| Definition | Klebsiella pneumoniae subsp. pneumoniae MGH 78578 chromosome, complete genome. |
|---|---|
| Accession | NC_009648 |
| Length | 5,315,120 |
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The map label for this gene is yfhD [H]
Identifier: 152971414
GI number: 152971414
Start: 3171404
End: 3173020
Strand: Direct
Name: yfhD [H]
Synonym: KPN_02883
Alternate gene names: 152971414
Gene position: 3171404-3173020 (Clockwise)
Preceding gene: 152971408
Following gene: 152971417
Centisome position: 59.67
GC content: 57.08
Gene sequence:
>1617_bases ATGCCGCACATTCGACGACAACCTTGCGTTTTTTCCGGACATCGCCTGCTGAGGAACCTGAAGCTGCAGAAGATTAACTC TCTGAAAAAATTAAAGATTAATTATCTGCTGATCGGCATTGTCACCCTTTTGCTGGCGGCGGCCCTGTGGCCGTCGATCC CCTGGTCTGGTAAACCCGAGAACCGCGTGGCGGGCATTATCGCTCGCGGCGAGCTGCGCATCAGCACCATCAACTCGCCA ATGACCTTCGCCACCATGAACAATAAAGCGTTCGGTCTGGATTATGAACTGGCGAAGCAGTTTGCCGACTACCTTGGCGT CACGCTTAAGATAACCGTCCGGCAAAACATCAGCCAGCTGTTTGACGACCTCGACGACGGTCAGGCCGATATGCTGGCCG CCGGACTGGTCTATAACCAGGAGCGAGTGAAAAACTATCAGGCCGGCCCCACCTACTATTCTGTTTCGCAACAGCTGGTC TACCGCGTCGGCAATACCCGGCCGCGCACCCTCGCGGCGCTGACCGCCGAGCAGCTCACTATCGCTCCGGGCCACGTGGC GATCAACGACCTGCAGACCTTAAAAGCCGAGAAATACCCGGATCTTGCCTGGCGCGTGGACGAAAAACGCGGTACCACGG CGCTGATGCAGGCGGTGATTGACGGTAAACTTGATTACACCATCGCCGACTCGGTGGCCGTCAGCCTGTTTCAGCGCGTC CATCCGGAGCTGGCGGTGGCCCTCGATATCACCGACGAACAGCCGGTCACCTGGTTTAGCGCCCGGGACGACGATAATTC GCTGTCGGCGGCAATGCTTGATTTCTTCAACAACATCAATGAAGACGGCACCCTGGCGCGCCTCGAGGAGAAGTACCTCG GCCACGGCAACGATTTCGATTATGTCGATACCCGCACCTTCCTGCGCGCGGTGGAAAATATTCTTCCGGAGGTGCAGCCG CTGTTTGAAAAATACGCCCGCGAGATTGACTGGCGCCTGCTGGCCGCCATCGCCTGGCAGGAATCCCACTGGGATCCGCA GGCCACCTCCCCTACCGGCGTGCGCGGTATGATGATGCTCACACGCAATACGGCACAAAGCCTGGGTCTAACCGACCGCA CCGATGCGGCGCAGAGTATCGACGGCGGCATGCGCTACCTGCAGGATATGATGGATAAAGTGCCGGATTCGATCCCGAAA GATGAACGCATTTGGTTTGCGCTGGCCGCTTATAATATGGGTTATGCCCATATGCTGGACGCCATGGCGCTCACCCGCAA ACAGAAAGGCAATCCTAACAGCTGGGCGGACGTTAAGCTGCGTTTACCCTTGCTGAGCCAGAAACCCTATTACAGCAAAC TAAAATACGGCTATGCCCGCGGCCATGAGGCCTACGCCTATGTGGAAAACATCCGCAAATATCAGATAAGCCTTGTCGGC TATTTGTCAGAGAAGGAGCGCCAGCAGCAGCAAACGCTGGCCCTGGCGGAGGATTACCCGGCCGTGCTCCCCAATGAGCT CGAACAGCCGCAGGAGACCACCCTGCCCTTTTTCAAGTTTCGCGCCGATAAGCAGATGGATAATGCCCGGATGAAACTCC CCGGCCACCTGTATTAA
Upstream 100 bases:
>100_bases GACGAAACCGTTTGCGTAGAAATAAAATCATTGATGCTGTTTATCAATAAATGTGACGACCATCGCGAATAAGTTGCCAA CTGGCGCATTATTAAGCAGA
Downstream 100 bases:
>100_bases CTTTCCCCAGTCTGCTCCCGGGCTTTCTTCAGCGCTTTTTTCTCTTCCCGCCGCCAGCGGAAGAAGTCGCTCAGCATGGC AGAGCAGGACTCTGCCAGCA
Product: putative transglycosylase
Products: NA
Alternate protein names: Murein lyase F [H]
Number of amino acids: Translated: 538; Mature: 537
Protein sequence:
>538_residues MPHIRRQPCVFSGHRLLRNLKLQKINSLKKLKINYLLIGIVTLLLAAALWPSIPWSGKPENRVAGIIARGELRISTINSP MTFATMNNKAFGLDYELAKQFADYLGVTLKITVRQNISQLFDDLDDGQADMLAAGLVYNQERVKNYQAGPTYYSVSQQLV YRVGNTRPRTLAALTAEQLTIAPGHVAINDLQTLKAEKYPDLAWRVDEKRGTTALMQAVIDGKLDYTIADSVAVSLFQRV HPELAVALDITDEQPVTWFSARDDDNSLSAAMLDFFNNINEDGTLARLEEKYLGHGNDFDYVDTRTFLRAVENILPEVQP LFEKYAREIDWRLLAAIAWQESHWDPQATSPTGVRGMMMLTRNTAQSLGLTDRTDAAQSIDGGMRYLQDMMDKVPDSIPK DERIWFALAAYNMGYAHMLDAMALTRKQKGNPNSWADVKLRLPLLSQKPYYSKLKYGYARGHEAYAYVENIRKYQISLVG YLSEKERQQQQTLALAEDYPAVLPNELEQPQETTLPFFKFRADKQMDNARMKLPGHLY
Sequences:
>Translated_538_residues MPHIRRQPCVFSGHRLLRNLKLQKINSLKKLKINYLLIGIVTLLLAAALWPSIPWSGKPENRVAGIIARGELRISTINSP MTFATMNNKAFGLDYELAKQFADYLGVTLKITVRQNISQLFDDLDDGQADMLAAGLVYNQERVKNYQAGPTYYSVSQQLV YRVGNTRPRTLAALTAEQLTIAPGHVAINDLQTLKAEKYPDLAWRVDEKRGTTALMQAVIDGKLDYTIADSVAVSLFQRV HPELAVALDITDEQPVTWFSARDDDNSLSAAMLDFFNNINEDGTLARLEEKYLGHGNDFDYVDTRTFLRAVENILPEVQP LFEKYAREIDWRLLAAIAWQESHWDPQATSPTGVRGMMMLTRNTAQSLGLTDRTDAAQSIDGGMRYLQDMMDKVPDSIPK DERIWFALAAYNMGYAHMLDAMALTRKQKGNPNSWADVKLRLPLLSQKPYYSKLKYGYARGHEAYAYVENIRKYQISLVG YLSEKERQQQQTLALAEDYPAVLPNELEQPQETTLPFFKFRADKQMDNARMKLPGHLY >Mature_537_residues PHIRRQPCVFSGHRLLRNLKLQKINSLKKLKINYLLIGIVTLLLAAALWPSIPWSGKPENRVAGIIARGELRISTINSPM TFATMNNKAFGLDYELAKQFADYLGVTLKITVRQNISQLFDDLDDGQADMLAAGLVYNQERVKNYQAGPTYYSVSQQLVY RVGNTRPRTLAALTAEQLTIAPGHVAINDLQTLKAEKYPDLAWRVDEKRGTTALMQAVIDGKLDYTIADSVAVSLFQRVH PELAVALDITDEQPVTWFSARDDDNSLSAAMLDFFNNINEDGTLARLEEKYLGHGNDFDYVDTRTFLRAVENILPEVQPL FEKYAREIDWRLLAAIAWQESHWDPQATSPTGVRGMMMLTRNTAQSLGLTDRTDAAQSIDGGMRYLQDMMDKVPDSIPKD ERIWFALAAYNMGYAHMLDAMALTRKQKGNPNSWADVKLRLPLLSQKPYYSKLKYGYARGHEAYAYVENIRKYQISLVGY LSEKERQQQQTLALAEDYPAVLPNELEQPQETTLPFFKFRADKQMDNARMKLPGHLY
Specific function: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the
COG id: COG4623
COG function: function code M; Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein
Gene ontology:
Cell location: Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transglycosylase slt family [H]
Homologues:
Organism=Escherichia coli, GI171474010, Length=481, Percent_Identity=79.8336798336798, Blast_Score=800, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR008258 - InterPro: IPR001638 - InterPro: IPR000189 [H]
Pfam domain/function: PF00497 SBP_bac_3; PF01464 SLT [H]
EC number: NA
Molecular weight: Translated: 61116; Mature: 60984
Theoretical pI: Translated: 7.34; Mature: 7.34
Prosite motif: PS00922 TRANSGLYCOSYLASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 3.0 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPHIRRQPCVFSGHRLLRNLKLQKINSLKKLKINYLLIGIVTLLLAAALWPSIPWSGKPE CCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC NRVAGIIARGELRISTINSPMTFATMNNKAFGLDYELAKQFADYLGVTLKITVRQNISQL CCEEEEEEECEEEEEECCCCEEEEEECCCEECCCHHHHHHHHHHHCEEEEEEEHHHHHHH FDDLDDGQADMLAAGLVYNQERVKNYQAGPTYYSVSQQLVYRVGNTRPRTLAALTAEQLT HHHCCCCCHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHEE IAPGHVAINDLQTLKAEKYPDLAWRVDEKRGTTALMQAVIDGKLDYTIADSVAVSLFQRV ECCCCEEHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHH HPELAVALDITDEQPVTWFSARDDDNSLSAAMLDFFNNINEDGTLARLEEKYLGHGNDFD CCCEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCC YVDTRTFLRAVENILPEVQPLFEKYAREIDWRLLAAIAWQESHWDPQATSPTGVRGMMML CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE TRNTAQSLGLTDRTDAAQSIDGGMRYLQDMMDKVPDSIPKDERIWFALAAYNMGYAHMLD EHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHCCCHHHHHH AMALTRKQKGNPNSWADVKLRLPLLSQKPYYSKLKYGYARGHEAYAYVENIRKYQISLVG HHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH YLSEKERQQQQTLALAEDYPAVLPNELEQPQETTLPFFKFRADKQMDNARMKLPGHLY HHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHCCCHHEEECCCCCCCCCCCCCCCCC >Mature Secondary Structure PHIRRQPCVFSGHRLLRNLKLQKINSLKKLKINYLLIGIVTLLLAAALWPSIPWSGKPE CCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC NRVAGIIARGELRISTINSPMTFATMNNKAFGLDYELAKQFADYLGVTLKITVRQNISQL CCEEEEEEECEEEEEECCCCEEEEEECCCEECCCHHHHHHHHHHHCEEEEEEEHHHHHHH FDDLDDGQADMLAAGLVYNQERVKNYQAGPTYYSVSQQLVYRVGNTRPRTLAALTAEQLT HHHCCCCCHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHEE IAPGHVAINDLQTLKAEKYPDLAWRVDEKRGTTALMQAVIDGKLDYTIADSVAVSLFQRV ECCCCEEHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHH HPELAVALDITDEQPVTWFSARDDDNSLSAAMLDFFNNINEDGTLARLEEKYLGHGNDFD CCCEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCC YVDTRTFLRAVENILPEVQPLFEKYAREIDWRLLAAIAWQESHWDPQATSPTGVRGMMML CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE TRNTAQSLGLTDRTDAAQSIDGGMRYLQDMMDKVPDSIPKDERIWFALAAYNMGYAHMLD EHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHCCCHHHHHH AMALTRKQKGNPNSWADVKLRLPLLSQKPYYSKLKYGYARGHEAYAYVENIRKYQISLVG HHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH YLSEKERQQQQTLALAEDYPAVLPNELEQPQETTLPFFKFRADKQMDNARMKLPGHLY HHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHCCCHHEEECCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA