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The map label for this gene is sucD [H]

Identifier: 150401203

GI number: 150401203

Start: 796211

End: 797071

Strand: Direct

Name: sucD [H]

Synonym: Maeo_0774

Alternate gene names: 150401203

Gene position: 796211-797071 (Clockwise)

Preceding gene: 150401202

Following gene: 150401206

Centisome position: 50.73

GC content: 36.12

Gene sequence:

>861_bases
ATGATACTTTTAGACGAGAATACTAAGGCAGTAGTTCAGGGAATAACGGGGAAACAAGGTAGTTTCCACACAAAAAATAT
GGTAGAATGCGGAACAAATATTGTAGCAGGAGTTACCCCTGGAAAGGGAGGAATGGAATTATATGAAATACCAATATATG
ACACAGTGTTAGAAGCAGTTAAAAAACATGATGCCAATGCATCAATTATATTTGTTCCAGCCCCATTTGTAAAAGATGCG
GCCTATGAAGCAATTGATGCAGGAATTAAGCTAGTAATAATTATTACAGAACATGTGCCTGTTAATGATGCCATAGATAT
AATTAGTTATGCTAAATCAAATAATGTCCATGTGATTGGACCAAATACTCCGGGAATGGCATCTCCAAAAGTTGGAAAAT
TAGGGATTATTCCAATGAATGTTATAAAAGAAGGAAAAATAGGAATGGTTTCAAGAAGTGGAACACTCACATATGAAATA
GCAAATGAATTATCCAATAATGGATTTGGACAGTCCTCCTGTATTGGTATAGGGGGAGACCCAGTAATAGGATTAAGTTA
TATAGAAATATTGGAAATGTTTGAAAATGACCCCGACACAGATGCAGTAGTAATGATTGGTGAAATAGGGGGTAGCAATG
AAGAAATAGCTGCTGAATATGTAAAAACAATGAAAAAACCAGTAATTGCATATATTGCAGGTCAGACTGCACCAGAAGGT
AAAACCATGGGACATGCTGGAGCCATTATTGAAAAAGGAGTGGGAACAGCAGAAAGTAAAATGAAAACACTCGAACAGGC
AGGGGCCTTCGTAGTTAGAACAATTTCAGAAATACCAAAAGTATTAAAAGAAGTATTGTAG

Upstream 100 bases:

>100_bases
ATTTTTTCATAATAACTTATTTATATAATTGACATATATTTTGCATATATCTTTTTTCAAAACTAACGAATATTATATTT
ATTATTTATTTGGTGAGAAT

Downstream 100 bases:

>100_bases
TTAATCTTCAATAACTATCCCTTTATTGTTCCAAATAATTTTGGATAGGACATATTAGAATCTAGTTTATTCACATAATA
TTGAGTGAAAAGGTTCGAAG

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MILLDENTKAVVQGITGKQGSFHTKNMVECGTNIVAGVTPGKGGMELYEIPIYDTVLEAVKKHDANASIIFVPAPFVKDA
AYEAIDAGIKLVIIITEHVPVNDAIDIISYAKSNNVHVIGPNTPGMASPKVGKLGIIPMNVIKEGKIGMVSRSGTLTYEI
ANELSNNGFGQSSCIGIGGDPVIGLSYIEILEMFENDPDTDAVVMIGEIGGSNEEIAAEYVKTMKKPVIAYIAGQTAPEG
KTMGHAGAIIEKGVGTAESKMKTLEQAGAFVVRTISEIPKVLKEVL

Sequences:

>Translated_286_residues
MILLDENTKAVVQGITGKQGSFHTKNMVECGTNIVAGVTPGKGGMELYEIPIYDTVLEAVKKHDANASIIFVPAPFVKDA
AYEAIDAGIKLVIIITEHVPVNDAIDIISYAKSNNVHVIGPNTPGMASPKVGKLGIIPMNVIKEGKIGMVSRSGTLTYEI
ANELSNNGFGQSSCIGIGGDPVIGLSYIEILEMFENDPDTDAVVMIGEIGGSNEEIAAEYVKTMKKPVIAYIAGQTAPEG
KTMGHAGAIIEKGVGTAESKMKTLEQAGAFVVRTISEIPKVLKEVL
>Mature_286_residues
MILLDENTKAVVQGITGKQGSFHTKNMVECGTNIVAGVTPGKGGMELYEIPIYDTVLEAVKKHDANASIIFVPAPFVKDA
AYEAIDAGIKLVIIITEHVPVNDAIDIISYAKSNNVHVIGPNTPGMASPKVGKLGIIPMNVIKEGKIGMVSRSGTLTYEI
ANELSNNGFGQSSCIGIGGDPVIGLSYIEILEMFENDPDTDAVVMIGEIGGSNEEIAAEYVKTMKKPVIAYIAGQTAPEG
KTMGHAGAIIEKGVGTAESKMKTLEQAGAFVVRTISEIPKVLKEVL

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=283, Percent_Identity=46.643109540636, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI38569421, Length=311, Percent_Identity=27.3311897106109, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI38569423, Length=311, Percent_Identity=27.3311897106109, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1786949, Length=286, Percent_Identity=55.2447552447552, Blast_Score=311, Evalue=2e-86,
Organism=Escherichia coli, GI1786729, Length=197, Percent_Identity=25.8883248730964, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17550194, Length=281, Percent_Identity=46.9750889679715, Blast_Score=235, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17553126, Length=291, Percent_Identity=43.298969072165, Blast_Score=230, Evalue=6e-61,
Organism=Caenorhabditis elegans, GI17551266, Length=309, Percent_Identity=28.1553398058252, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17557344, Length=309, Percent_Identity=29.126213592233, Blast_Score=101, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6324716, Length=283, Percent_Identity=40.2826855123675, Blast_Score=200, Evalue=2e-52,
Organism=Drosophila melanogaster, GI21356559, Length=271, Percent_Identity=46.1254612546125, Blast_Score=243, Evalue=1e-64,
Organism=Drosophila melanogaster, GI28574296, Length=284, Percent_Identity=44.7183098591549, Blast_Score=221, Evalue=5e-58,
Organism=Drosophila melanogaster, GI281363475, Length=313, Percent_Identity=27.1565495207668, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI281363473, Length=313, Percent_Identity=27.1565495207668, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI281363477, Length=313, Percent_Identity=27.1565495207668, Blast_Score=97, Evalue=9e-21,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30156; Mature: 30156

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLDENTKAVVQGITGKQGSFHTKNMVECGTNIVAGVTPGKGGMELYEIPIYDTVLEAV
CEEECCCCCEEHCCCCCCCCCCCCCHHHHCCCCEEEECCCCCCCCEEEEECHHHHHHHHH
KKHDANASIIFVPAPFVKDAAYEAIDAGIKLVIIITEHVPVNDAIDIISYAKSNNVHVIG
HHCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEC
PNTPGMASPKVGKLGIIPMNVIKEGKIGMVSRSGTLTYEIANELSNNGFGQSSCIGIGGD
CCCCCCCCCCCCCEEEEEHHHHCCCCEEEEECCCEEEEEEHHHHCCCCCCCCCEEECCCC
PVIGLSYIEILEMFENDPDTDAVVMIGEIGGSNEEIAAEYVKTMKKPVIAYIAGQTAPEG
CEEHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCC
KTMGHAGAIIEKGVGTAESKMKTLEQAGAFVVRTISEIPKVLKEVL
CCCCCCCHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MILLDENTKAVVQGITGKQGSFHTKNMVECGTNIVAGVTPGKGGMELYEIPIYDTVLEAV
CEEECCCCCEEHCCCCCCCCCCCCCHHHHCCCCEEEECCCCCCCCEEEEECHHHHHHHHH
KKHDANASIIFVPAPFVKDAAYEAIDAGIKLVIIITEHVPVNDAIDIISYAKSNNVHVIG
HHCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEC
PNTPGMASPKVGKLGIIPMNVIKEGKIGMVSRSGTLTYEIANELSNNGFGQSSCIGIGGD
CCCCCCCCCCCCCEEEEEHHHHCCCCEEEEECCCEEEEEEHHHHCCCCCCCCCEEECCCC
PVIGLSYIEILEMFENDPDTDAVVMIGEIGGSNEEIAAEYVKTMKKPVIAYIAGQTAPEG
CEEHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCC
KTMGHAGAIIEKGVGTAESKMKTLEQAGAFVVRTISEIPKVLKEVL
CCCCCCCHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]