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The map label for this gene is tadA [H]

Identifier: 152973870

GI number: 152973870

Start: 24674

End: 25168

Strand: Direct

Name: tadA [H]

Synonym: Bcer98_0017

Alternate gene names: 152973870

Gene position: 24674-25168 (Clockwise)

Preceding gene: 152973866

Following gene: 152973871

Centisome position: 0.6

GC content: 38.79

Gene sequence:

>495_bases
ATGGAACAAGATATGTATTTTATGAAGCTGGCAATAGAAGAAGCGAAGAAAGCGGAGAAGATAGAGGAAGTTCCAATTGG
AGCTGTACTTGTGTTAGATGGCAAAGTAATTAGTAGCGCTCATAACTTAAGGGAGACAGAACAAAGATCGATTGCTCATG
CGGAGTTGTTGGCTATAGATAAGGCTTGTAAAGCTTTGGGAACATGGCGTTTAGAACATGCAACATTATATGTAACCTTG
GAGCCATGTCCGATGTGTGCAGGTGGAATTGTTTTATCACGTGTGAAGCGTGTAGTATATGGTGCAAGTGATCCAAAAGG
TGGATGTGCTGGTACTTTAATGAATCTTTTAACGGATGAACGTTTTAATCATCAATGTGAAGTTGTCTCAGGTGTAATGG
AGGAAGAGTGCGGAGCGCTATTAACAAGCTTCTTTAGAGAACTTCGTAGGAAAAGAAAAGAACAGAAAAAAATTGATAAT
AAAACAAGTTGTTAA

Upstream 100 bases:

>100_bases
TTTTTTTCTTTAGAATGGATTGAATGCTTAAAAGTTATCCAGTATGTATATGGGAATTGGATGAAACTATATTGTAATAG
TGATTAGAGAGGACTGTGTT

Downstream 100 bases:

>100_bases
CACATTTGCATTTTACAAAAAAACAAGTTATACTGATAGTGCCTTGTTTAAGGCAACCGAATATTGGTTTTAACTTTGCC
GTGCTAAGCGGGGAGGTAGC

Product: CMP/dCMP deaminase zinc-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MEQDMYFMKLAIEEAKKAEKIEEVPIGAVLVLDGKVISSAHNLRETEQRSIAHAELLAIDKACKALGTWRLEHATLYVTL
EPCPMCAGGIVLSRVKRVVYGASDPKGGCAGTLMNLLTDERFNHQCEVVSGVMEEECGALLTSFFRELRRKRKEQKKIDN
KTSC

Sequences:

>Translated_164_residues
MEQDMYFMKLAIEEAKKAEKIEEVPIGAVLVLDGKVISSAHNLRETEQRSIAHAELLAIDKACKALGTWRLEHATLYVTL
EPCPMCAGGIVLSRVKRVVYGASDPKGGCAGTLMNLLTDERFNHQCEVVSGVMEEECGALLTSFFRELRRKRKEQKKIDN
KTSC
>Mature_164_residues
MEQDMYFMKLAIEEAKKAEKIEEVPIGAVLVLDGKVISSAHNLRETEQRSIAHAELLAIDKACKALGTWRLEHATLYVTL
EPCPMCAGGIVLSRVKRVVYGASDPKGGCAGTLMNLLTDERFNHQCEVVSGVMEEECGALLTSFFRELRRKRKEQKKIDN
KTSC

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=156, Percent_Identity=31.4102564102564, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI145693172, Length=157, Percent_Identity=45.2229299363057, Blast_Score=142, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI17554608, Length=100, Percent_Identity=50, Blast_Score=97, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17541138, Length=166, Percent_Identity=31.9277108433735, Blast_Score=83, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17555996, Length=80, Percent_Identity=45, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322425, Length=171, Percent_Identity=28.6549707602339, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=30.8219178082192, Blast_Score=70, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 18287; Mature: 18287

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQDMYFMKLAIEEAKKAEKIEEVPIGAVLVLDGKVISSAHNLRETEQRSIAHAELLAID
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
KACKALGTWRLEHATLYVTLEPCPMCAGGIVLSRVKRVVYGASDPKGGCAGTLMNLLTDE
HHHHHHHCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
RFNHQCEVVSGVMEEECGALLTSFFRELRRKRKEQKKIDNKTSC
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEQDMYFMKLAIEEAKKAEKIEEVPIGAVLVLDGKVISSAHNLRETEQRSIAHAELLAID
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
KACKALGTWRLEHATLYVTLEPCPMCAGGIVLSRVKRVVYGASDPKGGCAGTLMNLLTDE
HHHHHHHCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
RFNHQCEVVSGVMEEECGALLTSFFRELRRKRKEQKKIDNKTSC
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]