Click here to switch to the map view.

The map label for this gene is ribD [C]

Identifier: 150401090

GI number: 150401090

Start: 679229

End: 679972

Strand: Reverse

Name: ribD [C]

Synonym: Maeo_0660

Alternate gene names: 150401090

Gene position: 679972-679229 (Counterclockwise)

Preceding gene: 150401091

Following gene: 150401089

Centisome position: 43.32

GC content: 30.11

Gene sequence:

>744_bases
ATGAATAATGAAATAAACACTGAAAATATAGAAATAGAAAATAATAATAAAAATAACAATACAGATAATATAAATGTAAA
ACCTTTCGTAATATCAAATGTGGGGATGTCCCTTGATGGAAAACTTGCCACAATAGAAAATGATTCAAGGATTTCAGGAG
AGGATGATTTAAAAAGGGTGCATAAAATAAGAAAGTCCGTAGATGGCATAATGGTTGGTATTGGCACAGTTTTAAAAGAT
GACCCGCGACTTACCGTTCATAAAATAAATGCAAAAAAAGAGGATAATCCAATTAGGATTGTGGTAGATAGTAATTTAAG
AATTCCATTAAATGCCCGTGTATTGAATGATGACGCAACAACCATAATAGCCACAACGGAAAATATGGGGGAAAATAAGA
ATATAAATGAAAAAATAAGGGAGTTAGCGAAAAAAAATATAATTATTATTAAAACAGGAATTGATAAAGTAGATTTGGTA
AAATTAATGGAATTGTTGTATAAAAAAGGAATAAAAAACATACTATTAGAAGGAGGGGGGACTCTAAATTGGGGCATGTT
TGAGAACAATCTTGTAGATGAAGTTAGGGTATATATTGCTCCAAAAATATTTGGGGGTAAGGGAGCTCCCACTTTTGTAG
ATGGAGATGGTTTTAAAACAGTTGATGAGTGCATCAAATTAGCGCTAAAAAATTGTTATAAATTAGATGATGGAATTGTT
ATTGAATATACTGTTAAAAAATAA

Upstream 100 bases:

>100_bases
AGATAAGGAAGAATATTTTAAGATATAGTCATGGAGATTTAAAAGATATTGAAGGATTGCATAGTTATCTAAAAAACAAG
GTAATAATGGTAGATAGAGA

Downstream 100 bases:

>100_bases
TAAATTTAAATATAAATTGCGGATAATAATTATTATACTACAATATAATAATATAATTTAATAATGCCCACAATATAATA
TTAAGGTATAATATTAAATA

Product: 5-amino-6-(5-phosphoribosylamino)uracil reductase

Products: NA

Alternate protein names: HTP reductase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MNNEINTENIEIENNNKNNNTDNINVKPFVISNVGMSLDGKLATIENDSRISGEDDLKRVHKIRKSVDGIMVGIGTVLKD
DPRLTVHKINAKKEDNPIRIVVDSNLRIPLNARVLNDDATTIIATTENMGENKNINEKIRELAKKNIIIIKTGIDKVDLV
KLMELLYKKGIKNILLEGGGTLNWGMFENNLVDEVRVYIAPKIFGGKGAPTFVDGDGFKTVDECIKLALKNCYKLDDGIV
IEYTVKK

Sequences:

>Translated_247_residues
MNNEINTENIEIENNNKNNNTDNINVKPFVISNVGMSLDGKLATIENDSRISGEDDLKRVHKIRKSVDGIMVGIGTVLKD
DPRLTVHKINAKKEDNPIRIVVDSNLRIPLNARVLNDDATTIIATTENMGENKNINEKIRELAKKNIIIIKTGIDKVDLV
KLMELLYKKGIKNILLEGGGTLNWGMFENNLVDEVRVYIAPKIFGGKGAPTFVDGDGFKTVDECIKLALKNCYKLDDGIV
IEYTVKK
>Mature_247_residues
MNNEINTENIEIENNNKNNNTDNINVKPFVISNVGMSLDGKLATIENDSRISGEDDLKRVHKIRKSVDGIMVGIGTVLKD
DPRLTVHKINAKKEDNPIRIVVDSNLRIPLNARVLNDDATTIIATTENMGENKNINEKIRELAKKNIIIIKTGIDKVDLV
KLMELLYKKGIKNILLEGGGTLNWGMFENNLVDEVRVYIAPKIFGGKGAPTFVDGDGFKTVDECIKLALKNCYKLDDGIV
IEYTVKK

Specific function: Converts 2,5-Diamino-6-(Ribosylamino)-4(3h)-Pyrimidinone 5'-Phosphate Into 5-Amino-6-(Ribosylamino)-2,4(1h,3h)- Pyrimidinedione 5'-Phosphate. [C]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=221, Percent_Identity=30.7692307692308, Blast_Score=90, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004794
- InterPro:   IPR006401
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF01872 RibD_C [H]

EC number: =1.1.1.193 [H]

Molecular weight: Translated: 27546; Mature: 27546

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNEINTENIEIENNNKNNNTDNINVKPFVISNVGMSLDGKLATIENDSRISGEDDLKRV
CCCCCCCCEEEEECCCCCCCCCCEEEEEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHH
HKIRKSVDGIMVGIGTVLKDDPRLTVHKINAKKEDNPIRIVVDSNLRIPLNARVLNDDAT
HHHHHHHCEEEEEEHHHCCCCCCEEEEEECCCCCCCCEEEEECCCEEEEEEEEEECCCCE
TIIATTENMGENKNINEKIRELAKKNIIIIKTGIDKVDLVKLMELLYKKGIKNILLEGGG
EEEEECCCCCCCCCHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHCCHHHEEECCCC
TLNWGMFENNLVDEVRVYIAPKIFGGKGAPTFVDGDGFKTVDECIKLALKNCYKLDDGIV
EEECCCCCCCCHHHEEEEEEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHEECCCCEE
IEYTVKK
EEEEECC
>Mature Secondary Structure
MNNEINTENIEIENNNKNNNTDNINVKPFVISNVGMSLDGKLATIENDSRISGEDDLKRV
CCCCCCCCEEEEECCCCCCCCCCEEEEEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHH
HKIRKSVDGIMVGIGTVLKDDPRLTVHKINAKKEDNPIRIVVDSNLRIPLNARVLNDDAT
HHHHHHHCEEEEEEHHHCCCCCCEEEEEECCCCCCCCEEEEECCCEEEEEEEEEECCCCE
TIIATTENMGENKNINEKIRELAKKNIIIIKTGIDKVDLVKLMELLYKKGIKNILLEGGG
EEEEECCCCCCCCCHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHCCHHHEEECCCC
TLNWGMFENNLVDEVRVYIAPKIFGGKGAPTFVDGDGFKTVDECIKLALKNCYKLDDGIV
EEECCCCCCCCHHHEEEEEEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHEECCCCEE
IEYTVKK
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]