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The map label for this gene is manA [H]

Identifier: 152974973

GI number: 152974973

Start: 1284324

End: 1285268

Strand: Direct

Name: manA [H]

Synonym: Bcer98_1171

Alternate gene names: 152974973

Gene position: 1284324-1285268 (Clockwise)

Preceding gene: 152974972

Following gene: 152974974

Centisome position: 31.42

GC content: 35.24

Gene sequence:

>945_bases
ATGACTGAACCATTATTTTTTGCACCTGTTTTTAAAGAAAGAATTTGGGGGGGAACCCATTTAACTTCTTTTGGATATGA
GATTCCATCAAATCAAACTGGAGAGTGTTGGGCTTTTGCAGCGCATCAACATGGACAAAGTATTGTTAAGAACGGAAAGT
ATAAAGGGTTATCTTTAGGTGAATTGTGGGAAGAACATCGAGATTTATTTGGAAATGTGGAGGGAAAGCGTTTCCCTCTT
CTTACAAAAATTTTGGATGCTAATCAAGGTTTATCTGTTCAAGTTCATCCAAATGATGAGTATGCCAATGTGCATGAAAA
CGGAGAATTGGGAAAGACAGAATGCTGGTATGTAATCGATTCCGAAGAAGACGCAGAAATTATTTATGGACATCATGCAA
AAACAAAAGAAGAATTAGTGACTATGATTAAACAGAAAGAATGGAATCAACTGTTACATCGTGTGAAGGTGAACCCGGGA
GATTTCTTCTATGTGCCAAGCGGAACTGTTCATGCAATTGGTAAAGGAATTTTAATACTAGAAACGCAGCAAAATTCTGA
TACAACCTATAGATTGTATGATTATGATAGAAAAGATTCAGAAGGGAACTTACGTGAACTTCATCTTGAAAAGAGTATTG
AAGTAACTGAAACACCATGTATACAAAAGCAGTTATCGGTGAAACATGAAAAAATAGAAGATTTGAGTGTAACAAACTTT
ATTGAATGTCCGTATTTTTCAGTGGAAAAATGGGAGTTAGATGGATCAGCTAGTTTAAAACAAGAAAAACCCTTCCTTCT
TGTTAGTGTAATCGAGGGGGAAGGGGAATTAATTAAAGAAGGCGAACACTTCTTCTTTAAAAAAGGAGATCATTTTCTAT
TACCTAGCTACTTTGGGGAATACAATTTGAGAGGTAACACTAACTGTATTGTTTCAAGTTTATAA

Upstream 100 bases:

>100_bases
TAATGGATGACAGTTATAGAGAGCGTTTATTATCCGTCCGAACAAAAGAAGAAGCATACAAACTATTAGATGAAATTGTA
TAGAATGGAGGAGTTTAATT

Downstream 100 bases:

>100_bases
TATATTAAGTTAATTATCTATATATAAAATTATAAAATTATTGTTATTAAGTACGGTTCTAGTGCAAAGAATACCTATAT
TTGAAAGAGGTATATAGATT

Product: mannose-6-phosphate isomerase, class I

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MTEPLFFAPVFKERIWGGTHLTSFGYEIPSNQTGECWAFAAHQHGQSIVKNGKYKGLSLGELWEEHRDLFGNVEGKRFPL
LTKILDANQGLSVQVHPNDEYANVHENGELGKTECWYVIDSEEDAEIIYGHHAKTKEELVTMIKQKEWNQLLHRVKVNPG
DFFYVPSGTVHAIGKGILILETQQNSDTTYRLYDYDRKDSEGNLRELHLEKSIEVTETPCIQKQLSVKHEKIEDLSVTNF
IECPYFSVEKWELDGSASLKQEKPFLLVSVIEGEGELIKEGEHFFFKKGDHFLLPSYFGEYNLRGNTNCIVSSL

Sequences:

>Translated_314_residues
MTEPLFFAPVFKERIWGGTHLTSFGYEIPSNQTGECWAFAAHQHGQSIVKNGKYKGLSLGELWEEHRDLFGNVEGKRFPL
LTKILDANQGLSVQVHPNDEYANVHENGELGKTECWYVIDSEEDAEIIYGHHAKTKEELVTMIKQKEWNQLLHRVKVNPG
DFFYVPSGTVHAIGKGILILETQQNSDTTYRLYDYDRKDSEGNLRELHLEKSIEVTETPCIQKQLSVKHEKIEDLSVTNF
IECPYFSVEKWELDGSASLKQEKPFLLVSVIEGEGELIKEGEHFFFKKGDHFLLPSYFGEYNLRGNTNCIVSSL
>Mature_313_residues
TEPLFFAPVFKERIWGGTHLTSFGYEIPSNQTGECWAFAAHQHGQSIVKNGKYKGLSLGELWEEHRDLFGNVEGKRFPLL
TKILDANQGLSVQVHPNDEYANVHENGELGKTECWYVIDSEEDAEIIYGHHAKTKEELVTMIKQKEWNQLLHRVKVNPGD
FFYVPSGTVHAIGKGILILETQQNSDTTYRLYDYDRKDSEGNLRELHLEKSIEVTETPCIQKQLSVKHEKIEDLSVTNFI
ECPYFSVEKWELDGSASLKQEKPFLLVSVIEGEGELIKEGEHFFFKKGDHFLLPSYFGEYNLRGNTNCIVSSL

Specific function: Involved In The Conversion Of Glucose To Gdp-L-Fucose, Which Can Be Converted To L-Fucose, A Capsular Polysaccharide. [C]

COG id: COG1482

COG function: function code G; Phosphomannose isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR001250
- InterPro:   IPR014628
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01238 PMI_typeI [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 35976; Mature: 35845

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPLFFAPVFKERIWGGTHLTSFGYEIPSNQTGECWAFAAHQHGQSIVKNGKYKGLSLG
CCCCEEECHHHHHHHCCCCEEEECCEECCCCCCCCEEEEEEHHCCHHHHHCCCCCCCCHH
ELWEEHRDLFGNVEGKRFPLLTKILDANQGLSVQVHPNDEYANVHENGELGKTECWYVID
HHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEEEE
SEEDAEIIYGHHAKTKEELVTMIKQKEWNQLLHRVKVNPGDFFYVPSGTVHAIGKGILIL
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCCEEECCCCEEEE
ETQQNSDTTYRLYDYDRKDSEGNLRELHLEKSIEVTETPCIQKQLSVKHEKIEDLSVTNF
EECCCCCCEEEEEECCCCCCCCCEEEEEECCCCEECCCCHHHHHHHHHHHHHCCCCCCCE
IECPYFSVEKWELDGSASLKQEKPFLLVSVIEGEGELIKEGEHFFFKKGDHFLLPSYFGE
ECCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCEEECCCEEEEECCCEEECHHHCCC
YNLRGNTNCIVSSL
EECCCCCCEEEECC
>Mature Secondary Structure 
TEPLFFAPVFKERIWGGTHLTSFGYEIPSNQTGECWAFAAHQHGQSIVKNGKYKGLSLG
CCCEEECHHHHHHHCCCCEEEECCEECCCCCCCCEEEEEEHHCCHHHHHCCCCCCCCHH
ELWEEHRDLFGNVEGKRFPLLTKILDANQGLSVQVHPNDEYANVHENGELGKTECWYVID
HHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEEEE
SEEDAEIIYGHHAKTKEELVTMIKQKEWNQLLHRVKVNPGDFFYVPSGTVHAIGKGILIL
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCCEEECCCCEEEE
ETQQNSDTTYRLYDYDRKDSEGNLRELHLEKSIEVTETPCIQKQLSVKHEKIEDLSVTNF
EECCCCCCEEEEEECCCCCCCCCEEEEEECCCCEECCCCHHHHHHHHHHHHHCCCCCCCE
IECPYFSVEKWELDGSASLKQEKPFLLVSVIEGEGELIKEGEHFFFKKGDHFLLPSYFGE
ECCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCEEECCCEEEEECCCEEECHHHCCC
YNLRGNTNCIVSSL
EECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]