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The map label for this gene is exp5 [H]

Identifier: 152974191

GI number: 152974191

Start: 405013

End: 406650

Strand: Direct

Name: exp5 [H]

Synonym: Bcer98_0355

Alternate gene names: 152974191

Gene position: 405013-406650 (Clockwise)

Preceding gene: 152974190

Following gene: 152974192

Centisome position: 9.91

GC content: 36.81

Gene sequence:

>1638_bases
ATGAAAATTACGTCTTTTGATTTTTGGCAGAAGTTTGGGAAAGCGTTGTTAGTTGTTGTAGCAGTTATGCCAGCTGCAGG
TTTAATGATTTCTATTGGTAAGCTAATCGGTATGGCTGCTGGAGATGTAAATGCTGTACATATGATTGCTAGAGTTATGG
AAGACATTGGTTGGGCGATTATTACAAACTTGCATATTTTATTTGCAGTAGCAATTGGGGGATCGTGGGCAAAGGACCGC
GCAGGCGGTGCGTTTGCAGCGCTGTTAGCATTTGTGTTAACAAACCGGATTACGGGAGCTATATTTGGTGTTAACACTGA
AATGTTAGCGGATTCAAAAGCGGAAGTTTCTTCATTATTAGCTGGAGATTTACTTGTAAAAGATTATTTCACTTCTATAC
TTGGTGCACCAGCGCTCAATATGGGAGTATTCGTAGGGATTATTACAGGGTTTTTAGGTGCCACTTTATATAATAAATAT
TATAACTATAATAAATTACCACAGGCATTAGCATTTTTTAATGGGAAACGTTTTGTACCATTTGTTGTAATTGTTTGGTC
TACCATTACGGCAATTGTTTTATCACTTTTATGGCCGTTCATCCAAAGTGGATTAAATGAGTTCGGACGCTGGATTGCGG
CATCGAAAGACAGTGCACCAGTTGTCGCGCCATTCGTATACGGGACATTAGAGCGTCTGTTATTGCCGTTTGGATTACAT
CATATGTTAACGATTCCGATGAACTATACAGAACTTGGTGGGACATATACAATGTTAACGGGTTCGAAAGTTGGTCAAGT
GGTTGCAGGACAAGACCCGCTATGGTTGGCATGGGTTACAGATTTAAATAATTTATTAACAAATGGGGATACAAAAGCAT
ATAACGATTTGTTAAATAATGTAGTGCCAGCTCGTTTTAAAGTAGGACAAGTAATTGGATCGACAGCATCACTAATTGGG
ATTGCATTTGCAATGTTTTACAATGTTGATAAAGACAAACGTGCAAAATATAAGCCGATGTTCTTTTCAGCAGCATTAGC
GGTATTTTTAACAGGTGTTACAGAGCCGATTGAATTTATGTTTATGTTCATCGCTCCATTATTATATATAGTGTATGCAA
TTACAACAGGTCTTGCATTTGCATTGGCAGATCTTATTAATTTACGAGTACATGCATTTGGATTTATTGAATTAATGACT
CGTACACCAATGATGGTTCATGCAGGGTTAACAAGAGACTTAATTCATTTTGTGATTGTTTCAGTAATGTTCTTTATTTT
AAACTTTACCGTATTTCATTTCTTAATTAAAAAGTTTAATTTACCAACTCCAGGGCGTGCGGGTAATTATATTGATAATG
AAGATGATTCTTCAGAACAAATAGCAAATGGAAAAGAAGGGTCTTTAGCAACAAAAGTTATTGACCTTCTAGGTGGAAAG
GATAATATTGCAGATGTAGATGCTTGTATGACACGTTTACGTGTGACAGTGAAAGATTTAAGTGTCGTTGCACCAGAAAC
AGATTGGAAACAAAATGGGGCATTAGGGCTTATTGTAAAAGATAAAGGTGTGCAAGCTGTATACGGTCCAAAAGCAGATG
TATTAAAATCAGATATTCAAGACATGTTAGGTGCATAA

Upstream 100 bases:

>100_bases
ACGTTTGCGTCAATTCTCTGTTTGGAATTGTTTTCATATATGTAGAGAAATTCTATGTTGTCTTATTAGGAAACTGGTAA
ACAAAGGGAGGAAAAAACAG

Downstream 100 bases:

>100_bases
GAAATGAAAGTATTAACTTTAAATTGTCATTCTTGGCAAGAAGAGAATCAATTAGAAAAAATAAAATACCTTGCTAAGAC
GATTCAAGAAGAAAATTACG

Product: PTS system, IIBC subunit

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MKITSFDFWQKFGKALLVVVAVMPAAGLMISIGKLIGMAAGDVNAVHMIARVMEDIGWAIITNLHILFAVAIGGSWAKDR
AGGAFAALLAFVLTNRITGAIFGVNTEMLADSKAEVSSLLAGDLLVKDYFTSILGAPALNMGVFVGIITGFLGATLYNKY
YNYNKLPQALAFFNGKRFVPFVVIVWSTITAIVLSLLWPFIQSGLNEFGRWIAASKDSAPVVAPFVYGTLERLLLPFGLH
HMLTIPMNYTELGGTYTMLTGSKVGQVVAGQDPLWLAWVTDLNNLLTNGDTKAYNDLLNNVVPARFKVGQVIGSTASLIG
IAFAMFYNVDKDKRAKYKPMFFSAALAVFLTGVTEPIEFMFMFIAPLLYIVYAITTGLAFALADLINLRVHAFGFIELMT
RTPMMVHAGLTRDLIHFVIVSVMFFILNFTVFHFLIKKFNLPTPGRAGNYIDNEDDSSEQIANGKEGSLATKVIDLLGGK
DNIADVDACMTRLRVTVKDLSVVAPETDWKQNGALGLIVKDKGVQAVYGPKADVLKSDIQDMLGA

Sequences:

>Translated_545_residues
MKITSFDFWQKFGKALLVVVAVMPAAGLMISIGKLIGMAAGDVNAVHMIARVMEDIGWAIITNLHILFAVAIGGSWAKDR
AGGAFAALLAFVLTNRITGAIFGVNTEMLADSKAEVSSLLAGDLLVKDYFTSILGAPALNMGVFVGIITGFLGATLYNKY
YNYNKLPQALAFFNGKRFVPFVVIVWSTITAIVLSLLWPFIQSGLNEFGRWIAASKDSAPVVAPFVYGTLERLLLPFGLH
HMLTIPMNYTELGGTYTMLTGSKVGQVVAGQDPLWLAWVTDLNNLLTNGDTKAYNDLLNNVVPARFKVGQVIGSTASLIG
IAFAMFYNVDKDKRAKYKPMFFSAALAVFLTGVTEPIEFMFMFIAPLLYIVYAITTGLAFALADLINLRVHAFGFIELMT
RTPMMVHAGLTRDLIHFVIVSVMFFILNFTVFHFLIKKFNLPTPGRAGNYIDNEDDSSEQIANGKEGSLATKVIDLLGGK
DNIADVDACMTRLRVTVKDLSVVAPETDWKQNGALGLIVKDKGVQAVYGPKADVLKSDIQDMLGA
>Mature_545_residues
MKITSFDFWQKFGKALLVVVAVMPAAGLMISIGKLIGMAAGDVNAVHMIARVMEDIGWAIITNLHILFAVAIGGSWAKDR
AGGAFAALLAFVLTNRITGAIFGVNTEMLADSKAEVSSLLAGDLLVKDYFTSILGAPALNMGVFVGIITGFLGATLYNKY
YNYNKLPQALAFFNGKRFVPFVVIVWSTITAIVLSLLWPFIQSGLNEFGRWIAASKDSAPVVAPFVYGTLERLLLPFGLH
HMLTIPMNYTELGGTYTMLTGSKVGQVVAGQDPLWLAWVTDLNNLLTNGDTKAYNDLLNNVVPARFKVGQVIGSTASLIG
IAFAMFYNVDKDKRAKYKPMFFSAALAVFLTGVTEPIEFMFMFIAPLLYIVYAITTGLAFALADLINLRVHAFGFIELMT
RTPMMVHAGLTRDLIHFVIVSVMFFILNFTVFHFLIKKFNLPTPGRAGNYIDNEDDSSEQIANGKEGSLATKVIDLLGGK
DNIADVDACMTRLRVTVKDLSVVAPETDWKQNGALGLIVKDKGVQAVYGPKADVLKSDIQDMLGA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=542, Percent_Identity=33.3948339483395, Blast_Score=258, Evalue=6e-70,
Organism=Escherichia coli, GI1787908, Length=567, Percent_Identity=29.6296296296296, Blast_Score=238, Evalue=9e-64,
Organism=Escherichia coli, GI1786894, Length=535, Percent_Identity=33.4579439252336, Blast_Score=203, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011300 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 59295; Mature: 59295

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITSFDFWQKFGKALLVVVAVMPAAGLMISIGKLIGMAAGDVNAVHMIARVMEDIGWAI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ITNLHILFAVAIGGSWAKDRAGGAFAALLAFVLTNRITGAIFGVNTEMLADSKAEVSSLL
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCHHHHCCCHHHHHHHH
AGDLLVKDYFTSILGAPALNMGVFVGIITGFLGATLYNKYYNYNKLPQALAFFNGKRFVP
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHH
FVVIVWSTITAIVLSLLWPFIQSGLNEFGRWIAASKDSAPVVAPFVYGTLERLLLPFGLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHCCH
HMLTIPMNYTELGGTYTMLTGSKVGQVVAGQDPLWLAWVTDLNNLLTNGDTKAYNDLLNN
HHEECCCCHHHCCCEEEEEECCHHCCCCCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHC
VVPARFKVGQVIGSTASLIGIAFAMFYNVDKDKRAKYKPMFFSAALAVFLTGVTEPIEFM
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHCCCHHHHHH
FMFIAPLLYIVYAITTGLAFALADLINLRVHAFGFIELMTRTPMMVHAGLTRDLIHFVIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHH
SVMFFILNFTVFHFLIKKFNLPTPGRAGNYIDNEDDSSEQIANGKEGSLATKVIDLLGGK
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCC
DNIADVDACMTRLRVTVKDLSVVAPETDWKQNGALGLIVKDKGVQAVYGPKADVLKSDIQ
CCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEEECCCCCEEECCCHHHHHHHHH
DMLGA
HHHCC
>Mature Secondary Structure
MKITSFDFWQKFGKALLVVVAVMPAAGLMISIGKLIGMAAGDVNAVHMIARVMEDIGWAI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ITNLHILFAVAIGGSWAKDRAGGAFAALLAFVLTNRITGAIFGVNTEMLADSKAEVSSLL
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCHHHHCCCHHHHHHHH
AGDLLVKDYFTSILGAPALNMGVFVGIITGFLGATLYNKYYNYNKLPQALAFFNGKRFVP
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHH
FVVIVWSTITAIVLSLLWPFIQSGLNEFGRWIAASKDSAPVVAPFVYGTLERLLLPFGLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHCCH
HMLTIPMNYTELGGTYTMLTGSKVGQVVAGQDPLWLAWVTDLNNLLTNGDTKAYNDLLNN
HHEECCCCHHHCCCEEEEEECCHHCCCCCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHC
VVPARFKVGQVIGSTASLIGIAFAMFYNVDKDKRAKYKPMFFSAALAVFLTGVTEPIEFM
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHHCCCHHHHHH
FMFIAPLLYIVYAITTGLAFALADLINLRVHAFGFIELMTRTPMMVHAGLTRDLIHFVIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHH
SVMFFILNFTVFHFLIKKFNLPTPGRAGNYIDNEDDSSEQIANGKEGSLATKVIDLLGGK
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCC
DNIADVDACMTRLRVTVKDLSVVAPETDWKQNGALGLIVKDKGVQAVYGPKADVLKSDIQ
CCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEEECCCCCEEECCCHHHHHHHHH
DMLGA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11463916; 7934910 [H]