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The map label for this gene is pheS [H]

Identifier: 150401714

GI number: 150401714

Start: 1350040

End: 1351581

Strand: Reverse

Name: pheS [H]

Synonym: Maeo_1292

Alternate gene names: 150401714

Gene position: 1351581-1350040 (Counterclockwise)

Preceding gene: 150401716

Following gene: 150401713

Centisome position: 86.12

GC content: 30.74

Gene sequence:

>1542_bases
ATGGAAGATTTTAAACTACACAATGACGAGAAAAAACTTTTAAAAATATTTCAAGAGGCATATGACAATAAAAATATTAC
AAAATTATCTGTTGAGGGATTAGCAAAAAATGAGCTAATGGGCTCGGAAACAAAGGTAATGAGAACGGCTCTTTGGTTAT
CTGCGGAAGATAAAAAATTAGTTAATATTATCGAAAATAAATCAAAAATTGCCAAATTAACGGAGGAAGGAAAAAAAGTA
GTAGAAAAAGGACTTCCAGAGCGACAGGTTGCAAATTATATGATTGAAAATGATTTAAAAAATATCCCAATTAAAGAATT
AGGCAATATTTTAGACAAATCAGAAGTAAATCCTGCATTAGGCAATTTAAAAAAGAAAAAAATAGCTAAAATAGAAAAAG
GAAATATAATAATTGAAAATTTGCAGTATGAAGATAAAGAAGAAAATACATTAAACAAAATAAAAATAAATGAAGAAAAC
AAAAACAGCGATTTAAATAACTACAATGACGAAGAAAAGAAATTAATAAATAATCTCCAAAAAAGAGGATTTATAGCAAT
TGAGGAAGAAGTAGATAGAGCAATAGAATTAACGGAAAAAGGTATTGAATTTATAAAAAACAACATCATTGAGATAAAAG
AAGAAATATCCCAACTAACAAGGGAGCATATTGTAAGTGGGAAATGGAAAGATTGCCACATTAGACCATATGATGCAAAA
ATACCATCAGAGGAAGTATATCCTGCTAAATTACACCCTATGACACGAATTATAAATGATGTTAAAGAGGTATTAATTGG
AATGGGATTTAAAGAGGTAAAAAATCCAATTGTAGAAACAGAATTCTGGAATTTTGATGTTTTATTTGAACCGCAAGACC
ATCCTGCAAGAGATATGCAAGATACATTCTTTTTAAGATACCCAAATAAAGGAGAAATACCTGAAATGGTAAAGGATATT
AAATCAATACATGAAAAAGGAATGGTAGGAGATAAAAAAATATCAAAAGGCTGGAGATATGAATTTGATGAAGAAATATC
CAAAAAAACAGTATTAAGAACCCATACAACAGTATCATCAATAAAATATTTAGCCTCATTAACAGATGAAGAAAAAGAAA
AACCCCATAAAATATTTAGCATAGATAGAGTATTTAGAAATGAGGCAATAGATTATAGTCATTTGCCTGAGTTTTATCAG
TGTGAGGGCATAATATTAGCCGAGGGTGTGCATTTTGACAATTTAATTGGATTATTAAAAGAATTTTTAAATAGATTAGG
ATTTGAACAGGTGAGAATTAGACCTGCATACTTCCCATTCACAGAACCATCATTGGAAGCCGAGGTATTCGTAGAGGGCA
GAGGTTGGTTGGAGCTCCTTGGTGCGGGAGTATTTAGGCCCGAAGTAGTAGAGCCATTGGGAATAAATAAACCAGTTTTG
GCATGGGGAATTGGATTAAGTAGATTGGCAATGTTAAGATGGGGATTAACAGATATTAGGGAGCTCCATAAAAATGAATT
AAATTGGTTGAAAAAGGCATAG

Upstream 100 bases:

>100_bases
TTCGTTATGATTAATTATATTAAATATAGTTATTATATCAATTATTATTATAAAATAGGACTAATAACATATTAATATAT
TTTATATATTTGGTGAAGCT

Downstream 100 bases:

>100_bases
TATAAAATATTATAGTTAATATTCATAACTGTAAAGAGAGAAATAATGAACAACAACAAAATAATAAAAGATGCATATTT
GGAGTCCATAACTAATAAAA

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MEDFKLHNDEKKLLKIFQEAYDNKNITKLSVEGLAKNELMGSETKVMRTALWLSAEDKKLVNIIENKSKIAKLTEEGKKV
VEKGLPERQVANYMIENDLKNIPIKELGNILDKSEVNPALGNLKKKKIAKIEKGNIIIENLQYEDKEENTLNKIKINEEN
KNSDLNNYNDEEKKLINNLQKRGFIAIEEEVDRAIELTEKGIEFIKNNIIEIKEEISQLTREHIVSGKWKDCHIRPYDAK
IPSEEVYPAKLHPMTRIINDVKEVLIGMGFKEVKNPIVETEFWNFDVLFEPQDHPARDMQDTFFLRYPNKGEIPEMVKDI
KSIHEKGMVGDKKISKGWRYEFDEEISKKTVLRTHTTVSSIKYLASLTDEEKEKPHKIFSIDRVFRNEAIDYSHLPEFYQ
CEGIILAEGVHFDNLIGLLKEFLNRLGFEQVRIRPAYFPFTEPSLEAEVFVEGRGWLELLGAGVFRPEVVEPLGINKPVL
AWGIGLSRLAMLRWGLTDIRELHKNELNWLKKA

Sequences:

>Translated_513_residues
MEDFKLHNDEKKLLKIFQEAYDNKNITKLSVEGLAKNELMGSETKVMRTALWLSAEDKKLVNIIENKSKIAKLTEEGKKV
VEKGLPERQVANYMIENDLKNIPIKELGNILDKSEVNPALGNLKKKKIAKIEKGNIIIENLQYEDKEENTLNKIKINEEN
KNSDLNNYNDEEKKLINNLQKRGFIAIEEEVDRAIELTEKGIEFIKNNIIEIKEEISQLTREHIVSGKWKDCHIRPYDAK
IPSEEVYPAKLHPMTRIINDVKEVLIGMGFKEVKNPIVETEFWNFDVLFEPQDHPARDMQDTFFLRYPNKGEIPEMVKDI
KSIHEKGMVGDKKISKGWRYEFDEEISKKTVLRTHTTVSSIKYLASLTDEEKEKPHKIFSIDRVFRNEAIDYSHLPEFYQ
CEGIILAEGVHFDNLIGLLKEFLNRLGFEQVRIRPAYFPFTEPSLEAEVFVEGRGWLELLGAGVFRPEVVEPLGINKPVL
AWGIGLSRLAMLRWGLTDIRELHKNELNWLKKA
>Mature_513_residues
MEDFKLHNDEKKLLKIFQEAYDNKNITKLSVEGLAKNELMGSETKVMRTALWLSAEDKKLVNIIENKSKIAKLTEEGKKV
VEKGLPERQVANYMIENDLKNIPIKELGNILDKSEVNPALGNLKKKKIAKIEKGNIIIENLQYEDKEENTLNKIKINEEN
KNSDLNNYNDEEKKLINNLQKRGFIAIEEEVDRAIELTEKGIEFIKNNIIEIKEEISQLTREHIVSGKWKDCHIRPYDAK
IPSEEVYPAKLHPMTRIINDVKEVLIGMGFKEVKNPIVETEFWNFDVLFEPQDHPARDMQDTFFLRYPNKGEIPEMVKDI
KSIHEKGMVGDKKISKGWRYEFDEEISKKTVLRTHTTVSSIKYLASLTDEEKEKPHKIFSIDRVFRNEAIDYSHLPEFYQ
CEGIILAEGVHFDNLIGLLKEFLNRLGFEQVRIRPAYFPFTEPSLEAEVFVEGRGWLELLGAGVFRPEVVEPLGINKPVL
AWGIGLSRLAMLRWGLTDIRELHKNELNWLKKA

