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The map label for this gene is purO

Identifier: 150401202

GI number: 150401202

Start: 795443

End: 796054

Strand: Direct

Name: purO

Synonym: Maeo_0773

Alternate gene names: 150401202

Gene position: 795443-796054 (Clockwise)

Preceding gene: 150401201

Following gene: 150401203

Centisome position: 50.68

GC content: 32.52

Gene sequence:

>612_bases
ATGTATATTGGAAGATTTTTAGTGGTTGGAAAAACACAGCAAGGAAAACCATTTGTATCTTATAGGGTATCAAGTAGGAG
TTTCCCAAACAGAAAAGCCGTAATAAATAATACCAACGACACAGTGGCAATTTTACCAAATGATTTAAATGATATGTTTG
CAAATCCATATATCGCATATAATTGTATAAAAATAGTAGGAAATACAGTAATAGCAACAAATGGAACACATACAGATATT
ATTGCAGATAAAATTAAATTGGAGCTCCCTATCAGAGATGCTTTGGCACTATCTTTAATTGCCATGGACTATGAAAAAGA
TGACTACAATACGCCAAGAATAGCCGTAGTTTTAAATGAAAATACAGCATATATGGGGTATGTAGCGGATAATGATATAA
GAATAAAAGAAGTCCCCCTTAAAGATGGATTGGCATATTATTTAAGCACCTATGAATGTTGTAGAATTAGCACGGAACAT
CAAAATATTGTAGTTGATGGAGAAAATCCAGAAGAAATTTGTAAATTTGTTATGGACTATGAAAAATTTGAAAAACCGGT
GTGCTGTGCAACGGCAACTATTGATGGAGATATCGAATTAGGAACTCTTTAA

Upstream 100 bases:

>100_bases
TTTTTTAGTAATATATTATAGGATTTGCCCTTAATTGGACATACTAACATGAAAACGACCGAAGATTGACTATAAATTGA
TAAATAAATGGTGATATATT

Downstream 100 bases:

>100_bases
TATTATTTTTTTATGTGTTATTTGGGAGCTCCCCAAATACCATATACCAATATTCTATTTTTTCATAATAACTTATTTAT
ATAATTGACATATATTTTGC

Product: IMP cyclohydrolase

Products: NA

Alternate protein names: IMP synthase; Inosinicase

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MYIGRFLVVGKTQQGKPFVSYRVSSRSFPNRKAVINNTNDTVAILPNDLNDMFANPYIAYNCIKIVGNTVIATNGTHTDI
IADKIKLELPIRDALALSLIAMDYEKDDYNTPRIAVVLNENTAYMGYVADNDIRIKEVPLKDGLAYYLSTYECCRISTEH
QNIVVDGENPEEICKFVMDYEKFEKPVCCATATIDGDIELGTL

Sequences:

>Translated_203_residues
MYIGRFLVVGKTQQGKPFVSYRVSSRSFPNRKAVINNTNDTVAILPNDLNDMFANPYIAYNCIKIVGNTVIATNGTHTDI
IADKIKLELPIRDALALSLIAMDYEKDDYNTPRIAVVLNENTAYMGYVADNDIRIKEVPLKDGLAYYLSTYECCRISTEH
QNIVVDGENPEEICKFVMDYEKFEKPVCCATATIDGDIELGTL
>Mature_203_residues
MYIGRFLVVGKTQQGKPFVSYRVSSRSFPNRKAVINNTNDTVAILPNDLNDMFANPYIAYNCIKIVGNTVIATNGTHTDI
IADKIKLELPIRDALALSLIAMDYEKDDYNTPRIAVVLNENTAYMGYVADNDIRIKEVPLKDGLAYYLSTYECCRISTEH
QNIVVDGENPEEICKFVMDYEKFEKPVCCATATIDGDIELGTL

Specific function: Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP

COG id: COG3363

COG function: function code F; Archaeal IMP cyclohydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal IMP cyclohydrolase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURO_META3 (A6UV34)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001324968.1
- ProteinModelPortal:   A6UV34
- SMR:   A6UV34
- STRING:   A6UV34
- GeneID:   5326256
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_0773
- eggNOG:   arNOG08037
- HOGENOM:   HBG539724
- OMA:   YIGRFLV
- ProtClustDB:   PRK04151
- BioCyc:   MAEO419665:MAEO_0773-MONOMER
- HAMAP:   MF_00705
- InterPro:   IPR010191
- InterPro:   IPR020600
- Gene3D:   G3DSA:3.60.20.20
- PIRSF:   PIRSF004866
- TIGRFAMs:   TIGR01922

Pfam domain/function: PF07826 IMP_cyclohyd; SSF75569 PurO_cyclohydro

EC number: =3.5.4.10

Molecular weight: Translated: 22766; Mature: 22766

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIGRFLVVGKTQQGKPFVSYRVSSRSFPNRKAVINNTNDTVAILPNDLNDMFANPYIAY
CEEEEEEEEECCCCCCCEEEEEECCCCCCCCCEEEECCCCEEEECCCCCHHHHCCCCCEE
NCIKIVGNTVIATNGTHTDIIADKIKLELPIRDALALSLIAMDYEKDDYNTPRIAVVLNE
EEEEECCCEEEEECCCCCEEEEEEEEEEECCHHHHEEEEEEEECCCCCCCCCEEEEEEEC
NTAYMGYVADNDIRIKEVPLKDGLAYYLSTYECCRISTEHQNIVVDGENPEEICKFVMDY
CCEEEEEEECCCEEEEECCCCCCCEEECCCEEEEEECCCCCEEEEECCCHHHHHHHHHHH
EKFEKPVCCATATIDGDIELGTL
HHHCCCEEEEEEEECCCEEECCC
>Mature Secondary Structure
MYIGRFLVVGKTQQGKPFVSYRVSSRSFPNRKAVINNTNDTVAILPNDLNDMFANPYIAY
CEEEEEEEEECCCCCCCEEEEEECCCCCCCCCEEEECCCCEEEECCCCCHHHHCCCCCEE
NCIKIVGNTVIATNGTHTDIIADKIKLELPIRDALALSLIAMDYEKDDYNTPRIAVVLNE
EEEEECCCEEEEECCCCCEEEEEEEEEEECCHHHHEEEEEEEECCCCCCCCCEEEEEEEC
NTAYMGYVADNDIRIKEVPLKDGLAYYLSTYECCRISTEHQNIVVDGENPEEICKFVMDY
CCEEEEEEECCCEEEEECCCCCCCEEECCCEEEEEECCCCCEEEEECCCHHHHHHHHHHH
EKFEKPVCCATATIDGDIELGTL
HHHCCCEEEEEEEECCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA