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The map label for this gene is copA [H]

Identifier: 152974349

GI number: 152974349

Start: 592765

End: 595155

Strand: Direct

Name: copA [H]

Synonym: Bcer98_0518

Alternate gene names: 152974349

Gene position: 592765-595155 (Clockwise)

Preceding gene: 152974348

Following gene: 152974350

Centisome position: 14.5

GC content: 38.52

Gene sequence:

>2391_bases
ATGGGGAAAACAAAACAAATAACAATTGGTATTGATGGAATGACATGTTCAGCTTGTTCCGCGCGGATTGAGAAAGTATT
AAATAAGCTAGATGGTGTGGAAGCGAATGTGAATGTAGCAATGGAACAAGCGACGGTTCAATATGATGAAGAGGAACAAA
ATATAGAAGCAATTACAAATCGTATTAAGAAATTAGGATATGAAGTTCGAACGAAAAAAGTAAATTTTGATATTGAAGGT
ATGACATGTGCTGCATGTTCAAATCGAATTGAAAAAGTAATCGGCAAAATGGAAGGAATTGAAACAGTTACCGTTAATTT
AGCTATGAACACTGCAACGATTGTCTATAAAGATGGTCTTCTTACAATAGAAGCGATTCTCGATAAAATAAAGAAATTAG
GCTATAAAGGTAAACTGCAAGAAGACGTTGGATCGACGAAAAAAGAAGAGCAACTAAAAAAGAAAAGAAAACAACTGTTT
CTTTCTATTTTATTGTCACTTCCCCTTCTTTATACGATGGTGGCACATTTGCCGTTTGAAACGGGAATACCAATGCCGCA
TTTTTTAATGAATCCATGGGTGCAATTATTATTTGCAACACCGGTACAATTTTATATTGGTGCACACTTTTATAGCGGTG
CATATCGTGCATTGCGAAATAAAAGTGCAAATATGGATGTACTTGTTGTACTTGGTACATCGGCTGCATATTTTTATAGC
TTATACGAAGGGATCAAAACAATACAGGAACCATCTTATTTACCTCAGCTTTACTTTGAAACAAGTGCGGTGCTAATTAC
ACTAATACTTGTTGGTAAGTATTTCGAGGCGCTTGCAAAAGGAAGAACAACAGAGGCTATTTCAAAATTACTAAGTTTAC
AAGCGAAAGATGCCTTGGTTATTCGTGATGGAAATGAAATATTAATTCCTATAGAAAATGTTGTGATTGGCGATTCAATT
ATAGTGAAACCAGGTGAGAAAATACCTGTGGATGGTATTGTATTATCAGGTATATCCTCAGTTGATGAAGCGATGATTAC
AGGTGAATCTATCCCGGTTGAAAAACAAGTTGGTGATGCTGTAATAGGAGCGACAATCAATAAAAATGGTATTCTCACAA
TGCGTGCTGAAAAAATAGGGAAGGATACTGCCCTTGCAAGTATTATTAAAATCGTTGAAGAAGCTCAAGGGTCAAAAGCA
CCAATTCAGCGCATGGCAGATATCATTTCTGGCATTTTCGTTCCGATAGTAGTTGCGATTGCGATAGTTGCTTTTCTTGT
TTGGTATTTTGCTATTGCTCCTAATGATTTACCACAATCATTAGAAGTCGCCATAGCTGTATTAGTAATTGCTTGTCCTT
GTGCACTTGGTCTTGCTACGCCAACATCAATTATGGTGGGAACTGGAAAAGGCGCAGAGGCAGGTATACTTTTTAAAGGC
GGAGAATATTTAGAAGCGACACATAAAATTAATGCTGTGTTACTAGACAAAACTGGTACTGTTACAAAGGGAAAACCAGA
AGTTACAGATGTATTAAGCTTGCAAGATAATATGCTCGCATTTGCCGCTTCAGCAGAAAATGTTTCAGAACACCCATTAG
CGGCTGCAATTGTTGAGTACGGGAAACAACAAGGAATTACACTCTTACCTGTAGAGGATTTTCGGGCGGCACCTGGACAC
GGTATTGAAGCTAGGATTGAAGCACAGTCCATTGTGATTGGAACGCGAAAATTAATGAATGAGCATGGTGTGAATATAGG
TCAGTTTGAAGAGCACATGGCCGCTCAGGAAGCTGATGGTAAAACTGTTATGCTTGTAGCGATTGAAAATCAATTCGCAG
GAATGATTTCTGTAGCAGATACAATTAAAGAAAGTTCAAAAGAAGCGATTCATGAGATGAAATCTGCTGGAATCGATGTA
TACATGGTAACAGGTGACAATCAGCGAACAGCAGAAGCAATTGCAAAACAGGTAGGAATTGAACATGTGTATGCGGAAGT
GTTACCCGAGAAAAAAGCACGTATTGTGGAGGAATTACAGCATAACGGGAAACAAGTGGCGATGGTTGGTGATGGGATGA
ATGATGCTCCAGCCTTAGCAAAAGCCGATATTGGGATGGCGATTGGAACAGGAACAGATGTAGCAATCGAAGCAGCAGAT
GTTACTCTTGTCGGTGGGAACTTAAAACATATCCCGCAAGCAATTGAGCTAAGTACAAAAACAATGAAAAATATTCGCCA
AAATTTATTCTGGGCTCTGTTTTATAATGCAATTGGTATACCAATTGCGGCAAGCGGTCTGTTAGAGCCTTGGGTAGCTG
GTGCGGCGATGGCATTTAGCTCTGTGTCTGTTGTAACAAATGCTCTTCGTTTGAAACGTGTTAAAATATAA

Upstream 100 bases:

>100_bases
GTATAAAAAAGCTGTTCAAGAAGGAAATGGGGATGTATTTATAAAAGAGTTTTAATGAGAGTCAACAAACAGTTCTCGAA
ATAGAAAGGAGACGAACTGT

Downstream 100 bases:

>100_bases
ATAGAATGGAAACTAAAGTTCTTATTTTTATAAATACAAGAGGATATAGAAGGAGGAAATAAAAATGACTGTAACATTAA
ATGTAAAAGGAATGACATGT

Product: copper-translocating P-type ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 796; Mature: 795

Protein sequence:

>796_residues
MGKTKQITIGIDGMTCSACSARIEKVLNKLDGVEANVNVAMEQATVQYDEEEQNIEAITNRIKKLGYEVRTKKVNFDIEG
MTCAACSNRIEKVIGKMEGIETVTVNLAMNTATIVYKDGLLTIEAILDKIKKLGYKGKLQEDVGSTKKEEQLKKKRKQLF
LSILLSLPLLYTMVAHLPFETGIPMPHFLMNPWVQLLFATPVQFYIGAHFYSGAYRALRNKSANMDVLVVLGTSAAYFYS
LYEGIKTIQEPSYLPQLYFETSAVLITLILVGKYFEALAKGRTTEAISKLLSLQAKDALVIRDGNEILIPIENVVIGDSI
IVKPGEKIPVDGIVLSGISSVDEAMITGESIPVEKQVGDAVIGATINKNGILTMRAEKIGKDTALASIIKIVEEAQGSKA
PIQRMADIISGIFVPIVVAIAIVAFLVWYFAIAPNDLPQSLEVAIAVLVIACPCALGLATPTSIMVGTGKGAEAGILFKG
GEYLEATHKINAVLLDKTGTVTKGKPEVTDVLSLQDNMLAFAASAENVSEHPLAAAIVEYGKQQGITLLPVEDFRAAPGH
GIEARIEAQSIVIGTRKLMNEHGVNIGQFEEHMAAQEADGKTVMLVAIENQFAGMISVADTIKESSKEAIHEMKSAGIDV
YMVTGDNQRTAEAIAKQVGIEHVYAEVLPEKKARIVEELQHNGKQVAMVGDGMNDAPALAKADIGMAIGTGTDVAIEAAD
VTLVGGNLKHIPQAIELSTKTMKNIRQNLFWALFYNAIGIPIAASGLLEPWVAGAAMAFSSVSVVTNALRLKRVKI

Sequences:

>Translated_796_residues
MGKTKQITIGIDGMTCSACSARIEKVLNKLDGVEANVNVAMEQATVQYDEEEQNIEAITNRIKKLGYEVRTKKVNFDIEG
MTCAACSNRIEKVIGKMEGIETVTVNLAMNTATIVYKDGLLTIEAILDKIKKLGYKGKLQEDVGSTKKEEQLKKKRKQLF
LSILLSLPLLYTMVAHLPFETGIPMPHFLMNPWVQLLFATPVQFYIGAHFYSGAYRALRNKSANMDVLVVLGTSAAYFYS
LYEGIKTIQEPSYLPQLYFETSAVLITLILVGKYFEALAKGRTTEAISKLLSLQAKDALVIRDGNEILIPIENVVIGDSI
IVKPGEKIPVDGIVLSGISSVDEAMITGESIPVEKQVGDAVIGATINKNGILTMRAEKIGKDTALASIIKIVEEAQGSKA
PIQRMADIISGIFVPIVVAIAIVAFLVWYFAIAPNDLPQSLEVAIAVLVIACPCALGLATPTSIMVGTGKGAEAGILFKG
GEYLEATHKINAVLLDKTGTVTKGKPEVTDVLSLQDNMLAFAASAENVSEHPLAAAIVEYGKQQGITLLPVEDFRAAPGH
GIEARIEAQSIVIGTRKLMNEHGVNIGQFEEHMAAQEADGKTVMLVAIENQFAGMISVADTIKESSKEAIHEMKSAGIDV
YMVTGDNQRTAEAIAKQVGIEHVYAEVLPEKKARIVEELQHNGKQVAMVGDGMNDAPALAKADIGMAIGTGTDVAIEAAD
VTLVGGNLKHIPQAIELSTKTMKNIRQNLFWALFYNAIGIPIAASGLLEPWVAGAAMAFSSVSVVTNALRLKRVKI
>Mature_795_residues
GKTKQITIGIDGMTCSACSARIEKVLNKLDGVEANVNVAMEQATVQYDEEEQNIEAITNRIKKLGYEVRTKKVNFDIEGM
TCAACSNRIEKVIGKMEGIETVTVNLAMNTATIVYKDGLLTIEAILDKIKKLGYKGKLQEDVGSTKKEEQLKKKRKQLFL
SILLSLPLLYTMVAHLPFETGIPMPHFLMNPWVQLLFATPVQFYIGAHFYSGAYRALRNKSANMDVLVVLGTSAAYFYSL
YEGIKTIQEPSYLPQLYFETSAVLITLILVGKYFEALAKGRTTEAISKLLSLQAKDALVIRDGNEILIPIENVVIGDSII
VKPGEKIPVDGIVLSGISSVDEAMITGESIPVEKQVGDAVIGATINKNGILTMRAEKIGKDTALASIIKIVEEAQGSKAP
IQRMADIISGIFVPIVVAIAIVAFLVWYFAIAPNDLPQSLEVAIAVLVIACPCALGLATPTSIMVGTGKGAEAGILFKGG
EYLEATHKINAVLLDKTGTVTKGKPEVTDVLSLQDNMLAFAASAENVSEHPLAAAIVEYGKQQGITLLPVEDFRAAPGHG
IEARIEAQSIVIGTRKLMNEHGVNIGQFEEHMAAQEADGKTVMLVAIENQFAGMISVADTIKESSKEAIHEMKSAGIDVY
MVTGDNQRTAEAIAKQVGIEHVYAEVLPEKKARIVEELQHNGKQVAMVGDGMNDAPALAKADIGMAIGTGTDVAIEAADV
TLVGGNLKHIPQAIELSTKTMKNIRQNLFWALFYNAIGIPIAASGLLEPWVAGAAMAFSSVSVVTNALRLKRVKI

Specific function: Involved in copper export [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HMA domains [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=861, Percent_Identity=38.9082462253194, Blast_Score=560, Evalue=1e-159,
Organism=Homo sapiens, GI115529486, Length=904, Percent_Identity=38.6061946902655, Blast_Score=557, Evalue=1e-158,
Organism=Homo sapiens, GI55743073, Length=836, Percent_Identity=34.8086124401914, Blast_Score=417, Evalue=1e-116,
Organism=Homo sapiens, GI48762685, Length=170, Percent_Identity=35.8823529411765, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI48762687, Length=170, Percent_Identity=35.8823529411765, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI48762691, Length=163, Percent_Identity=36.8098159509202, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI48762689, Length=163, Percent_Identity=36.8098159509202, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI28373105, Length=176, Percent_Identity=34.0909090909091, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI28373109, Length=167, Percent_Identity=35.3293413173653, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI28373113, Length=176, Percent_Identity=34.0909090909091, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI28373115, Length=167, Percent_Identity=35.3293413173653, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI28373111, Length=167, Percent_Identity=35.3293413173653, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI28373103, Length=176, Percent_Identity=34.0909090909091, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI28373107, Length=167, Percent_Identity=35.3293413173653, Blast_Score=94, Evalue=7e-19,
Organism=Homo sapiens, GI153946397, Length=199, Percent_Identity=32.6633165829146, Blast_Score=93, Evalue=9e-19,
Organism=Homo sapiens, GI10835220, Length=203, Percent_Identity=32.512315270936, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI27886529, Length=203, Percent_Identity=32.512315270936, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI4502271, Length=199, Percent_Identity=32.1608040201005, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI237681111, Length=199, Percent_Identity=32.6633165829146, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI237681109, Length=199, Percent_Identity=32.6633165829146, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI21361181, Length=199, Percent_Identity=32.6633165829146, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI22748667, Length=199, Percent_Identity=32.1608040201005, Blast_Score=91, Evalue=5e-18,
Organism=Homo sapiens, GI209413709, Length=167, Percent_Identity=33.5329341317365, Blast_Score=91, Evalue=5e-18,
Organism=Homo sapiens, GI24638454, Length=167, Percent_Identity=33.5329341317365, Blast_Score=91, Evalue=6e-18,
Organism=Homo sapiens, GI51944966, Length=199, Percent_Identity=31.6582914572864, Blast_Score=91, Evalue=6e-18,
Organism=Homo sapiens, GI4502285, Length=176, Percent_Identity=32.3863636363636, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI118498343, Length=170, Percent_Identity=33.5294117647059, Blast_Score=90, Evalue=9e-18,
Organism=Homo sapiens, GI297374799, Length=199, Percent_Identity=31.6582914572864, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI83700225, Length=199, Percent_Identity=31.6582914572864, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI310128958, Length=159, Percent_Identity=35.8490566037736, Blast_Score=87, Evalue=5e-17,
Organism=Escherichia coli, GI1786691, Length=844, Percent_Identity=36.2559241706161, Blast_Score=487, Evalue=1e-138,
Organism=Escherichia coli, GI1789879, Length=738, Percent_Identity=32.2493224932249, Blast_Score=315, Evalue=9e-87,
Organism=Escherichia coli, GI1786914, Length=520, Percent_Identity=29.8076923076923, Blast_Score=166, Evalue=5e-42,
Organism=Escherichia coli, GI2367363, Length=157, Percent_Identity=30.5732484076433, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17556548, Length=880, Percent_Identity=35.5681818181818, Blast_Score=493, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI32566766, Length=191, Percent_Identity=34.5549738219895, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17557770, Length=191, Percent_Identity=34.5549738219895, Blast_Score=103, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17557486, Length=190, Percent_Identity=34.2105263157895, Blast_Score=103, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71988506, Length=203, Percent_Identity=31.5270935960591, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI193210130, Length=194, Percent_Identity=31.9587628865979, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17554158, Length=194, Percent_Identity=31.9587628865979, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17559224, Length=200, Percent_Identity=32, Blast_Score=93, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71997262, Length=187, Percent_Identity=34.7593582887701, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71997275, Length=187, Percent_Identity=34.7593582887701, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71997269, Length=170, Percent_Identity=35.8823529411765, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI193203354, Length=202, Percent_Identity=29.7029702970297, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193203356, Length=183, Percent_Identity=30.6010928961749, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17541776, Length=195, Percent_Identity=31.7948717948718, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17531459, Length=95, Percent_Identity=43.1578947368421, Blast_Score=76, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI25152707, Length=164, Percent_Identity=34.7560975609756, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71999438, Length=164, Percent_Identity=34.7560975609756, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71999440, Length=164, Percent_Identity=34.7560975609756, Blast_Score=70, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320475, Length=867, Percent_Identity=33.679354094579, Blast_Score=455, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6319772, Length=845, Percent_Identity=28.0473372781065, Blast_Score=305, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6321430, Length=566, Percent_Identity=25.4416961130742, Blast_Score=141, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6325221, Length=566, Percent_Identity=25.2650176678445, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6321271, Length=172, Percent_Identity=36.6279069767442, Blast_Score=98, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6320243, Length=174, Percent_Identity=31.6091954022989, Blast_Score=88, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6320244, Length=174, Percent_Identity=31.6091954022989, Blast_Score=88, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6321432, Length=156, Percent_Identity=33.974358974359, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320245, Length=266, Percent_Identity=27.0676691729323, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI221329854, Length=623, Percent_Identity=37.3996789727127, Blast_Score=357, Evalue=2e-98,
Organism=Drosophila melanogaster, GI17136664, Length=203, Percent_Identity=31.0344827586207, Blast_Score=97, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24762455, Length=167, Percent_Identity=33.5329341317365, Blast_Score=97, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24762453, Length=167, Percent_Identity=33.5329341317365, Blast_Score=97, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24762447, Length=167, Percent_Identity=33.5329341317365, Blast_Score=97, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24762457, Length=167, Percent_Identity=33.5329341317365, Blast_Score=97, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24762449, Length=167, Percent_Identity=33.5329341317365, Blast_Score=97, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24762445, Length=167, Percent_Identity=33.5329341317365, Blast_Score=97, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24762451, Length=167, Percent_Identity=33.5329341317365, Blast_Score=97, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24668704, Length=170, Percent_Identity=37.6470588235294, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24668708, Length=170, Percent_Identity=37.6470588235294, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281366617, Length=170, Percent_Identity=37.6470588235294, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24668696, Length=170, Percent_Identity=37.6470588235294, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI161085803, Length=170, Percent_Identity=37.6470588235294, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281366676, Length=202, Percent_Identity=32.1782178217822, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24648582, Length=204, Percent_Identity=32.3529411764706, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281362164, Length=204, Percent_Identity=32.3529411764706, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI45553441, Length=204, Percent_Identity=32.3529411764706, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24648580, Length=204, Percent_Identity=32.3529411764706, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24648578, Length=204, Percent_Identity=32.3529411764706, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI45553435, Length=204, Percent_Identity=32.3529411764706, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI45553437, Length=204, Percent_Identity=32.3529411764706, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI45553439, Length=204, Percent_Identity=32.3529411764706, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24648576, Length=204, Percent_Identity=32.3529411764706, Blast_Score=91, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 85678; Mature: 85547

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00154 ATPASE_E1_E2 ; PS01047 HMA_1 ; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKTKQITIGIDGMTCSACSARIEKVLNKLDGVEANVNVAMEQATVQYDEEEQNIEAITN
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHEECCCHHHHHHHHHH
RIKKLGYEVRTKKVNFDIEGMTCAACSNRIEKVIGKMEGIETVTVNLAMNTATIVYKDGL
HHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECEEEEEEECCC
LTIEAILDKIKKLGYKGKLQEDVGSTKKEEQLKKKRKQLFLSILLSLPLLYTMVAHLPFE
EEHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TGIPMPHFLMNPWVQLLFATPVQFYIGAHFYSGAYRALRNKSANMDVLVVLGTSAAYFYS
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHH
LYEGIKTIQEPSYLPQLYFETSAVLITLILVGKYFEALAKGRTTEAISKLLSLQAKDALV
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEE
IRDGNEILIPIENVVIGDSIIVKPGEKIPVDGIVLSGISSVDEAMITGESIPVEKQVGDA
EECCCEEEEEECCEEECCEEEECCCCCCCCCCEEECCHHHHHHHHHCCCCCCCHHHHCCE
VIGATINKNGILTMRAEKIGKDTALASIIKIVEEAQGSKAPIQRMADIISGIFVPIVVAI
EEEEEECCCCEEEEEHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
AIVAFLVWYFAIAPNDLPQSLEVAIAVLVIACPCALGLATPTSIMVGTGKGAEAGILFKG
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEC
GEYLEATHKINAVLLDKTGTVTKGKPEVTDVLSLQDNMLAFAASAENVSEHPLAAAIVEY
CCHHHHHCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHH
GKQQGITLLPVEDFRAAPGHGIEARIEAQSIVIGTRKLMNEHGVNIGQFEEHMAAQEADG
HHHCCCEEEEHHHCCCCCCCCCEEEEEHHHEEHHHHHHHHHHCCCCHHHHHHHHHHCCCC
KTVMLVAIENQFAGMISVADTIKESSKEAIHEMKSAGIDVYMVTGDNQRTAEAIAKQVGI
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHH
EHVYAEVLPEKKARIVEELQHNGKQVAMVGDGMNDAPALAKADIGMAIGTGTDVAIEAAD
HHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHCCCCEEECCCCCEEEEEEE
VTLVGGNLKHIPQAIELSTKTMKNIRQNLFWALFYNAIGIPIAASGLLEPWVAGAAMAFS
EEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
SVSVVTNALRLKRVKI
HHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GKTKQITIGIDGMTCSACSARIEKVLNKLDGVEANVNVAMEQATVQYDEEEQNIEAITN
CCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHEECCCHHHHHHHHHH
RIKKLGYEVRTKKVNFDIEGMTCAACSNRIEKVIGKMEGIETVTVNLAMNTATIVYKDGL
HHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECEEEEEEECCC
LTIEAILDKIKKLGYKGKLQEDVGSTKKEEQLKKKRKQLFLSILLSLPLLYTMVAHLPFE
EEHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TGIPMPHFLMNPWVQLLFATPVQFYIGAHFYSGAYRALRNKSANMDVLVVLGTSAAYFYS
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHH
LYEGIKTIQEPSYLPQLYFETSAVLITLILVGKYFEALAKGRTTEAISKLLSLQAKDALV
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEE
IRDGNEILIPIENVVIGDSIIVKPGEKIPVDGIVLSGISSVDEAMITGESIPVEKQVGDA
EECCCEEEEEECCEEECCEEEECCCCCCCCCCEEECCHHHHHHHHHCCCCCCCHHHHCCE
VIGATINKNGILTMRAEKIGKDTALASIIKIVEEAQGSKAPIQRMADIISGIFVPIVVAI
EEEEEECCCCEEEEEHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
AIVAFLVWYFAIAPNDLPQSLEVAIAVLVIACPCALGLATPTSIMVGTGKGAEAGILFKG
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEC
GEYLEATHKINAVLLDKTGTVTKGKPEVTDVLSLQDNMLAFAASAENVSEHPLAAAIVEY
CCHHHHHCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHH
GKQQGITLLPVEDFRAAPGHGIEARIEAQSIVIGTRKLMNEHGVNIGQFEEHMAAQEADG
HHHCCCEEEEHHHCCCCCCCCCEEEEEHHHEEHHHHHHHHHHCCCCHHHHHHHHHHCCCC
KTVMLVAIENQFAGMISVADTIKESSKEAIHEMKSAGIDVYMVTGDNQRTAEAIAKQVGI
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHH
EHVYAEVLPEKKARIVEELQHNGKQVAMVGDGMNDAPALAKADIGMAIGTGTDVAIEAAD
HHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHCCCCEEECCCCCEEEEEEE
VTLVGGNLKHIPQAIELSTKTMKNIRQNLFWALFYNAIGIPIAASGLLEPWVAGAAMAFS
EEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
SVSVVTNALRLKRVKI
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA