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The map label for this gene is dnaX [H]

Identifier: 152973871

GI number: 152973871

Start: 25645

End: 27333

Strand: Direct

Name: dnaX [H]

Synonym: Bcer98_0018

Alternate gene names: 152973871

Gene position: 25645-27333 (Clockwise)

Preceding gene: 152973870

Following gene: 152973872

Centisome position: 0.63

GC content: 38.37

Gene sequence:

>1689_bases
GTGTCATACCAAGCGTTATACCGAACATGGAGACCGCAAAAGTTTGCAGATGTAGTCGGTCAAAAGCACGTAACAAAAAC
GTTGCAAAATGCCCTTCTTCAAGAAAAAGCTTCGCATGCTTATTTGTTTTCTGGTCCTAGGGGAACAGGTAAAACAACAA
TTGCAAAAGTATTTGCTAAGGCAATTAACTGTGAGCATGCCCCAGTAGCTGAACCTTGTAATGAATGTCCTGCATGCTTA
GGCATTACACAAGGATCTATTTCGGATGTATTAGAAATTGATGCGGCTTCAAATAACGGTGTAGATGAAATTCGAGATAT
TAGAGATAAGGTAAAATATGCCCCAAGTGCAGTGAAATATAAAGTATACATTATCGATGAAGTTCACATGCTTTCTATGG
GAGCTTTTAATGCACTTTTGAAAACATTAGAAGAACCCCCACAACATGTTATCTTTATTTTAGCAACAACAGAACCTCAT
AAAATTCCACCGACAATTATTTCAAGGTGTCAACGTTTCGAATTTCGAAAAATATCAGTTCATGATATCGTAGAGAGATT
AGAAACTGTTGTAACAAACGAAGGTACAAAGGTAGAAAATGAAGCGTTGCAAATTGTTGCGCGTGCTGCTGAAGGTGGAA
TGCGCGACGCACTTAGTATAATTGACCAAGCTATTTCTTATAGTGATGAAATAGTTACGACTGAGGATGTTTTAGCCGTA
ACGGGTTCTGTTTCACAACAATATTTAGGTAATCTTGTAGAGTGTATACGTGATAATGATGTATCGAGAGCGTTACGTAT
TATTGATGATATGATGAGTAAAGGAAAAGATCCTGTTCGTTTTATGGAAGACTTTATTTATTACTATCGGGATATGCTCT
TATATCAAACTTCACCACAATTAGAACATATGCTAGAACGGGTCATTGTAGACGATCAGTTTCGTATGTTAAGTGAGGCT
ATGCGGCCTGAAGTGATTTATGAAATCATTCATACGCTTAGCAAGGGGCAACAGGAAATGAAATGGACAAATCATCCACG
AATTTTCCTAGAGGTGGTTATGGTTCAACTTTGTCAGCAATTTATGGTGCAAGCAAATGGAACTGACCGCCTACAAGCAA
TTATAAACAGAATGCAACAGCTGGAAAAAGAGCTAGCAGATGTGAAAAAGAATGGTGTTCCTGCTGGTGTCCAGCAGGAA
GTAAGAGAAACTCGTACAGCACCAAAACCAGTGCGAACAGGAAATATGAAAATTCCTGTTGGCCGTGTACATGAAGTGTT
AAAGCAAGCGAAACGCCAAGATTTAGAACAACTAAAGTCTATATGGGGCGAGTTACTAGGGAGATTGAAATCTTACAACA
AAGTAGCATTTGCCGTGTTATTAGAAAATAGTGAACCAGTTGCAGCTTCTGAGGATTCATATGTCTTAGCCTTCCAGTAC
GAGATTCATTGTAAAATGGCAAGTGAGAACCGTGAAGCGATGGATACCGTAGAACAGATTCTATTTGAATTGGTCGGTAA
AAGATTAAATATGATTGCAATTCCGAAAGATCATTGGGGAAAAATCCGTGAAGAATTTTTACAACGTGAAGGCGGAAACT
CAGAGGAATCAAAGGAACAAAGGGTGGATCCTCTCATAGAAGAGGCTGTAAAATTAGTAGGGCAACAACTAATTGAAATA
AAAGAATAA

Upstream 100 bases:

>100_bases
TAAAAGGTGGGTTTTTTGTATAAAAAATAACTTTTGGAATCTATAAACAGAATGGGTTATAATATACAAGATAATAACCT
TTGAGGGAGGCCGTATTTTC

Downstream 100 bases:

>100_bases
GAATGTTTAGGAGGAATTTATTATGATGCGTGGCGGAATGGGAAATATGAATAATATGATGAAACAAATGCAAAAAATGC
AAAAACAAATGGCGAAAGCA

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MSYQALYRTWRPQKFADVVGQKHVTKTLQNALLQEKASHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPACL
GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVKYKVYIIDEVHMLSMGAFNALLKTLEEPPQHVIFILATTEPH
KIPPTIISRCQRFEFRKISVHDIVERLETVVTNEGTKVENEALQIVARAAEGGMRDALSIIDQAISYSDEIVTTEDVLAV
TGSVSQQYLGNLVECIRDNDVSRALRIIDDMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVIVDDQFRMLSEA
MRPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQFMVQANGTDRLQAIINRMQQLEKELADVKKNGVPAGVQQE
VRETRTAPKPVRTGNMKIPVGRVHEVLKQAKRQDLEQLKSIWGELLGRLKSYNKVAFAVLLENSEPVAASEDSYVLAFQY
EIHCKMASENREAMDTVEQILFELVGKRLNMIAIPKDHWGKIREEFLQREGGNSEESKEQRVDPLIEEAVKLVGQQLIEI
KE

Sequences:

>Translated_562_residues
MSYQALYRTWRPQKFADVVGQKHVTKTLQNALLQEKASHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPACL
GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVKYKVYIIDEVHMLSMGAFNALLKTLEEPPQHVIFILATTEPH
KIPPTIISRCQRFEFRKISVHDIVERLETVVTNEGTKVENEALQIVARAAEGGMRDALSIIDQAISYSDEIVTTEDVLAV
TGSVSQQYLGNLVECIRDNDVSRALRIIDDMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVIVDDQFRMLSEA
MRPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQFMVQANGTDRLQAIINRMQQLEKELADVKKNGVPAGVQQE
VRETRTAPKPVRTGNMKIPVGRVHEVLKQAKRQDLEQLKSIWGELLGRLKSYNKVAFAVLLENSEPVAASEDSYVLAFQY
EIHCKMASENREAMDTVEQILFELVGKRLNMIAIPKDHWGKIREEFLQREGGNSEESKEQRVDPLIEEAVKLVGQQLIEI
KE
>Mature_561_residues
SYQALYRTWRPQKFADVVGQKHVTKTLQNALLQEKASHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPACLG
ITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVKYKVYIIDEVHMLSMGAFNALLKTLEEPPQHVIFILATTEPHK
IPPTIISRCQRFEFRKISVHDIVERLETVVTNEGTKVENEALQIVARAAEGGMRDALSIIDQAISYSDEIVTTEDVLAVT
GSVSQQYLGNLVECIRDNDVSRALRIIDDMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVIVDDQFRMLSEAM
RPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQFMVQANGTDRLQAIINRMQQLEKELADVKKNGVPAGVQQEV
RETRTAPKPVRTGNMKIPVGRVHEVLKQAKRQDLEQLKSIWGELLGRLKSYNKVAFAVLLENSEPVAASEDSYVLAFQYE
IHCKMASENREAMDTVEQILFELVGKRLNMIAIPKDHWGKIREEFLQREGGNSEESKEQRVDPLIEEAVKLVGQQLIEIK
E

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=264, Percent_Identity=27.6515151515151, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI194306571, Length=264, Percent_Identity=27.6515151515151, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI194306567, Length=264, Percent_Identity=27.6515151515151, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI31563534, Length=284, Percent_Identity=25.7042253521127, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI194306569, Length=184, Percent_Identity=29.3478260869565, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4506491, Length=368, Percent_Identity=21.195652173913, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI31881687, Length=368, Percent_Identity=21.195652173913, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1786676, Length=356, Percent_Identity=42.6966292134831, Blast_Score=294, Evalue=9e-81,
Organism=Escherichia coli, GI1787119, Length=234, Percent_Identity=26.0683760683761, Blast_Score=66, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71986063, Length=295, Percent_Identity=24.406779661017, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17541988, Length=272, Percent_Identity=26.4705882352941, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17554730, Length=225, Percent_Identity=27.1111111111111, Blast_Score=82, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6324039, Length=306, Percent_Identity=25.4901960784314, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6324478, Length=239, Percent_Identity=26.3598326359833, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322528, Length=309, Percent_Identity=22.6537216828479, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI18859927, Length=290, Percent_Identity=22.4137931034483, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI17647857, Length=284, Percent_Identity=27.112676056338, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19921076, Length=226, Percent_Identity=24.7787610619469, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 63874; Mature: 63743

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQALYRTWRPQKFADVVGQKHVTKTLQNALLQEKASHAYLFSGPRGTGKTTIAKVFAK
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHH
AINCEHAPVAEPCNECPACLGITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVKY
HHCCCCCCCCCHHHHCCHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEE
KVYIIDEVHMLSMGAFNALLKTLEEPPQHVIFILATTEPHKIPPTIISRCQRFEFRKISV
EEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCH
HDIVERLETVVTNEGTKVENEALQIVARAAEGGMRDALSIIDQAISYSDEIVTTEDVLAV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
TGSVSQQYLGNLVECIRDNDVSRALRIIDDMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQ
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHH
LEHMLERVIVDDQFRMLSEAMRPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQ
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHH
FMVQANGTDRLQAIINRMQQLEKELADVKKNGVPAGVQQEVRETRTAPKPVRTGNMKIPV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCH
GRVHEVLKQAKRQDLEQLKSIWGELLGRLKSYNKVAFAVLLENSEPVAASEDSYVLAFQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCEEEEEEE
EIHCKMASENREAMDTVEQILFELVGKRLNMIAIPKDHWGKIREEFLQREGGNSEESKEQ
EEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCCCHHHHH
RVDPLIEEAVKLVGQQLIEIKE
HCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SYQALYRTWRPQKFADVVGQKHVTKTLQNALLQEKASHAYLFSGPRGTGKTTIAKVFAK
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHH
AINCEHAPVAEPCNECPACLGITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVKY
HHCCCCCCCCCHHHHCCHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEE
KVYIIDEVHMLSMGAFNALLKTLEEPPQHVIFILATTEPHKIPPTIISRCQRFEFRKISV
EEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCH
HDIVERLETVVTNEGTKVENEALQIVARAAEGGMRDALSIIDQAISYSDEIVTTEDVLAV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
TGSVSQQYLGNLVECIRDNDVSRALRIIDDMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQ
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHH
LEHMLERVIVDDQFRMLSEAMRPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQ
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHH
FMVQANGTDRLQAIINRMQQLEKELADVKKNGVPAGVQQEVRETRTAPKPVRTGNMKIPV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCH
GRVHEVLKQAKRQDLEQLKSIWGELLGRLKSYNKVAFAVLLENSEPVAASEDSYVLAFQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCEEEEEEE
EIHCKMASENREAMDTVEQILFELVGKRLNMIAIPKDHWGKIREEFLQREGGNSEESKEQ
EEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCCCHHHHH
RVDPLIEEAVKLVGQQLIEIKE
HCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]