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The map label for this gene is gch3 [H]

Identifier: 150401247

GI number: 150401247

Start: 847584

End: 848402

Strand: Reverse

Name: gch3 [H]

Synonym: Maeo_0818

Alternate gene names: 150401247

Gene position: 848402-847584 (Counterclockwise)

Preceding gene: 150401248

Following gene: 150401246

Centisome position: 54.06

GC content: 31.99

Gene sequence:

>819_bases
ATGATTCAGATAACGATTATACAAATAGATAATTATGGACCTTGGACAGTTACTCCAAATCCCAGAAGGGAAAGTGATTT
GCAGGCATTGCAATCACGACTATATAGTGATTTAAATTTACAGTTTGGAGCTCATAAAGGATTGGTATTTTATACTAGAT
TTGACAATCTTATGGCTATTACCAATGGTATTGACACGGAGACACATAAGAGAATACAAGATAGTATTAAAAATAGATAT
CCTTTTACTGTTAGTATGGCATCTGGGGTTGCGGAAACTCCTTATGAAGCACAGAAAATTGCAACTGCAAAAATTCAAAA
TAAAGGAAGTGCCCAAGATAAATATAGGACTGAAATATTAGATATTGAAGAATTGGATAATTCAATAGAAAATACTGTGA
CACTTGCCCATGTTGATATAAATGACATCACTGGAACGCTAACAGATTTAGAAAATGCTTATGACACATATGTTAGTGTT
AATGAAGTTCATTTAGCACTGATTAAAGAACTAAAAAAATATAATGCAATGGGATTCTTTATTGGCGGAGATAATTTTAT
GGCCCCATGTAATGGAATGACAGAAGAAGATTTTTTAGAGATGTTTGAAAATATTAAAAATTCAACAGGAATTGATTTAA
AAGCAGGAATTGGAATTGGTAAAACTGCCGAAGATGCTTCAAATATGGCAGATATTGGATTGGAATTAATAAGGGACAAA
AAAACGGCTACTCAGGTATATACATTAAATTATGAAGAATATGCCGTAGGCAATATAGTAAATCAACGGACATTAGGAGT
AAATATGGATTGCAAATAA

Upstream 100 bases:

>100_bases
TAATTAATAAGTATTAAATATATGCCCCATAATTATTATTTTTATAATATATTATTATTTATGGGATTAAGTCAATTGCT
AAAATAACAATGATGATATC

Downstream 100 bases:

>100_bases
TATTATTATATTATTATATACGCCACCCATACAATTTTGATAAAATGTATAATAAAAATAATAAAAATAATAATTTGTTG
AATTTAAAGAATAAAATAAG

Product: GTP cyclohydrolase III

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MIQITIIQIDNYGPWTVTPNPRRESDLQALQSRLYSDLNLQFGAHKGLVFYTRFDNLMAITNGIDTETHKRIQDSIKNRY
PFTVSMASGVAETPYEAQKIATAKIQNKGSAQDKYRTEILDIEELDNSIENTVTLAHVDINDITGTLTDLENAYDTYVSV
NEVHLALIKELKKYNAMGFFIGGDNFMAPCNGMTEEDFLEMFENIKNSTGIDLKAGIGIGKTAEDASNMADIGLELIRDK
KTATQVYTLNYEEYAVGNIVNQRTLGVNMDCK

Sequences:

>Translated_272_residues
MIQITIIQIDNYGPWTVTPNPRRESDLQALQSRLYSDLNLQFGAHKGLVFYTRFDNLMAITNGIDTETHKRIQDSIKNRY
PFTVSMASGVAETPYEAQKIATAKIQNKGSAQDKYRTEILDIEELDNSIENTVTLAHVDINDITGTLTDLENAYDTYVSV
NEVHLALIKELKKYNAMGFFIGGDNFMAPCNGMTEEDFLEMFENIKNSTGIDLKAGIGIGKTAEDASNMADIGLELIRDK
KTATQVYTLNYEEYAVGNIVNQRTLGVNMDCK
>Mature_272_residues
MIQITIIQIDNYGPWTVTPNPRRESDLQALQSRLYSDLNLQFGAHKGLVFYTRFDNLMAITNGIDTETHKRIQDSIKNRY
PFTVSMASGVAETPYEAQKIATAKIQNKGSAQDKYRTEILDIEELDNSIENTVTLAHVDINDITGTLTDLENAYDTYVSV
NEVHLALIKELKKYNAMGFFIGGDNFMAPCNGMTEEDFLEMFENIKNSTGIDLKAGIGIGKTAEDASNMADIGLELIRDK
KTATQVYTLNYEEYAVGNIVNQRTLGVNMDCK

Specific function: Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity [H]

COG id: COG2429

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal-type GTP cyclohydrolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007839
- ProDom:   PD313320 [H]

Pfam domain/function: PF05165 GGDN [H]

EC number: =3.5.4.29 [H]

Molecular weight: Translated: 30464; Mature: 30464

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQITIIQIDNYGPWTVTPNPRRESDLQALQSRLYSDLNLQFGAHKGLVFYTRFDNLMAI
CEEEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCEEEE
TNGIDTETHKRIQDSIKNRYPFTVSMASGVAETPYEAQKIATAKIQNKGSAQDKYRTEIL
ECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHC
DIEELDNSIENTVTLAHVDINDITGTLTDLENAYDTYVSVNEVHLALIKELKKYNAMGFF
CHHHHCCHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHCCCCEEE
IGGDNFMAPCNGMTEEDFLEMFENIKNSTGIDLKAGIGIGKTAEDASNMADIGLELIRDK
ECCCCEECCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCC
KTATQVYTLNYEEYAVGNIVNQRTLGVNMDCK
CCCEEEEEECCHHHHHHHHHCCCEECCCCCCC
>Mature Secondary Structure
MIQITIIQIDNYGPWTVTPNPRRESDLQALQSRLYSDLNLQFGAHKGLVFYTRFDNLMAI
CEEEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCEEEE
TNGIDTETHKRIQDSIKNRYPFTVSMASGVAETPYEAQKIATAKIQNKGSAQDKYRTEIL
ECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHC
DIEELDNSIENTVTLAHVDINDITGTLTDLENAYDTYVSVNEVHLALIKELKKYNAMGFF
CHHHHCCHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHCCCCEEE
IGGDNFMAPCNGMTEEDFLEMFENIKNSTGIDLKAGIGIGKTAEDASNMADIGLELIRDK
ECCCCEECCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCC
KTATQVYTLNYEEYAVGNIVNQRTLGVNMDCK
CCCEEEEEECCHHHHHHHHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA