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The map label for this gene is cofC

Identifier: 150401088

GI number: 150401088

Start: 677943

End: 678617

Strand: Direct

Name: cofC

Synonym: Maeo_0658

Alternate gene names: 150401088

Gene position: 677943-678617 (Clockwise)

Preceding gene: 150401087

Following gene: 150401093

Centisome position: 43.19

GC content: 28.89

Gene sequence:

>675_bases
ATGTTTTCTGCCTTAATACCTGTATCTCCACTAAATGCTGTAAAAACACGACTTAAAGATTTTTTAACGCCCGATGAACG
AATTGAATTAATAAAAAATATGTTATTAGATGTTTATGAAGGCATAAGCCCAATATGTGATAAAATATATGTTGTTAGTA
AGGATAAAGAAATATTGGAGTTTTTAAAACCCTACGCCGTAATACCAATTATGGAAACAGAAAATATAAAAGGACTAAAT
GATGCTTTAAATTATGCCTTTAATTATATTGAGGAGGACAATATTATAATAACTCCCGCAGACATTCCATTAATTAAAAA
AGAGAATATTAATAATATAGTAAAAGAATGTAAAGAAAATTCAGTAATATTGTGCCCTTCAAGAGGGGGAGGAACTAACT
TAATGGTATTAAATCGGAGCTCCATAAAAACCAGATATGAAGGATTTAGTTTTTTGAAACATATTGAGGAATGCAAAGAA
AATAATATAAATCCTATAATTTTTCCATCTTTTTATATTTCAATAGATATAAACACAGTGGAGGATTTGGGGGAAATTTT
AATTCATGGTGGGGGGACATATACATACAACTATCTAAAAAAGTTAAATATAAATGCAAAACCCAAACATTCATCTGCGG
GTAGATTTGAAGTAATTCGACAAAACACAGAATAA

Upstream 100 bases:

>100_bases
GCTTTCAATAATGCCAAATTATTTTTATAATATTTTTATAATAAATTTTTTATGACAACTAAAACTATAACTAAAAACCA
ATAAAATATCGTGATAATTT

Downstream 100 bases:

>100_bases
AAGCAATGTTCCATATAATAGTAATAGCAAAATCGAAGATTTTGCCTAATTCATATTTTTTTAAAAATTGTAGGTTAATC
GATATAAATTAAAAAATATA

Product: hypothetical protein

Products: NA

Alternate protein names: LP guanylyltransferase

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MFSALIPVSPLNAVKTRLKDFLTPDERIELIKNMLLDVYEGISPICDKIYVVSKDKEILEFLKPYAVIPIMETENIKGLN
DALNYAFNYIEEDNIIITPADIPLIKKENINNIVKECKENSVILCPSRGGGTNLMVLNRSSIKTRYEGFSFLKHIEECKE
NNINPIIFPSFYISIDINTVEDLGEILIHGGGTYTYNYLKKLNINAKPKHSSAGRFEVIRQNTE

Sequences:

>Translated_224_residues
MFSALIPVSPLNAVKTRLKDFLTPDERIELIKNMLLDVYEGISPICDKIYVVSKDKEILEFLKPYAVIPIMETENIKGLN
DALNYAFNYIEEDNIIITPADIPLIKKENINNIVKECKENSVILCPSRGGGTNLMVLNRSSIKTRYEGFSFLKHIEECKE
NNINPIIFPSFYISIDINTVEDLGEILIHGGGTYTYNYLKKLNINAKPKHSSAGRFEVIRQNTE
>Mature_224_residues
MFSALIPVSPLNAVKTRLKDFLTPDERIELIKNMLLDVYEGISPICDKIYVVSKDKEILEFLKPYAVIPIMETENIKGLN
DALNYAFNYIEEDNIIITPADIPLIKKENINNIVKECKENSVILCPSRGGGTNLMVLNRSSIKTRYEGFSFLKHIEECKE
NNINPIIFPSFYISIDINTVEDLGEILIHGGGTYTYNYLKKLNINAKPKHSSAGRFEVIRQNTE

Specific function: Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor

COG id: COG1920

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CofC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COFC_META3 (A6UUS0)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001324854.1
- ProteinModelPortal:   A6UUS0
- SMR:   A6UUS0
- STRING:   A6UUS0
- GeneID:   5326798
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_0658
- eggNOG:   arNOG08928
- HOGENOM:   HBG699055
- OMA:   SSAGRFN
- ProtClustDB:   CLSK876373
- BioCyc:   MAEO419665:MAEO_0658-MONOMER
- HAMAP:   MF_02114
- InterPro:   IPR002835
- TIGRFAMs:   TIGR03552

Pfam domain/function: PF01983 DUF121

EC number: =2.7.7.68

Molecular weight: Translated: 25476; Mature: 25476

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSALIPVSPLNAVKTRLKDFLTPDERIELIKNMLLDVYEGISPICDKIYVVSKDKEILE
CCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHEEEEEECCHHHHH
FLKPYAVIPIMETENIKGLNDALNYAFNYIEEDNIIITPADIPLIKKENINNIVKECKEN
HHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCEECCCCHHHHHHHHCCC
SVILCPSRGGGTNLMVLNRSSIKTRYEGFSFLKHIEECKENNINPIIFPSFYISIDINTV
CEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCH
EDLGEILIHGGGTYTYNYLKKLNINAKPKHSSAGRFEVIRQNTE
HHHHHEEEECCCEEEEEHHHEECCCCCCCCCCCCCEEEEECCCC
>Mature Secondary Structure
MFSALIPVSPLNAVKTRLKDFLTPDERIELIKNMLLDVYEGISPICDKIYVVSKDKEILE
CCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHEEEEEECCHHHHH
FLKPYAVIPIMETENIKGLNDALNYAFNYIEEDNIIITPADIPLIKKENINNIVKECKEN
HHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCEECCCCHHHHHHHHCCC
SVILCPSRGGGTNLMVLNRSSIKTRYEGFSFLKHIEECKENNINPIIFPSFYISIDINTV
CEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCH
EDLGEILIHGGGTYTYNYLKKLNINAKPKHSSAGRFEVIRQNTE
HHHHHEEEECCCEEEEEHHHEECCCCCCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA