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The map label for this gene is htpX [H]

Identifier: 150401056

GI number: 150401056

Start: 645008

End: 645862

Strand: Reverse

Name: htpX [H]

Synonym: Maeo_0626

Alternate gene names: 150401056

Gene position: 645862-645008 (Counterclockwise)

Preceding gene: 150401059

Following gene: 150401055

Centisome position: 41.15

GC content: 34.27

Gene sequence:

>855_bases
ATGTTTTCAACTTTAAAAGTAGGAATATTAATGGCTGTTTTAACAGGCATATTATATAGTGCATTTACATTATTTAATGT
ATCGCCAATATTTGCTATAATATTTGCATTAATACCAAATTTGATAGCATATTTTTATAGCGATAAAATGGTATTGGCAA
GTTATGGGGCAAAAATTGTCGATGAAAGAGAAGCCCCTGCACTTCATAGGATTGTTGAAACTGTGGCAAATAGGGCGGGC
GTTCCTAAACCAAAAATTGCAATAGTGCATAGTGCTACCCCAAATGCTTTTGCAACAGGTAGAAATCCAAAAAACGGAGT
TGTTGCAGTAACTACGGGTATTATGGACATACTAACTCCGCAGGAATTAGAGGGGGTTATAGCCCATGAAATGAGTCATA
TAAAACATAGGGATATATTAATAAGTTCAATTGTTGCGGTATTAGCTGGTTCTATTATGTATTTGGCAAATGTAATGCAA
TGGGGAATGATTTTTGGATTTGGAGGTGATGATGAAGACAATCCATTAGGATTTATCGGTTCATTATTATTTATAATATT
TGCACCAATTGGGGCTACAATAGTTCAATTTGCAATATCAAGGCAAAGGGAATTTTATGCAGATGAAGGGGGAGCCAAAT
ATTCAAATCCTATATATTTAGCAAATGCACTTCAAAAATTGGAACGAGGAGTTAGCAGATATCCTATGGAACATGGAAAT
CCTGCAACAGAACATATGTTTATAGTAAATCCATTTAGGGGCAATAGTATAATGAAATTATTTTCAACACATCCGCCAAC
ACAGGAAAGAGTGGAAAAATTGATGGAAATGGCAAGAAATCCGAAATATAATTAA

Upstream 100 bases:

>100_bases
ACTACAACAATCTAGCAAAAAGATTAAAAATATATAAATATATATTAAATATATAGATAAAATAAATTTAAAAAACATTA
AACCAAATGGTGAATACAAA

Downstream 100 bases:

>100_bases
ATATATTAAATTAAAGGCAATATTATGGACAGTAAAGAATTAGGGCTAACTGTAAGAGCAGATAATAAAATAGGAGTATT
ACATAATTTAACAGGAATCA

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MFSTLKVGILMAVLTGILYSAFTLFNVSPIFAIIFALIPNLIAYFYSDKMVLASYGAKIVDEREAPALHRIVETVANRAG
VPKPKIAIVHSATPNAFATGRNPKNGVVAVTTGIMDILTPQELEGVIAHEMSHIKHRDILISSIVAVLAGSIMYLANVMQ
WGMIFGFGGDDEDNPLGFIGSLLFIIFAPIGATIVQFAISRQREFYADEGGAKYSNPIYLANALQKLERGVSRYPMEHGN
PATEHMFIVNPFRGNSIMKLFSTHPPTQERVEKLMEMARNPKYN

Sequences:

>Translated_284_residues
MFSTLKVGILMAVLTGILYSAFTLFNVSPIFAIIFALIPNLIAYFYSDKMVLASYGAKIVDEREAPALHRIVETVANRAG
VPKPKIAIVHSATPNAFATGRNPKNGVVAVTTGIMDILTPQELEGVIAHEMSHIKHRDILISSIVAVLAGSIMYLANVMQ
WGMIFGFGGDDEDNPLGFIGSLLFIIFAPIGATIVQFAISRQREFYADEGGAKYSNPIYLANALQKLERGVSRYPMEHGN
PATEHMFIVNPFRGNSIMKLFSTHPPTQERVEKLMEMARNPKYN
>Mature_284_residues
MFSTLKVGILMAVLTGILYSAFTLFNVSPIFAIIFALIPNLIAYFYSDKMVLASYGAKIVDEREAPALHRIVETVANRAG
VPKPKIAIVHSATPNAFATGRNPKNGVVAVTTGIMDILTPQELEGVIAHEMSHIKHRDILISSIVAVLAGSIMYLANVMQ
WGMIFGFGGDDEDNPLGFIGSLLFIIFAPIGATIVQFAISRQREFYADEGGAKYSNPIYLANALQKLERGVSRYPMEHGN
PATEHMFIVNPFRGNSIMKLFSTHPPTQERVEKLMEMARNPKYN

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=258, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 31263; Mature: 31263

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSTLKVGILMAVLTGILYSAFTLFNVSPIFAIIFALIPNLIAYFYSDKMVLASYGAKIV
CCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHH
DEREAPALHRIVETVANRAGVPKPKIAIVHSATPNAFATGRNPKNGVVAVTTGIMDILTP
CCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEHHHHHHCCH
QELEGVIAHEMSHIKHRDILISSIVAVLAGSIMYLANVMQWGMIFGFGGDDEDNPLGFIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHH
SLLFIIFAPIGATIVQFAISRQREFYADEGGAKYSNPIYLANALQKLERGVSRYPMEHGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
PATEHMFIVNPFRGNSIMKLFSTHPPTQERVEKLMEMARNPKYN
CCCCEEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MFSTLKVGILMAVLTGILYSAFTLFNVSPIFAIIFALIPNLIAYFYSDKMVLASYGAKIV
CCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHH
DEREAPALHRIVETVANRAGVPKPKIAIVHSATPNAFATGRNPKNGVVAVTTGIMDILTP
CCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEHHHHHHCCH
QELEGVIAHEMSHIKHRDILISSIVAVLAGSIMYLANVMQWGMIFGFGGDDEDNPLGFIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHH
SLLFIIFAPIGATIVQFAISRQREFYADEGGAKYSNPIYLANALQKLERGVSRYPMEHGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
PATEHMFIVNPFRGNSIMKLFSTHPPTQERVEKLMEMARNPKYN
CCCCEEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]