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The map label for this gene is cutF [H]

Identifier: 152968787

GI number: 152968787

Start: 241038

End: 241757

Strand: Direct

Name: cutF [H]

Synonym: KPN_00206

Alternate gene names: 152968787

Gene position: 241038-241757 (Clockwise)

Preceding gene: 152968786

Following gene: 152968795

Centisome position: 4.53

GC content: 57.64

Gene sequence:

>720_bases
ATGGATGATAAGGAAAGCAAAGTGAAGAAAATCGTATTCTCCGTGATAGCGGCCTGTTCGCTGTTCGCGCTGTTTGGTTG
TAACCATCGCGCCGAGACTGACACGGTCCAGCCAGCGGCGATGGAAGAGCTCAAGCCGATGCAGCAAAGCTGGCGAGGCG
TGCTGCCTTGCGCGGATTGCGAAGGTATCGACACCTCGCTGTTCCTGGAAAAAGACGGGACCTGGGTGATGAATGAGCAC
TACCAGGGCGCCCGTCGTGAGCCGTCATCCTTTGCCTCGTACGGCACCTGGGCACGTACCGCGGATAAGCTGGTGCTGAC
CAACAGCAAGGGCGAGAAATCTTACTTTCGCGCGAAAGGCGACAAGCTGGAGATGCTCGACCGCAACGGAAGCCCCATTC
AGTCTCCTCTCAACTATACCCTGGAGCCAGTGAAGGCCAGCCTGCCGACGACGCCGATGGCGATGCGCGGCATGTATTTC
TATATGGCCGATGCGGCAACCTTTACCGATTGCGCGACCGGTAAACGCGTCGCGGTGGCGAACAATGCCCAGCTTGAACG
GGATTATGCCGCCGCGCGCGGGACCGATACTCGCCCGGTACTGCTGGTGGTAGAAGGGCACTTTACTCTCGAAGCGAACC
CGGATACCGGCGAGATGATGAAAACGCTGATGACGGATCAAGCCGGCAAATTTATTCCCGGTAAAGACTGCAGCCATTGA

Upstream 100 bases:

>100_bases
GGCATCGAAAGAGCGACGCCTTGCTTCCAAGGCACAGAAGTCCTCAGTCAAGGCGCTGCGTGGGAAAGTTCGCCAGTGAA
GGCGTCGGCGAACGGGTGAA

Downstream 100 bases:

>100_bases
TTGTCAGGCCCCTGTCCGGGTAACGGGCAGGGGATGATCCCGCGCAGTACCACCTACTTCCTCCTGTTATTAGCCCTGTC
ACATCAAGAGTGAGCGTGGA

Product: lipoprotein involved with copper homeostasis and adhesion

Products: NA

Alternate protein names: Copper homeostasis protein CutF [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MDDKESKVKKIVFSVIAACSLFALFGCNHRAETDTVQPAAMEELKPMQQSWRGVLPCADCEGIDTSLFLEKDGTWVMNEH
YQGARREPSSFASYGTWARTADKLVLTNSKGEKSYFRAKGDKLEMLDRNGSPIQSPLNYTLEPVKASLPTTPMAMRGMYF
YMADAATFTDCATGKRVAVANNAQLERDYAAARGTDTRPVLLVVEGHFTLEANPDTGEMMKTLMTDQAGKFIPGKDCSH

Sequences:

>Translated_239_residues
MDDKESKVKKIVFSVIAACSLFALFGCNHRAETDTVQPAAMEELKPMQQSWRGVLPCADCEGIDTSLFLEKDGTWVMNEH
YQGARREPSSFASYGTWARTADKLVLTNSKGEKSYFRAKGDKLEMLDRNGSPIQSPLNYTLEPVKASLPTTPMAMRGMYF
YMADAATFTDCATGKRVAVANNAQLERDYAAARGTDTRPVLLVVEGHFTLEANPDTGEMMKTLMTDQAGKFIPGKDCSH
>Mature_239_residues
MDDKESKVKKIVFSVIAACSLFALFGCNHRAETDTVQPAAMEELKPMQQSWRGVLPCADCEGIDTSLFLEKDGTWVMNEH
YQGARREPSSFASYGTWARTADKLVLTNSKGEKSYFRAKGDKLEMLDRNGSPIQSPLNYTLEPVKASLPTTPMAMRGMYF
YMADAATFTDCATGKRVAVANNAQLERDYAAARGTDTRPVLLVVEGHFTLEANPDTGEMMKTLMTDQAGKFIPGKDCSH

Specific function: Involved in copper homeostasis. Could be involved in both copper efflux and the delivery of copper to copper-dependent enzymes. When overproduced induces degP through the activation of the two-component system CpxA/CpxR [H]

COG id: COG3015

COG function: function code MP; Uncharacterized lipoprotein NlpE involved in copper resistance

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786390, Length=231, Percent_Identity=74.8917748917749, Blast_Score=367, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007298 [H]

Pfam domain/function: PF04170 NlpE [H]

EC number: NA

Molecular weight: Translated: 26403; Mature: 26403

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDKESKVKKIVFSVIAACSLFALFGCNHRAETDTVQPAAMEELKPMQQSWRGVLPCADC
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
EGIDTSLFLEKDGTWVMNEHYQGARREPSSFASYGTWARTADKLVLTNSKGEKSYFRAKG
CCCCCEEEEECCCCEEECCCCCCCCCCCHHHHHCCCHHHCCCEEEEECCCCCHHHHHCCC
DKLEMLDRNGSPIQSPLNYTLEPVKASLPTTPMAMRGMYFYMADAATFTDCATGKRVAVA
CEEEEECCCCCCCCCCCCCEECHHHCCCCCCCHHHHCEEEEEECCCHHHHCCCCCEEEEE
NNAQLERDYAAARGTDTRPVLLVVEGHFTLEANPDTGEMMKTLMTDQAGKFIPGKDCSH
CCCHHHHHHHHHCCCCCCCEEEEEECCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDDKESKVKKIVFSVIAACSLFALFGCNHRAETDTVQPAAMEELKPMQQSWRGVLPCADC
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
EGIDTSLFLEKDGTWVMNEHYQGARREPSSFASYGTWARTADKLVLTNSKGEKSYFRAKG
CCCCCEEEEECCCCEEECCCCCCCCCCCHHHHHCCCHHHCCCEEEEECCCCCHHHHHCCC
DKLEMLDRNGSPIQSPLNYTLEPVKASLPTTPMAMRGMYFYMADAATFTDCATGKRVAVA
CEEEEECCCCCCCCCCCCCEECHHHCCCCCCCHHHHCEEEEEECCCHHHHCCCCCEEEEE
NNAQLERDYAAARGTDTRPVLLVVEGHFTLEANPDTGEMMKTLMTDQAGKFIPGKDCSH
CCCHHHHHHHHHCCCCCCCEEEEEECCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7635808; 7635807; 9278503 [H]