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The map label for this gene is pnk [H]

Identifier: 150400991

GI number: 150400991

Start: 575385

End: 577094

Strand: Direct

Name: pnk [H]

Synonym: Maeo_0560

Alternate gene names: 150400991

Gene position: 575385-577094 (Clockwise)

Preceding gene: 150400989

Following gene: 150400993

Centisome position: 36.66

GC content: 31.7

Gene sequence:

>1710_bases
ATGGATATGATAACTATTGCTATGAATATTGCTAAAAACATTGAAAAAGGAGTTAAACCCCTAATCGGCTGGGAGAAAGG
CACCGAAATAGTCAAAATCGGAGCAGATGGAACTCCAACAAAAAGAATTGACTTAATAGCCGAAGATATTGCCATAAATT
CCATCGAAAAACAATGTAGTGCTATTTTAATAAGCGAAGAAATAGGACATAAACAAATAGGAGATAATCCCAAATATGTT
ATTGTATTGGACCCAATTGATGGAACATATAATGCTTTAAACGATATACCAATATATTCCGTTTCTATTGCCATATGCAA
ATTAAATGATAGAAATATTGATGAATTAACCATAAATGATTTGGAAGTGGGAGTTGTAAGGAACATATCTACGGGAGAGG
TATATTTTGCCAAAAAAGGTAGCGGGGCTTTTGTATTTAAAAATAATATTCAAAAAAGAATATATACTTCAAAAATCACT
AATTTAAGCGATGCTTCGGTTGGAGTTTTTGCCTACGGCCTAACAACCAATACCTTAGATTTTATTAAAGATAGAAGAGT
AAAAAGAATAAGAATATTTGGTTCCGCAGCTTTGGAGCTATGTTTTGTTGCTCGTGGCTCATTAGATGCCTTTATAAATG
TAAATGAAACCACTCGTTTATGCGATATTGCGGGAGGTTTTGTAGTTCTTAAAGAGGCAGGAGGCATAATCTCCGACAGA
GACGGAAGAATTATAAATATGCCCCTTAATATTAATGCAAAAAATTCATTTATATGCTCCAATGATAAATTACATAAAAA
ATTTGTATCAATATTTGGAAATAAATGGAAATTAAAGCCCACAAAATTTGGAATAGTATCAAGAGCCGATAAAAAAGAGG
CTATTGAGTTGGTGTATGAAATTATAAATTATCTTGATTCAAAAAATATAGATTATGAATTAGAACAGGATATTTACAAT
AAAATATATAATACAAATAATAACAATATTGAAAATAAAGACAAATATTTAATGAAAGATGTTTCAGAAATATCACATAT
GATATCAATAGGAGGAGATGGGACCGTATTAAGGACATCGCGAATTGTAGAAGGTAATGAAATACCAATAATTACAGTAA
ATAAGGGGACCGTTGGATTTTTGGCGGAATTTGATGTGGAGGGTATATTTGATATTATAGAAGACATAATAAATGGAGAT
TATGAAATTGAAAAAAGAACCAAATGTTCGGGACATATAAAATATAAAGATAACAATCAAAAAACACTCCCCAGTGCCCT
TAATGAATTGGTAATAACTACAAAAAGCCCTGCAAAAATGATACAATTTGAAGTTTATGTAAATGGAAATTTTGTAGAAG
AGATAAGGGCAGATGGTCTTATAATATCCACCCCCACAGGTTCTACGGCATATTCTCTTAGTGCAGGGGGACCAATAGTA
GAGCCCCAAGTTGATGGCTTTGTGATAGTTCCAATATGTCCATTTAAATTATTTTCAAGACCCATTGTTGTAAATGGGAG
CTCCGAGATAAAAATAAAAATTATAAAAAAGGAAACGCTAGTTGCCGTAGATGGGACGATAGAAGGCGAATTAAAAAAAG
GAGACGAAATAATTTTAAGAAAATCCGATTCATACACATATTTTGTAAAAGGAAGAAACTTTTACGAAACACTTAGAAAA
TTAAGTGTAATTGATGGAGGAGCTAGATAA

Upstream 100 bases:

>100_bases
AAAGCTATGCTTTTGTATAAAATCCTAAAAGGATTTTATACTCAAAATTGGGACAAACAATGGACAGTTATTGAAGATTA
ACTATAATATTGGTGAAAAA

Downstream 100 bases:

>100_bases
TTAATTTTATAGGGCTCTTTATAATATATTTATAATAAAATATATTTATAATAACTATAAATATATAGATATTATTTTAA
CTCTTCAACATTTACAAGGG

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MDMITIAMNIAKNIEKGVKPLIGWEKGTEIVKIGADGTPTKRIDLIAEDIAINSIEKQCSAILISEEIGHKQIGDNPKYV
IVLDPIDGTYNALNDIPIYSVSIAICKLNDRNIDELTINDLEVGVVRNISTGEVYFAKKGSGAFVFKNNIQKRIYTSKIT
NLSDASVGVFAYGLTTNTLDFIKDRRVKRIRIFGSAALELCFVARGSLDAFINVNETTRLCDIAGGFVVLKEAGGIISDR
DGRIINMPLNINAKNSFICSNDKLHKKFVSIFGNKWKLKPTKFGIVSRADKKEAIELVYEIINYLDSKNIDYELEQDIYN
KIYNTNNNNIENKDKYLMKDVSEISHMISIGGDGTVLRTSRIVEGNEIPIITVNKGTVGFLAEFDVEGIFDIIEDIINGD
YEIEKRTKCSGHIKYKDNNQKTLPSALNELVITTKSPAKMIQFEVYVNGNFVEEIRADGLIISTPTGSTAYSLSAGGPIV
EPQVDGFVIVPICPFKLFSRPIVVNGSSEIKIKIIKKETLVAVDGTIEGELKKGDEIILRKSDSYTYFVKGRNFYETLRK
LSVIDGGAR

Sequences:

>Translated_569_residues
MDMITIAMNIAKNIEKGVKPLIGWEKGTEIVKIGADGTPTKRIDLIAEDIAINSIEKQCSAILISEEIGHKQIGDNPKYV
IVLDPIDGTYNALNDIPIYSVSIAICKLNDRNIDELTINDLEVGVVRNISTGEVYFAKKGSGAFVFKNNIQKRIYTSKIT
NLSDASVGVFAYGLTTNTLDFIKDRRVKRIRIFGSAALELCFVARGSLDAFINVNETTRLCDIAGGFVVLKEAGGIISDR
DGRIINMPLNINAKNSFICSNDKLHKKFVSIFGNKWKLKPTKFGIVSRADKKEAIELVYEIINYLDSKNIDYELEQDIYN
KIYNTNNNNIENKDKYLMKDVSEISHMISIGGDGTVLRTSRIVEGNEIPIITVNKGTVGFLAEFDVEGIFDIIEDIINGD
YEIEKRTKCSGHIKYKDNNQKTLPSALNELVITTKSPAKMIQFEVYVNGNFVEEIRADGLIISTPTGSTAYSLSAGGPIV
EPQVDGFVIVPICPFKLFSRPIVVNGSSEIKIKIIKKETLVAVDGTIEGELKKGDEIILRKSDSYTYFVKGRNFYETLRK
LSVIDGGAR
>Mature_569_residues
MDMITIAMNIAKNIEKGVKPLIGWEKGTEIVKIGADGTPTKRIDLIAEDIAINSIEKQCSAILISEEIGHKQIGDNPKYV
IVLDPIDGTYNALNDIPIYSVSIAICKLNDRNIDELTINDLEVGVVRNISTGEVYFAKKGSGAFVFKNNIQKRIYTSKIT
NLSDASVGVFAYGLTTNTLDFIKDRRVKRIRIFGSAALELCFVARGSLDAFINVNETTRLCDIAGGFVVLKEAGGIISDR
DGRIINMPLNINAKNSFICSNDKLHKKFVSIFGNKWKLKPTKFGIVSRADKKEAIELVYEIINYLDSKNIDYELEQDIYN
KIYNTNNNNIENKDKYLMKDVSEISHMISIGGDGTVLRTSRIVEGNEIPIITVNKGTVGFLAEFDVEGIFDIIEDIINGD
YEIEKRTKCSGHIKYKDNNQKTLPSALNELVITTKSPAKMIQFEVYVNGNFVEEIRADGLIISTPTGSTAYSLSAGGPIV
EPQVDGFVIVPICPFKLFSRPIVVNGSSEIKIKIIKKETLVAVDGTIEGELKKGDEIILRKSDSYTYFVKGRNFYETLRK
LSVIDGGAR

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=302, Percent_Identity=26.158940397351, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI221625487, Length=208, Percent_Identity=32.2115384615385, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI5031789, Length=208, Percent_Identity=32.2115384615385, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI7657236, Length=223, Percent_Identity=29.5964125560538, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1788968, Length=274, Percent_Identity=31.3868613138686, Blast_Score=160, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI193202572, Length=199, Percent_Identity=27.1356783919598, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6325068, Length=248, Percent_Identity=30.6451612903226, Blast_Score=136, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6320794, Length=278, Percent_Identity=30.5755395683453, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6322509, Length=232, Percent_Identity=33.1896551724138, Blast_Score=117, Evalue=5e-27,
Organism=Drosophila melanogaster, GI28573826, Length=290, Percent_Identity=27.5862068965517, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573830, Length=290, Percent_Identity=27.5862068965517, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573828, Length=290, Percent_Identity=27.5862068965517, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI161077047, Length=290, Percent_Identity=27.5862068965517, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28573832, Length=290, Percent_Identity=27.5862068965517, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24653422, Length=240, Percent_Identity=27.5, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24664922, Length=182, Percent_Identity=36.2637362637363, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI20129957, Length=240, Percent_Identity=27.5, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24653424, Length=239, Percent_Identity=27.6150627615063, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281363323, Length=239, Percent_Identity=27.6150627615063, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281363321, Length=239, Percent_Identity=27.6150627615063, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24664926, Length=212, Percent_Identity=30.188679245283, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24664918, Length=215, Percent_Identity=33.953488372093, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21357303, Length=207, Percent_Identity=29.951690821256, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21357957, Length=208, Percent_Identity=32.2115384615385, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR021175
- InterPro:   IPR000760
- InterPro:   IPR002504 [H]

Pfam domain/function: PF00459 Inositol_P; PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 63121; Mature: 63121

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS00629 IMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMITIAMNIAKNIEKGVKPLIGWEKGTEIVKIGADGTPTKRIDLIAEDIAINSIEKQCS
CCEEEEEHHHHHHHHHCCHHHCCCCCCCEEEEECCCCCCCCEEEEEHHHHHHHHHHHHHH
AILISEEIGHKQIGDNPKYVIVLDPIDGTYNALNDIPIYSVSIAICKLNDRNIDELTIND
EEEEEHHCCCHHCCCCCCEEEEECCCCCCCHHHCCCCEEEEEEEEEEECCCCCCEEEECC
LEVGVVRNISTGEVYFAKKGSGAFVFKNNIQKRIYTSKITNLSDASVGVFAYGLTTNTLD
EEEEEEEECCCCEEEEEECCCEEEEECCCCHHHEEHHHCCCCCCCCEEEEEEECCCCHHH
FIKDRRVKRIRIFGSAALELCFVARGSLDAFINVNETTRLCDIAGGFVVLKEAGGIISDR
HHHCCCEEEEEEECHHHHEEEEEECCCCEEEEECCCCCEEEEECCCEEEEEECCCEEECC
DGRIINMPLNINAKNSFICSNDKLHKKFVSIFGNKWKLKPTKFGIVSRADKKEAIELVYE
CCEEEEEEEEECCCCCEEECCCHHHHHHHHHCCCCEEECCCEECEEECCCHHHHHHHHHH
IINYLDSKNIDYELEQDIYNKIYNTNNNNIENKDKYLMKDVSEISHMISIGGDGTVLRTS
HHHHHCCCCCCEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCEEEEEE
RIVEGNEIPIITVNKGTVGFLAEFDVEGIFDIIEDIINGDYEIEKRTKCSGHIKYKDNNQ
EEECCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCC
KTLPSALNELVITTKSPAKMIQFEVYVNGNFVEEIRADGLIISTPTGSTAYSLSAGGPIV
CHHHHHHHHEEEECCCCCEEEEEEEEECCCCHHHHCCCCEEEECCCCCCEEEECCCCCEE
EPQVDGFVIVPICPFKLFSRPIVVNGSSEIKIKIIKKETLVAVDGTIEGELKKGDEIILR
CCCCCCEEEEEECCHHHHCCCEEEECCCEEEEEEEEEEEEEEECCEEECCCCCCCEEEEE
KSDSYTYFVKGRNFYETLRKLSVIDGGAR
ECCCEEEEEECCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDMITIAMNIAKNIEKGVKPLIGWEKGTEIVKIGADGTPTKRIDLIAEDIAINSIEKQCS
CCEEEEEHHHHHHHHHCCHHHCCCCCCCEEEEECCCCCCCCEEEEEHHHHHHHHHHHHHH
AILISEEIGHKQIGDNPKYVIVLDPIDGTYNALNDIPIYSVSIAICKLNDRNIDELTIND
EEEEEHHCCCHHCCCCCCEEEEECCCCCCCHHHCCCCEEEEEEEEEEECCCCCCEEEECC
LEVGVVRNISTGEVYFAKKGSGAFVFKNNIQKRIYTSKITNLSDASVGVFAYGLTTNTLD
EEEEEEEECCCCEEEEEECCCEEEEECCCCHHHEEHHHCCCCCCCCEEEEEEECCCCHHH
FIKDRRVKRIRIFGSAALELCFVARGSLDAFINVNETTRLCDIAGGFVVLKEAGGIISDR
HHHCCCEEEEEEECHHHHEEEEEECCCCEEEEECCCCCEEEEECCCEEEEEECCCEEECC
DGRIINMPLNINAKNSFICSNDKLHKKFVSIFGNKWKLKPTKFGIVSRADKKEAIELVYE
CCEEEEEEEEECCCCCEEECCCHHHHHHHHHCCCCEEECCCEECEEECCCHHHHHHHHHH
IINYLDSKNIDYELEQDIYNKIYNTNNNNIENKDKYLMKDVSEISHMISIGGDGTVLRTS
HHHHHCCCCCCEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCEEEEEE
RIVEGNEIPIITVNKGTVGFLAEFDVEGIFDIIEDIINGDYEIEKRTKCSGHIKYKDNNQ
EEECCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCC
KTLPSALNELVITTKSPAKMIQFEVYVNGNFVEEIRADGLIISTPTGSTAYSLSAGGPIV
CHHHHHHHHEEEECCCCCEEEEEEEEECCCCHHHHCCCCEEEECCCCCCEEEECCCCCEE
EPQVDGFVIVPICPFKLFSRPIVVNGSSEIKIKIIKKETLVAVDGTIEGELKKGDEIILR
CCCCCCEEEEEECCHHHHCCCEEEECCCEEEEEEEEEEEEEEECCEEECCCCCCCEEEEE
KSDSYTYFVKGRNFYETLRKLSVIDGGAR
ECCCEEEEEECCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA