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The map label for this gene is holE [H]

Identifier: 152970906

GI number: 152970906

Start: 2582953

End: 2583186

Strand: Direct

Name: holE [H]

Synonym: KPN_02359

Alternate gene names: 152970906

Gene position: 2582953-2583186 (Clockwise)

Preceding gene: 152970902

Following gene: 152970907

Centisome position: 48.6

GC content: 53.42

Gene sequence:

>234_bases
ATGATGGAAAGAAATCTGGCCAAAATTTCGCAAGATGAGATGGATAAAGTCAATGTCGATCTCGCCGCCGCCGGCGTTGC
TTTTAAGGAGCGGTACAATATGCCGGTGGTCGCTGATTTAGTCGAGCGTGAACAGCCTGCACATCTGCGCGACTGGTTCC
GTGAACGACTGATCGCCCATCGGCTGGCCTCCGTCTCCCTTTCGCGACTACCGTGGGAGCCGAAACAGAAATAA

Upstream 100 bases:

>100_bases
TCCCTTTTGTTATGTCTGTAGCACAGAGAATAACCCTGTATAATGCCAGAGTCGAGCCAGGCATCTGGCCCTGACCGGAT
TTATAAGCAGAGTGGAGTGG

Downstream 100 bases:

>100_bases
TGCGCGCTCGCCTCCTCCCCGTCGGTTGGCAAGCCCGGCCAATTCCATTACGCTTATTGTTTTGCTCTGGAGCGAGCCAT
GCTGCGCGTCATTGATACCG

Product: DNA polymerase III subunit theta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 77; Mature: 77

Protein sequence:

>77_residues
MMERNLAKISQDEMDKVNVDLAAAGVAFKERYNMPVVADLVEREQPAHLRDWFRERLIAHRLASVSLSRLPWEPKQK

Sequences:

>Translated_77_residues
MMERNLAKISQDEMDKVNVDLAAAGVAFKERYNMPVVADLVEREQPAHLRDWFRERLIAHRLASVSLSRLPWEPKQK
>Mature_77_residues
MMERNLAKISQDEMDKVNVDLAAAGVAFKERYNMPVVADLVEREQPAHLRDWFRERLIAHRLASVSLSRLPWEPKQK

Specific function: The exact function of the theta subunit is unknown [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788147, Length=76, Percent_Identity=82.8947368421053, Blast_Score=131, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009052
- InterPro:   IPR011325
- ProDom:   PD057609 [H]

Pfam domain/function: PF06440 DNA_pol3_theta [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 9003; Mature: 9003

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMERNLAKISQDEMDKVNVDLAAAGVAFKERYNMPVVADLVEREQPAHLRDWFRERLIAH
CCCCHHHHCCHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHH
RLASVSLSRLPWEPKQK
HHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MMERNLAKISQDEMDKVNVDLAAAGVAFKERYNMPVVADLVEREQPAHLRDWFRERLIAH
CCCCHHHHCCHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHH
RLASVSLSRLPWEPKQK
HHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]