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The map label for this gene is lytF [H]

Identifier: 152975287

GI number: 152975287

Start: 1600923

End: 1602179

Strand: Direct

Name: lytF [H]

Synonym: Bcer98_1493

Alternate gene names: 152975287

Gene position: 1600923-1602179 (Clockwise)

Preceding gene: 152975284

Following gene: 152975288

Centisome position: 39.17

GC content: 39.22

Gene sequence:

>1257_bases
ATGAAGAAAGTAATTGCAGGTTTGGCAGCAGCATCCGTAGCTGGTGTAGCAGTTCCTGGAATGGACTCTGCTCATGCACA
AGTTACATCTGATGCGTTAAAGGAAATCAATGGACAAACTCAACAACAAACAACTAAAACAAACAACGTATCTGAAACAC
CTTCTGAACTAAAATATACAGTAACAGCTGATGTATTGAATGTTCGTTCAGGGGCTGGTACAGAACATAACATTATTTCT
AAAGTAACAGAAGGTCAAGTATTACAAGTAACTGGTGAAGAAAACGGTTGGTTTAAAGTAAATGTAAATGGTAAAGCAGG
CTATGTAAGTGGCGATTTTGTAACAACTGGTGGAACAAAAGGTACTGCTGTTCAACAAGGAACAGGCAACTACACAGTGA
ATGTATCTTCACTTAATGTACGTACAGGCCCAAGTACATCTCATACTGTTTTAGGTTCTGTACATAAAGGAAAAGTGGTA
CAAGTTGTAGGGGAAGTACAAGATTGGTTTAAGGTTAACTACAATGGTGGAACTGGATACATAAGTAAAGACTTCGTAAC
AAAAGGTGGGACAGCTGTATCTAGCCAAACAGAGAAACCAGCTGCAAACAATAGTGTGGCACTTCAAACTGGTGGAGCAT
ATGTAGTAAATACAGGCGCTTTAAAAGTACGTACAGGTCCTGCTACATATAATGCTGTTATTGGTGGTGTAACAAGAGGT
CAAGTGCTACAAGTAACTGGTGTAGAAAATGGTTGGTATAAAATAAATCATAACGGAAGAACAGGGTATGTAAGTGCAGA
CTATGTGAAATTCGTAAAAGGTGGAGCCGCGAATACAAATACAGGTGCAAGTCAAGAAACAACTCAAACACAAAAATCGG
CTGCACCAACAGGTAATACATCATCAGTTGCCGCATTTGCAAGATCTTTAAATGGCTCTCCATATAGAACAGCTGGTACA
ACACCTGCTGGGTTTGACTGCAGTGGCTTTATTTACTATGTATTAAAACAAACAGGGCATAGCGGCCCTCGTCAAACAGT
TGCAGGTTACTGGAGCTCTAAGACAAAAACAAGTAATCCACAACCAGGCGATTTAGTATACTTTGCCAATACTTATAAGG
CTGGTCCTTCACACATGGGTGTTTATTTAGGAAACGGTCAATTCATTAGTGCAGAAACTGATGAAACTGGTGTAAGAATT
AGTTCAGTAAATAACTCTTACTGGAGTAAGCATCTATTAGGGTATACAAAAGCATAA

Upstream 100 bases:

>100_bases
AAAAAATGAAACTTAATGCGCATTCAATTTTAAGAAAATTGTAGATTATTAAGTTCATTTTTTTAAAGAGGGTAGTAGGG
AAAGGAAGTAAAAATAACTT

Downstream 100 bases:

>100_bases
TAAGAGATAGTATCATTATGATAAAAAAGGCTTTCCGAGGAAACTCGGAAGGCTTTTTTCATTTTCAGACTCTAGTAAAA
ACTGTGCGTATAAATCATGA

Product: NLP/P60 protein

Products: NA

Alternate protein names: Cell wall-associated polypeptide CWBP49; Gamma-D-glutamate-meso-diaminopimelate muropeptidase lytF [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MKKVIAGLAAASVAGVAVPGMDSAHAQVTSDALKEINGQTQQQTTKTNNVSETPSELKYTVTADVLNVRSGAGTEHNIIS
KVTEGQVLQVTGEENGWFKVNVNGKAGYVSGDFVTTGGTKGTAVQQGTGNYTVNVSSLNVRTGPSTSHTVLGSVHKGKVV
QVVGEVQDWFKVNYNGGTGYISKDFVTKGGTAVSSQTEKPAANNSVALQTGGAYVVNTGALKVRTGPATYNAVIGGVTRG
QVLQVTGVENGWYKINHNGRTGYVSADYVKFVKGGAANTNTGASQETTQTQKSAAPTGNTSSVAAFARSLNGSPYRTAGT
TPAGFDCSGFIYYVLKQTGHSGPRQTVAGYWSSKTKTSNPQPGDLVYFANTYKAGPSHMGVYLGNGQFISAETDETGVRI
SSVNNSYWSKHLLGYTKA

Sequences:

>Translated_418_residues
MKKVIAGLAAASVAGVAVPGMDSAHAQVTSDALKEINGQTQQQTTKTNNVSETPSELKYTVTADVLNVRSGAGTEHNIIS
KVTEGQVLQVTGEENGWFKVNVNGKAGYVSGDFVTTGGTKGTAVQQGTGNYTVNVSSLNVRTGPSTSHTVLGSVHKGKVV
QVVGEVQDWFKVNYNGGTGYISKDFVTKGGTAVSSQTEKPAANNSVALQTGGAYVVNTGALKVRTGPATYNAVIGGVTRG
QVLQVTGVENGWYKINHNGRTGYVSADYVKFVKGGAANTNTGASQETTQTQKSAAPTGNTSSVAAFARSLNGSPYRTAGT
TPAGFDCSGFIYYVLKQTGHSGPRQTVAGYWSSKTKTSNPQPGDLVYFANTYKAGPSHMGVYLGNGQFISAETDETGVRI
SSVNNSYWSKHLLGYTKA
>Mature_418_residues
MKKVIAGLAAASVAGVAVPGMDSAHAQVTSDALKEINGQTQQQTTKTNNVSETPSELKYTVTADVLNVRSGAGTEHNIIS
KVTEGQVLQVTGEENGWFKVNVNGKAGYVSGDFVTTGGTKGTAVQQGTGNYTVNVSSLNVRTGPSTSHTVLGSVHKGKVV
QVVGEVQDWFKVNYNGGTGYISKDFVTKGGTAVSSQTEKPAANNSVALQTGGAYVVNTGALKVRTGPATYNAVIGGVTRG
QVLQVTGVENGWYKINHNGRTGYVSADYVKFVKGGAANTNTGASQETTQTQKSAAPTGNTSSVAAFARSLNGSPYRTAGT
TPAGFDCSGFIYYVLKQTGHSGPRQTVAGYWSSKTKTSNPQPGDLVYFANTYKAGPSHMGVYLGNGQFISAETDETGVRI
SSVNNSYWSKHLLGYTKA

Specific function: Cleaves gamma-D-glutamate-meso-diaminopimelate bonds. Cell wall hydrolase involved in cell autolysis [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Secreted, cell wall. Note=LysM repeats are thought to be involved in peptidoglycan binding [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 5 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1787944, Length=108, Percent_Identity=36.1111111111111, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786421, Length=109, Percent_Identity=37.6146788990826, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788501, Length=104, Percent_Identity=42.3076923076923, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788001, Length=107, Percent_Identity=36.4485981308411, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60 [H]

EC number: NA

Molecular weight: Translated: 43546; Mature: 43546

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVIAGLAAASVAGVAVPGMDSAHAQVTSDALKEINGQTQQQTTKTNNVSETPSELKYT
CCHHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCEEEE
VTADVLNVRSGAGTEHNIISKVTEGQVLQVTGEENGWFKVNVNGKAGYVSGDFVTTGGTK
EEEEEEEECCCCCCCHHHHHHCCCCEEEEEECCCCCEEEEEECCCEEEEECCEEECCCCC
GTAVQQGTGNYTVNVSSLNVRTGPSTSHTVLGSVHKGKVVQVVGEVQDWFKVNYNGGTGY
CCEEECCCCCEEEEEEEEEEECCCCCCCEEEECCCCCCEEEEEHHCCCEEEEEECCCCCE
ISKDFVTKGGTAVSSQTEKPAANNSVALQTGGAYVVNTGALKVRTGPATYNAVIGGVTRG
EECCCCCCCCCEECCCCCCCCCCCEEEEEECCEEEEECCEEEEEECCCEEEHEECCCCCC
QVLQVTGVENGWYKINHNGRTGYVSADYVKFVKGGAANTNTGASQETTQTQKSAAPTGNT
EEEEEEECCCCCEEEECCCCEEEEEHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCC
SSVAAFARSLNGSPYRTAGTTPAGFDCSGFIYYVLKQTGHSGPRQTVAGYWSSKTKTSNP
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHEEECCCCCCCCCC
QPGDLVYFANTYKAGPSHMGVYLGNGQFISAETDETGVRISSVNNSYWSKHLLGYTKA
CCCCEEEEECCCCCCCCCEEEEECCCEEEECCCCCCCEEEEECCCCHHHHHHCEECCC
>Mature Secondary Structure
MKKVIAGLAAASVAGVAVPGMDSAHAQVTSDALKEINGQTQQQTTKTNNVSETPSELKYT
CCHHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCEEEE
VTADVLNVRSGAGTEHNIISKVTEGQVLQVTGEENGWFKVNVNGKAGYVSGDFVTTGGTK
EEEEEEEECCCCCCCHHHHHHCCCCEEEEEECCCCCEEEEEECCCEEEEECCEEECCCCC
GTAVQQGTGNYTVNVSSLNVRTGPSTSHTVLGSVHKGKVVQVVGEVQDWFKVNYNGGTGY
CCEEECCCCCEEEEEEEEEEECCCCCCCEEEECCCCCCEEEEEHHCCCEEEEEECCCCCE
ISKDFVTKGGTAVSSQTEKPAANNSVALQTGGAYVVNTGALKVRTGPATYNAVIGGVTRG
EECCCCCCCCCEECCCCCCCCCCCEEEEEECCEEEEECCEEEEEECCCEEEHEECCCCCC
QVLQVTGVENGWYKINHNGRTGYVSADYVKFVKGGAANTNTGASQETTQTQKSAAPTGNT
EEEEEEECCCCCEEEECCCCEEEEEHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCC
SSVAAFARSLNGSPYRTAGTTPAGFDCSGFIYYVLKQTGHSGPRQTVAGYWSSKTKTSNP
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHEEECCCCCCCCCC
QPGDLVYFANTYKAGPSHMGVYLGNGQFISAETDETGVRISSVNNSYWSKHLLGYTKA
CCCCEEEEECCCCCCCCCEEEEECCCEEEECCCCCCCEEEEECCCCHHHHHHCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 10206711 [H]