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The map label for this gene is ttdA [C]

Identifier: 150401059

GI number: 150401059

Start: 648597

End: 649448

Strand: Reverse

Name: ttdA [C]

Synonym: Maeo_0629

Alternate gene names: 150401059

Gene position: 649448-648597 (Counterclockwise)

Preceding gene: 150401060

Following gene: 150401056

Centisome position: 41.38

GC content: 33.8

Gene sequence:

>852_bases
ATGGACAATAATATTGAAAATATTGTGGTAGAACTTTTTAAAGAAGCAGTTATCCATTTGCCTAATGATGTAAAAGAAGC
ATTGAAACGGGCAGAAAAAATTGAAGAAAATGAGCTTTCAAAAAATACTCTTGGTGCAATATTAAAAAATATAGAAATTG
CAGAGAAAGAAAATATTCCAATGTGTCAAGATACAGGAGTCCCAATATTATTTTTAAAAGTTGGTAAAAATATCAATTCT
ACTGAAATTATGGAAATTACTGATAAAATTAAAAAGGGAGTGGAAAAAGCCACAAAAGAAGTCCCACTTAGGCCTAATGT
GGTGCATCCATTGATAAGAGAAAATTTTAAAACAAATTGCGGTTTGGGAGCTCCCTTTATAAACATAGAATTTACAGAAC
AACTTGACAGAGAAATAGAAATAAGAGTATTTCCAAAGGGAGCAGGTAGTGAAAATATGAGCTCCCTAAAAATGTTAACT
CCATCGGAAGGAGTAAAGGGGATAAAAAAATTCGTATTGGAAACAATAGCAAGTGCAGGAGGAAAACCTTGCCCCCCAAT
ATTGGTTGGTGTTGGAATTGGTGGAACAGCAGATATATCTTTAAAATTGGCAAAAAAAGCATTATTGAGGAAAGTTGGGG
AAAGAAATAATGATAACGAAGTGGCAGAATTAGAGGCAGAATTATTGGAAAAAATAAACAAATTAGGTATTGGAACTATG
GGGCTGGGGGGAAATACCACGGCATTAGATGTATTTATTGAAATAAATGGCTGTCATACGGCTTCGCTTCCTGTTGGTAT
ATGTATTCAGTGTTGGGCTGGAAGAAGTGCTTCAAGAACTGTAAAATTATAA

Upstream 100 bases:

>100_bases
ATTTCCATTTTCATTAGAAAATTCAATAATCATAAGTTATTGTAATTTTATTTTTTATAATATTTATTTTATAGGCTTAT
TTATTATTTATGGTGATTTT

Downstream 100 bases:

>100_bases
ATATTAACAATAATACCAATAATATTCACGGTTTTAAATAATATAAATGACTATCACAACCACAGTCAGAACAACCAAAT
CCCTTTATAAATTCAAATTT

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MDNNIENIVVELFKEAVIHLPNDVKEALKRAEKIEENELSKNTLGAILKNIEIAEKENIPMCQDTGVPILFLKVGKNINS
TEIMEITDKIKKGVEKATKEVPLRPNVVHPLIRENFKTNCGLGAPFINIEFTEQLDREIEIRVFPKGAGSENMSSLKMLT
PSEGVKGIKKFVLETIASAGGKPCPPILVGVGIGGTADISLKLAKKALLRKVGERNNDNEVAELEAELLEKINKLGIGTM
GLGGNTTALDVFIEINGCHTASLPVGICIQCWAGRSASRTVKL

Sequences:

>Translated_283_residues
MDNNIENIVVELFKEAVIHLPNDVKEALKRAEKIEENELSKNTLGAILKNIEIAEKENIPMCQDTGVPILFLKVGKNINS
TEIMEITDKIKKGVEKATKEVPLRPNVVHPLIRENFKTNCGLGAPFINIEFTEQLDREIEIRVFPKGAGSENMSSLKMLT
PSEGVKGIKKFVLETIASAGGKPCPPILVGVGIGGTADISLKLAKKALLRKVGERNNDNEVAELEAELLEKINKLGIGTM
GLGGNTTALDVFIEINGCHTASLPVGICIQCWAGRSASRTVKL
>Mature_283_residues
MDNNIENIVVELFKEAVIHLPNDVKEALKRAEKIEENELSKNTLGAILKNIEIAEKENIPMCQDTGVPILFLKVGKNINS
TEIMEITDKIKKGVEKATKEVPLRPNVVHPLIRENFKTNCGLGAPFINIEFTEQLDREIEIRVFPKGAGSENMSSLKMLT
PSEGVKGIKKFVLETIASAGGKPCPPILVGVGIGGTADISLKLAKKALLRKVGERNNDNEVAELEAELLEKINKLGIGTM
GLGGNTTALDVFIEINGCHTASLPVGICIQCWAGRSASRTVKL

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=280, Percent_Identity=35, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1790564, Length=285, Percent_Identity=31.2280701754386, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787897, Length=256, Percent_Identity=31.25, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 30715; Mature: 30715

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNNIENIVVELFKEAVIHLPNDVKEALKRAEKIEENELSKNTLGAILKNIEIAEKENIP
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCC
MCQDTGVPILFLKVGKNINSTEIMEITDKIKKGVEKATKEVPLRPNVVHPLIRENFKTNC
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCC
GLGAPFINIEFTEQLDREIEIRVFPKGAGSENMSSLKMLTPSEGVKGIKKFVLETIASAG
CCCCCEEEEEEHHHCCCEEEEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCC
GKPCPPILVGVGIGGTADISLKLAKKALLRKVGERNNDNEVAELEAELLEKINKLGIGTM
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEE
GLGGNTTALDVFIEINGCHTASLPVGICIQCWAGRSASRTVKL
CCCCCCEEEEEEEEEECCEECCCCHHHHHHCCCCCCCCCEECC
>Mature Secondary Structure
MDNNIENIVVELFKEAVIHLPNDVKEALKRAEKIEENELSKNTLGAILKNIEIAEKENIP
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCC
MCQDTGVPILFLKVGKNINSTEIMEITDKIKKGVEKATKEVPLRPNVVHPLIRENFKTNC
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCC
GLGAPFINIEFTEQLDREIEIRVFPKGAGSENMSSLKMLTPSEGVKGIKKFVLETIASAG
CCCCCEEEEEEHHHCCCEEEEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCC
GKPCPPILVGVGIGGTADISLKLAKKALLRKVGERNNDNEVAELEAELLEKINKLGIGTM
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEE
GLGGNTTALDVFIEINGCHTASLPVGICIQCWAGRSASRTVKL
CCCCCCEEEEEEEEEECCEECCCCHHHHHHCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]