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The map label for this gene is pelA

Identifier: 150401149

GI number: 150401149

Start: 739484

End: 740530

Strand: Direct

Name: pelA

Synonym: Maeo_0720

Alternate gene names: 150401149

Gene position: 739484-740530 (Clockwise)

Preceding gene: 150401148

Following gene: 150401154

Centisome position: 47.12

GC content: 31.23

Gene sequence:

>1047_bases
ATGAAAATAATTAAAGAAATACCTGAAAAAAATATAATTAAAGTTATGCCCGAAAACTTAGATGATTTATGGCACCTATC
AAATATAATTTTAAAAAATAATGCTGTTTCTGCAATGACGGAGAGACGAACAGAAGATAAAGGGGATAAATTAAGGGCAG
ATAGAGGGACAAAAAGAAGAGTTTATTTAGGGGTTAAAGCAGAAAAAATAAAATTTGATGAAAATACCAATAGATTAAGG
GTCAGTGGCCCAATAATCCATGGTCCAGAGGATGTTCCAATTGGCTCATATCACACCATAGACATAGAACCACTTAAAGA
TGTATCCATACAAAAAAACTGGAAAAAATGGGATTTACAAAGGTTAAAAGATGCCGAAAATTCTGCAAAAAAACCAAAAA
TTATAGTTGTGATTATGGACGATAGCGATGCTACCGTATTTATAATCAGAGATTATGGGGTAAAAGAGATAGGACATATA
AAATCAAGATTATCTAAAAAATTAGACTACAAAAGGCAAGACCAAGAAAATATAAATTATTACAACGAAATACTTGAAGT
AATGTCGCCATACGAAGGAAAAATACTTGTAGCAGGTCCGGGATTTACAAAAAACAATTTTCAAAAATATCTGTCTGAAA
AACACAAAGATATGCTCCAAAGGGTTGTATTTGAATCCACAAACCATACTGGACGATTAGGACTTGCAGAAGTTTTAAAA
TCTGGTATCGTGGATAGAATTTATGGGGAAGCTCGCCTTAGTAAGGAAACTCAATTGGTAAATAAATTATTAGAAGAAAT
TTCAAAAAAAGGACTTGCAGTTTATGGTGTTGATGATGTTAAAAATGCTTTAAATTATTCTGCAATTGAAACTTTATTAA
TTACAGATGAATTTTTAAGAAAAAATAGGAGAATTTTAGAGGATTTAATTAATTCTGTTGAAGCTATTGGTGGGAGCTCC
ATTATAATCTCCACAGAATATGATGTAGGAAAACAGTTGAAAGCACTTGGTGGAATAGGAGGTTTATTAAGGTTTCCTAT
TGAATAA

Upstream 100 bases:

>100_bases
ATACATAAAAGTGTGCCAGAATGCCTATATAATCGAGTAGTTAAAAAATCATTTACTATAAATATACTTGAAAATGGAGA
ATTGTCATTTATGGGATAAT

Downstream 100 bases:

>100_bases
TTTTTTTATAATTATCTAATTATAAAATCATATATCATTCCAATTAAAGCACTTATTAAAACCACACTACCAAAATATTT
TAATGTTATTTTTAGCCCAT

Product: putative translation factor pelota

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MKIIKEIPEKNIIKVMPENLDDLWHLSNIILKNNAVSAMTERRTEDKGDKLRADRGTKRRVYLGVKAEKIKFDENTNRLR
VSGPIIHGPEDVPIGSYHTIDIEPLKDVSIQKNWKKWDLQRLKDAENSAKKPKIIVVIMDDSDATVFIIRDYGVKEIGHI
KSRLSKKLDYKRQDQENINYYNEILEVMSPYEGKILVAGPGFTKNNFQKYLSEKHKDMLQRVVFESTNHTGRLGLAEVLK
SGIVDRIYGEARLSKETQLVNKLLEEISKKGLAVYGVDDVKNALNYSAIETLLITDEFLRKNRRILEDLINSVEAIGGSS
IIISTEYDVGKQLKALGGIGGLLRFPIE

Sequences:

>Translated_348_residues
MKIIKEIPEKNIIKVMPENLDDLWHLSNIILKNNAVSAMTERRTEDKGDKLRADRGTKRRVYLGVKAEKIKFDENTNRLR
VSGPIIHGPEDVPIGSYHTIDIEPLKDVSIQKNWKKWDLQRLKDAENSAKKPKIIVVIMDDSDATVFIIRDYGVKEIGHI
KSRLSKKLDYKRQDQENINYYNEILEVMSPYEGKILVAGPGFTKNNFQKYLSEKHKDMLQRVVFESTNHTGRLGLAEVLK
SGIVDRIYGEARLSKETQLVNKLLEEISKKGLAVYGVDDVKNALNYSAIETLLITDEFLRKNRRILEDLINSVEAIGGSS
IIISTEYDVGKQLKALGGIGGLLRFPIE
>Mature_348_residues
MKIIKEIPEKNIIKVMPENLDDLWHLSNIILKNNAVSAMTERRTEDKGDKLRADRGTKRRVYLGVKAEKIKFDENTNRLR
VSGPIIHGPEDVPIGSYHTIDIEPLKDVSIQKNWKKWDLQRLKDAENSAKKPKIIVVIMDDSDATVFIIRDYGVKEIGHI
KSRLSKKLDYKRQDQENINYYNEILEVMSPYEGKILVAGPGFTKNNFQKYLSEKHKDMLQRVVFESTNHTGRLGLAEVLK
SGIVDRIYGEARLSKETQLVNKLLEEISKKGLAVYGVDDVKNALNYSAIETLLITDEFLRKNRRILEDLINSVEAIGGSS
IIISTEYDVGKQLKALGGIGGLLRFPIE

Specific function: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has end

COG id: COG1537

COG function: function code R; Predicted RNA-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eukaryotic release factor 1 family. Pelota subfamily

Homologues:

Organism=Homo sapiens, GI31880783, Length=376, Percent_Identity=25.7978723404255, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17554648, Length=360, Percent_Identity=28.0555555555556, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6324327, Length=363, Percent_Identity=25.068870523416, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17136914, Length=375, Percent_Identity=24.8, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PELO_META3 (A6UUY1)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001324915.1
- ProteinModelPortal:   A6UUY1
- SMR:   A6UUY1
- STRING:   A6UUY1
- GeneID:   5327637
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_0720
- eggNOG:   arNOG04486
- HOGENOM:   HBG646058
- OMA:   MKLVRKD
- ProtClustDB:   CLSK876101
- BioCyc:   MAEO419665:MAEO_0720-MONOMER
- GO:   GO:0005737
- GO:   GO:0006412
- HAMAP:   MF_01853
- InterPro:   IPR005140
- InterPro:   IPR005141
- InterPro:   IPR005142
- InterPro:   IPR004405
- PANTHER:   PTHR10853
- TIGRFAMs:   TIGR00111

Pfam domain/function: PF03463 eRF1_1; PF03464 eRF1_2; PF03465 eRF1_3

EC number: NA

Molecular weight: Translated: 39631; Mature: 39631

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIKEIPEKNIIKVMPENLDDLWHLSNIILKNNAVSAMTERRTEDKGDKLRADRGTKRR
CCCHHHCCCCCEEHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEECCCCCCEE
VYLGVKAEKIKFDENTNRLRVSGPIIHGPEDVPIGSYHTIDIEPLKDVSIQKNWKKWDLQ
EEEEEEEEEEEECCCCCEEEEECCEEECCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHH
RLKDAENSAKKPKIIVVIMDDSDATVFIIRDYGVKEIGHIKSRLSKKLDYKRQDQENINY
HHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHH
YNEILEVMSPYEGKILVAGPGFTKNNFQKYLSEKHKDMLQRVVFESTNHTGRLGLAEVLK
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
SGIVDRIYGEARLSKETQLVNKLLEEISKKGLAVYGVDDVKNALNYSAIETLLITDEFLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
KNRRILEDLINSVEAIGGSSIIISTEYDVGKQLKALGGIGGLLRFPIE
HHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCHHCCCCC
>Mature Secondary Structure
MKIIKEIPEKNIIKVMPENLDDLWHLSNIILKNNAVSAMTERRTEDKGDKLRADRGTKRR
CCCHHHCCCCCEEHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEECCCCCCEE
VYLGVKAEKIKFDENTNRLRVSGPIIHGPEDVPIGSYHTIDIEPLKDVSIQKNWKKWDLQ
EEEEEEEEEEEECCCCCEEEEECCEEECCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHH
RLKDAENSAKKPKIIVVIMDDSDATVFIIRDYGVKEIGHIKSRLSKKLDYKRQDQENINY
HHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHH
YNEILEVMSPYEGKILVAGPGFTKNNFQKYLSEKHKDMLQRVVFESTNHTGRLGLAEVLK
HHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
SGIVDRIYGEARLSKETQLVNKLLEEISKKGLAVYGVDDVKNALNYSAIETLLITDEFLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
KNRRILEDLINSVEAIGGSSIIISTEYDVGKQLKALGGIGGLLRFPIE
HHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA