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The map label for this gene is lyx [H]

Identifier: 152969206

GI number: 152969206

Start: 721006

End: 722502

Strand: Direct

Name: lyx [H]

Synonym: KPN_00635

Alternate gene names: 152969206

Gene position: 721006-722502 (Clockwise)

Preceding gene: 152969205

Following gene: 152969207

Centisome position: 13.57

GC content: 66.93

Gene sequence:

>1497_bases
ATGGATTTTTATCTTGGTATCGATATTGGCACCTCGCGGGTGAAAGCGGTGCTGTTTGATCAGCATTTCACCGCCTGCGC
CAGCGCCGCGGAAAACACCTCACCCCGCCTGTCGGCCAATGGCTACGCGGAACAGGATATGACCCAGCTGTGGCATTCGG
TGCTGGCTATTCTGCGCCAGATTGCCCGCCATCCGGCGCTACAGGCGGGGCGGCTGCGGGCTATCGGCCTCGCCGGGCAA
GGGGAGGGGGTCTGGCTCAGCGATGAGCAGGGCGAACCGGTGGGCCCGGGGATCCTGTGGAGCGATACCCGCAGCCACGA
GCTAATGAGCGACCTGCTGCGCCGACCCGGCTTCGACCGCCGCTATTTCGCCGATACCGGCACCCACCTGCAGCCCTGCA
ATACCAGCCTGCAGCTGTACTGGCTGAAACAGTATCAGCCGGCGCGGCTGGCGGCCGCGCGCTATCTGTTTTTCGCCAAG
GACTGGATCCGCTTTCGCCTGACCGGCGTGGCGGCGCTGGAGCTGACGGACGCCAGCAGCTCGTTACTCAATCAGCAGAC
CGGCAGCTGGTCCTCGGTGGTGATGAACGAGATGGGGCTGAACGAACTGCTGCCGCTGTTTCCCCCGCTGCTGGCCCCGG
ATGCCCCGGCCGGCACGCTGAGCGACGCGGTGGCGGCGCTGACCGGGCTGCCCGCCGCGACGCCGGTGGCCGCCGGGGCG
CTGGATGTCTGTAGCGCCGCGCTGGGCTGCGGCGCGGTCAACGAAGGGGATATCTACACGATCCTCGGCACCACCTGCTG
CACCGGGATCGTCTGCCGCGGCCCGCAGACGGTGAACGAGGCGACGCGCTTTGTCACCCATACCGAAGCCGGACAGGTGA
TCTCCCTGTTTCCGATGCAGGCCGGTACGCCAAACATTGACTGGCTGCAGCAGCATATTTCGCTGGACGCCGATCTGGGG
CGCCTGGAGCAGGCGATCGCGGCGGTGGAGCCAGGCAGCGGCGGCGTCTTCTGGCAGCCGTACCTCAATGGCGAACGTGC
TCCGTTTTACAGCCCGGACGCGCGGGCCGGCTTTTTCGGCATTAGCCCGCACACCACCCGCGCCCAACTGCAGCGCGCGG
TGTTTGAAGGCCTGGCCTTCGCCATTGTCGATGCGCTGCAGGGTTATCCGCAGGGCGGCGAGCTGTATCTGACCGGCGGC
GGCGCAGCCTCGGCGACCTGGCTGCAGATTATCGCAGACTGTACCGGACGCACGGTGGTCTCCAGCGCCTTTAACGAACT
GAGCGCGCGCGGCGCGGCGATCCTGGCGGCCCGTAGCGTCGCGGCGCTGGCCGAGACGCCTCCGCTGGCGCAGACCCGCT
ATCAGCCGCGCCCTCAGGCGCATGCCCGCTACGCGGCGCTGTATCCCGTTTACCGCCTGCTGCGCGAGCAGATGCTGCCG
GTATGGCAGGCCAGACAGGCCGCCCTTCAACCTCTTTCTCAGGACCTACAACCATGA

Upstream 100 bases:

>100_bases
GAAAGATATTCAGGAGGCCCGCCGTCAACTGGAGGGGCTGGAGTTCCTGTTCGAGTGCGAGCTGATGCGCCGCCGCTACG
AGCCCTGAGCCGGAGCAGGT

Downstream 100 bases:

>100_bases
AAATCGTTTTTACCGCCGAGCATGCTGGCGACCTTAGCGCCTTCCACCAGCTGGGCGAGCTGCTGGTGGAGGGGTGGGCG
CTGGGCAAACCGAAACTCAG

Product: putative carbohydrate kinase, FGGY

Products: NA

Alternate protein names: L-xylulokinase [H]

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MDFYLGIDIGTSRVKAVLFDQHFTACASAAENTSPRLSANGYAEQDMTQLWHSVLAILRQIARHPALQAGRLRAIGLAGQ
GEGVWLSDEQGEPVGPGILWSDTRSHELMSDLLRRPGFDRRYFADTGTHLQPCNTSLQLYWLKQYQPARLAAARYLFFAK
DWIRFRLTGVAALELTDASSSLLNQQTGSWSSVVMNEMGLNELLPLFPPLLAPDAPAGTLSDAVAALTGLPAATPVAAGA
LDVCSAALGCGAVNEGDIYTILGTTCCTGIVCRGPQTVNEATRFVTHTEAGQVISLFPMQAGTPNIDWLQQHISLDADLG
RLEQAIAAVEPGSGGVFWQPYLNGERAPFYSPDARAGFFGISPHTTRAQLQRAVFEGLAFAIVDALQGYPQGGELYLTGG
GAASATWLQIIADCTGRTVVSSAFNELSARGAAILAARSVAALAETPPLAQTRYQPRPQAHARYAALYPVYRLLREQMLP
VWQARQAALQPLSQDLQP

Sequences:

>Translated_498_residues
MDFYLGIDIGTSRVKAVLFDQHFTACASAAENTSPRLSANGYAEQDMTQLWHSVLAILRQIARHPALQAGRLRAIGLAGQ
GEGVWLSDEQGEPVGPGILWSDTRSHELMSDLLRRPGFDRRYFADTGTHLQPCNTSLQLYWLKQYQPARLAAARYLFFAK
DWIRFRLTGVAALELTDASSSLLNQQTGSWSSVVMNEMGLNELLPLFPPLLAPDAPAGTLSDAVAALTGLPAATPVAAGA
LDVCSAALGCGAVNEGDIYTILGTTCCTGIVCRGPQTVNEATRFVTHTEAGQVISLFPMQAGTPNIDWLQQHISLDADLG
RLEQAIAAVEPGSGGVFWQPYLNGERAPFYSPDARAGFFGISPHTTRAQLQRAVFEGLAFAIVDALQGYPQGGELYLTGG
GAASATWLQIIADCTGRTVVSSAFNELSARGAAILAARSVAALAETPPLAQTRYQPRPQAHARYAALYPVYRLLREQMLP
VWQARQAALQPLSQDLQP
>Mature_498_residues
MDFYLGIDIGTSRVKAVLFDQHFTACASAAENTSPRLSANGYAEQDMTQLWHSVLAILRQIARHPALQAGRLRAIGLAGQ
GEGVWLSDEQGEPVGPGILWSDTRSHELMSDLLRRPGFDRRYFADTGTHLQPCNTSLQLYWLKQYQPARLAAARYLFFAK
DWIRFRLTGVAALELTDASSSLLNQQTGSWSSVVMNEMGLNELLPLFPPLLAPDAPAGTLSDAVAALTGLPAATPVAAGA
LDVCSAALGCGAVNEGDIYTILGTTCCTGIVCRGPQTVNEATRFVTHTEAGQVISLFPMQAGTPNIDWLQQHISLDADLG
RLEQAIAAVEPGSGGVFWQPYLNGERAPFYSPDARAGFFGISPHTTRAQLQRAVFEGLAFAIVDALQGYPQGGELYLTGG
GAASATWLQIIADCTGRTVVSSAFNELSARGAAILAARSVAALAETPPLAQTRYQPRPQAHARYAALYPVYRLLREQMLP
VWQARQAALQPLSQDLQP

Specific function: L-lyxose utilization. [C]

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI88196792, Length=515, Percent_Identity=22.5242718446602, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1790005, Length=497, Percent_Identity=29.7786720321932, Blast_Score=192, Evalue=6e-50,
Organism=Escherichia coli, GI1789987, Length=495, Percent_Identity=29.2929292929293, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI1789168, Length=493, Percent_Identity=27.5862068965517, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790361, Length=494, Percent_Identity=24.2914979757085, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787789, Length=500, Percent_Identity=25.2, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790338, Length=500, Percent_Identity=22.2, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17535599, Length=500, Percent_Identity=24, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17864214, Length=470, Percent_Identity=23.8297872340426, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24654573, Length=393, Percent_Identity=24.6819338422392, Blast_Score=96, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.53 [H]

Molecular weight: Translated: 53566; Mature: 53566

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFYLGIDIGTSRVKAVLFDQHFTACASAAENTSPRLSANGYAEQDMTQLWHSVLAILRQ
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IARHPALQAGRLRAIGLAGQGEGVWLSDEQGEPVGPGILWSDTRSHELMSDLLRRPGFDR
HHHCCCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCC
RYFADTGTHLQPCNTSLQLYWLKQYQPARLAAARYLFFAKDWIRFRLTGVAALELTDASS
EEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHEEEEEEEEEEECCCHH
SLLNQQTGSWSSVVMNEMGLNELLPLFPPLLAPDAPAGTLSDAVAALTGLPAATPVAAGA
HHHHHCCCCHHHHHHHHCCHHHHHHHCCHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHH
LDVCSAALGCGAVNEGDIYTILGTTCCTGIVCRGPQTVNEATRFVTHTEAGQVISLFPMQ
HHHHHHHHCCCCCCCCCEEEEEHHHHHCCEEECCCCHHHHHHHHHEECCCCCEEEEEECC
AGTPNIDWLQQHISLDADLGRLEQAIAAVEPGSGGVFWQPYLNGERAPFYSPDARAGFFG
CCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEC
ISPHTTRAQLQRAVFEGLAFAIVDALQGYPQGGELYLTGGGAASATWLQIIADCTGRTVV
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCHHHH
SSAFNELSARGAAILAARSVAALAETPPLAQTRYQPRPQAHARYAALYPVYRLLREQMLP
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCH
VWQARQAALQPLSQDLQP
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDFYLGIDIGTSRVKAVLFDQHFTACASAAENTSPRLSANGYAEQDMTQLWHSVLAILRQ
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IARHPALQAGRLRAIGLAGQGEGVWLSDEQGEPVGPGILWSDTRSHELMSDLLRRPGFDR
HHHCCCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCC
RYFADTGTHLQPCNTSLQLYWLKQYQPARLAAARYLFFAKDWIRFRLTGVAALELTDASS
EEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHEEEEEEEEEEECCCHH
SLLNQQTGSWSSVVMNEMGLNELLPLFPPLLAPDAPAGTLSDAVAALTGLPAATPVAAGA
HHHHHCCCCHHHHHHHHCCHHHHHHHCCHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHH
LDVCSAALGCGAVNEGDIYTILGTTCCTGIVCRGPQTVNEATRFVTHTEAGQVISLFPMQ
HHHHHHHHCCCCCCCCCEEEEEHHHHHCCEEECCCCHHHHHHHHHEECCCCCEEEEEECC
AGTPNIDWLQQHISLDADLGRLEQAIAAVEPGSGGVFWQPYLNGERAPFYSPDARAGFFG
CCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEC
ISPHTTRAQLQRAVFEGLAFAIVDALQGYPQGGELYLTGGGAASATWLQIIADCTGRTVV
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCHHHH
SSAFNELSARGAAILAARSVAALAETPPLAQTRYQPRPQAHARYAALYPVYRLLREQMLP
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCH
VWQARQAALQPLSQDLQP
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]