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The map label for this gene is serS

Identifier: 150401905

GI number: 150401905

Start: 1543531

End: 1545099

Strand: Reverse

Name: serS

Synonym: Maeo_1483

Alternate gene names: 150401905

Gene position: 1545099-1543531 (Counterclockwise)

Preceding gene: 150401906

Following gene: 150401900

Centisome position: 98.45

GC content: 32.5

Gene sequence:

>1569_bases
ATGAAATTTGAATTAAATGGTAAAATTATATTTAGTAAGGAAATTACTGATGATGCCAAAAAAGATATAATTGAAGTATT
GAATGATAGAACCATATTATTAAAAGGAGTGCCTACTGGAAAAGAGGAAGAAGCTTCAAAAATAGTAAATTATGAATTTA
AAGGCAATGAATTAATATTAAACATAATTTCAGGCACTTATGCGAGAGCCCATGAGGCAATTATTAGATTAAAAAAACCA
ATAATGGAAAAAGTTGGGAAAATTCACAAAATGGGAATAAGAGATATAAAAATAGATAATTACGAAATAACAATTAATGC
CCCCCACAATATAGATGCCCTTGAAAATTTAAAAGTACCAGAATGTGAAACAGAATTAAACGAAGAAGAAAATACTATAA
AAATCATATTTAAAAATATTGGAGATAGTGAATTAAAAAGAAATATTGTAGATAGAGCAATTAAATTTGTAAAAACAGAA
ATTGACAACATTGGAGATAGTGGCGAAGAGTGCGATTTAACTTATGAAGTGTGTGGAATAGCTCCAAATACAATTGTATC
AGAATATAAGGCAGAAAGAACAATATCATATAATAAAGACCCAACAGAAGAAAGCGAAAAATTAGGCTGGGTTAAGCGAT
TTTCTGGAAAAGGTCAATGGTTTTACACTCCACCAATGACTAAATTATTAAGGGCTTTTGAGGAGCTCCTTATGGAAGAA
TGCATAAATAAAATTGGATTTGATGAATGTTTATTCCCAAAACTTATTCCATTGGAAGTTATGTACAAAATGAGATATTT
GGAAGGGCTTCCTGAGGGAATGTATTATGTATCTCCGCCAAAAAGAGACCCAGAGATGTTTAAAGAGTTTGTAAATGAAA
TGATGATTAAAAATGAAATCCCAATACATAAATTAAAAGACCTTCTTAGAAATCCGGGGTATGTGTTGGCACCTGCCCAA
TGTGAGCCATTCTATCAATTCTTTGACCATGAATTAGTGGATATTGATAATCCAGTTAAATTTGTGGATAAAAGTGGCTG
GACATACAGATGGGAAGGAGGAGGCTCAAAAGGGCTTGATAGAGTTCATGAATTTTTAAGAATAGAAACAGTTCAAATGG
GAGCTCCTGAATTTGTAAATAGCGTAAGAGATGACACATTGAAATATGCCGAAAAACTTGCTGAAAAACTTGATTTAGAG
TATTGGACCGAGGTAGGAGACGACCCATTTTATTTAGAGGGAAGGAAAAAAGAGGAAAGAAACATAGAATTCCCAGAAGT
TCCAAAATATGAAATGAGATTATGGCTCCCTCATGTAAAAGATGAAAGAAAAGGAGTTGCCGTAACATCAGCAAATGTTC
ATGGAACTCATTTTGTAGAAGGATTTGGTGTAAAAGATTACAAAAACAGAACGGTATGGACAGGATGCACAGGATTTGGG
CTTAGTAGATGGGTAATAGGATTTTTGGCACAATATGGATTTGACTACAACGACTGGCCGGAATTAATTAAAGATAAAAT
TGGAGAAATGCCAAATATACCAAAAGTAATTACTTGGCCTAAAAAATAA

Upstream 100 bases:

>100_bases
GATTTTGAGATAATTTAGTGAAATAGTTCGAAGATTGACTATATACACAATATATATGGCAATATAATATTTTATAATTT
AACGATATAATGGTGATTTT

Downstream 100 bases:

>100_bases
AATATTATAAATTATATTTTTTTTATTTTTTATTGTATATCCATATACATACCGAAAAGTATATATATTAGATTTATCAT
TTTATATTGTGTTCTATACT

Product: seryl-tRNA synthetase

Products: NA

Alternate protein names: Serine--tRNA ligase; SerRS; Seryl-tRNA(Ser/Sec) synthetase

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MKFELNGKIIFSKEITDDAKKDIIEVLNDRTILLKGVPTGKEEEASKIVNYEFKGNELILNIISGTYARAHEAIIRLKKP
IMEKVGKIHKMGIRDIKIDNYEITINAPHNIDALENLKVPECETELNEEENTIKIIFKNIGDSELKRNIVDRAIKFVKTE
IDNIGDSGEECDLTYEVCGIAPNTIVSEYKAERTISYNKDPTEESEKLGWVKRFSGKGQWFYTPPMTKLLRAFEELLMEE
CINKIGFDECLFPKLIPLEVMYKMRYLEGLPEGMYYVSPPKRDPEMFKEFVNEMMIKNEIPIHKLKDLLRNPGYVLAPAQ
CEPFYQFFDHELVDIDNPVKFVDKSGWTYRWEGGGSKGLDRVHEFLRIETVQMGAPEFVNSVRDDTLKYAEKLAEKLDLE
YWTEVGDDPFYLEGRKKEERNIEFPEVPKYEMRLWLPHVKDERKGVAVTSANVHGTHFVEGFGVKDYKNRTVWTGCTGFG
LSRWVIGFLAQYGFDYNDWPELIKDKIGEMPNIPKVITWPKK

Sequences:

>Translated_522_residues
MKFELNGKIIFSKEITDDAKKDIIEVLNDRTILLKGVPTGKEEEASKIVNYEFKGNELILNIISGTYARAHEAIIRLKKP
IMEKVGKIHKMGIRDIKIDNYEITINAPHNIDALENLKVPECETELNEEENTIKIIFKNIGDSELKRNIVDRAIKFVKTE
IDNIGDSGEECDLTYEVCGIAPNTIVSEYKAERTISYNKDPTEESEKLGWVKRFSGKGQWFYTPPMTKLLRAFEELLMEE
CINKIGFDECLFPKLIPLEVMYKMRYLEGLPEGMYYVSPPKRDPEMFKEFVNEMMIKNEIPIHKLKDLLRNPGYVLAPAQ
CEPFYQFFDHELVDIDNPVKFVDKSGWTYRWEGGGSKGLDRVHEFLRIETVQMGAPEFVNSVRDDTLKYAEKLAEKLDLE
YWTEVGDDPFYLEGRKKEERNIEFPEVPKYEMRLWLPHVKDERKGVAVTSANVHGTHFVEGFGVKDYKNRTVWTGCTGFG
LSRWVIGFLAQYGFDYNDWPELIKDKIGEMPNIPKVITWPKK
>Mature_522_residues
MKFELNGKIIFSKEITDDAKKDIIEVLNDRTILLKGVPTGKEEEASKIVNYEFKGNELILNIISGTYARAHEAIIRLKKP
IMEKVGKIHKMGIRDIKIDNYEITINAPHNIDALENLKVPECETELNEEENTIKIIFKNIGDSELKRNIVDRAIKFVKTE
IDNIGDSGEECDLTYEVCGIAPNTIVSEYKAERTISYNKDPTEESEKLGWVKRFSGKGQWFYTPPMTKLLRAFEELLMEE
CINKIGFDECLFPKLIPLEVMYKMRYLEGLPEGMYYVSPPKRDPEMFKEFVNEMMIKNEIPIHKLKDLLRNPGYVLAPAQ
CEPFYQFFDHELVDIDNPVKFVDKSGWTYRWEGGGSKGLDRVHEFLRIETVQMGAPEFVNSVRDDTLKYAEKLAEKLDLE
YWTEVGDDPFYLEGRKKEERNIEFPEVPKYEMRLWLPHVKDERKGVAVTSANVHGTHFVEGFGVKDYKNRTVWTGCTGFG
LSRWVIGFLAQYGFDYNDWPELIKDKIGEMPNIPKVITWPKK

Specific function: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)

COG id: COG0172

COG function: function code J; Seryl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYS2_META3 (A6UX37)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001325671.1
- ProteinModelPortal:   A6UX37
- SMR:   A6UX37
- STRING:   A6UX37
- GeneID:   5326589
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_1483
- eggNOG:   arNOG04799
- HOGENOM:   HBG542255
- OMA:   PAQCEPF
- ProtClustDB:   PRK00960
- BioCyc:   MAEO419665:MAEO_1483-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01278
- InterPro:   IPR002314
- InterPro:   IPR004503
- TIGRFAMs:   TIGR00415

Pfam domain/function: PF00587 tRNA-synt_2b

EC number: =6.1.1.11

Molecular weight: Translated: 60579; Mature: 60579

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: BINDING 319-319 BINDING 350-350 BINDING 483-483

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFELNGKIIFSKEITDDAKKDIIEVLNDRTILLKGVPTGKEEEASKIVNYEFKGNELIL
CEEEECCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHEEEEECCCEEEE
NIISGTYARAHEAIIRLKKPIMEKVGKIHKMGIRDIKIDNYEITINAPHNIDALENLKVP
EEHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEECCCCCCHHHCCCCC
ECETELNEEENTIKIIFKNIGDSELKRNIVDRAIKFVKTEIDNIGDSGEECDLTYEVCGI
CHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECC
APNTIVSEYKAERTISYNKDPTEESEKLGWVKRFSGKGQWFYTPPMTKLLRAFEELLMEE
CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHH
CINKIGFDECLFPKLIPLEVMYKMRYLEGLPEGMYYVSPPKRDPEMFKEFVNEMMIKNEI
HHHHCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCC
PIHKLKDLLRNPGYVLAPAQCEPFYQFFDHELVDIDNPVKFVDKSGWTYRWEGGGSKGLD
CHHHHHHHHCCCCEEEECCCCCHHHHHHCCHHCCCCCCHHHHCCCCCEEEECCCCCCCHH
RVHEFLRIETVQMGAPEFVNSVRDDTLKYAEKLAEKLDLEYWTEVGDDPFYLEGRKKEER
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCEEECCCCCCCC
NIEFPEVPKYEMRLWLPHVKDERKGVAVTSANVHGTHFVEGFGVKDYKNRTVWTGCTGFG
CCCCCCCCCHHHEEECCCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCEEEECCCCCC
LSRWVIGFLAQYGFDYNDWPELIKDKIGEMPNIPKVITWPKK
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKFELNGKIIFSKEITDDAKKDIIEVLNDRTILLKGVPTGKEEEASKIVNYEFKGNELIL
CEEEECCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHEEEEECCCEEEE
NIISGTYARAHEAIIRLKKPIMEKVGKIHKMGIRDIKIDNYEITINAPHNIDALENLKVP
EEHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEECCCCCCHHHCCCCC
ECETELNEEENTIKIIFKNIGDSELKRNIVDRAIKFVKTEIDNIGDSGEECDLTYEVCGI
CHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECC
APNTIVSEYKAERTISYNKDPTEESEKLGWVKRFSGKGQWFYTPPMTKLLRAFEELLMEE
CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHH
CINKIGFDECLFPKLIPLEVMYKMRYLEGLPEGMYYVSPPKRDPEMFKEFVNEMMIKNEI
HHHHCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCC
PIHKLKDLLRNPGYVLAPAQCEPFYQFFDHELVDIDNPVKFVDKSGWTYRWEGGGSKGLD
CHHHHHHHHCCCCEEEECCCCCHHHHHHCCHHCCCCCCHHHHCCCCCEEEECCCCCCCHH
RVHEFLRIETVQMGAPEFVNSVRDDTLKYAEKLAEKLDLEYWTEVGDDPFYLEGRKKEER
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCEEECCCCCCCC
NIEFPEVPKYEMRLWLPHVKDERKGVAVTSANVHGTHFVEGFGVKDYKNRTVWTGCTGFG
CCCCCCCCCHHHEEECCCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCEEEECCCCCC
LSRWVIGFLAQYGFDYNDWPELIKDKIGEMPNIPKVITWPKK
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA