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The map label for this gene is mre11 [H]

Identifier: 150401141

GI number: 150401141

Start: 730838

End: 732037

Strand: Reverse

Name: mre11 [H]

Synonym: Maeo_0712

Alternate gene names: 150401141

Gene position: 732037-730838 (Counterclockwise)

Preceding gene: 150401150

Following gene: 150401140

Centisome position: 46.64

GC content: 27.0

Gene sequence:

>1200_bases
ATGCAATTTGTACATATATCAGATAATCATTTAGGATACAGACAATATAATTTAGATGAAAGAGAAAAAGATATGTATAA
CGCATTTAATATGTGTATAGATGAAATAATTAATATAAAACCAGATTTTGTTGTGCATAGTGGGGATTTATTTGAGCAAT
CTACTCCGCCAATAAATGCACTATATACGGCAATAAAAGCTTTTGAGAAATTAAAAGAATGTAATATTCCAGTATATATA
ATTCATGGTAATCATGATGTTCCATCAAGAATAACCAAAGGAAGCCCTTATTTGATATTAAAAAATATGTTAAAAGATAA
ATTACGGACATTTACAGGGAAAAAATATCATATATTTAAAAAAAATAATAAAGAAATATTTATTGGTGGTTCGGATTATG
CCAGTATTGGAAAAACCACGGAGTTATTTGATGACTATAAATTAATAGAGCAAGAATCAAAGAATTATAAAAATAAAATA
TTAATTTTTCATCAAAGTATATATTCCTACTCAGATATACCATCGTATGAGCTCCAAGTCAATAATCTTCCAAGAGGGTT
TAATTACTATGCAGGAGGGCATATTCATAAAAGAATACTTAAAACAGTAGATTTGCAACATAAAGATAACAATACAAATA
ATAGCAACATTAATAACAGTAATAATAACAGTAATAACACCGATGGCAGTCAGGTTTTAGGGTGGAGTGGTTCCACAGAA
ATAACAGATTATGACGAATACAGAGACTACAAAAAAGAGGGAAAAGGCTTTTATTTAGTAGATATAAGTAAAAATGATTT
TGATATAAGTTGCGTGGATAAAATAAACATCAAATGCAGGGATTTTATAATTGACAAAGAAATAAAAAATGAAAATGATT
TTGAAAATTTGGTAAATGAATTAAATAATTATAATGACACAACAAAACCAATAGTTATTTGCGGAGTTGCCCGAGAATTG
CTGGGTAGTTTAAGGGAATTAATGAATAAAAAGGCACTGTATAGTAGATTATCAATAATTGAGGAGGATATTGATACAAC
AAGTATGTTTTTAGATATCAACAACAAAACTGATGAGATGTTTAGGGAATTCCTTAGAAATAAAAAATATGATGTAGAAT
TTGTGCAGGGATTATATTATGAAGCTTTAAAAGGGGATAACGAATTATATGACTATATTAATAATTATTATATAAAATAA

Upstream 100 bases:

>100_bases
AATATAATAATATAATAAATAATAAATACAAATATAAGATATTTAAAATATATAATTAATTTGATATACTTTTATTAAAT
ATAAGGGGGAGTGTGAAATT

Downstream 100 bases:

>100_bases
GGTGGGATTATGATTATAAAAAATATTAATATTAAAAATTTTAGGAGCCATAGTAATACCGACATATCATTTAAACAGGG
AATTACCACAATAATAGGAG

Product: metallophosphoesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MQFVHISDNHLGYRQYNLDEREKDMYNAFNMCIDEIINIKPDFVVHSGDLFEQSTPPINALYTAIKAFEKLKECNIPVYI
IHGNHDVPSRITKGSPYLILKNMLKDKLRTFTGKKYHIFKKNNKEIFIGGSDYASIGKTTELFDDYKLIEQESKNYKNKI
LIFHQSIYSYSDIPSYELQVNNLPRGFNYYAGGHIHKRILKTVDLQHKDNNTNNSNINNSNNNSNNTDGSQVLGWSGSTE
ITDYDEYRDYKKEGKGFYLVDISKNDFDISCVDKINIKCRDFIIDKEIKNENDFENLVNELNNYNDTTKPIVICGVAREL
LGSLRELMNKKALYSRLSIIEEDIDTTSMFLDINNKTDEMFREFLRNKKYDVEFVQGLYYEALKGDNELYDYINNYYIK

Sequences:

>Translated_399_residues
MQFVHISDNHLGYRQYNLDEREKDMYNAFNMCIDEIINIKPDFVVHSGDLFEQSTPPINALYTAIKAFEKLKECNIPVYI
IHGNHDVPSRITKGSPYLILKNMLKDKLRTFTGKKYHIFKKNNKEIFIGGSDYASIGKTTELFDDYKLIEQESKNYKNKI
LIFHQSIYSYSDIPSYELQVNNLPRGFNYYAGGHIHKRILKTVDLQHKDNNTNNSNINNSNNNSNNTDGSQVLGWSGSTE
ITDYDEYRDYKKEGKGFYLVDISKNDFDISCVDKINIKCRDFIIDKEIKNENDFENLVNELNNYNDTTKPIVICGVAREL
LGSLRELMNKKALYSRLSIIEEDIDTTSMFLDINNKTDEMFREFLRNKKYDVEFVQGLYYEALKGDNELYDYINNYYIK
>Mature_399_residues
MQFVHISDNHLGYRQYNLDEREKDMYNAFNMCIDEIINIKPDFVVHSGDLFEQSTPPINALYTAIKAFEKLKECNIPVYI
IHGNHDVPSRITKGSPYLILKNMLKDKLRTFTGKKYHIFKKNNKEIFIGGSDYASIGKTTELFDDYKLIEQESKNYKNKI
LIFHQSIYSYSDIPSYELQVNNLPRGFNYYAGGHIHKRILKTVDLQHKDNNTNNSNINNSNNNSNNTDGSQVLGWSGSTE
ITDYDEYRDYKKEGKGFYLVDISKNDFDISCVDKINIKCRDFIIDKEIKNENDFENLVNELNNYNDTTKPIVICGVAREL
LGSLRELMNKKALYSRLSIIEEDIDTTSMFLDINNKTDEMFREFLRNKKYDVEFVQGLYYEALKGDNELYDYINNYYIK

Specific function: Involved in DNA double-strand break repair (DSBR). The rad50/mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity [H]

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MRE11/RAD32 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 46719; Mature: 46719

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFVHISDNHLGYRQYNLDEREKDMYNAFNMCIDEIINIKPDFVVHSGDLFEQSTPPINA
CEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHH
LYTAIKAFEKLKECNIPVYIIHGNHDVPSRITKGSPYLILKNMLKDKLRTFTGKKYHIFK
HHHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEE
KNNKEIFIGGSDYASIGKTTELFDDYKLIEQESKNYKNKILIFHQSIYSYSDIPSYELQV
CCCCEEEECCCCCHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECHHCCCCCCCEEEEE
NNLPRGFNYYAGGHIHKRILKTVDLQHKDNNTNNSNINNSNNNSNNTDGSQVLGWSGSTE
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCC
ITDYDEYRDYKKEGKGFYLVDISKNDFDISCVDKINIKCRDFIIDKEIKNENDFENLVNE
CCCCHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCEEEEEEECHHHCCCCHHHHHHHH
LNNYNDTTKPIVICGVARELLGSLRELMNKKALYSRLSIIEEDIDTTSMFLDINNKTDEM
HHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHH
FREFLRNKKYDVEFVQGLYYEALKGDNELYDYINNYYIK
HHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHEECC
>Mature Secondary Structure
MQFVHISDNHLGYRQYNLDEREKDMYNAFNMCIDEIINIKPDFVVHSGDLFEQSTPPINA
CEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHH
LYTAIKAFEKLKECNIPVYIIHGNHDVPSRITKGSPYLILKNMLKDKLRTFTGKKYHIFK
HHHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEE
KNNKEIFIGGSDYASIGKTTELFDDYKLIEQESKNYKNKILIFHQSIYSYSDIPSYELQV
CCCCEEEECCCCCHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECHHCCCCCCCEEEEE
NNLPRGFNYYAGGHIHKRILKTVDLQHKDNNTNNSNINNSNNNSNNTDGSQVLGWSGSTE
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCC
ITDYDEYRDYKKEGKGFYLVDISKNDFDISCVDKINIKCRDFIIDKEIKNENDFENLVNE
CCCCHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCEEEEEEECHHHCCCCHHHHHHHH
LNNYNDTTKPIVICGVARELLGSLRELMNKKALYSRLSIIEEDIDTTSMFLDINNKTDEM
HHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHH
FREFLRNKKYDVEFVQGLYYEALKGDNELYDYINNYYIK
HHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA