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The map label for this gene is pbuG [H]

Identifier: 152974098

GI number: 152974098

Start: 273250

End: 274575

Strand: Direct

Name: pbuG [H]

Synonym: Bcer98_0254

Alternate gene names: 152974098

Gene position: 273250-274575 (Clockwise)

Preceding gene: 152974097

Following gene: 152974099

Centisome position: 6.69

GC content: 39.52

Gene sequence:

>1326_bases
ATGAAACGTTATTTTCAGTTTGATGAGCTCGGTACAAATTATAAGACTGAGTTCATTGCAGGGTTAACAACATTTTTATC
TATGGCCTACGTACTATTTGTTAATCCTGCCACACTGTCACTTGGAAACATTAAAGGACTACCGGCAGGAACCGGAATGG
ATCCGGGAGCAGTATTCGTTGCCACTGCATTAGCGGCAGCAATCGGTTCTTTAATTATGGGGATTTTTGCAAAATATCCA
ATAGCATTAGCGCCAGGTGTAGGGATTACTTCTTTCTTTGCTTACACAGCGGTATTAACAATGGGAGTTCCATGGCAGAC
AGCAATTGCGGGAACACTCGTATCAGGTATTATCTTCATTATTATTACAGCTCTTGGTATCCGTGAAAAAATTATTAATG
CAATTCCTGCAGAGTTAAAACTTGCGGTAGCAGCAGGTATTGGCTTATTTATCGCCTTTTTGGGTTTTCAAAATGCCGGA
ATTATCGTGAAAAATGATGCGGTTCTTGTTGGATTAGGAGACTTAACAAAGGGCGCAACGTTGTTAGCGATTTTCGGAGT
AGTTGTTACGATTATTTTAATGATTAAAAAGATAAATGGTGCAGTGTTCTATGGGATGATTCTTACAGCTATTCTTGGAA
TGGCAACAGGATTAATTGATACGCCAAAAGCTGTAGTAGGAGCAATTCCAAGTTTAGAACCGACGTTCGGTATGGCGTTA
ACGCACTTTGGAGATATTTTTACTGTTCAAATGGGGATTGTTATTATAACATTCTTCTTTATCGATTTCTTTGATACAGC
AGGTACACTCGTAGCGGTTGTCAATCAAGCGGGTTTAATGAAGGGTAATAAATTACCACGTGCAGGGAAAGCATTATTTG
CAGATGCGATTGCGACTGTAATTGGTGCGATTCTAGGCACTTCTACAACAACTTCCTATATTGAGTCGTCTGCAGGGGTA
GCAGCGGGAGGACGTTCTGGATTTACAGCAGTTGTAACAGCAGGATTCTTCTTACTGGCACTTTTCTTTTCACCGCTATT
AAGTGTTATAACGCCAGCTGTAACGGCGCCAGCTTTAATTATTGTAGGGATTTTAATGGTTTCATCTTTAGGGGAAATTG
AGTGGAAAAAGTTCGAGATTGCTGTACCAGCATTTTTCACAATTATTTCAATGCCACTTACGTATAGTATCGCAACGGGA
ATTGCAATTGGATTCATCTTCTATCCAATTACAATGGTTGTAAGTGGACGACGTAAAGAAGTTCATCCAATTATGTATGT
AATGGGAGTTTTATTCGTACTATATTTCATCTATGTTCGGAAGTAG

Upstream 100 bases:

>100_bases
CTTCCATGTATATAGGCAATGGAAGCCTTTTTTATTTTTTAGGATAAAAGAGGGCTAGGATGAAGTGCGACGAGTCATTA
TACAACGGAGGAAACGTAAG

Downstream 100 bases:

>100_bases
AGGGGTTTTTAAAGGTCTAGACTAAGAGGGGGTCTAGACCTTTTTTTACGTCTTCAGAAAATCTTAAGGATTTCGCACCG
TTTTTCTTTAGAAGTTTTTT

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MKRYFQFDELGTNYKTEFIAGLTTFLSMAYVLFVNPATLSLGNIKGLPAGTGMDPGAVFVATALAAAIGSLIMGIFAKYP
IALAPGVGITSFFAYTAVLTMGVPWQTAIAGTLVSGIIFIIITALGIREKIINAIPAELKLAVAAGIGLFIAFLGFQNAG
IIVKNDAVLVGLGDLTKGATLLAIFGVVVTIILMIKKINGAVFYGMILTAILGMATGLIDTPKAVVGAIPSLEPTFGMAL
THFGDIFTVQMGIVIITFFFIDFFDTAGTLVAVVNQAGLMKGNKLPRAGKALFADAIATVIGAILGTSTTTSYIESSAGV
AAGGRSGFTAVVTAGFFLLALFFSPLLSVITPAVTAPALIIVGILMVSSLGEIEWKKFEIAVPAFFTIISMPLTYSIATG
IAIGFIFYPITMVVSGRRKEVHPIMYVMGVLFVLYFIYVRK

Sequences:

>Translated_441_residues
MKRYFQFDELGTNYKTEFIAGLTTFLSMAYVLFVNPATLSLGNIKGLPAGTGMDPGAVFVATALAAAIGSLIMGIFAKYP
IALAPGVGITSFFAYTAVLTMGVPWQTAIAGTLVSGIIFIIITALGIREKIINAIPAELKLAVAAGIGLFIAFLGFQNAG
IIVKNDAVLVGLGDLTKGATLLAIFGVVVTIILMIKKINGAVFYGMILTAILGMATGLIDTPKAVVGAIPSLEPTFGMAL
THFGDIFTVQMGIVIITFFFIDFFDTAGTLVAVVNQAGLMKGNKLPRAGKALFADAIATVIGAILGTSTTTSYIESSAGV
AAGGRSGFTAVVTAGFFLLALFFSPLLSVITPAVTAPALIIVGILMVSSLGEIEWKKFEIAVPAFFTIISMPLTYSIATG
IAIGFIFYPITMVVSGRRKEVHPIMYVMGVLFVLYFIYVRK
>Mature_441_residues
MKRYFQFDELGTNYKTEFIAGLTTFLSMAYVLFVNPATLSLGNIKGLPAGTGMDPGAVFVATALAAAIGSLIMGIFAKYP
IALAPGVGITSFFAYTAVLTMGVPWQTAIAGTLVSGIIFIIITALGIREKIINAIPAELKLAVAAGIGLFIAFLGFQNAG
IIVKNDAVLVGLGDLTKGATLLAIFGVVVTIILMIKKINGAVFYGMILTAILGMATGLIDTPKAVVGAIPSLEPTFGMAL
THFGDIFTVQMGIVIITFFFIDFFDTAGTLVAVVNQAGLMKGNKLPRAGKALFADAIATVIGAILGTSTTTSYIESSAGV
AAGGRSGFTAVVTAGFFLLALFFSPLLSVITPAVTAPALIIVGILMVSSLGEIEWKKFEIAVPAFFTIISMPLTYSIATG
IAIGFIFYPITMVVSGRRKEVHPIMYVMGVLFVLYFIYVRK

Specific function: Involved in the uptake of the purine bases hypoxanthine and guanine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=447, Percent_Identity=40.7158836689038, Blast_Score=333, Evalue=1e-92,
Organism=Escherichia coli, GI1790150, Length=440, Percent_Identity=40.4545454545455, Blast_Score=318, Evalue=6e-88,
Organism=Escherichia coli, GI1790499, Length=446, Percent_Identity=34.0807174887892, Blast_Score=211, Evalue=8e-56,
Organism=Escherichia coli, GI48994909, Length=430, Percent_Identity=31.6279069767442, Blast_Score=191, Evalue=7e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46248; Mature: 46248

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYFQFDELGTNYKTEFIAGLTTFLSMAYVLFVNPATLSLGNIKGLPAGTGMDPGAVFV
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHH
ATALAAAIGSLIMGIFAKYPIALAPGVGITSFFAYTAVLTMGVPWQTAIAGTLVSGIIFI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IITALGIREKIINAIPAELKLAVAAGIGLFIAFLGFQNAGIIVKNDAVLVGLGDLTKGAT
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCCCCCHH
LLAIFGVVVTIILMIKKINGAVFYGMILTAILGMATGLIDTPKAVVGAIPSLEPTFGMAL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHH
THFGDIFTVQMGIVIITFFFIDFFDTAGTLVAVVNQAGLMKGNKLPRAGKALFADAIATV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
IGAILGTSTTTSYIESSAGVAAGGRSGFTAVVTAGFFLLALFFSPLLSVITPAVTAPALI
HHHHHCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVGILMVSSLGEIEWKKFEIAVPAFFTIISMPLTYSIATGIAIGFIFYPITMVVSGRRKE
HHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
VHPIMYVMGVLFVLYFIYVRK
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKRYFQFDELGTNYKTEFIAGLTTFLSMAYVLFVNPATLSLGNIKGLPAGTGMDPGAVFV
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHH
ATALAAAIGSLIMGIFAKYPIALAPGVGITSFFAYTAVLTMGVPWQTAIAGTLVSGIIFI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IITALGIREKIINAIPAELKLAVAAGIGLFIAFLGFQNAGIIVKNDAVLVGLGDLTKGAT
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCCCCCHH
LLAIFGVVVTIILMIKKINGAVFYGMILTAILGMATGLIDTPKAVVGAIPSLEPTFGMAL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHH
THFGDIFTVQMGIVIITFFFIDFFDTAGTLVAVVNQAGLMKGNKLPRAGKALFADAIATV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
IGAILGTSTTTSYIESSAGVAAGGRSGFTAVVTAGFFLLALFFSPLLSVITPAVTAPALI
HHHHHCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVGILMVSSLGEIEWKKFEIAVPAFFTIISMPLTYSIATGIAIGFIFYPITMVVSGRRKE
HHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
VHPIMYVMGVLFVLYFIYVRK
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969499; 9384377; 11591660 [H]