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The map label for this gene is cobC [H]

Identifier: 150401266

GI number: 150401266

Start: 867085

End: 867744

Strand: Reverse

Name: cobC [H]

Synonym: Maeo_0838

Alternate gene names: 150401266

Gene position: 867744-867085 (Counterclockwise)

Preceding gene: 150401268

Following gene: 150401262

Centisome position: 55.29

GC content: 25.61

Gene sequence:

>660_bases
ATGGAAATATCAAATAATATTAAAATTTATTTAATGAGGCATGGGGAGACAGATGCAGGAAATGATATTTTTGTTGGCGT
AACCGATGCAAATTTAACTGAAAAAGGAATTAGCCAAACAAAACAAATGGCAAAATTTTTTATTGACAAACCAATTAAAG
AAATATATTCAAGTCAATTAAAACGAGCAAGGCACACCGCAGAAATTATTAAAGAGGTAATATGTTCCAACAAAGAAAAT
GATATTCCACTATATCAATGTGATTTACTAGCTGAAATGGATTTTGGAGAGTGGGAAAAAATGAATAGAAAAGATATTAA
AGAAAAATATAAAGAATTATATAAAAAATGGGAAGAAAATCCTTCAAAAAATACTCCGCCAAAAGCAGGAGCTCCCCAAA
ATGTTGCAAAAAATATGGTAAAATTTTTGGATAAAATATACAATAAATTTAAAAAAGATGCTGAAAATGGAAACAATATA
GAAATTATTGCAGTTTCCCATAAAACAGCAATAAGGATATTATTATGTTATTTAGATAATAAAGATTTAAAATATTATCG
GAGCTATAAAATTAATGAAGGAGATATATTTGAAATAAATTATACCAATAACGGTTGGAAATGGAAAAAAATTAATATAT
TAAATAGTATAAATAATTAG

Upstream 100 bases:

>100_bases
GAATATGACATATATACAAAATATAAGGGGCGATATTATATGCTAAAAATCACAGATTTTTAGACTAATATCACCTAAAA
ATAAAAACACCGGTGATATT

Downstream 100 bases:

>100_bases
TTTCAAAATACATCATTTAAAAATTTTTTAAATTCCTCAAATGCTTTTTTTCTATGGGAAATATTGCTTTTTTCCTCTGT
TTTCATTTCTGCAAATGTTC

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MEISNNIKIYLMRHGETDAGNDIFVGVTDANLTEKGISQTKQMAKFFIDKPIKEIYSSQLKRARHTAEIIKEVICSNKEN
DIPLYQCDLLAEMDFGEWEKMNRKDIKEKYKELYKKWEENPSKNTPPKAGAPQNVAKNMVKFLDKIYNKFKKDAENGNNI
EIIAVSHKTAIRILLCYLDNKDLKYYRSYKINEGDIFEINYTNNGWKWKKINILNSINN

Sequences:

>Translated_219_residues
MEISNNIKIYLMRHGETDAGNDIFVGVTDANLTEKGISQTKQMAKFFIDKPIKEIYSSQLKRARHTAEIIKEVICSNKEN
DIPLYQCDLLAEMDFGEWEKMNRKDIKEKYKELYKKWEENPSKNTPPKAGAPQNVAKNMVKFLDKIYNKFKKDAENGNNI
EIIAVSHKTAIRILLCYLDNKDLKYYRSYKINEGDIFEINYTNNGWKWKKINILNSINN
>Mature_219_residues
MEISNNIKIYLMRHGETDAGNDIFVGVTDANLTEKGISQTKQMAKFFIDKPIKEIYSSQLKRARHTAEIIKEVICSNKEN
DIPLYQCDLLAEMDFGEWEKMNRKDIKEKYKELYKKWEENPSKNTPPKAGAPQNVAKNMVKFLDKIYNKFKKDAENGNNI
EIIAVSHKTAIRILLCYLDNKDLKYYRSYKINEGDIFEINYTNNGWKWKKINILNSINN

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=211, Percent_Identity=23.2227488151659, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 25643; Mature: 25643

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEISNNIKIYLMRHGETDAGNDIFVGVTDANLTEKGISQTKQMAKFFIDKPIKEIYSSQL
CCCCCCEEEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRARHTAEIIKEVICSNKENDIPLYQCDLLAEMDFGEWEKMNRKDIKEKYKELYKKWEEN
HHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHCC
PSKNTPPKAGAPQNVAKNMVKFLDKIYNKFKKDAENGNNIEIIAVSHKTAIRILLCYLDN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHEEEEEEEEECC
KDLKYYRSYKINEGDIFEINYTNNGWKWKKINILNSINN
CCCHHHHEEECCCCCEEEEEECCCCEEEEEEEHHHCCCC
>Mature Secondary Structure
MEISNNIKIYLMRHGETDAGNDIFVGVTDANLTEKGISQTKQMAKFFIDKPIKEIYSSQL
CCCCCCEEEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRARHTAEIIKEVICSNKENDIPLYQCDLLAEMDFGEWEKMNRKDIKEKYKELYKKWEEN
HHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHCC
PSKNTPPKAGAPQNVAKNMVKFLDKIYNKFKKDAENGNNIEIIAVSHKTAIRILLCYLDN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHEEEEEEEEECC
KDLKYYRSYKINEGDIFEINYTNNGWKWKKINILNSINN
CCCHHHHEEECCCCCEEEEEECCCCEEEEEEEHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]