Click here to switch to the map view.

The map label for this gene is yhfN [H]

Identifier: 152974661

GI number: 152974661

Start: 962736

End: 963998

Strand: Direct

Name: yhfN [H]

Synonym: Bcer98_0848

Alternate gene names: 152974661

Gene position: 962736-963998 (Clockwise)

Preceding gene: 152974660

Following gene: 152974662

Centisome position: 23.56

GC content: 34.2

Gene sequence:

>1263_bases
GTGAGAAAAGTTATTGGATGGTCGCTTTTTTTGTACGTTGGTTTTGCCTTATTTATATACTGGTATTTATTTGGTTGGAA
CCATGAAATGATTCCAGACATGTATAAAGGCACGAGTGCTGATCCAGCAACCTTTATGAGTGCGAAAGAACTTACATTAA
GCCAAGATTTTTCGAGAGTTAAAAATTTGCTGTTTTTTTTATCTGTGCCTCTTGAATGGATGATTTTATTGCTTGTTCTC
GTTTTAGGGGTATCAAATAAATTTGAGAAATGGTCAAAAGAAACATCGAAGGTAAAAGTCATACAAATTGCGATTTATTT
ATTTTATTTATCATTACTTACAACGGCACTTTCATTACCACTGCAATGGTTCGGGCATCAAGTATCTATTGATTATGGTA
TTTCAACACAAACAACAGCGAGCTGGATACGAGATCACGTTCTTGATTTTTGGATCAACTATGTAATAATGTTTCTGATC
GTTTCCGTTTTATTATGGCTGATGAATAAATTCCCGAAGCGTTGGTGGTTAGCAGGCTGGGCATTATCTGTACCATTTAC
CATCTTTTTAACATTTGTACAGCCTGTTTTAATTGATCCGCTTTATCATGAGTTTTCAACTTTAAAAAATAAAGAGTTAG
AAACGAAAATTTTAACGATTGCAGATCAAGCACATATCCCTGCGGAACATGTATATGAAGTGAATATGTCGGAAAAAACA
AATGCATTAAATGCATACGTGACAGGGATCGGAAAGAATTTTCGCATTGTATTATGGGATACAACGCTTCAGCAACTAAA
AGATAAAGAGATTTTGTTTATTATGGCGCATGAAATAGGACATTATGTCATGAAACATATATATTGGGGCGTAGCCAGTT
ATATTGTTTTAACATTTATCGGCATGTACTTGATTAGTCGCATTTTAAATCTTTGTTTACGAAAATGGGGAGATACATTG
CGAATTTCAAAGCTTGCATGTTTATCCATTCTCCCTTTATTTTTCTTAATTTCCTCTATATTATCTTTTGCCGCAAGTCC
GGCGACAAACTATGTATCTCGCATTGAAGAACGTGCGGCGGATCAATATGCATTACATATGACGAAAGATGGTAAGGCAG
GAGTAAAAACATTCCAATATTTATCCAAAACAAGCCTTAGTCAAGTAAACCCACCTGCTTTAGTAAAATTTTTCTTATAT
ACACATCCACCTATTTTTGAAAGAATTCATACATTTGAAGAATATGAGAGGCAGAAAAAATAA

Upstream 100 bases:

>100_bases
GATTGAAAATTACATGACAATTCCTTAGATTAGCTTGTTCTATTTTGAGAGAAGCGAACTTACAATAATAATAGACAGGC
AGCATAGAGGAGGGAGTACA

Downstream 100 bases:

>100_bases
AGAAGTAGCGGTTTGCTACTTCTTTATTTTTAGTAAATAATTTTTGGTAAAATTTTTCATTGATTTTTCTGCTGATTTTT
TCAATAATAAGCTATAAAAT

Product: peptidase M48 Ste24p

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MRKVIGWSLFLYVGFALFIYWYLFGWNHEMIPDMYKGTSADPATFMSAKELTLSQDFSRVKNLLFFLSVPLEWMILLLVL
VLGVSNKFEKWSKETSKVKVIQIAIYLFYLSLLTTALSLPLQWFGHQVSIDYGISTQTTASWIRDHVLDFWINYVIMFLI
VSVLLWLMNKFPKRWWLAGWALSVPFTIFLTFVQPVLIDPLYHEFSTLKNKELETKILTIADQAHIPAEHVYEVNMSEKT
NALNAYVTGIGKNFRIVLWDTTLQQLKDKEILFIMAHEIGHYVMKHIYWGVASYIVLTFIGMYLISRILNLCLRKWGDTL
RISKLACLSILPLFFLISSILSFAASPATNYVSRIEERAADQYALHMTKDGKAGVKTFQYLSKTSLSQVNPPALVKFFLY
THPPIFERIHTFEEYERQKK

Sequences:

>Translated_420_residues
MRKVIGWSLFLYVGFALFIYWYLFGWNHEMIPDMYKGTSADPATFMSAKELTLSQDFSRVKNLLFFLSVPLEWMILLLVL
VLGVSNKFEKWSKETSKVKVIQIAIYLFYLSLLTTALSLPLQWFGHQVSIDYGISTQTTASWIRDHVLDFWINYVIMFLI
VSVLLWLMNKFPKRWWLAGWALSVPFTIFLTFVQPVLIDPLYHEFSTLKNKELETKILTIADQAHIPAEHVYEVNMSEKT
NALNAYVTGIGKNFRIVLWDTTLQQLKDKEILFIMAHEIGHYVMKHIYWGVASYIVLTFIGMYLISRILNLCLRKWGDTL
RISKLACLSILPLFFLISSILSFAASPATNYVSRIEERAADQYALHMTKDGKAGVKTFQYLSKTSLSQVNPPALVKFFLY
THPPIFERIHTFEEYERQKK
>Mature_420_residues
MRKVIGWSLFLYVGFALFIYWYLFGWNHEMIPDMYKGTSADPATFMSAKELTLSQDFSRVKNLLFFLSVPLEWMILLLVL
VLGVSNKFEKWSKETSKVKVIQIAIYLFYLSLLTTALSLPLQWFGHQVSIDYGISTQTTASWIRDHVLDFWINYVIMFLI
VSVLLWLMNKFPKRWWLAGWALSVPFTIFLTFVQPVLIDPLYHEFSTLKNKELETKILTIADQAHIPAEHVYEVNMSEKT
NALNAYVTGIGKNFRIVLWDTTLQQLKDKEILFIMAHEIGHYVMKHIYWGVASYIVLTFIGMYLISRILNLCLRKWGDTL
RISKLACLSILPLFFLISSILSFAASPATNYVSRIEERAADQYALHMTKDGKAGVKTFQYLSKTSLSQVNPPALVKFFLY
THPPIFERIHTFEEYERQKK

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=389, Percent_Identity=21.5938303341902, Blast_Score=86, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17505484, Length=437, Percent_Identity=21.0526315789474, Blast_Score=86, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6322577, Length=325, Percent_Identity=26.7692307692308, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19922414, Length=210, Percent_Identity=22.8571428571429, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 48905; Mature: 48905

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS00142 ZINC_PROTEASE ; PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKVIGWSLFLYVGFALFIYWYLFGWNHEMIPDMYKGTSADPATFMSAKELTLSQDFSRV
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHH
KNLLFFLSVPLEWMILLLVLVLGVSNKFEKWSKETSKVKVIQIAIYLFYLSLLTTALSLP
HHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LQWFGHQVSIDYGISTQTTASWIRDHVLDFWINYVIMFLIVSVLLWLMNKFPKRWWLAGW
HHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ALSVPFTIFLTFVQPVLIDPLYHEFSTLKNKELETKILTIADQAHIPAEHVYEVNMSEKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEECCCCCCHHHEEECCCCCCC
NALNAYVTGIGKNFRIVLWDTTLQQLKDKEILFIMAHEIGHYVMKHIYWGVASYIVLTFI
HHHHHHHEECCCCCEEEEECCHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
GMYLISRILNLCLRKWGDTLRISKLACLSILPLFFLISSILSFAASPATNYVSRIEERAA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
DQYALHMTKDGKAGVKTFQYLSKTSLSQVNPPALVKFFLYTHPPIFERIHTFEEYERQKK
HHHEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKVIGWSLFLYVGFALFIYWYLFGWNHEMIPDMYKGTSADPATFMSAKELTLSQDFSRV
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHH
KNLLFFLSVPLEWMILLLVLVLGVSNKFEKWSKETSKVKVIQIAIYLFYLSLLTTALSLP
HHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LQWFGHQVSIDYGISTQTTASWIRDHVLDFWINYVIMFLIVSVLLWLMNKFPKRWWLAGW
HHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ALSVPFTIFLTFVQPVLIDPLYHEFSTLKNKELETKILTIADQAHIPAEHVYEVNMSEKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEECCCCCCHHHEEECCCCCCC
NALNAYVTGIGKNFRIVLWDTTLQQLKDKEILFIMAHEIGHYVMKHIYWGVASYIVLTFI
HHHHHHHEECCCCCEEEEECCHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
GMYLISRILNLCLRKWGDTLRISKLACLSILPLFFLISSILSFAASPATNYVSRIEERAA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
DQYALHMTKDGKAGVKTFQYLSKTSLSQVNPPALVKFFLYTHPPIFERIHTFEEYERQKK
HHHEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]