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The map label for this gene is nadA [H]

Identifier: 152969311

GI number: 152969311

Start: 839642

End: 840688

Strand: Direct

Name: nadA [H]

Synonym: KPN_00754

Alternate gene names: 152969311

Gene position: 839642-840688 (Clockwise)

Preceding gene: 152969310

Following gene: 152969312

Centisome position: 15.8

GC content: 59.98

Gene sequence:

>1047_bases
ATGATGAGCGTAATGTTTGATCCTGAAACGGCGATTTATCCTTTCCCTGCTAAACCGCAGCCGCTGACCGTCGACGAAAA
GCAGTTTTACCGCGAAAAAATCAAGCGCCTGCTACGCGAGCGCGATGCCGTGATGGTGGCGCATTACTACACCGATCCTG
AAATTCAACAGCTGGCGGAAGAGACCGGCGGCTGTATCGCCGACTCGCTGGAGATGGCGCGCTTTGGCGCCCGCCATTCG
GCCTCCACGCTGCTGGTCGCCGGGGTGCGTTTTATGGGGGAAACCGCCAAAATTCTCAGCCCGGAAAAGACCATTTTGAT
GCCGACCCTGAACGCCGAGTGTTCATTGGATCTGGGCTGTCCGATTGAGGAATTCAACGCCTTTTGCGACGCCCATCCTG
ACCGCACCGTCGTGGTCTATGCCAATACGTCCGCCGCGGTGAAGGCCCGCGCCGACTGGGTGGTGACCTCCAGCATCGCC
GTGGAACTCATTGACCATCTGGATAGTCTTGGTCAAAAGATCCTCTGGGCGCCGGACCGCCACCTTGGGCGTTACGTTCA
GCGTCAGACCGGCGCAGACGTGCTGTGCTGGCAGGGGGCGTGCATCGTGCACGACGAGTTTAAAACCCAGGCGTTGATGC
GGATGAAGGCTCTGCATCCCGAAGCCGCCGTGCTGGTCCATCCCGAGTCGCCGCAGGCGATCGTTGAGATGGCCGATGCC
GTAGGCTCCACCAGCCAGCTGATTGCGGCGGCGAAAAGCCTGCCCCAGCGCCAGCTGATCGTGGCCACCGATCGCGGTAT
TTTCTATAAAATGCAGCAGGCGGTGCCGGAGAAAACGCTGCTGGAAGCGCCCACCGCCGGCGAAGGAGCGACCTGTCGCA
GCTGCGCGCATTGTCCGTGGATGGCGATGAATGGCCTGAAAGCCATTGCCGAGGGTCTCGAGCAGGGCGGCGCTGCACAT
GAAATCCATGTCGACGAAGCGCTGCGAACCGGCGCATTAATTCCCCTTAACCGGATGCTGGATTTTGCGGCTACACTACG
GGGATAA

Upstream 100 bases:

>100_bases
AATCGGCTATCTTGTTTAGCATATAAAACACCATGACCGTATTAAGCCGCCGACAGGCCATACTGACGGTTATAGAGTTA
AGCCAGTAAAACGAGATTGC

Downstream 100 bases:

>100_bases
CCTATTGTCGCGTCGCCAGACGCTGAGGGGAGGAAATGGATTTTTTTAGCACGCAGAATATTTTAGTACATATACCCATC
GGCGCTGGGGGGTACGATCT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MMSVMFDPETAIYPFPAKPQPLTVDEKQFYREKIKRLLRERDAVMVAHYYTDPEIQQLAEETGGCIADSLEMARFGARHS
ASTLLVAGVRFMGETAKILSPEKTILMPTLNAECSLDLGCPIEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIA
VELIDHLDSLGQKILWAPDRHLGRYVQRQTGADVLCWQGACIVHDEFKTQALMRMKALHPEAAVLVHPESPQAIVEMADA
VGSTSQLIAAAKSLPQRQLIVATDRGIFYKMQQAVPEKTLLEAPTAGEGATCRSCAHCPWMAMNGLKAIAEGLEQGGAAH
EIHVDEALRTGALIPLNRMLDFAATLRG

Sequences:

>Translated_348_residues
MMSVMFDPETAIYPFPAKPQPLTVDEKQFYREKIKRLLRERDAVMVAHYYTDPEIQQLAEETGGCIADSLEMARFGARHS
ASTLLVAGVRFMGETAKILSPEKTILMPTLNAECSLDLGCPIEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIA
VELIDHLDSLGQKILWAPDRHLGRYVQRQTGADVLCWQGACIVHDEFKTQALMRMKALHPEAAVLVHPESPQAIVEMADA
VGSTSQLIAAAKSLPQRQLIVATDRGIFYKMQQAVPEKTLLEAPTAGEGATCRSCAHCPWMAMNGLKAIAEGLEQGGAAH
EIHVDEALRTGALIPLNRMLDFAATLRG
>Mature_348_residues
MMSVMFDPETAIYPFPAKPQPLTVDEKQFYREKIKRLLRERDAVMVAHYYTDPEIQQLAEETGGCIADSLEMARFGARHS
ASTLLVAGVRFMGETAKILSPEKTILMPTLNAECSLDLGCPIEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIA
VELIDHLDSLGQKILWAPDRHLGRYVQRQTGADVLCWQGACIVHDEFKTQALMRMKALHPEAAVLVHPESPQAIVEMADA
VGSTSQLIAAAKSLPQRQLIVATDRGIFYKMQQAVPEKTLLEAPTAGEGATCRSCAHCPWMAMNGLKAIAEGLEQGGAAH
EIHVDEALRTGALIPLNRMLDFAATLRG

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=347, Percent_Identity=87.0317002881844, Blast_Score=646, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 38110; Mature: 38110

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSVMFDPETAIYPFPAKPQPLTVDEKQFYREKIKRLLRERDAVMVAHYYTDPEIQQLAE
CCCEEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHH
ETGGCIADSLEMARFGARHSASTLLVAGVRFMGETAKILSPEKTILMPTLNAECSLDLGC
HHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCCCEECCC
PIEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIDHLDSLGQKILWAPDR
CHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHHHHCHHEECCCCH
HLGRYVQRQTGADVLCWQGACIVHDEFKTQALMRMKALHPEAAVLVHPESPQAIVEMADA
HHHHHHHHHCCCCEEEECCEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
VGSTSQLIAAAKSLPQRQLIVATDRGIFYKMQQAVPEKTLLEAPTAGEGATCRSCAHCPW
HCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCHHHHHCCCCCCCCCCCHHHCCCCH
MAMNGLKAIAEGLEQGGAAHEIHVDEALRTGALIPLNRMLDFAATLRG
HHHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MMSVMFDPETAIYPFPAKPQPLTVDEKQFYREKIKRLLRERDAVMVAHYYTDPEIQQLAE
CCCEEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHH
ETGGCIADSLEMARFGARHSASTLLVAGVRFMGETAKILSPEKTILMPTLNAECSLDLGC
HHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCCCEECCC
PIEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIDHLDSLGQKILWAPDR
CHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHHHHCHHEECCCCH
HLGRYVQRQTGADVLCWQGACIVHDEFKTQALMRMKALHPEAAVLVHPESPQAIVEMADA
HHHHHHHHHCCCCEEEECCEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
VGSTSQLIAAAKSLPQRQLIVATDRGIFYKMQQAVPEKTLLEAPTAGEGATCRSCAHCPW
HCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCHHHHHCCCCCCCCCCCHHHCCCCH
MAMNGLKAIAEGLEQGGAAHEIHVDEALRTGALIPLNRMLDFAATLRG
HHHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA