| Definition | Klebsiella pneumoniae subsp. pneumoniae MGH 78578 chromosome, complete genome. |
|---|---|
| Accession | NC_009648 |
| Length | 5,315,120 |
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The map label for this gene is ykvO [H]
Identifier: 152969740
GI number: 152969740
Start: 1335628
End: 1336377
Strand: Direct
Name: ykvO [H]
Synonym: KPN_01186
Alternate gene names: 152969740
Gene position: 1335628-1336377 (Clockwise)
Preceding gene: 152969738
Following gene: 152969742
Centisome position: 25.13
GC content: 64.8
Gene sequence:
>750_bases ATGAGCAAAAAACTTGCGGATAAAGTGGCGTTAGTCACCGGCGGCAGCGCCGGGATTGGCCTGGCGTCGGCGAAAGCACT GGCGGAGCAGGGCGCGAAGGTGTACATCACCGGCCGCCGTCAGGAGGAGCTGGATGCGGCGGTAAGATTCATCGGACCCG CCGCCCGCGCGATCCGCGCCGACGCCGCCGTGTTAAGCGACCTTGACGCGGTATTTGCGACCATTGCCGAAGAGTCCGGC CGGCTGGATGTGCTGTTCGCCAATGCCGGCGGCGGGGATATGCTGCCGCTGAGCGCCATCACCGAAGCGCACGTCGACCG AATTTTTGCCACCAACGTGCGCGGGGTGGTGTTCACCGTGCAAAAAGCGCTGCCGCTGCTCACCGATGGCGCCTCGGTGA TTTTGACCGGCTCTACGGCGGCGGTAAAAGGGACGGCTAACTTCAGCATCTATAGCGCCAGTAAGGCCGCGGTACGCAGC CTGGCGCGCTCCTGGGCGCTGGAGGTTAGCGACCGCGGGATCCGCATCAATGTGGTCAGCCCGGGTCCGGTACGTACCCC GGGTCTGGGAGGGCTGGTGGCGGAGGCGGACCGCCAGGGCTTGTTCGATGCTCTGGCGGCCGGTGTACCGCTCGGGCGGC TGGGCGAGCCGGAGGAGATTGGCCGGACGGTGGTATTTTTAGCGTCGGATGAGTCGAGCTTTATTAACGCCGCGGAGATC TATGTCGACGGCGGGCTGGCGCAAATCTAA
Upstream 100 bases:
>100_bases CCATTTTTCCGCCTCGCCGGGACGATTACAGTGCTTTCCATACCCGGCGGGGCGCGTTCGCGAGCCTGGCCTGTTTATAC TCTAACCAAGGAAATGCACC
Downstream 100 bases:
>100_bases GCGCCTGCCGTCGCCGCACTGACCTGACCGGGCAGAGGCGCTTTCAGCAGGGCGATCAGCAGCGTACTGCCCACCATGAT CCCCGCCGCCAGCCACACCA
Product: oxidoreductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 249; Mature: 248
Protein sequence:
>249_residues MSKKLADKVALVTGGSAGIGLASAKALAEQGAKVYITGRRQEELDAAVRFIGPAARAIRADAAVLSDLDAVFATIAEESG RLDVLFANAGGGDMLPLSAITEAHVDRIFATNVRGVVFTVQKALPLLTDGASVILTGSTAAVKGTANFSIYSASKAAVRS LARSWALEVSDRGIRINVVSPGPVRTPGLGGLVAEADRQGLFDALAAGVPLGRLGEPEEIGRTVVFLASDESSFINAAEI YVDGGLAQI
Sequences:
>Translated_249_residues MSKKLADKVALVTGGSAGIGLASAKALAEQGAKVYITGRRQEELDAAVRFIGPAARAIRADAAVLSDLDAVFATIAEESG RLDVLFANAGGGDMLPLSAITEAHVDRIFATNVRGVVFTVQKALPLLTDGASVILTGSTAAVKGTANFSIYSASKAAVRS LARSWALEVSDRGIRINVVSPGPVRTPGLGGLVAEADRQGLFDALAAGVPLGRLGEPEEIGRTVVFLASDESSFINAAEI YVDGGLAQI >Mature_248_residues SKKLADKVALVTGGSAGIGLASAKALAEQGAKVYITGRRQEELDAAVRFIGPAARAIRADAAVLSDLDAVFATIAEESGR LDVLFANAGGGDMLPLSAITEAHVDRIFATNVRGVVFTVQKALPLLTDGASVILTGSTAAVKGTANFSIYSASKAAVRSL ARSWALEVSDRGIRINVVSPGPVRTPGLGGLVAEADRQGLFDALAAGVPLGRLGEPEEIGRTVVFLASDESSFINAAEIY VDGGLAQI
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=35.3658536585366, Blast_Score=116, Evalue=2e-26, Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=30.7692307692308, Blast_Score=115, Evalue=4e-26, Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=31.4285714285714, Blast_Score=107, Evalue=8e-24, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=29.2, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=33.0645161290323, Blast_Score=95, Evalue=5e-20, Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=29.4573643410853, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI33667109, Length=187, Percent_Identity=32.620320855615, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=29.7619047619048, Blast_Score=91, Evalue=8e-19, Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=29.718875502008, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI15277342, Length=266, Percent_Identity=30.0751879699248, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI4503301, Length=250, Percent_Identity=32.4, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI59889578, Length=229, Percent_Identity=31.0043668122271, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=30.3867403314917, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI223718074, Length=195, Percent_Identity=35.8974358974359, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI7657478, Length=199, Percent_Identity=32.1608040201005, Blast_Score=71, Evalue=7e-13, Organism=Homo sapiens, GI31542939, Length=202, Percent_Identity=30.1980198019802, Blast_Score=69, Evalue=4e-12, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=34.8, Blast_Score=122, Evalue=2e-29, Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=30.8, Blast_Score=110, Evalue=6e-26, Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=33.0612244897959, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI1786812, Length=247, Percent_Identity=34.0080971659919, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=30.4, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=29.5546558704453, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI2367365, Length=239, Percent_Identity=33.0543933054393, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=30.4, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=28.8617886178862, Blast_Score=84, Evalue=8e-18, Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=29.8387096774194, Blast_Score=84, Evalue=9e-18, Organism=Escherichia coli, GI1786701, Length=197, Percent_Identity=30.9644670050761, Blast_Score=78, Evalue=5e-16, Organism=Escherichia coli, GI1787526, Length=191, Percent_Identity=30.8900523560209, Blast_Score=74, Evalue=9e-15, Organism=Escherichia coli, GI1787820, Length=179, Percent_Identity=28.4916201117318, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=26.4, Blast_Score=67, Evalue=9e-13, Organism=Escherichia coli, GI1787545, Length=256, Percent_Identity=24.21875, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=33.8403041825095, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=33.5907335907336, Blast_Score=114, Evalue=6e-26, Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=35.9848484848485, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=30.5882352941176, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=36.5019011406844, Blast_Score=107, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=31.3953488372093, Blast_Score=107, Evalue=6e-24, Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=31.8181818181818, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=31.0861423220974, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=32.0754716981132, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=30.5343511450382, Blast_Score=103, Evalue=9e-23, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=32.9545454545455, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=32.824427480916, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=32.7067669172932, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=34.5098039215686, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=30.2681992337165, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=32.1705426356589, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=31.6602316602317, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=31.8725099601594, Blast_Score=97, Evalue=9e-21, Organism=Caenorhabditis elegans, GI25147288, Length=257, Percent_Identity=30.3501945525292, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=33.2075471698113, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=28.0769230769231, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=29.8387096774194, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=30.9803921568627, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=27.9245283018868, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=31.8725099601594, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17561272, Length=257, Percent_Identity=33.0739299610895, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17538182, Length=255, Percent_Identity=32.5490196078431, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=28.968253968254, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17568967, Length=252, Percent_Identity=27.3809523809524, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI71997099, Length=205, Percent_Identity=31.219512195122, Blast_Score=67, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322067, Length=212, Percent_Identity=31.6037735849057, Blast_Score=83, Evalue=3e-17, Organism=Saccharomyces cerevisiae, GI6324126, Length=251, Percent_Identity=27.8884462151394, Blast_Score=81, Evalue=2e-16, Organism=Saccharomyces cerevisiae, GI6322227, Length=193, Percent_Identity=31.0880829015544, Blast_Score=69, Evalue=8e-13, Organism=Saccharomyces cerevisiae, GI6323882, Length=198, Percent_Identity=29.7979797979798, Blast_Score=65, Evalue=8e-12, Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=36.8421052631579, Blast_Score=124, Evalue=6e-29, Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=35.2226720647773, Blast_Score=117, Evalue=7e-27, Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=31.8897637795276, Blast_Score=117, Evalue=9e-27, Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=33.739837398374, Blast_Score=111, Evalue=4e-25, Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=30.5220883534137, Blast_Score=107, Evalue=7e-24, Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=31.3008130081301, Blast_Score=105, Evalue=2e-23, Organism=Drosophila melanogaster, GI24639444, Length=254, Percent_Identity=33.0708661417323, Blast_Score=100, Evalue=9e-22, Organism=Drosophila melanogaster, GI17737361, Length=257, Percent_Identity=30.3501945525292, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI24644337, Length=248, Percent_Identity=31.4516129032258, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI116007236, Length=220, Percent_Identity=30, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24641232, Length=225, Percent_Identity=30.6666666666667, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI116007238, Length=194, Percent_Identity=29.3814432989691, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI21356301, Length=202, Percent_Identity=26.7326732673267, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 25503; Mature: 25372
Theoretical pI: Translated: 5.10; Mature: 5.10
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 0.8 %Met (Translated Protein) 0.8 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 0.4 %Met (Mature Protein) 0.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSKKLADKVALVTGGSAGIGLASAKALAEQGAKVYITGRRQEELDAAVRFIGPAARAIRA CCCHHHCEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCHHHHHHHH DAAVLSDLDAVFATIAEESGRLDVLFANAGGGDMLPLSAITEAHVDRIFATNVRGVVFTV HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEH QKALPLLTDGASVILTGSTAAVKGTANFSIYSASKAAVRSLARSWALEVSDRGIRINVVS HHHCCEEECCCEEEEECCCEEEEECCCEEEEECHHHHHHHHHHHHEEEECCCCEEEEEEC PGPVRTPGLGGLVAEADRQGLFDALAAGVPLGRLGEPEEIGRTVVFLASDESSFINAAEI CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEEEEECCCCCCEEEEEE YVDGGLAQI EECCCCCCC >Mature Secondary Structure SKKLADKVALVTGGSAGIGLASAKALAEQGAKVYITGRRQEELDAAVRFIGPAARAIRA CCHHHCEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCHHHHHHHH DAAVLSDLDAVFATIAEESGRLDVLFANAGGGDMLPLSAITEAHVDRIFATNVRGVVFTV HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEH QKALPLLTDGASVILTGSTAAVKGTANFSIYSASKAAVRSLARSWALEVSDRGIRINVVS HHHCCEEECCCEEEEECCCEEEEECCCEEEEECHHHHHHHHHHHHEEEECCCCEEEEEEC PGPVRTPGLGGLVAEADRQGLFDALAAGVPLGRLGEPEEIGRTVVFLASDESSFINAAEI CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEEEEECCCCCCEEEEEE YVDGGLAQI EECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]