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The map label for this gene is pgk [H]

Identifier: 150400927

GI number: 150400927

Start: 518435

End: 519694

Strand: Direct

Name: pgk [H]

Synonym: Maeo_0495

Alternate gene names: 150400927

Gene position: 518435-519694 (Clockwise)

Preceding gene: 150400922

Following gene: 150400928

Centisome position: 33.03

GC content: 33.81

Gene sequence:

>1260_bases
ATGCTATTGACCATTGATAATTTTGATTTTAAAGGAAAAACTGTTGCATTGAGAGTAGATATAAACAGCCCCATAGACCC
CCAAAATGAGATAATATTAGATGATGCACGAATAAGGGCATGTTCTGATACAATAACAGAATTATCCAATAATGGAGCAA
AAGTAGTAATAATGGCACACCAAAGCCGACCGGGAAAAAAAGATTATACTACCTTGAAATCCCATGCCGAAATACTTTCC
AAAGTATTAAATAAAGAAGTTAAATATGTAGATGACATGTTTGGCTCTCATGCCGAGTCTACAATAATTAATATGGAAGA
TGGCGACATCGTATTGCTTGAAAATGTTAGATTCTATGCCGAAGAAGTTTTAAAAGATTGGAAAAAATGGAAAGACGACA
CACCTAAAAAACAGGGCAAAACCCTAATGATACGAAAGATACACCATTTATTTGATTATTTTATAAATGATGCTTTTGCA
GCGGCTCATAGGGCTCAACCATCTTTGGTGGGATTAGCATATTATGTTCCAGCAATTGCGGGAAATGTTATGTATAATGA
AATAAAAACCCTTAGTAAGGTATTAAATAATCCCGAAAAGCCTTGTGTTTTTGTGTTAGGTGGTGCAAAAGCTGATGATA
GTATCGAAGTAATTAAAAATGTTCTCAGTGGAAACATTGCAGATAAAATATTAATATCAGGAATTGTAGCGAATATATTT
TTGCTGGCAAAAGGCTACGACATAGGAGATAATAAGGCCGTAGTAGAAAGTATGGGATATTTAAATCAAATAGAAATTGC
AGAACAGTTAATAGCTACATACGGCGATAAAATTGTATTTCCAATAGATGTTGCACTAAATATCGATGGAGAACGAAAAG
AAGTAGATTTAAATCTTAATGAAAAAATAGAATATCCTATTTATGATATGGGTAGTAAAACTATAGAATTATATAATGGC
CACATAAAAAATGCTAAAACTGTGGTTGCCAATGGTCCTGCTGGTGTTTTCGAAAATAAAAACTTCATAAAAGGGACAGA
AGGTATTTTAAATAGTATGGCTGAAACCGATGCATTTACTATAATTGGCGGAGGACATTTATCTGCTGCGGCGGCGGTTG
TTGGATTGGATAAAAAAATGGACCACATAAGCACCGGGGGAGGTGCATGCATTGAGTTTTTAGCAGGAAAAACCCTTCCA
GTAATCAAAGTTTTGGAAAATTCATATAATAAATATAGGCAATATGGTAGAAATATATAA

Upstream 100 bases:

>100_bases
AGATAATAAAGATAAAAATAAACGAAATATATGCGCCGTATTATGATATACGAATATCAATATTATATGTAAATCTTATA
TAATTTCAAGGAGGAATATT

Downstream 100 bases:

>100_bases
CTAAAATATGAATAAATTACTATTTTATCATATATATAATATGATAAATATATAACTTAATATTAATATAATTGTTTTAT
CAATTTTATCAATTTTTTAG

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MLLTIDNFDFKGKTVALRVDINSPIDPQNEIILDDARIRACSDTITELSNNGAKVVIMAHQSRPGKKDYTTLKSHAEILS
KVLNKEVKYVDDMFGSHAESTIINMEDGDIVLLENVRFYAEEVLKDWKKWKDDTPKKQGKTLMIRKIHHLFDYFINDAFA
AAHRAQPSLVGLAYYVPAIAGNVMYNEIKTLSKVLNNPEKPCVFVLGGAKADDSIEVIKNVLSGNIADKILISGIVANIF
LLAKGYDIGDNKAVVESMGYLNQIEIAEQLIATYGDKIVFPIDVALNIDGERKEVDLNLNEKIEYPIYDMGSKTIELYNG
HIKNAKTVVANGPAGVFENKNFIKGTEGILNSMAETDAFTIIGGGHLSAAAAVVGLDKKMDHISTGGGACIEFLAGKTLP
VIKVLENSYNKYRQYGRNI

Sequences:

>Translated_419_residues
MLLTIDNFDFKGKTVALRVDINSPIDPQNEIILDDARIRACSDTITELSNNGAKVVIMAHQSRPGKKDYTTLKSHAEILS
KVLNKEVKYVDDMFGSHAESTIINMEDGDIVLLENVRFYAEEVLKDWKKWKDDTPKKQGKTLMIRKIHHLFDYFINDAFA
AAHRAQPSLVGLAYYVPAIAGNVMYNEIKTLSKVLNNPEKPCVFVLGGAKADDSIEVIKNVLSGNIADKILISGIVANIF
LLAKGYDIGDNKAVVESMGYLNQIEIAEQLIATYGDKIVFPIDVALNIDGERKEVDLNLNEKIEYPIYDMGSKTIELYNG
HIKNAKTVVANGPAGVFENKNFIKGTEGILNSMAETDAFTIIGGGHLSAAAAVVGLDKKMDHISTGGGACIEFLAGKTLP
VIKVLENSYNKYRQYGRNI
>Mature_419_residues
MLLTIDNFDFKGKTVALRVDINSPIDPQNEIILDDARIRACSDTITELSNNGAKVVIMAHQSRPGKKDYTTLKSHAEILS
KVLNKEVKYVDDMFGSHAESTIINMEDGDIVLLENVRFYAEEVLKDWKKWKDDTPKKQGKTLMIRKIHHLFDYFINDAFA
AAHRAQPSLVGLAYYVPAIAGNVMYNEIKTLSKVLNNPEKPCVFVLGGAKADDSIEVIKNVLSGNIADKILISGIVANIF
LLAKGYDIGDNKAVVESMGYLNQIEIAEQLIATYGDKIVFPIDVALNIDGERKEVDLNLNEKIEYPIYDMGSKTIELYNG
HIKNAKTVVANGPAGVFENKNFIKGTEGILNSMAETDAFTIIGGGHLSAAAAVVGLDKKMDHISTGGGACIEFLAGKTLP
VIKVLENSYNKYRQYGRNI

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505763, Length=421, Percent_Identity=33.729216152019, Blast_Score=195, Evalue=5e-50,
Organism=Homo sapiens, GI31543397, Length=423, Percent_Identity=32.1513002364066, Blast_Score=186, Evalue=3e-47,
Organism=Escherichia coli, GI1789294, Length=415, Percent_Identity=33.4939759036145, Blast_Score=209, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI17508823, Length=418, Percent_Identity=35.4066985645933, Blast_Score=215, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6319857, Length=421, Percent_Identity=33.2541567695962, Blast_Score=186, Evalue=8e-48,
Organism=Drosophila melanogaster, GI24581203, Length=426, Percent_Identity=35.6807511737089, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI17136394, Length=435, Percent_Identity=33.5632183908046, Blast_Score=191, Evalue=1e-48,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 46162; Mature: 46162

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTIDNFDFKGKTVALRVDINSPIDPQNEIILDDARIRACSDTITELSNNGAKVVIMAH
CEEEEECCCCCCCEEEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCEEEEEEE
QSRPGKKDYTTLKSHAEILSKVLNKEVKYVDDMFGSHAESTIINMEDGDIVLLENVRFYA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCHHHHH
EEVLKDWKKWKDDTPKKQGKTLMIRKIHHLFDYFINDAFAAAHRAQPSLVGLAYYVPAIA
HHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
GNVMYNEIKTLSKVLNNPEKPCVFVLGGAKADDSIEVIKNVLSGNIADKILISGIVANIF
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
LLAKGYDIGDNKAVVESMGYLNQIEIAEQLIATYGDKIVFPIDVALNIDGERKEVDLNLN
HHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCEEEECCCC
EKIEYPIYDMGSKTIELYNGHIKNAKTVVANGPAGVFENKNFIKGTEGILNSMAETDAFT
CCCCCCEECCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCEE
IIGGGHLSAAAAVVGLDKKMDHISTGGGACIEFLAGKTLPVIKVLENSYNKYRQYGRNI
EEECCHHHHHHHHHHCHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLLTIDNFDFKGKTVALRVDINSPIDPQNEIILDDARIRACSDTITELSNNGAKVVIMAH
CEEEEECCCCCCCEEEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCEEEEEEE
QSRPGKKDYTTLKSHAEILSKVLNKEVKYVDDMFGSHAESTIINMEDGDIVLLENVRFYA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCHHHHH
EEVLKDWKKWKDDTPKKQGKTLMIRKIHHLFDYFINDAFAAAHRAQPSLVGLAYYVPAIA
HHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
GNVMYNEIKTLSKVLNNPEKPCVFVLGGAKADDSIEVIKNVLSGNIADKILISGIVANIF
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
LLAKGYDIGDNKAVVESMGYLNQIEIAEQLIATYGDKIVFPIDVALNIDGERKEVDLNLN
HHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCEEEECCCC
EKIEYPIYDMGSKTIELYNGHIKNAKTVVANGPAGVFENKNFIKGTEGILNSMAETDAFT
CCCCCCEECCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCEE
IIGGGHLSAAAAVVGLDKKMDHISTGGGACIEFLAGKTLPVIKVLENSYNKYRQYGRNI
EEECCHHHHHHHHHHCHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA