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The map label for this gene is dacA [H]

Identifier: 152975284

GI number: 152975284

Start: 1598380

End: 1599399

Strand: Direct

Name: dacA [H]

Synonym: Bcer98_1490

Alternate gene names: 152975284

Gene position: 1598380-1599399 (Clockwise)

Preceding gene: 152975280

Following gene: 152975287

Centisome position: 39.11

GC content: 34.9

Gene sequence:

>1020_bases
ATGAAAAGGTTAAGGTGGGGAAGAGTAACAATACTATTAGCCGTTATTTTCGGTATATGTTGGTTCGTTTTCCATGAAGG
TTTAGGAAAAGATGATAGAGATATTGCAAAAGCAAAAGAAAATCTTCTAATAGAAGGACAGCCTCTTCAAGTGGCAGAGT
TGCCAAAGTTGGGTGTATCGGAAAAAGTCATTCCGCAAAAATATCTCCCGGTTGTGGAAGCAAAAGCAGCGATTATTATT
GATGCAAGCGATGGAGAAGTAATTTATCAAAATAATGAAAATGAAACGTTTGCTCCAGCGAGTATGTCAAAAATGATGAC
CGCATATTTGCTTTTAGAAAATATACATAAGGGAAAAGTGCATTGGGAAGATCAAGTGAAAATAAGTGCAAAATCAGCAC
AAACGGAAGGTGCTAAAATTCCATTACAAATGAATGATGTAGTAACGGTGAAAGATTTATTCCATGCTTTAATGATTCAA
TCCGCGAATAATGCAGCAGTTGCTTTGGCAGAACATATGGCAAAGACAGAAAAAAACTTTGTTCAAATTATGAATCAAAA
AGCGAAGGATTTGGAACTTTCTAATAAAACGAAGTTTGCTAATGCGTCTGGTCTACAAGAACCAGATGGAAGTGAGACGA
AGATGCCAGCTGCTGATGTTGCAAAGTTGGCGTATCATCTTATTAAAGAGTATCCAGAAATATTAGAGGTAACACATTTA
CGTCGCAGCCAATTAGCTTTTAAAAATATTTCTGTTACAAGCACAAATGAAATGTTAAATACAGCTAATAAAAACCTTCA
TATAGAAGGAATGGATGGATTAAAAACAGGCTTTACTGATAGTGCAGGATATTGTTTCACAGGAACAGCAAAACAGGGAG
ATAAACGTATTATTACAGTTGTTATGGGAACAAAGAGTCAAACAAAACGGTTCACTGAAACACATAAATTAATGTCTTAT
GGATTTGAATTCGTTAATGAGAGAAAAGAACATGAAGAAACATCTTATTTGAAAAAGTGA

Upstream 100 bases:

>100_bases
GTATTAGTATGTTAGGACTTTTTTACCTTGACGGTATGAAGGCATTGTTGATAAGGTTAAATCTGAAATGATAATTTGAT
AGATTAAAAGGAGTTTAGCG

Downstream 100 bases:

>100_bases
ACATCCTCGATTCACTAGAAATACATGAGACAGTCGCTAGTCGGGTAAAAAGAATTTGCAGCGTGAGAAAGGCGTATAAA
AAAGAAGGTCTTCCAATTTT

Product: Serine-type D-Ala-D-Ala carboxypeptidase

Products: NA

Alternate protein names: CPase; DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 5; PBP-5 [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MKRLRWGRVTILLAVIFGICWFVFHEGLGKDDRDIAKAKENLLIEGQPLQVAELPKLGVSEKVIPQKYLPVVEAKAAIII
DASDGEVIYQNNENETFAPASMSKMMTAYLLLENIHKGKVHWEDQVKISAKSAQTEGAKIPLQMNDVVTVKDLFHALMIQ
SANNAAVALAEHMAKTEKNFVQIMNQKAKDLELSNKTKFANASGLQEPDGSETKMPAADVAKLAYHLIKEYPEILEVTHL
RRSQLAFKNISVTSTNEMLNTANKNLHIEGMDGLKTGFTDSAGYCFTGTAKQGDKRIITVVMGTKSQTKRFTETHKLMSY
GFEFVNERKEHEETSYLKK

Sequences:

>Translated_339_residues
MKRLRWGRVTILLAVIFGICWFVFHEGLGKDDRDIAKAKENLLIEGQPLQVAELPKLGVSEKVIPQKYLPVVEAKAAIII
DASDGEVIYQNNENETFAPASMSKMMTAYLLLENIHKGKVHWEDQVKISAKSAQTEGAKIPLQMNDVVTVKDLFHALMIQ
SANNAAVALAEHMAKTEKNFVQIMNQKAKDLELSNKTKFANASGLQEPDGSETKMPAADVAKLAYHLIKEYPEILEVTHL
RRSQLAFKNISVTSTNEMLNTANKNLHIEGMDGLKTGFTDSAGYCFTGTAKQGDKRIITVVMGTKSQTKRFTETHKLMSY
GFEFVNERKEHEETSYLKK
>Mature_339_residues
MKRLRWGRVTILLAVIFGICWFVFHEGLGKDDRDIAKAKENLLIEGQPLQVAELPKLGVSEKVIPQKYLPVVEAKAAIII
DASDGEVIYQNNENETFAPASMSKMMTAYLLLENIHKGKVHWEDQVKISAKSAQTEGAKIPLQMNDVVTVKDLFHALMIQ
SANNAAVALAEHMAKTEKNFVQIMNQKAKDLELSNKTKFANASGLQEPDGSETKMPAADVAKLAYHLIKEYPEILEVTHL
RRSQLAFKNISVTSTNEMLNTANKNLHIEGMDGLKTGFTDSAGYCFTGTAKQGDKRIITVVMGTKSQTKRFTETHKLMSY
GFEFVNERKEHEETSYLKK

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=261, Percent_Identity=35.632183908046, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1786851, Length=262, Percent_Identity=32.0610687022901, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI87082022, Length=263, Percent_Identity=30.4182509505703, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI87082054, Length=258, Percent_Identity=28.6821705426357, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 37934; Mature: 37934

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLRWGRVTILLAVIFGICWFVFHEGLGKDDRDIAKAKENLLIEGQPLQVAELPKLGVS
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCEEECCCCCCHHHCCCCCCC
EKVIPQKYLPVVEAKAAIIIDASDGEVIYQNNENETFAPASMSKMMTAYLLLENIHKGKV
CCCCCHHHCCCEECCEEEEEECCCCEEEEECCCCCEECCHHHHHHHHHHHHHHHHHCCCC
HWEDQVKISAKSAQTEGAKIPLQMNDVVTVKDLFHALMIQSANNAAVALAEHMAKTEKNF
EECCCEEEEECCCCCCCCCCCEECCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VQIMNQKAKDLELSNKTKFANASGLQEPDGSETKMPAADVAKLAYHLIKEYPEILEVTHL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RRSQLAFKNISVTSTNEMLNTANKNLHIEGMDGLKTGFTDSAGYCFTGTAKQGDKRIITV
HHHHHHHHCCEECCHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEECCCCCCCCEEEEE
VMGTKSQTKRFTETHKLMSYGFEFVNERKEHEETSYLKK
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKRLRWGRVTILLAVIFGICWFVFHEGLGKDDRDIAKAKENLLIEGQPLQVAELPKLGVS
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCEEECCCCCCHHHCCCCCCC
EKVIPQKYLPVVEAKAAIIIDASDGEVIYQNNENETFAPASMSKMMTAYLLLENIHKGKV
CCCCCHHHCCCEECCEEEEEECCCCEEEEECCCCCEECCHHHHHHHHHHHHHHHHHCCCC
HWEDQVKISAKSAQTEGAKIPLQMNDVVTVKDLFHALMIQSANNAAVALAEHMAKTEKNF
EECCCEEEEECCCCCCCCCCCEECCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VQIMNQKAKDLELSNKTKFANASGLQEPDGSETKMPAADVAKLAYHLIKEYPEILEVTHL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RRSQLAFKNISVTSTNEMLNTANKNLHIEGMDGLKTGFTDSAGYCFTGTAKQGDKRIITV
HHHHHHHHCCEECCHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEECCCCCCCCEEEEE
VMGTKSQTKRFTETHKLMSYGFEFVNERKEHEETSYLKK
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8370539; 6780559; 111240 [H]