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The map label for this gene is glyS [H]

Identifier: 150401716

GI number: 150401716

Start: 1352789

End: 1354528

Strand: Reverse

Name: glyS [H]

Synonym: Maeo_1294

Alternate gene names: 150401716

Gene position: 1354528-1352789 (Counterclockwise)

Preceding gene: 150401717

Following gene: 150401714

Centisome position: 86.3

GC content: 32.87

Gene sequence:

>1740_bases
ATGGAAACTCCAAACACAAAAGACAAATATGAAAAAGTTATGGATTTGGCAAAAAGAAGAGGATATTTATGGAGCTCCTT
TGAAATTTATGGTGGTATAGCCGGATTTGTAGATTATGCCCCATTAGGAGCAATGTTAAAAAATAACATCATAGACACAT
GGAGAAAACATTATATTACAAATGAGGAATTTTACGAAATAGATTGCCCTACAATAACCCCCCACGATGTTTTAAAAGCT
TCTGGGCATGTGGATAACTTTACAGACCCTATGATAGAATGTAAAGAATGTTTAGAATCATACAGGGCAGACCATATAAT
AGAGGAAAATATTGATATAGATACAGAGGGCAAAACCTTAGAGGAATTACAACAATTAATGGAGACTCACAAAATCACAT
GCCCAAAATGTAGCGGACAATTTGGAGAGGTTAAAAGCTATAATTTAATGTTCCTTACTTCAATAGGCCCAAGTGGAAAT
AGAATAGGATATATGAGACCAGAAACAGCACAGGGAATATTTATTCAATTTAGAAGATTATCACAGTTTTTTAGAAATAA
ACTTCCTTTTGGAGTTGCACAAATTGGAAAAGCATACAGAAATGAGATTTCACCAAGGCAGGGAGTAATTAGATTAAGAG
AATTTACACAGGCAGAGGCGGAATTTTTCGTGCATCCTACAATAAAGGAGCATAAGAAATTTAAAGAAGTTGAAAATGAT
GTAATACCCCTATTACCTGCAAGTAGGCAAATGGACGAATCATTGCCAAAAGATGAAAAAGTAATAAATATGTCTTTAAA
AGATGCCGTAGAAAATAATATTATTAGGCATGAAACAATTGCATATTTTGTAGCAATTACAAAAAGGTTTTTGTTGGATA
TAGGTATTGACAGCTCCAAATTAAGATTTAGACAGCATTTACCAGATGAAATGGCACATTATGCTATTGACTGTTGGGAT
GCCGAAATATACACAGATAGATTTGGCTGGATTGAGTGTGTAGGTATCGCCGATAGAACAGATTTTGACTTAAAAGCACA
TATGGAGAACAGCGGTGTAGATTTAAGCATATTTGTAGAATATGACGAACCAAAGGAAATTGAGACCTACGAAATAGAAT
TAAATTATAAAGTTGTGGGCAAAGTATTTAAAAAAGATATGAAATTAGTAAGCGATGCCTTAAATGAATTAGATAATAAT
GAAATGGAAAAATTAGTAAATACCATTAAAAATGGAGAAGAATATATATTAAAAGTAGGAGATAAAGAATTTACAATATT
GGAGGACTATTTAACGGCTAAAAAAGTTCAAAAGAAAGTTATGGGGGAGAAAGTTTTACCTCATGTTATTGAGCCATCTC
ATGGAATAGATAGAATTACATTCTGTTTGTTGGAACATTCCTTTAATGAGGAAGAGGATAGAACCTATTTAAGTATTAAT
CCAACAGTATCACCGATTAAAGTTGGTGTATTCCCATTAGTTAATAAACAAGGTATGCCTGAAATTGCCATGGATATAAA
GAACAATTTAAGAAAAAACGGAATTCTTGCAGAATATGATGACAGCGGAGCAATAGGAAGAAGATATATGAGAATGGACG
AGGTAGGAGCTCCCTTCTGTATTACAGTAGATGGTCAAACCTTAGAGGATAACACCATCACCATAAGGGAAAGAGATTCC
AGAGAGCAAATTAGAATAAAAATAGAGGAAGTTGTAGATTATATTAAAAACAAATTATAA

Upstream 100 bases:

>100_bases
TATAGATAAAATAAATAATATATAATGTAGGGCATATAATGTAATCATAATATAATATATACCCATATTAAAAAATCATA
TATTAAAAAATGGTGATTAA

Downstream 100 bases:

>100_bases
TAGGTTATTAATGAATTAATTTATTATTTCTTTTTTTGTTTTTATTTATTAAAATAAAATCCTTGTTTTGTACCTCTTTT
TTTCAATTCATTTGATATTT

Product: glycyl-tRNA synthetase

Products: NA

Alternate protein names: Glycine--tRNA ligase; GlyRS [H]

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
METPNTKDKYEKVMDLAKRRGYLWSSFEIYGGIAGFVDYAPLGAMLKNNIIDTWRKHYITNEEFYEIDCPTITPHDVLKA
SGHVDNFTDPMIECKECLESYRADHIIEENIDIDTEGKTLEELQQLMETHKITCPKCSGQFGEVKSYNLMFLTSIGPSGN
RIGYMRPETAQGIFIQFRRLSQFFRNKLPFGVAQIGKAYRNEISPRQGVIRLREFTQAEAEFFVHPTIKEHKKFKEVEND
VIPLLPASRQMDESLPKDEKVINMSLKDAVENNIIRHETIAYFVAITKRFLLDIGIDSSKLRFRQHLPDEMAHYAIDCWD
AEIYTDRFGWIECVGIADRTDFDLKAHMENSGVDLSIFVEYDEPKEIETYEIELNYKVVGKVFKKDMKLVSDALNELDNN
EMEKLVNTIKNGEEYILKVGDKEFTILEDYLTAKKVQKKVMGEKVLPHVIEPSHGIDRITFCLLEHSFNEEEDRTYLSIN
PTVSPIKVGVFPLVNKQGMPEIAMDIKNNLRKNGILAEYDDSGAIGRRYMRMDEVGAPFCITVDGQTLEDNTITIRERDS
REQIRIKIEEVVDYIKNKL

Sequences:

>Translated_579_residues
METPNTKDKYEKVMDLAKRRGYLWSSFEIYGGIAGFVDYAPLGAMLKNNIIDTWRKHYITNEEFYEIDCPTITPHDVLKA
SGHVDNFTDPMIECKECLESYRADHIIEENIDIDTEGKTLEELQQLMETHKITCPKCSGQFGEVKSYNLMFLTSIGPSGN
RIGYMRPETAQGIFIQFRRLSQFFRNKLPFGVAQIGKAYRNEISPRQGVIRLREFTQAEAEFFVHPTIKEHKKFKEVEND
VIPLLPASRQMDESLPKDEKVINMSLKDAVENNIIRHETIAYFVAITKRFLLDIGIDSSKLRFRQHLPDEMAHYAIDCWD
AEIYTDRFGWIECVGIADRTDFDLKAHMENSGVDLSIFVEYDEPKEIETYEIELNYKVVGKVFKKDMKLVSDALNELDNN
EMEKLVNTIKNGEEYILKVGDKEFTILEDYLTAKKVQKKVMGEKVLPHVIEPSHGIDRITFCLLEHSFNEEEDRTYLSIN
PTVSPIKVGVFPLVNKQGMPEIAMDIKNNLRKNGILAEYDDSGAIGRRYMRMDEVGAPFCITVDGQTLEDNTITIRERDS
REQIRIKIEEVVDYIKNKL
>Mature_579_residues
METPNTKDKYEKVMDLAKRRGYLWSSFEIYGGIAGFVDYAPLGAMLKNNIIDTWRKHYITNEEFYEIDCPTITPHDVLKA
SGHVDNFTDPMIECKECLESYRADHIIEENIDIDTEGKTLEELQQLMETHKITCPKCSGQFGEVKSYNLMFLTSIGPSGN
RIGYMRPETAQGIFIQFRRLSQFFRNKLPFGVAQIGKAYRNEISPRQGVIRLREFTQAEAEFFVHPTIKEHKKFKEVEND
VIPLLPASRQMDESLPKDEKVINMSLKDAVENNIIRHETIAYFVAITKRFLLDIGIDSSKLRFRQHLPDEMAHYAIDCWD
AEIYTDRFGWIECVGIADRTDFDLKAHMENSGVDLSIFVEYDEPKEIETYEIELNYKVVGKVFKKDMKLVSDALNELDNN
EMEKLVNTIKNGEEYILKVGDKEFTILEDYLTAKKVQKKVMGEKVLPHVIEPSHGIDRITFCLLEHSFNEEEDRTYLSIN
PTVSPIKVGVFPLVNKQGMPEIAMDIKNNLRKNGILAEYDDSGAIGRRYMRMDEVGAPFCITVDGQTLEDNTITIRERDS
REQIRIKIEEVVDYIKNKL

Specific function: Catalyzes the attachment of glycine to tRNA(Gly) [H]

COG id: COG0423

COG function: function code J; Glycyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI116805340, Length=597, Percent_Identity=40.7035175879397, Blast_Score=446, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17554996, Length=586, Percent_Identity=40.7849829351536, Blast_Score=453, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI32564541, Length=586, Percent_Identity=40.7849829351536, Blast_Score=452, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6325338, Length=601, Percent_Identity=40.765391014975, Blast_Score=453, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6319597, Length=636, Percent_Identity=38.2075471698113, Blast_Score=436, Evalue=1e-123,
Organism=Drosophila melanogaster, GI21357965, Length=580, Percent_Identity=41.7241379310345, Blast_Score=459, Evalue=1e-129,
Organism=Drosophila melanogaster, GI24664462, Length=580, Percent_Identity=41.7241379310345, Blast_Score=459, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR022960
- InterPro:   IPR002315 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.14 [H]

Molecular weight: Translated: 66950; Mature: 66950

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METPNTKDKYEKVMDLAKRRGYLWSSFEIYGGIAGFVDYAPLGAMLKNNIIDTWRKHYIT
CCCCCCHHHHHHHHHHHHHCCCEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NEEFYEIDCPTITPHDVLKASGHVDNFTDPMIECKECLESYRADHIIEENIDIDTEGKTL
CCCEEEECCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCHH
EELQQLMETHKITCPKCSGQFGEVKSYNLMFLTSIGPSGNRIGYMRPETAQGIFIQFRRL
HHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCHHHHHHHHH
SQFFRNKLPFGVAQIGKAYRNEISPRQGVIRLREFTQAEAEFFVHPTIKEHKKFKEVEND
HHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHCC
VIPLLPASRQMDESLPKDEKVINMSLKDAVENNIIRHETIAYFVAITKRFLLDIGIDSSK
CCCCCCCCHHHHHHCCCCHHEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHH
LRFRQHLPDEMAHYAIDCWDAEIYTDRFGWIECVGIADRTDFDLKAHMENSGVDLSIFVE
HHHHHCCCHHHHHHHHEEECCEEEECCCCCEEEEEECCCCCCCEEEECCCCCCEEEEEEE
YDEPKEIETYEIELNYKVVGKVFKKDMKLVSDALNELDNNEMEKLVNTIKNGEEYILKVG
ECCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEC
DKEFTILEDYLTAKKVQKKVMGEKVLPHVIEPSHGIDRITFCLLEHSFNEEEDRTYLSIN
CCCEEHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEC
PTVSPIKVGVFPLVNKQGMPEIAMDIKNNLRKNGILAEYDDSGAIGRRYMRMDEVGAPFC
CCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCEE
ITVDGQTLEDNTITIRERDSREQIRIKIEEVVDYIKNKL
EEECCCEECCCEEEEEECCCCHHHHEEHHHHHHHHHHCC
>Mature Secondary Structure
METPNTKDKYEKVMDLAKRRGYLWSSFEIYGGIAGFVDYAPLGAMLKNNIIDTWRKHYIT
CCCCCCHHHHHHHHHHHHHCCCEEECHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NEEFYEIDCPTITPHDVLKASGHVDNFTDPMIECKECLESYRADHIIEENIDIDTEGKTL
CCCEEEECCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCHH
EELQQLMETHKITCPKCSGQFGEVKSYNLMFLTSIGPSGNRIGYMRPETAQGIFIQFRRL
HHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCHHHHHHHHH
SQFFRNKLPFGVAQIGKAYRNEISPRQGVIRLREFTQAEAEFFVHPTIKEHKKFKEVEND
HHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHCC
VIPLLPASRQMDESLPKDEKVINMSLKDAVENNIIRHETIAYFVAITKRFLLDIGIDSSK
CCCCCCCCHHHHHHCCCCHHEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHH
LRFRQHLPDEMAHYAIDCWDAEIYTDRFGWIECVGIADRTDFDLKAHMENSGVDLSIFVE
HHHHHCCCHHHHHHHHEEECCEEEECCCCCEEEEEECCCCCCCEEEECCCCCCEEEEEEE
YDEPKEIETYEIELNYKVVGKVFKKDMKLVSDALNELDNNEMEKLVNTIKNGEEYILKVG
ECCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEC
DKEFTILEDYLTAKKVQKKVMGEKVLPHVIEPSHGIDRITFCLLEHSFNEEEDRTYLSIN
CCCEEHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEC
PTVSPIKVGVFPLVNKQGMPEIAMDIKNNLRKNGILAEYDDSGAIGRRYMRMDEVGAPFC
CCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCEE
ITVDGQTLEDNTITIRERDSREQIRIKIEEVVDYIKNKL
EEECCCEECCCEEEEEECCCCHHHHEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA