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The map label for this gene is exoX [H]

Identifier: 152970907

GI number: 152970907

Start: 2583265

End: 2583924

Strand: Direct

Name: exoX [H]

Synonym: KPN_02360

Alternate gene names: 152970907

Gene position: 2583265-2583924 (Clockwise)

Preceding gene: 152970906

Following gene: 152970911

Centisome position: 48.6

GC content: 57.73

Gene sequence:

>660_bases
ATGCTGCGCGTCATTGATACCGAAACCTGCGGCCTGCAGGGGGGCATCGTTGAAATCGCCTCGGTCGATATAGTCGACGG
GCAAATTACCAATCCCATGAGCCATCTGGTGCGTCCCGATCGGCCCATCAGCCCGCAGGCGATGGCTATCCACCGGATCA
CGGAAGAGATGGTCGCCGATAAGCCGTGGATTGAGGAGATTATTCCGCACTATCATGGCAGCCCGTGGTACGTCGCGCAT
AACGCCAGCTTCGATCGCCGGGTGTTGCCGGAGATGCACGGCGAGTGGATCTGTACGATGAAGCTGGCCCGACGCCTGTG
GCCGGGAATCAAATACAGCAATATGGGGTTATATAAGTCACGTAAGCTGAACGTGACTACGCCGCCGGGACTGCATCACC
ACCGGGCGCTGTATGACTGCTATATCACCGCCGCGCTGCTGCTGGATATCATCAATGTTTCCGGCTGGACCCCTGACGAA
ATGGCCGATATCACCGGTCGGCCGGCGCTGCTGACTACTTTTACCTTCGGCAAATACCGGGGTAAGGCCGTCGCCGAGAT
TGCTGAAAACGATCCAGGCTATCTGCGCTGGTTATTCAACAATCTCGACCGCATGAGCCCCGAACTGCGCCTGACGCTCA
GGCATTACCTCGGGGAATAG

Upstream 100 bases:

>100_bases
GTGGGAGCCGAAACAGAAATAATGCGCGCTCGCCTCCTCCCCGTCGGTTGGCAAGCCCGGCCAATTCCATTACGCTTATT
GTTTTGCTCTGGAGCGAGCC

Downstream 100 bases:

>100_bases
CGCCTACACTGCCGCTTTTCCCGGCAGTGTCCCCTGCGCCAGGGCGATGAAAAAGGCGTACTCCAGCGCCACCCCTTCAT
AGCTTTTAAAGCGCCCGGAT

Product: exodeoxyribonuclease X

Products: NA

Alternate protein names: Exodeoxyribonuclease X; Exo X; Exonuclease X [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MLRVIDTETCGLQGGIVEIASVDIVDGQITNPMSHLVRPDRPISPQAMAIHRITEEMVADKPWIEEIIPHYHGSPWYVAH
NASFDRRVLPEMHGEWICTMKLARRLWPGIKYSNMGLYKSRKLNVTTPPGLHHHRALYDCYITAALLLDIINVSGWTPDE
MADITGRPALLTTFTFGKYRGKAVAEIAENDPGYLRWLFNNLDRMSPELRLTLRHYLGE

Sequences:

>Translated_219_residues
MLRVIDTETCGLQGGIVEIASVDIVDGQITNPMSHLVRPDRPISPQAMAIHRITEEMVADKPWIEEIIPHYHGSPWYVAH
NASFDRRVLPEMHGEWICTMKLARRLWPGIKYSNMGLYKSRKLNVTTPPGLHHHRALYDCYITAALLLDIINVSGWTPDE
MADITGRPALLTTFTFGKYRGKAVAEIAENDPGYLRWLFNNLDRMSPELRLTLRHYLGE
>Mature_219_residues
MLRVIDTETCGLQGGIVEIASVDIVDGQITNPMSHLVRPDRPISPQAMAIHRITEEMVADKPWIEEIIPHYHGSPWYVAH
NASFDRRVLPEMHGEWICTMKLARRLWPGIKYSNMGLYKSRKLNVTTPPGLHHHRALYDCYITAALLLDIINVSGWTPDE
MADITGRPALLTTFTFGKYRGKAVAEIAENDPGYLRWLFNNLDRMSPELRLTLRHYLGE

Specific function: Capable of degrading both single-strand and double- strand DNA with 3' to 5' polarity. Has higher affinity for ssDNA ends than for dsDNA. May facilitate recombinational repair by pre- synaptic and/or post-synaptic DNA degradation [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788149, Length=217, Percent_Identity=87.0967741935484, Blast_Score=411, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: 3.1.11.- [C]

Molecular weight: Translated: 25002; Mature: 25002

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRVIDTETCGLQGGIVEIASVDIVDGQITNPMSHLVRPDRPISPQAMAIHRITEEMVAD
CEEEECCCCCCCCCCEEEEEEEEEECCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
KPWIEEIIPHYHGSPWYVAHNASFDRRVLPEMHGEWICTMKLARRLWPGIKYSNMGLYKS
CCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHCCCEEHHHHHHHHHCCCCCCCCCCCCCC
RKLNVTTPPGLHHHRALYDCYITAALLLDIINVSGWTPDEMADITGRPALLTTFTFGKYR
CEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEEECCCCC
GKAVAEIAENDPGYLRWLFNNLDRMSPELRLTLRHYLGE
CHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLRVIDTETCGLQGGIVEIASVDIVDGQITNPMSHLVRPDRPISPQAMAIHRITEEMVAD
CEEEECCCCCCCCCCEEEEEEEEEECCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
KPWIEEIIPHYHGSPWYVAHNASFDRRVLPEMHGEWICTMKLARRLWPGIKYSNMGLYKS
CCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHCCCEEHHHHHHHHHCCCCCCCCCCCCCC
RKLNVTTPPGLHHHRALYDCYITAALLLDIINVSGWTPDEMADITGRPALLTTFTFGKYR
CEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEEECCCCC
GKAVAEIAENDPGYLRWLFNNLDRMSPELRLTLRHYLGE
CHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]