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The map label for this gene is manP [H]

Identifier: 152974972

GI number: 152974972

Start: 1282360

End: 1284306

Strand: Direct

Name: manP [H]

Synonym: Bcer98_1170

Alternate gene names: 152974972

Gene position: 1282360-1284306 (Clockwise)

Preceding gene: 152974971

Following gene: 152974973

Centisome position: 31.38

GC content: 37.13

Gene sequence:

>1947_bases
ATGAAACTGTTAGCGATAACATCGTGTCCGAATGGAATTGCCCATACTTATATGGCAGCAGAAAATTTGCAAAAAGCAGC
AGATAAATTAGGGGTTCAAATGAAAATTGAAACCCAAGGTGGTATAGGGGTAGAAAATGAGCTGACTGAACAAGATATTC
GAGAAGCAGACGGGATCATTATAGCTGCTGATAGAGCGGTAAATAAAGATAGATTCATAGGTAAAAAATTATTAGTTGTC
GGAGTTCAAGATGGTATCCGTAAACCAGAGGAATTAATTCAGAAAGTAGCAAGTGGAGATGTACCCGTCTACCATTCACA
ATCGAAAACAGTAGCAAGTAATCAACAGGAAAGAAAGCAAAATCCGATATATCGTCATTTAATGAATGGTGTATCTTTTA
TGGTGCCATTTATTGTAGTTGGTGGATTATTAATTGCAATCGCATTGACGCTCGGTGGAGAAAAAACACCTGGAGGTTTA
GTAATTCCAGAGGGATCTTTCTGGAAAGAAATTGAACAAATTGGCGGTGCATCATTTACATTTATGGTTCCAATATTAGC
TGGATATATTGCATACAGTATAGCTGATAAACCTGGTCTTGTTCCTGGTATGATTGGTGGATATATTGCAGCAACAGGAA
GCTTTTATGGAAGTGAAAGTGGCGCTGGTTTTCTTGGCGGAATTATCGCTGGTTTTCTAGCAGGTTATATAGTATTAGGA
ATTAAAAAAATAAAAGTCCCGAAGGCGATTCAACCTATTATGCCAATCATTATTATTCCAGTGTTTGCTACACTTGTAGT
TGGTTTAGCATTTATATTTATTATAGGTGCTCCTGTCGCACAAGCTTTCGAGTTATTAACTGCTTGGCTGGCGGGTATGC
AAGGATCGAGTTCAATTCTCTTAGCATTGATTTTAGGAGCAATGATTTCATTTGACATGGGTGGTCCAGTCAATAAGGTT
GCATTCTTATTCGGTTCAGCAATGATTGGAGAAGGAAACTATGAAATTATGGGGCCAATTGCTGCAGCAATCTGTATTCC
ACCAATTGGAATGGGACTTGCTACGTTTATAGGAAAGAGAAAGTTTCAAGAGTCAGAAAGAGAAATGGGAAAGGCATCAT
TTACAATGGGACTCTTTGGTATTACTGAAGGAGCTATCCCATTTGCTGCACAAGATCCACTTCGTGTGATTCCAAGTATT
ATGGCTGGTTCAATGACAGGTGCTGTGATTGCGATGATTGGGCATGTAGGTGATAGAGTGGCACATGGTGGTCCAATTGT
TGCAGTGTTAGGAGCAGTAGATAATGTATTTATGTTCTTTGTAGCTGTAATTGTTGGTTCTATTGTGACTGCACTTGTGG
TAAACGTGTTGAAAAAAGATATTTCAAAAGCCGACATGTCAGAAGTAGTAGAAATAAAAGAAGTTTCAGCGACAAAAGAA
ATACCACAGGTACTACAAGAAACAGAAGTAGAAAGCAAACAAGTAGAAATAAAAAAATTAACAGATATTACAAGTTTAGA
GTTAATTGAAACAGATTTAACAGGAGAAACACGAGATGACATCATTGATGAAATGATTCAAAAATTAAACCATATTGGTG
TACTGCATTCAAAAGCAGAATTTAAACAAGCGATTATGAACCGTGAGAACGAAAGTACAACAGGAATTGGTATGAATATT
GCGATTCCACACGGGAAATCAGCTGCTGTTAAGAAACCGAGTGTAGTATTTGGGATTAAACAATCGGGCATAGATTGGAA
AAGCCTTGATGGAACGAAAGCGAAATTAATATTTATGATTGCAGTACCAAAAGAAAGTGAAGGAAATGAACATTTAAAAA
TCCTTCAAATACTTTCTCGGAAACTAATGGATGACAGTTATAGAGAGCGTTTATTATCCGTCCGAACAAAAGAAGAAGCA
TACAAACTATTAGATGAAATTGTATAG

Upstream 100 bases:

>100_bases
ATTTTTCCGGAAGTTCCGGTAAAAAATGAAACTTTTATTATCATAATATTAATTTATATTATATGTAGGCGCTTACAAAG
CAGTGTGAGGAGGACTAAAA

Downstream 100 bases:

>100_bases
AATGGAGGAGTTTAATTATGACTGAACCATTATTTTTTGCACCTGTTTTTAAAGAAAGAATTTGGGGGGGAACCCATTTA
ACTTCTTTTGGATATGAGAT

Product: PTS system, fructose subfamily, IIC subunit

Products: NA

Alternate protein names: EIIBCA-Man; EII-Man; Mannose-specific phosphotransferase enzyme IIB component; PTS system mannose-specific EIIB component; Mannose permease IIC component; PTS system mannose-specific EIIC component; Mannose-specific phosphotransferase enzyme IIA component; PTS system mannose-specific EIIA component [H]

Number of amino acids: Translated: 648; Mature: 648

Protein sequence:

>648_residues
MKLLAITSCPNGIAHTYMAAENLQKAADKLGVQMKIETQGGIGVENELTEQDIREADGIIIAADRAVNKDRFIGKKLLVV
GVQDGIRKPEELIQKVASGDVPVYHSQSKTVASNQQERKQNPIYRHLMNGVSFMVPFIVVGGLLIAIALTLGGEKTPGGL
VIPEGSFWKEIEQIGGASFTFMVPILAGYIAYSIADKPGLVPGMIGGYIAATGSFYGSESGAGFLGGIIAGFLAGYIVLG
IKKIKVPKAIQPIMPIIIIPVFATLVVGLAFIFIIGAPVAQAFELLTAWLAGMQGSSSILLALILGAMISFDMGGPVNKV
AFLFGSAMIGEGNYEIMGPIAAAICIPPIGMGLATFIGKRKFQESEREMGKASFTMGLFGITEGAIPFAAQDPLRVIPSI
MAGSMTGAVIAMIGHVGDRVAHGGPIVAVLGAVDNVFMFFVAVIVGSIVTALVVNVLKKDISKADMSEVVEIKEVSATKE
IPQVLQETEVESKQVEIKKLTDITSLELIETDLTGETRDDIIDEMIQKLNHIGVLHSKAEFKQAIMNRENESTTGIGMNI
AIPHGKSAAVKKPSVVFGIKQSGIDWKSLDGTKAKLIFMIAVPKESEGNEHLKILQILSRKLMDDSYRERLLSVRTKEEA
YKLLDEIV

Sequences:

>Translated_648_residues
MKLLAITSCPNGIAHTYMAAENLQKAADKLGVQMKIETQGGIGVENELTEQDIREADGIIIAADRAVNKDRFIGKKLLVV
GVQDGIRKPEELIQKVASGDVPVYHSQSKTVASNQQERKQNPIYRHLMNGVSFMVPFIVVGGLLIAIALTLGGEKTPGGL
VIPEGSFWKEIEQIGGASFTFMVPILAGYIAYSIADKPGLVPGMIGGYIAATGSFYGSESGAGFLGGIIAGFLAGYIVLG
IKKIKVPKAIQPIMPIIIIPVFATLVVGLAFIFIIGAPVAQAFELLTAWLAGMQGSSSILLALILGAMISFDMGGPVNKV
AFLFGSAMIGEGNYEIMGPIAAAICIPPIGMGLATFIGKRKFQESEREMGKASFTMGLFGITEGAIPFAAQDPLRVIPSI
MAGSMTGAVIAMIGHVGDRVAHGGPIVAVLGAVDNVFMFFVAVIVGSIVTALVVNVLKKDISKADMSEVVEIKEVSATKE
IPQVLQETEVESKQVEIKKLTDITSLELIETDLTGETRDDIIDEMIQKLNHIGVLHSKAEFKQAIMNRENESTTGIGMNI
AIPHGKSAAVKKPSVVFGIKQSGIDWKSLDGTKAKLIFMIAVPKESEGNEHLKILQILSRKLMDDSYRERLLSVRTKEEA
YKLLDEIV
>Mature_648_residues
MKLLAITSCPNGIAHTYMAAENLQKAADKLGVQMKIETQGGIGVENELTEQDIREADGIIIAADRAVNKDRFIGKKLLVV
GVQDGIRKPEELIQKVASGDVPVYHSQSKTVASNQQERKQNPIYRHLMNGVSFMVPFIVVGGLLIAIALTLGGEKTPGGL
VIPEGSFWKEIEQIGGASFTFMVPILAGYIAYSIADKPGLVPGMIGGYIAATGSFYGSESGAGFLGGIIAGFLAGYIVLG
IKKIKVPKAIQPIMPIIIIPVFATLVVGLAFIFIIGAPVAQAFELLTAWLAGMQGSSSILLALILGAMISFDMGGPVNKV
AFLFGSAMIGEGNYEIMGPIAAAICIPPIGMGLATFIGKRKFQESEREMGKASFTMGLFGITEGAIPFAAQDPLRVIPSI
MAGSMTGAVIAMIGHVGDRVAHGGPIVAVLGAVDNVFMFFVAVIVGSIVTALVVNVLKKDISKADMSEVVEIKEVSATKE
IPQVLQETEVESKQVEIKKLTDITSLELIETDLTGETRDDIIDEMIQKLNHIGVLHSKAEFKQAIMNRENESTTGIGMNI
AIPHGKSAAVKKPSVVFGIKQSGIDWKSLDGTKAKLIFMIAVPKESEGNEHLKILQILSRKLMDDSYRERLLSVRTKEEA
YKLLDEIV

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1299

COG function: function code G; Phosphotransferase system, fructose-specific IIC component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788492, Length=464, Percent_Identity=43.1034482758621, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1786951, Length=416, Percent_Identity=40.1442307692308, Blast_Score=268, Evalue=5e-73,
Organism=Escherichia coli, GI87082348, Length=483, Percent_Identity=34.3685300207039, Blast_Score=265, Evalue=1e-71,
Organism=Escherichia coli, GI1790386, Length=304, Percent_Identity=47.6973684210526, Blast_Score=261, Evalue=1e-70,
Organism=Escherichia coli, GI1788729, Length=419, Percent_Identity=27.9236276849642, Blast_Score=116, Evalue=5e-27,
Organism=Escherichia coli, GI1790387, Length=96, Percent_Identity=43.75, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788730, Length=96, Percent_Identity=41.6666666666667, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI2367327, Length=123, Percent_Identity=30.8943089430894, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790390, Length=97, Percent_Identity=39.1752577319588, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 69249; Mature: 69249

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00372 PTS_EIIA_TYPE_2_HIS ; PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2 ; PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLAITSCPNGIAHTYMAAENLQKAADKLGVQMKIETQGGIGVENELTEQDIREADGII
CCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHCCEE
IAADRAVNKDRFIGKKLLVVGVQDGIRKPEELIQKVASGDVPVYHSQSKTVASNQQERKQ
EEECCCCCCHHHCCCEEEEEECHHHCCCHHHHHHHHHCCCCCEEECCCCCHHCCHHHHHC
NPIYRHLMNGVSFMVPFIVVGGLLIAIALTLGGEKTPGGLVIPEGSFWKEIEQIGGASFT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHCCCCHH
FMVPILAGYIAYSIADKPGLVPGMIGGYIAATGSFYGSESGAGFLGGIIAGFLAGYIVLG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IKKIKVPKAIQPIMPIIIIPVFATLVVGLAFIFIIGAPVAQAFELLTAWLAGMQGSSSIL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHH
LALILGAMISFDMGGPVNKVAFLFGSAMIGEGNYEIMGPIAAAICIPPIGMGLATFIGKR
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCHHHHHHHHHHH
KFQESEREMGKASFTMGLFGITEGAIPFAAQDPLRVIPSIMAGSMTGAVIAMIGHVGDRV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHH
AHGGPIVAVLGAVDNVFMFFVAVIVGSIVTALVVNVLKKDISKADMSEVVEIKEVSATKE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPQVLQETEVESKQVEIKKLTDITSLELIETDLTGETRDDIIDEMIQKLNHIGVLHSKAE
HHHHHHHHCCHHHHHHHHHHHCHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHH
FKQAIMNRENESTTGIGMNIAIPHGKSAAVKKPSVVFGIKQSGIDWKSLDGTKAKLIFMI
HHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEE
AVPKESEGNEHLKILQILSRKLMDDSYRERLLSVRTKEEAYKLLDEIV
EECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLLAITSCPNGIAHTYMAAENLQKAADKLGVQMKIETQGGIGVENELTEQDIREADGII
CCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHCCEE
IAADRAVNKDRFIGKKLLVVGVQDGIRKPEELIQKVASGDVPVYHSQSKTVASNQQERKQ
EEECCCCCCHHHCCCEEEEEECHHHCCCHHHHHHHHHCCCCCEEECCCCCHHCCHHHHHC
NPIYRHLMNGVSFMVPFIVVGGLLIAIALTLGGEKTPGGLVIPEGSFWKEIEQIGGASFT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHCCCCHH
FMVPILAGYIAYSIADKPGLVPGMIGGYIAATGSFYGSESGAGFLGGIIAGFLAGYIVLG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IKKIKVPKAIQPIMPIIIIPVFATLVVGLAFIFIIGAPVAQAFELLTAWLAGMQGSSSIL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHH
LALILGAMISFDMGGPVNKVAFLFGSAMIGEGNYEIMGPIAAAICIPPIGMGLATFIGKR
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCHHHHHHHHHHH
KFQESEREMGKASFTMGLFGITEGAIPFAAQDPLRVIPSIMAGSMTGAVIAMIGHVGDRV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHH
AHGGPIVAVLGAVDNVFMFFVAVIVGSIVTALVVNVLKKDISKADMSEVVEIKEVSATKE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPQVLQETEVESKQVEIKKLTDITSLELIETDLTGETRDDIIDEMIQKLNHIGVLHSKAE
HHHHHHHHCCHHHHHHHHHHHCHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHH
FKQAIMNRENESTTGIGMNIAIPHGKSAAVKKPSVVFGIKQSGIDWKSLDGTKAKLIFMI
HHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEE
AVPKESEGNEHLKILQILSRKLMDDSYRERLLSVRTKEEAYKLLDEIV
EECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]