPro:   IPR016125
- Gene3D:   G3DSA:3.40.630.20
- PANTHER:   PTHR23402
- PIRSF:   PIRSF015592
- PRINTS:   PR00706
- TIGRFAMs:   TIGR00504

Pfam domain/function: PF01470 Peptidase_C15; SSF53182 Peptidase_C15-like

EC number: =3.4.19.3

Molecular weight: Translated: 23613; Mature: 23613

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS01334 PYRASE_CYS; PS01333 PYRASE_GLU

Important sites: ACT_SITE 80-80 ACT_SITE 143-143 ACT_SITE 167-167

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVLLTGFDPFGGEKINPAWEVAKALHEKEGNGYKVISKQIPTVFHKSIEQLESYIDEF
CCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHC
NPELIICIGQAGGRADITVERVAINVDDARIPDNENYQPIDVPIIEDGPVAYWSTLPIKA
CCEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCEEEECCCCHHH
IVKKLREEGIPASVSQTAGTFVCNHLFYGLMHRLAIKNKSTRGGFVHIPFLPEQASLHAN
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCC
QPSMSLSTIIAGIQLLIEVALQVEKDIVECGGTTH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKTVLLTGFDPFGGEKINPAWEVAKALHEKEGNGYKVISKQIPTVFHKSIEQLESYIDEF
CCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHC
NPELIICIGQAGGRADITVERVAINVDDARIPDNENYQPIDVPIIEDGPVAYWSTLPIKA
CCEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCEEEECCCCHHH
IVKKLREEGIPASVSQTAGTFVCNHLFYGLMHRLAIKNKSTRGGFVHIPFLPEQASLHAN
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCC
QPSMSLSTIIAGIQLLIEVALQVEKDIVECGGTTH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA