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The map label for this gene is gmhB [H]

Identifier: 152968795

GI number: 152968795

Start: 248514

End: 249131

Strand: Direct

Name: gmhB [H]

Synonym: KPN_00214

Alternate gene names: 152968795

Gene position: 248514-249131 (Clockwise)

Preceding gene: 152968787

Following gene: 152968796

Centisome position: 4.68

GC content: 53.07

Gene sequence:

>618_bases
ATGCGGAAACATGCGATACTAGCGGCACTAGTCTTTTTCAGGAGCAAACCGGTGGCAAAGTCAGTACCCGCAATTTTTCT
CGACCGTGACGGCACTATTAATGTCGATCATGGCTACGTCCACGAAATCGACAATTTTGAATTTATCGATGGCGTCATTG
ACGCGATGCGCGAACTAAAAGAGATGGGCTACGCGCTGGTGCTGGTCACTAACCAGTCCGGTATTGCCCGCGGTAAATTT
ACCGAAGCCCAGTTTGAAACGCTGACCGAATGGATGGACTGGTCTCTGGCAGACCGCGGCGTCGACCTCGACGGTATCTA
CTATTGCCCGCATCACCCGCAGGGTGCGGTTGAGGAGTACCGCCAGACCTGTGATTGTCGTAAACCGCATCCGGGGATGC
TGATTTCCGCCCGCGATTATCTGCATATCGATATGGCTGCTTCTTATATGGTAGGGGACAAACTGGAAGATATGCAGGCG
GCAGCGGCTGCGGATGTCGGGACTAAAGTACTGGTGCGCACCGGTAAGCCCCTGACTGAAGAAGCGGAAAAAGCGGCGAA
TTGGGTGCTAAATAGCCTGGCAGAGCTGCCGGCGGCGATTAAAAAGCAGCAAAAATAA

Upstream 100 bases:

>100_bases
TTTCTTCTGCCGTATCCAGGCGATGCCTGGCAATGAAATGGATGTTAAGGCATCCAGACGTCTAAATCAATCTGACTCTT
TATAATGAGCACTTTCTTGC

Downstream 100 bases:

>100_bases
GCGTTGCGTTTAAAAGATGAGCGGTTGAAATAAAATTGTATTTTTCCGCTTGTCATTCCCGGAGAGCTCCCTATAATGCG
CCTCCATCGACACGGCAGAT

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MRKHAILAALVFFRSKPVAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKEMGYALVLVTNQSGIARGKF
TEAQFETLTEWMDWSLADRGVDLDGIYYCPHHPQGAVEEYRQTCDCRKPHPGMLISARDYLHIDMAASYMVGDKLEDMQA
AAAADVGTKVLVRTGKPLTEEAEKAANWVLNSLAELPAAIKKQQK

Sequences:

>Translated_205_residues
MRKHAILAALVFFRSKPVAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKEMGYALVLVTNQSGIARGKF
TEAQFETLTEWMDWSLADRGVDLDGIYYCPHHPQGAVEEYRQTCDCRKPHPGMLISARDYLHIDMAASYMVGDKLEDMQA
AAAADVGTKVLVRTGKPLTEEAEKAANWVLNSLAELPAAIKKQQK
>Mature_205_residues
MRKHAILAALVFFRSKPVAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKEMGYALVLVTNQSGIARGKF
TEAQFETLTEWMDWSLADRGVDLDGIYYCPHHPQGAVEEYRQTCDCRKPHPGMLISARDYLHIDMAASYMVGDKLEDMQA
AAAADVGTKVLVRTGKPLTEEAEKAANWVLNSLAELPAAIKKQQK

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=188, Percent_Identity=90.9574468085106, Blast_Score=366, Evalue=1e-103,
Organism=Escherichia coli, GI87082027, Length=140, Percent_Identity=33.5714285714286, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: 3.1.1.-

Molecular weight: Translated: 22883; Mature: 22883

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKHAILAALVFFRSKPVAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELK
CCHHHHHHHHHHHHCCCCHHCCCEEEECCCCEEECCCCEEECCCCCHHHHHHHHHHHHHH
EMGYALVLVTNQSGIARGKFTEAQFETLTEWMDWSLADRGVDLDGIYYCPHHPQGAVEEY
HCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHCCCCCCCEEECCCCCCHHHHHH
RQTCDCRKPHPGMLISARDYLHIDMAASYMVGDKLEDMQAAAAADVGTKVLVRTGKPLTE
HHHCCCCCCCCCEEEECCCEEEEHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCHH
EAEKAANWVLNSLAELPAAIKKQQK
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKHAILAALVFFRSKPVAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELK
CCHHHHHHHHHHHHCCCCHHCCCEEEECCCCEEECCCCEEECCCCCHHHHHHHHHHHHHH
EMGYALVLVTNQSGIARGKFTEAQFETLTEWMDWSLADRGVDLDGIYYCPHHPQGAVEEY
HCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHCCCCCCCEEECCCCCCHHHHHH
RQTCDCRKPHPGMLISARDYLHIDMAASYMVGDKLEDMQAAAAADVGTKVLVRTGKPLTE
HHHCCCCCCCCCEEEECCCEEEEHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCHH
EAEKAANWVLNSLAELPAAIKKQQK
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11108008; 11206551; 11258796 [H]