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The map label for this gene is mcpA [H]

Identifier: 152974662

GI number: 152974662

Start: 964136

End: 965857

Strand: Direct

Name: mcpA [H]

Synonym: Bcer98_0849

Alternate gene names: 152974662

Gene position: 964136-965857 (Clockwise)

Preceding gene: 152974661

Following gene: 152974663

Centisome position: 23.59

GC content: 35.77

Gene sequence:

>1722_bases
ATGCGTTTTTTACGAAATTTGAAAGTGAAATATAAGTTATTTTTACTTATTTCATTAGCTGTTCTCGGTTTCATTGTGAT
GAGCTGCGTAGCAATGAACTCGATGAGACAGATGAAACAGAACACAAAGATTGTTGCAGATGATTATCAATATTCTAATG
TCTTGTTGGAAAGTATGCTTCGCACACAAAAGGCATTAGAATATAATTTGCTAACATTAATGACGATTTCACAAAGTGAA
GAGAGGAAAGAGATTGCCAAAGATATTGAAGATGACCTGAAGAAATATGATTCTTTATTGAAAGAATATGATGATGGCTT
TAATTTAAGTAAGCAAGAAGATGAACTGTTTCAAAAGATGAAAAAGGTTGTACCAGATTACAGGAATACATATGAAAGTT
TGTTTGAAAAAGAAAAGTTGATACATGATTCACAACATATAAATGAGTTCCGCGAAGAACTCAAACCAAAAGGTGCTGAG
TTGGCTCGTTATACAGGGGATTTAGAAAAATATGTTGCAGATTTAGTAGATAAAGTATTCGATGATTCTCAAAATATGGT
GGAACAATCTATTACAAGTTTTATCATAACTGTAACTGTTAGTACAATTTTGATCTGTATATTAAGTTATATTATTAGTA
GGTTAATCGTCACGCCTTTACAAACTGTAAGTATTATGATGGGAAGAGTAAAAGAAGGCGATTTAACGGTATATGGAGAT
TATAAAGCGAAAGATGAATTAGGTATATTAGTTAGTGATTTTAATAGTATGATTGAAGGGTTAAGAGAGAATATGAAAGA
AGTTGAAAAGAACATTCAACTATTATCGCAGCACTCTCATGCGGTCGTTTCCGCATCAGAAACGTCGCACCAGGCCGCTA
AACAAATTATAGTAGATATTGAAGAAGTGGCAAGTGGTGCGGATAGTCAAAAGAAAGCGACGGAACAAACTGCGTGTGCA
ATGGAAGAATTGACACAAGAGATACAAGGAATCGTGGATATATCTTCATCTGTAAATGAGTTATCTTCTCAATCTGCATT
AGAAGCGGATAGAGGAAATCAATTTATGAAGCAGATGATTCGACAAATGGATACCATATATGGTTCTGTCCAGCAAGGTG
TGAAACAAGTAGGGAATATGAAAGTCCAATCAGAAGAAATTGTGAAAATTATTGATGTGATACAAGAAATTGCCTCACAG
ATTAATTTATTAGCATTAAATGCGGCGATCGAGGCTGCACGTGCTGGAGAAAGTGGTAGAGGTTTTGCGGTTGTTGCTGA
TGAAGTTAGACAGTTAGCGGAGCAGTCTAGTGAATCGGCAAAACAAATTGAACAACTTGTTGGCCAAGTCATGGAAGTAA
CGAACCATACAGTTGAGATAATGGGGAAAGTAGAAGAGGATGTTCAGCAAGGTACAGAAGTAGCTATGCGTACAGAAGAA
GTATTTGGAAAGATTGCAGAAAAGGTTCAACAAGCATCGTTTCAAATTGAAAGTGCCTCTAGATCTACGGATGAAATGGC
TGCAAGTAGTGAAGAAATTTCTGCTTCAGCAGAAGAAATGGCTCACATTGCCCAAAGATCATCTGACTGTACCGATATGG
TAAAACAATCCATCTTAAAGCAGGAAGAATCAGTCCAAACCATTTCTACTGCAATTGAGCAACTCCATATTATCGCAGGG
GGATTGGAGAAAATTGTTTCTCAATTTACCTTACAAAAATAG

Upstream 100 bases:

>100_bases
TAATTTTTGGTAAAATTTTTCATTGATTTTTCTGCTGATTTTTTCAATAATAAGCTATAAAATTTTAAAAATCTATATAT
AGAGGAGTAAAGTTGTATTT

Downstream 100 bases:

>100_bases
GGGAAACACTCGTCAGTAGAGGGATCATATGAAGAGAGAAAAAGACATGTTAAGTATGTGAAGCTTAATATGTCTTTTAT
TCTATATTTTTACAAATAAT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: H1 [H]

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MRFLRNLKVKYKLFLLISLAVLGFIVMSCVAMNSMRQMKQNTKIVADDYQYSNVLLESMLRTQKALEYNLLTLMTISQSE
ERKEIAKDIEDDLKKYDSLLKEYDDGFNLSKQEDELFQKMKKVVPDYRNTYESLFEKEKLIHDSQHINEFREELKPKGAE
LARYTGDLEKYVADLVDKVFDDSQNMVEQSITSFIITVTVSTILICILSYIISRLIVTPLQTVSIMMGRVKEGDLTVYGD
YKAKDELGILVSDFNSMIEGLRENMKEVEKNIQLLSQHSHAVVSASETSHQAAKQIIVDIEEVASGADSQKKATEQTACA
MEELTQEIQGIVDISSSVNELSSQSALEADRGNQFMKQMIRQMDTIYGSVQQGVKQVGNMKVQSEEIVKIIDVIQEIASQ
INLLALNAAIEAARAGESGRGFAVVADEVRQLAEQSSESAKQIEQLVGQVMEVTNHTVEIMGKVEEDVQQGTEVAMRTEE
VFGKIAEKVQQASFQIESASRSTDEMAASSEEISASAEEMAHIAQRSSDCTDMVKQSILKQEESVQTISTAIEQLHIIAG
GLEKIVSQFTLQK

Sequences:

>Translated_573_residues
MRFLRNLKVKYKLFLLISLAVLGFIVMSCVAMNSMRQMKQNTKIVADDYQYSNVLLESMLRTQKALEYNLLTLMTISQSE
ERKEIAKDIEDDLKKYDSLLKEYDDGFNLSKQEDELFQKMKKVVPDYRNTYESLFEKEKLIHDSQHINEFREELKPKGAE
LARYTGDLEKYVADLVDKVFDDSQNMVEQSITSFIITVTVSTILICILSYIISRLIVTPLQTVSIMMGRVKEGDLTVYGD
YKAKDELGILVSDFNSMIEGLRENMKEVEKNIQLLSQHSHAVVSASETSHQAAKQIIVDIEEVASGADSQKKATEQTACA
MEELTQEIQGIVDISSSVNELSSQSALEADRGNQFMKQMIRQMDTIYGSVQQGVKQVGNMKVQSEEIVKIIDVIQEIASQ
INLLALNAAIEAARAGESGRGFAVVADEVRQLAEQSSESAKQIEQLVGQVMEVTNHTVEIMGKVEEDVQQGTEVAMRTEE
VFGKIAEKVQQASFQIESASRSTDEMAASSEEISASAEEMAHIAQRSSDCTDMVKQSILKQEESVQTISTAIEQLHIIAG
GLEKIVSQFTLQK
>Mature_573_residues
MRFLRNLKVKYKLFLLISLAVLGFIVMSCVAMNSMRQMKQNTKIVADDYQYSNVLLESMLRTQKALEYNLLTLMTISQSE
ERKEIAKDIEDDLKKYDSLLKEYDDGFNLSKQEDELFQKMKKVVPDYRNTYESLFEKEKLIHDSQHINEFREELKPKGAE
LARYTGDLEKYVADLVDKVFDDSQNMVEQSITSFIITVTVSTILICILSYIISRLIVTPLQTVSIMMGRVKEGDLTVYGD
YKAKDELGILVSDFNSMIEGLRENMKEVEKNIQLLSQHSHAVVSASETSHQAAKQIIVDIEEVASGADSQKKATEQTACA
MEELTQEIQGIVDISSSVNELSSQSALEADRGNQFMKQMIRQMDTIYGSVQQGVKQVGNMKVQSEEIVKIIDVIQEIASQ
INLLALNAAIEAARAGESGRGFAVVADEVRQLAEQSSESAKQIEQLVGQVMEVTNHTVEIMGKVEEDVQQGTEVAMRTEE
VFGKIAEKVQQASFQIESASRSTDEMAASSEEISASAEEMAHIAQRSSDCTDMVKQSILKQEESVQTISTAIEQLHIIAG
GLEKIVSQFTLQK

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=360, Percent_Identity=28.8888888888889, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI2367378, Length=526, Percent_Identity=25.4752851711027, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788194, Length=355, Percent_Identity=28.7323943661972, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788195, Length=297, Percent_Identity=27.9461279461279, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1789453, Length=384, Percent_Identity=23.4375, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 64213; Mature: 64213

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLRNLKVKYKLFLLISLAVLGFIVMSCVAMNSMRQMKQNTKIVADDYQYSNVLLESML
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHH
RTQKALEYNLLTLMTISQSEERKEIAKDIEDDLKKYDSLLKEYDDGFNLSKQEDELFQKM
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
KKVVPDYRNTYESLFEKEKLIHDSQHINEFREELKPKGAELARYTGDLEKYVADLVDKVF
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
DDSQNMVEQSITSFIITVTVSTILICILSYIISRLIVTPLQTVSIMMGRVKEGDLTVYGD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
YKAKDELGILVSDFNSMIEGLRENMKEVEKNIQLLSQHSHAVVSASETSHQAAKQIIVDI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCHHHHHHHHHHHHHH
EEVASGADSQKKATEQTACAMEELTQEIQGIVDISSSVNELSSQSALEADRGNQFMKQMI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
RQMDTIYGSVQQGVKQVGNMKVQSEEIVKIIDVIQEIASQINLLALNAAIEAARAGESGR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GFAVVADEVRQLAEQSSESAKQIEQLVGQVMEVTNHTVEIMGKVEEDVQQGTEVAMRTEE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFGKIAEKVQQASFQIESASRSTDEMAASSEEISASAEEMAHIAQRSSDCTDMVKQSILK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QEESVQTISTAIEQLHIIAGGLEKIVSQFTLQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRFLRNLKVKYKLFLLISLAVLGFIVMSCVAMNSMRQMKQNTKIVADDYQYSNVLLESML
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHH
RTQKALEYNLLTLMTISQSEERKEIAKDIEDDLKKYDSLLKEYDDGFNLSKQEDELFQKM
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
KKVVPDYRNTYESLFEKEKLIHDSQHINEFREELKPKGAELARYTGDLEKYVADLVDKVF
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
DDSQNMVEQSITSFIITVTVSTILICILSYIISRLIVTPLQTVSIMMGRVKEGDLTVYGD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
YKAKDELGILVSDFNSMIEGLRENMKEVEKNIQLLSQHSHAVVSASETSHQAAKQIIVDI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCHHHHHHHHHHHHHH
EEVASGADSQKKATEQTACAMEELTQEIQGIVDISSSVNELSSQSALEADRGNQFMKQMI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
RQMDTIYGSVQQGVKQVGNMKVQSEEIVKIIDVIQEIASQINLLALNAAIEAARAGESGR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GFAVVADEVRQLAEQSSESAKQIEQLVGQVMEVTNHTVEIMGKVEEDVQQGTEVAMRTEE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFGKIAEKVQQASFQIESASRSTDEMAASSEEISASAEEMAHIAQRSSDCTDMVKQSILK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QEESVQTISTAIEQLHIIAGGLEKIVSQFTLQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]