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The map label for this gene is cobY [H]

Identifier: 150400640

GI number: 150400640

Start: 216346

End: 216954

Strand: Direct

Name: cobY [H]

Synonym: Maeo_0202

Alternate gene names: 150400640

Gene position: 216346-216954 (Clockwise)

Preceding gene: 150400636

Following gene: 150400641

Centisome position: 13.78

GC content: 25.12

Gene sequence:

>609_bases
ATGGATGCATTAATAATGGCTGGGGGGAAAGGCACACGATTAAATTTAAATGTTGAAAAACCACTTTTAAAAATATTGGA
TAAGCCTATGATAGATTATATTATTGGGGAGCTCCTAAAATCAAAAATAAATAAAATATATATAGCCACATCTAAACACA
CCCCGAAAACTAAAAAATATTTAATTAATAAATATAACAATAATAATAAAGTAATTATTGTAGATACGGAAGGCACTGAC
TATATCCACGATTTAAATCAGTGCATTTCTTATTTTTCTAAACCATTTATGATGCTTTCCTGCGATATTCCGTCTATAAA
ATCGAAACTAATAAATAATATAATAAATTATTATAATAATATAAACAATAAAAAAGAAGCTTTATGCGTAGTTATTGAAA
AAAATAACTATTTAGGCAATCCTACTTTAATTTTAAATGAATATGATAAGATTCCCGCTGGCATAAATATATTAAGCCCT
AAACAGGGTTGTCAAACTGAGGAAATATATGTGGTAAATGAACCACTAATAAATATAAATACTTTGAAAGATAAAGAAAT
TGTTGAAAACATATTTGGTGGAGAATATAAAAAATTAAATAAAAAATAA

Upstream 100 bases:

>100_bases
AATTTTTCTCTGAAAAATTTATACGATCGTAAAAATCGCTTTGCGATTTTGAGACGGTTTAGTGAAAAAGACCGAAGGTT
GACTATAAAGGAGGAAAAAT

Downstream 100 bases:

>100_bases
CACATATTGGTGATTTATTGTGATAGCCCCTACTAAACCAGAAGCTAAGGTATCTTTTAAAAAATTATATGGAAAATCCG
TTGTAGGAGATATGGGTAGT

Product: hypothetical protein

Products: NA

Alternate protein names: AdoCbi-P guanylyltransferase [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MDALIMAGGKGTRLNLNVEKPLLKILDKPMIDYIIGELLKSKINKIYIATSKHTPKTKKYLINKYNNNNKVIIVDTEGTD
YIHDLNQCISYFSKPFMMLSCDIPSIKSKLINNIINYYNNINNKKEALCVVIEKNNYLGNPTLILNEYDKIPAGINILSP
KQGCQTEEIYVVNEPLININTLKDKEIVENIFGGEYKKLNKK

Sequences:

>Translated_202_residues
MDALIMAGGKGTRLNLNVEKPLLKILDKPMIDYIIGELLKSKINKIYIATSKHTPKTKKYLINKYNNNNKVIIVDTEGTD
YIHDLNQCISYFSKPFMMLSCDIPSIKSKLINNIINYYNNINNKKEALCVVIEKNNYLGNPTLILNEYDKIPAGINILSP
KQGCQTEEIYVVNEPLININTLKDKEIVENIFGGEYKKLNKK
>Mature_202_residues
MDALIMAGGKGTRLNLNVEKPLLKILDKPMIDYIIGELLKSKINKIYIATSKHTPKTKKYLINKYNNNNKVIIVDTEGTD
YIHDLNQCISYFSKPFMMLSCDIPSIKSKLINNIINYYNNINNKKEALCVVIEKNNYLGNPTLILNEYDKIPAGINILSP
KQGCQTEEIYVVNEPLININTLKDKEIVENIFGGEYKKLNKK

Specific function: Guanylyltransferase that catalyzes the synthesis of adenosylcobinamide-GDP (AdoCbi-GDP) from adenosylcobinamide- phosphate (AdoCbi-P) and GTP. Is involved in adenosylcobalamin biosynthesis. Binds one GTP per dimer. Can not use other NTPs or GDP. Does not

COG id: COG2266

COG function: function code H; GTP:adenosylcobinamide-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005245
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.62 [H]

Molecular weight: Translated: 23058; Mature: 23058

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDALIMAGGKGTRLNLNVEKPLLKILDKPMIDYIIGELLKSKINKIYIATSKHTPKTKKY
CCEEEEECCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHCEEEEEECCCCCHHHHH
LINKYNNNNKVIIVDTEGTDYIHDLNQCISYFSKPFMMLSCDIPSIKSKLINNIINYYNN
HHHEECCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHC
INNKKEALCVVIEKNNYLGNPTLILNEYDKIPAGINILSPKQGCQTEEIYVVNEPLININ
CCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCEEECCCCCCCCCEEEEECCCEEEEE
TLKDKEIVENIFGGEYKKLNKK
CCCHHHHHHHHHCCCHHHCCCC
>Mature Secondary Structure
MDALIMAGGKGTRLNLNVEKPLLKILDKPMIDYIIGELLKSKINKIYIATSKHTPKTKKY
CCEEEEECCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHCEEEEEECCCCCHHHHH
LINKYNNNNKVIIVDTEGTDYIHDLNQCISYFSKPFMMLSCDIPSIKSKLINNIINYYNN
HHHEECCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHC
INNKKEALCVVIEKNNYLGNPTLILNEYDKIPAGINILSPKQGCQTEEIYVVNEPLININ
CCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCEEECCCCCCCCCEEEEECCCEEEEE
TLKDKEIVENIFGGEYKKLNKK
CCCHHHHHHHHHCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]