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758340, Length=340, Percent_Identity=39.1176470588235, Blast_Score=251, Evalue=1e-66,
Organism=Escherichia coli, GI1788007, Length=281, Percent_Identity=34.5195729537367, Blast_Score=159, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI32563657, Length=449, Percent_Identity=32.9621380846325, Blast_Score=244, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI17508957, Length=449, Percent_Identity=32.9621380846325, Blast_Score=243, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI32566635, Length=284, Percent_Identity=26.7605633802817, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6321087, Length=464, Percent_Identity=33.4051724137931, Blast_Score=256, Evalue=8e-69,
Organism=Drosophila melanogaster, GI18858079, Length=453, Percent_Identity=31.5673289183223, Blast_Score=220, Evalue=2e-57,
Organism=Drosophila melanogaster, GI17137424, Length=292, Percent_Identity=23.2876712328767, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR022917
- InterPro:   IPR002319 [H]

Pfam domain/function: PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 59540; Mature: 59540

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDFKLHNDEKKLLKIFQEAYDNKNITKLSVEGLAKNELMGSETKVMRTALWLSAEDKKL
CCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCHHHHHHHHHHHCCCCHHH
VNIIENKSKIAKLTEEGKKVVEKGLPERQVANYMIENDLKNIPIKELGNILDKSEVNPAL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHH
GNLKKKKIAKIEKGNIIIENLQYEDKEENTLNKIKINEENKNSDLNNYNDEEKKLINNLQ
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHH
KRGFIAIEEEVDRAIELTEKGIEFIKNNIIEIKEEISQLTREHIVSGKWKDCHIRPYDAK
HCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
IPSEEVYPAKLHPMTRIINDVKEVLIGMGFKEVKNPIVETEFWNFDVLFEPQDHPARDMQ
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCEEEEECCCCCCCCCCC
DTFFLRYPNKGEIPEMVKDIKSIHEKGMVGDKKISKGWRYEFDEEISKKTVLRTHTTVSS
CEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
IKYLASLTDEEKEKPHKIFSIDRVFRNEAIDYSHLPEFYQCEGIILAEGVHFDNLIGLLK
HHHHHHHCHHHHHCCHHHHHHHHHHHHCCCCHHHCCHHHHCCCEEEECCCCHHHHHHHHH
EFLNRLGFEQVRIRPAYFPFTEPSLEAEVFVEGRGWLELLGAGVFRPEVVEPLGINKPVL
HHHHHCCCHHEEEEECCCCCCCCCCCEEEEECCCCHHHHHHCCCCCCHHCCCCCCCCCHH
AWGIGLSRLAMLRWGLTDIRELHKNELNWLKKA
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEDFKLHNDEKKLLKIFQEAYDNKNITKLSVEGLAKNELMGSETKVMRTALWLSAEDKKL
CCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCHHHHHHHHHHHCCCCHHH
VNIIENKSKIAKLTEEGKKVVEKGLPERQVANYMIENDLKNIPIKELGNILDKSEVNPAL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHH
GNLKKKKIAKIEKGNIIIENLQYEDKEENTLNKIKINEENKNSDLNNYNDEEKKLINNLQ
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHH
KRGFIAIEEEVDRAIELTEKGIEFIKNNIIEIKEEISQLTREHIVSGKWKDCHIRPYDAK
HCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
IPSEEVYPAKLHPMTRIINDVKEVLIGMGFKEVKNPIVETEFWNFDVLFEPQDHPARDMQ
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCEEEEECCCCCCCCCCC
DTFFLRYPNKGEIPEMVKDIKSIHEKGMVGDKKISKGWRYEFDEEISKKTVLRTHTTVSS
CEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
IKYLASLTDEEKEKPHKIFSIDRVFRNEAIDYSHLPEFYQCEGIILAEGVHFDNLIGLLK
HHHHHHHCHHHHHCCHHHHHHHHHHHHCCCCHHHCCHHHHCCCEEEECCCCHHHHHHHHH
EFLNRLGFEQVRIRPAYFPFTEPSLEAEVFVEGRGWLELLGAGVFRPEVVEPLGINKPVL
HHHHHCCCHHEEEEECCCCCCCCCCCEEEEECCCCHHHHHHCCCCCCHHCCCCCCCCCHH
AWGIGLSRLAMLRWGLTDIRELHKNELNWLKKA
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA