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The map label for this gene is thiL [H]

Identifier: 150401877

GI number: 150401877

Start: 1514143

End: 1515126

Strand: Direct

Name: thiL [H]

Synonym: Maeo_1455

Alternate gene names: 150401877

Gene position: 1514143-1515126 (Clockwise)

Preceding gene: 150401874

Following gene: 150401878

Centisome position: 96.47

GC content: 28.86

Gene sequence:

>984_bases
ATGGACGAATTGAATATTATAAAAATAATACAAAATAATTTAAAATATAAAGGGAGCTCCCATGTGGTAAAATCAATAGG
TGATGATTGTGCCGTTGTAGGTATGGGCGAAAATAATTATTTAACAATAACTACGGATATGATGTTTAGGAGCTCCCATT
TTCCAAATATATTATCTCCATTTCAAATCGGGCATAGGGTTATAACGGCAAATCTTTCAGATATTGCTTCAATGGGAGCA
AAACCTTTGGGAATTGTAGTTTCTATGGGATTTAATAATCCCTCTAAAAAATTCATTGAGGAATTAACAAAAGGCATAAA
TTATGCAACAGAATTATATTGTTGCCCTATTATTGGGGGAGATACAAATAAATCAAAGGAATTAACATTATGTGGAACGG
CTTTTGGAATTGCCTCTAATCCATTATACCGATATAATGGAAATGTGGGCGACGATATAGTCATAACTAACGATATTGGG
AAAGTTTATTGTGCTTTTAAAATACTTGAAATGATTGAAACGGATAAAAAGCATAATAACCTTATTGAAGAATATAGTGA
AATTATGGAAAAATTATATATGCCCATTGCACAGGTGAAAATGGGATTACTATTAAATAAATATAATTATGCTTCTTCTT
GTTGCGATATATCGGATGGATTGGGAAAAGAATTATTTTATATGGGAAATTTTGAAGTAAAATCAAAAAAATTAATAAAT
GCCATGCCTAAAATTGTAATTGAATTTTGCAATAGATTTAATTTAAATCCTGTTGAGGTTGCTTTAAATAGTGGCGAAGA
GTGGGAGCTCCTATTTACCACAAATAAATATGATAAAATAAATAATATATTAAATAAATATGATAATACCAAAATAATAA
AACTAAAAAAGATAGGAAAAATAATAGATAAAGGGCATTATTTAGATGATGAAATACTCCATACTAGCGGTTATGTCCAT
AAATGGAGCGATAAAAATGAATAA

Upstream 100 bases:

>100_bases
GTCATAAGCGTAAAATAGCATACTACAATAAAACAGGTTTTGAAACTTGGTATATTTCCTATATATATCTATCATTGCTA
TTTTTCTCACTGGTGTATTT

Downstream 100 bases:

>100_bases
TTCAAAAACAAATATAAATAATAAATATATATTTTTAATAAAATTTTTTGTATTGTGTATATTATTTAATATATTGTTCC
TACCATTAAAGAATAGATTG

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MDELNIIKIIQNNLKYKGSSHVVKSIGDDCAVVGMGENNYLTITTDMMFRSSHFPNILSPFQIGHRVITANLSDIASMGA
KPLGIVVSMGFNNPSKKFIEELTKGINYATELYCCPIIGGDTNKSKELTLCGTAFGIASNPLYRYNGNVGDDIVITNDIG
KVYCAFKILEMIETDKKHNNLIEEYSEIMEKLYMPIAQVKMGLLLNKYNYASSCCDISDGLGKELFYMGNFEVKSKKLIN
AMPKIVIEFCNRFNLNPVEVALNSGEEWELLFTTNKYDKINNILNKYDNTKIIKLKKIGKIIDKGHYLDDEILHTSGYVH
KWSDKNE

Sequences:

>Translated_327_residues
MDELNIIKIIQNNLKYKGSSHVVKSIGDDCAVVGMGENNYLTITTDMMFRSSHFPNILSPFQIGHRVITANLSDIASMGA
KPLGIVVSMGFNNPSKKFIEELTKGINYATELYCCPIIGGDTNKSKELTLCGTAFGIASNPLYRYNGNVGDDIVITNDIG
KVYCAFKILEMIETDKKHNNLIEEYSEIMEKLYMPIAQVKMGLLLNKYNYASSCCDISDGLGKELFYMGNFEVKSKKLIN
AMPKIVIEFCNRFNLNPVEVALNSGEEWELLFTTNKYDKINNILNKYDNTKIIKLKKIGKIIDKGHYLDDEILHTSGYVH
KWSDKNE
>Mature_327_residues
MDELNIIKIIQNNLKYKGSSHVVKSIGDDCAVVGMGENNYLTITTDMMFRSSHFPNILSPFQIGHRVITANLSDIASMGA
KPLGIVVSMGFNNPSKKFIEELTKGINYATELYCCPIIGGDTNKSKELTLCGTAFGIASNPLYRYNGNVGDDIVITNDIG
KVYCAFKILEMIETDKKHNNLIEEYSEIMEKLYMPIAQVKMGLLLNKYNYASSCCDISDGLGKELFYMGNFEVKSKKLIN
AMPKIVIEFCNRFNLNPVEVALNSGEEWELLFTTNKYDKINNILNKYDNTKIIKLKKIGKIIDKGHYLDDEILHTSGYVH
KWSDKNE

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=263, Percent_Identity=25.8555133079848, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 36869; Mature: 36869

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDELNIIKIIQNNLKYKGSSHVVKSIGDDCAVVGMGENNYLTITTDMMFRSSHFPNILSP
CCCCCEEHHHHHCCCCCCCHHHHHHCCCCEEEEEECCCCEEEEEEHHHHHCCCCCCCCCH
FQIGHRVITANLSDIASMGAKPLGIVVSMGFNNPSKKFIEELTKGINYATELYCCPIIGG
HHHCCEEEEECHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHCCHHHHEEEEEEECC
DTNKSKELTLCGTAFGIASNPLYRYNGNVGDDIVITNDIGKVYCAFKILEMIETDKKHNN
CCCCCCEEEEEEEECCCCCCCEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHCCCHHHH
LIEEYSEIMEKLYMPIAQVKMGLLLNKYNYASSCCDISDGLGKELFYMGNFEVKSKKLIN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCEEEECCCEEHHHHHHH
AMPKIVIEFCNRFNLNPVEVALNSGEEWELLFTTNKYDKINNILNKYDNTKIIKLKKIGK
HHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEHHHHHH
IIDKGHYLDDEILHTSGYVHKWSDKNE
HHHCCCCCCHHHHHCCCCEEECCCCCC
>Mature Secondary Structure
MDELNIIKIIQNNLKYKGSSHVVKSIGDDCAVVGMGENNYLTITTDMMFRSSHFPNILSP
CCCCCEEHHHHHCCCCCCCHHHHHHCCCCEEEEEECCCCEEEEEEHHHHHCCCCCCCCCH
FQIGHRVITANLSDIASMGAKPLGIVVSMGFNNPSKKFIEELTKGINYATELYCCPIIGG
HHHCCEEEEECHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHCCHHHHEEEEEEECC
DTNKSKELTLCGTAFGIASNPLYRYNGNVGDDIVITNDIGKVYCAFKILEMIETDKKHNN
CCCCCCEEEEEEEECCCCCCCEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHCCCHHHH
LIEEYSEIMEKLYMPIAQVKMGLLLNKYNYASSCCDISDGLGKELFYMGNFEVKSKKLIN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCEEEECCCEEHHHHHHH
AMPKIVIEFCNRFNLNPVEVALNSGEEWELLFTTNKYDKINNILNKYDNTKIIKLKKIGK
HHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEHHHHHH
IIDKGHYLDDEILHTSGYVHKWSDKNE
HHHCCCCCCHHHHHCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]