| Definition | Klebsiella pneumoniae subsp. pneumoniae MGH 78578 chromosome, complete genome. |
|---|---|
| Accession | NC_009648 |
| Length | 5,315,120 |
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The map label for this gene is fdhF [H]
Identifier: 152970639
GI number: 152970639
Start: 2290424
End: 2292574
Strand: Direct
Name: fdhF [H]
Synonym: KPN_02090
Alternate gene names: 152970639
Gene position: 2290424-2292574 (Clockwise)
Preceding gene: 152970638
Following gene: 152970641
Centisome position: 43.09
GC content: 62.72
Gene sequence:
>2151_bases ATGAAAAAAATCACGAGCGTGTGCCCCTACTGCGGGGCGGGTTGCAAACTTAAACTGGTTGTCGACAACAATAAAATCAT TCGCGCGGAAGCCGCCGACGGCGTCACCAACCAGAACCAGCTGTGCCTGAAAGGCTACTACGGCTGGGATTTTCTTAACG ATACGCAGCTCCTGACGCCCCGTCTTAAACAACCGATGATCCGCTACCAGAAAGGCGGCGCCTTCACGCCGGTCAGCTGG CAGGAGGCGATTCGCTATACCGCCAGCAAGCTCAGGGAGATCAAAGAGAAGCATGGCCCGCGCGCCATCATGACCACCGG CTCCTCGCGCGGCACCGGCAACGAAACCAACTATGTGATGCAAAAGTTCGCCCGCGCGGTACTGAACACCAATAACGTCG ACTGCTGCGCCCGCGTCTGCCACGGCCCCTCCGTCGCCGGGCTACAGCAGGCGCTGGGCAACGGGGCGATGAGCAACTCG ATTAGCGACATCGAAAACTCGAAGTGCCTGCTGGTCTTTGGCTACAACTGCGCCGACTCCCATCCCATCGTCGCCCGCCG GGTAATCAAGGCCCGGGACAACGGCGCCAAAATCATCGTCTGCGATCCGCGGCGCATTGAAACCGCGCGCATTGCCGATC GTCATCTGCAGCTCAACAACGGCAGCAACATGGCGCTGGTAAATGCCTTCGGCTATGTGCTGCTGGAGGAGGAGCTGTAC AACAAAACCTATGTCGAACGCTATACCGAAGGGCTGGATGCTTACCGCGAGGCGGTGAAGGATTACGCCCCGGAAGCGGT GGAAGGGATTGTCGGGGTCAGCGCGCGGGAAATCCGGGAGGCGATGCGCATGTTCGCCGCCGCCCCATCCGCCACCATTA TGTGGGGCATGGGGGTCACCCAGTTTGGCCAGGCGGTGGACGTGGTGCGCGGCCTGGCAAGCCTGGCGCTGCTCACCGGC AACCTGGGACGGCCCAACGTCGGCGTGGGGCCGGTCCGCGGGCAAAACAACGTACAGGGCGCCTGCGATATGGGCGTGCT GCCGAACCTGTTCCCCGGCTATCAGGAGGTCACCGACCCCGCCGTGCGGGCGAAATTCGCCGCCGCCTGGGGCATCGACC CGGCGCTGATGGACGACCAGGTCGGCACCCGCATCACCGAGGTGCCGCATAAAGCGCTGACCGGCGAGATCAAAGCCTAT TATATCATGGGCGAAGATCCGCTGCAGACCGAAGCCGACCTCGGCCTGGTGCGCAAAGGCATCGAGGCGCTGGACTTCGT GGTCGTGCAGGACATCTTCATGACCAAAACAGCGGAAATGGCCGATGTCCTGCTGCCGGCCACCTCCTGGGGCGAGCACG GCGGCGTCTTCACCTGCGCCGACCGCGGGTTCCAGCGGTTTGAACAGGCGATCCCTCCGGCGGGGAATGTGAAGCGCGAC TGGGAGATCATTAGCCTGCTGGCCAGCGAATTGGGCTATCCGATGCACTATGAGAACAACCAGCAGATCTGGGACGAGAT GCGCGAGCTCTGCCCGCTGTTCTACGGCGTGACCTGGGAGAAAATGGGCGATATGGGCCATGTCCAGTGGCCGTGCCCGA CCCTCGATCATCCCGGCACGCCATGGCTGTATAAAGACAACCGCTTCGACACCCCCTCGGGTAAAGGGCAGCTGTTCGCC ACCGCCTGGCGCGCGCCGGCGGAGCGCCCGGATGACGAGTGGCCGCTGGTGCTGTGCACCGTGCGGGAAGTCGGGCATTA TTCCTGCCGCTCGATGACCGGCAACTGCGCCGCGCTGCAGTCGCTGGCCGACGAGCCGGGACGGGTGCAGATGAATCCCG CGGATGCGCAACGACTGGGGATCGCCGACAAACAGCTGGTGTGGATCAGCTCCCGGCGCGGGAAGGTGATCTCCCGCGCC GACCTCAGCGATCGCATCAATCCGGGGGCGGTCTATATGACCTATCAGTGGTGGGTGGGCGCCTGCAATGAGCTGACCCA GGATAACCTCGATCCGATCTCCAAAACGCCGGAAACCAAATACTGTGCGGTGAAAGTGGAAGCGATTGCCGACCAGCAAT GGGCGGAGCGCTATGCCTGGACGGCCTACAGCGACATGAAAGCGCGACTGAAAGCCGCTGCCGACGTCTGA
Upstream 100 bases:
>100_bases AGGCCTGCGTCTGCATCACCACCAGGCGATACCGCGATCGTTGCCCGTCGGGCCCGGCGCGACAGCGATCCTCAGTTCAC TGTTAACAGGTCTGTTACTG
Downstream 100 bases:
>100_bases CCTCAGGGAGCGCAGCGCGCTCCCTCTGCCGCTGCCGGTGGGTTACGCCGCCGGCAGCTGTTTCTCCACCAGCCCCACCC ACATGGCGACCCCGGGGCCG
Product: formate dehydrogenase H, selenopolypeptide subunit
Products: NA
Alternate protein names: Formate dehydrogenase-H subunit alpha; FDH-H; Formate-hydrogen-lyase-linked, selenocysteine-containing polypeptide [H]
Number of amino acids: Translated: 716; Mature: 716
Protein sequence:
>716_residues MKKITSVCPYCGAGCKLKLVVDNNKIIRAEAADGVTNQNQLCLKGYYGWDFLNDTQLLTPRLKQPMIRYQKGGAFTPVSW QEAIRYTASKLREIKEKHGPRAIMTTGSSRGTGNETNYVMQKFARAVLNTNNVDCCARVCHGPSVAGLQQALGNGAMSNS ISDIENSKCLLVFGYNCADSHPIVARRVIKARDNGAKIIVCDPRRIETARIADRHLQLNNGSNMALVNAFGYVLLEEELY NKTYVERYTEGLDAYREAVKDYAPEAVEGIVGVSAREIREAMRMFAAAPSATIMWGMGVTQFGQAVDVVRGLASLALLTG NLGRPNVGVGPVRGQNNVQGACDMGVLPNLFPGYQEVTDPAVRAKFAAAWGIDPALMDDQVGTRITEVPHKALTGEIKAY YIMGEDPLQTEADLGLVRKGIEALDFVVVQDIFMTKTAEMADVLLPATSWGEHGGVFTCADRGFQRFEQAIPPAGNVKRD WEIISLLASELGYPMHYENNQQIWDEMRELCPLFYGVTWEKMGDMGHVQWPCPTLDHPGTPWLYKDNRFDTPSGKGQLFA TAWRAPAERPDDEWPLVLCTVREVGHYSCRSMTGNCAALQSLADEPGRVQMNPADAQRLGIADKQLVWISSRRGKVISRA DLSDRINPGAVYMTYQWWVGACNELTQDNLDPISKTPETKYCAVKVEAIADQQWAERYAWTAYSDMKARLKAAADV
Sequences:
>Translated_716_residues MKKITSVCPYCGAGCKLKLVVDNNKIIRAEAADGVTNQNQLCLKGYYGWDFLNDTQLLTPRLKQPMIRYQKGGAFTPVSW QEAIRYTASKLREIKEKHGPRAIMTTGSSRGTGNETNYVMQKFARAVLNTNNVDCCARVCHGPSVAGLQQALGNGAMSNS ISDIENSKCLLVFGYNCADSHPIVARRVIKARDNGAKIIVCDPRRIETARIADRHLQLNNGSNMALVNAFGYVLLEEELY NKTYVERYTEGLDAYREAVKDYAPEAVEGIVGVSAREIREAMRMFAAAPSATIMWGMGVTQFGQAVDVVRGLASLALLTG NLGRPNVGVGPVRGQNNVQGACDMGVLPNLFPGYQEVTDPAVRAKFAAAWGIDPALMDDQVGTRITEVPHKALTGEIKAY YIMGEDPLQTEADLGLVRKGIEALDFVVVQDIFMTKTAEMADVLLPATSWGEHGGVFTCADRGFQRFEQAIPPAGNVKRD WEIISLLASELGYPMHYENNQQIWDEMRELCPLFYGVTWEKMGDMGHVQWPCPTLDHPGTPWLYKDNRFDTPSGKGQLFA TAWRAPAERPDDEWPLVLCTVREVGHYSCRSMTGNCAALQSLADEPGRVQMNPADAQRLGIADKQLVWISSRRGKVISRA DLSDRINPGAVYMTYQWWVGACNELTQDNLDPISKTPETKYCAVKVEAIADQQWAERYAWTAYSDMKARLKAAADV >Mature_716_residues MKKITSVCPYCGAGCKLKLVVDNNKIIRAEAADGVTNQNQLCLKGYYGWDFLNDTQLLTPRLKQPMIRYQKGGAFTPVSW QEAIRYTASKLREIKEKHGPRAIMTTGSSRGTGNETNYVMQKFARAVLNTNNVDCCARVCHGPSVAGLQQALGNGAMSNS ISDIENSKCLLVFGYNCADSHPIVARRVIKARDNGAKIIVCDPRRIETARIADRHLQLNNGSNMALVNAFGYVLLEEELY NKTYVERYTEGLDAYREAVKDYAPEAVEGIVGVSAREIREAMRMFAAAPSATIMWGMGVTQFGQAVDVVRGLASLALLTG NLGRPNVGVGPVRGQNNVQGACDMGVLPNLFPGYQEVTDPAVRAKFAAAWGIDPALMDDQVGTRITEVPHKALTGEIKAY YIMGEDPLQTEADLGLVRKGIEALDFVVVQDIFMTKTAEMADVLLPATSWGEHGGVFTCADRGFQRFEQAIPPAGNVKRD WEIISLLASELGYPMHYENNQQIWDEMRELCPLFYGVTWEKMGDMGHVQWPCPTLDHPGTPWLYKDNRFDTPSGKGQLFA TAWRAPAERPDDEWPLVLCTVREVGHYSCRSMTGNCAALQSLADEPGRVQMNPADAQRLGIADKQLVWISSRRGKVISRA DLSDRINPGAVYMTYQWWVGACNELTQDNLDPISKTPETKYCAVKVEAIADQQWAERYAWTAYSDMKARLKAAADV
Specific function: Decomposes formic acid to hydrogen and carbon dioxide under anaerobic conditions in the absence of exogenous electron acceptors [H]
COG id: COG0243
COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]
Homologues:
Organism=Escherichia coli, GI3868721, Length=716, Percent_Identity=66.0614525139665, Blast_Score=1014, Evalue=0.0, Organism=Escherichia coli, GI1788534, Length=790, Percent_Identity=24.6835443037975, Blast_Score=213, Evalue=3e-56, Organism=Escherichia coli, GI3868720, Length=432, Percent_Identity=28.7037037037037, Blast_Score=169, Evalue=7e-43, Organism=Escherichia coli, GI3868719, Length=622, Percent_Identity=24.91961414791, Blast_Score=165, Evalue=1e-41, Organism=Escherichia coli, GI87081797, Length=796, Percent_Identity=24.748743718593, Blast_Score=136, Evalue=5e-33, Organism=Escherichia coli, GI171474008, Length=782, Percent_Identity=25.3196930946292, Blast_Score=127, Evalue=3e-30, Organism=Escherichia coli, GI1787778, Length=682, Percent_Identity=22.8739002932551, Blast_Score=126, Evalue=6e-30, Organism=Escherichia coli, GI1787870, Length=789, Percent_Identity=23.9543726235741, Blast_Score=124, Evalue=1e-29, Organism=Escherichia coli, GI87081994, Length=701, Percent_Identity=22.9671897289586, Blast_Score=101, Evalue=1e-22, Organism=Escherichia coli, GI1787231, Length=687, Percent_Identity=22.707423580786, Blast_Score=99, Evalue=1e-21, Organism=Escherichia coli, GI145693196, Length=681, Percent_Identity=21.5859030837004, Blast_Score=96, Evalue=6e-21,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR009010 - InterPro: IPR006478 - InterPro: IPR006657 - InterPro: IPR006656 - InterPro: IPR006963 - InterPro: IPR006655 [H]
Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]
EC number: =1.2.1.2 [H]
Molecular weight: Translated: 79213; Mature: 79213
Theoretical pI: Translated: 6.51; Mature: 6.51
Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.7 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 5.9 %Cys+Met (Translated Protein) 2.7 %Cys (Mature Protein) 3.2 %Met (Mature Protein) 5.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKITSVCPYCGAGCKLKLVVDNNKIIRAEAADGVTNQNQLCLKGYYGWDFLNDTQLLTP CCCHHHHCCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCHHHCH RLKQPMIRYQKGGAFTPVSWQEAIRYTASKLREIKEKHGPRAIMTTGSSRGTGNETNYVM HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHH QKFARAVLNTNNVDCCARVCHGPSVAGLQQALGNGAMSNSISDIENSKCLLVFGYNCADS HHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHCCCHHCCCHHHCCCCCEEEEEECCCCCC HPIVARRVIKARDNGAKIIVCDPRRIETARIADRHLQLNNGSNMALVNAFGYVLLEEELY CCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHEEEECCCCCEEEEEHHHHHEEHHHHH NKTYVERYTEGLDAYREAVKDYAPEAVEGIVGVSAREIREAMRMFAAAPSATIMWGMGVT HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCHH QFGQAVDVVRGLASLALLTGNLGRPNVGVGPVRGQNNVQGACDMGVLPNLFPGYQEVTDP HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCH AVRAKFAAAWGIDPALMDDQVGTRITEVPHKALTGEIKAYYIMGEDPLQTEADLGLVRKG HHHHHHHHHCCCCHHHCCCHHCCHHHHCCHHHHCCCEEEEEEECCCCCCCHHHHHHHHHH IEALDFVVVQDIFMTKTAEMADVLLPATSWGEHGGVFTCADRGFQRFEQAIPPAGNVKRD HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCHH WEIISLLASELGYPMHYENNQQIWDEMRELCPLFYGVTWEKMGDMGHVQWPCPTLDHPGT HHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCC PWLYKDNRFDTPSGKGQLFATAWRAPAERPDDEWPLVLCTVREVGHYSCRSMTGNCAALQ CCEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEHHHCCHHHHCCCCCHHHHH SLADEPGRVQMNPADAQRLGIADKQLVWISSRRGKVISRADLSDRINPGAVYMTYQWWVG HHCCCCCEEEECCCCHHHHCCCCCEEEEEECCCCCEEEECCCCCCCCCCEEEEEEEHHHH ACNELTQDNLDPISKTPETKYCAVKVEAIADQQWAERYAWTAYSDMKARLKAAADV HHHHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MKKITSVCPYCGAGCKLKLVVDNNKIIRAEAADGVTNQNQLCLKGYYGWDFLNDTQLLTP CCCHHHHCCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCHHHCH RLKQPMIRYQKGGAFTPVSWQEAIRYTASKLREIKEKHGPRAIMTTGSSRGTGNETNYVM HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHH QKFARAVLNTNNVDCCARVCHGPSVAGLQQALGNGAMSNSISDIENSKCLLVFGYNCADS HHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHCCCHHCCCHHHCCCCCEEEEEECCCCCC HPIVARRVIKARDNGAKIIVCDPRRIETARIADRHLQLNNGSNMALVNAFGYVLLEEELY CCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHEEEECCCCCEEEEEHHHHHEEHHHHH NKTYVERYTEGLDAYREAVKDYAPEAVEGIVGVSAREIREAMRMFAAAPSATIMWGMGVT HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCHH QFGQAVDVVRGLASLALLTGNLGRPNVGVGPVRGQNNVQGACDMGVLPNLFPGYQEVTDP HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCH AVRAKFAAAWGIDPALMDDQVGTRITEVPHKALTGEIKAYYIMGEDPLQTEADLGLVRKG HHHHHHHHHCCCCHHHCCCHHCCHHHHCCHHHHCCCEEEEEEECCCCCCCHHHHHHHHHH IEALDFVVVQDIFMTKTAEMADVLLPATSWGEHGGVFTCADRGFQRFEQAIPPAGNVKRD HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCHH WEIISLLASELGYPMHYENNQQIWDEMRELCPLFYGVTWEKMGDMGHVQWPCPTLDHPGT HHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCC PWLYKDNRFDTPSGKGQLFATAWRAPAERPDDEWPLVLCTVREVGHYSCRSMTGNCAALQ CCEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEHHHCCHHHHCCCCCHHHHH SLADEPGRVQMNPADAQRLGIADKQLVWISSRRGKVISRADLSDRINPGAVYMTYQWWVG HHCCCCCEEEECCCCHHHHCCCCCEEEEEECCCCCEEEECCCCCCCCCCEEEEEEEHHHH ACNELTQDNLDPISKTPETKYCAVKVEAIADQQWAERYAWTAYSDMKARLKAAADV HHHHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2941757; 8265357; 9278503; 2211698; 9036855 [H]