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The map label for this gene is argB

Identifier: 150400565

GI number: 150400565

Start: 142183

End: 143067

Strand: Direct

Name: argB

Synonym: Maeo_0127

Alternate gene names: 150400565

Gene position: 142183-143067 (Clockwise)

Preceding gene: 150400561

Following gene: 150400566

Centisome position: 9.06

GC content: 33.67

Gene sequence:

>885_bases
ATGGATAACGCATTAAAAGCAGAAGTATTAATTGAATCCCTTCCATATATCTGCAAATTTCAAGACCAGAAAATAGTAAT
TAAATATGGCGGACATGCCATGGTAGATGAAGAGGCTAAAAGCTGGATAGCAAAAGATGTAGTTCTTTTAAGATTTGTAG
GTTTAAATCCTGTTATAATTCACGGAGGCGGTCCTGAAATAAATAAAGCAATGGAAAAGATGGGAAAAGAACCTGAATTC
ATACACGGTTTAAGAGTAACAGATGAAGAAACTCTTGATATTGTTAAAATGGTATTAATTGGTAAAATTAATGGAGACAT
TGTTTCAAAGCTTGGAAAATATGGTGGAAAAGCTGTTGGACTTTCTGGAAAATCTGGACACCTAATATCTGCACGAAAAA
AAATACAATATATAATAAAAGAAGATGAAAAAATAGAGGTAGATTTAGGGAGAGTTGGGGAAGTAGATAGTATAAACACA
GAATTAATTGACATACTACTTGAAAAAAAGTATATTCCAGTAATTTCACCAATTGGCATTGACTCTCAGGCTAATACCTA
CAATTTAAATGCAGATATTGCGGCCGGAGATATTGCGGGGGCAATTAATGCAAAAAAATTAATAATGATAACGGATGTAG
ATGGCGTAATGGACGATATAAATGACCCTTCAACAATTTATAAAAAATTGACAATATCCCAAGTTGGGGAAATGATTGAT
AAGGGCATTATAAGTGGGGGAATGATTCCAAAAATTGAGGCTTGTGTGAATGCACTTAGAAAAGGGGTGGATAGTGTGCA
TATTATCAATGGAAAAATACCGCATTCTGTTCTATTAGAGGTTTTTACAGAGGAAGGAATTGGAACAATGATTACAAGAG
ACTAA

Upstream 100 bases:

>100_bases
TACCTAAAAACACAACAATATATAAAATACAATGCTGAAATATAAAATAATAAAATATCACTTAAAATATAATTAAAAAT
TAATAAATAATGGTGAAATA

Downstream 100 bases:

>100_bases
TTTTTTATTTTTTTATTTTTTTGGGAGCTCCCAATATAAAAATATAAAATCCGCCATAATCTACGATATATTTAAATAAT
TTAAATAAAATTAATATTAA

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MDNALKAEVLIESLPYICKFQDQKIVIKYGGHAMVDEEAKSWIAKDVVLLRFVGLNPVIIHGGGPEINKAMEKMGKEPEF
IHGLRVTDEETLDIVKMVLIGKINGDIVSKLGKYGGKAVGLSGKSGHLISARKKIQYIIKEDEKIEVDLGRVGEVDSINT
ELIDILLEKKYIPVISPIGIDSQANTYNLNADIAAGDIAGAINAKKLIMITDVDGVMDDINDPSTIYKKLTISQVGEMID
KGIISGGMIPKIEACVNALRKGVDSVHIINGKIPHSVLLEVFTEEGIGTMITRD

Sequences:

>Translated_294_residues
MDNALKAEVLIESLPYICKFQDQKIVIKYGGHAMVDEEAKSWIAKDVVLLRFVGLNPVIIHGGGPEINKAMEKMGKEPEF
IHGLRVTDEETLDIVKMVLIGKINGDIVSKLGKYGGKAVGLSGKSGHLISARKKIQYIIKEDEKIEVDLGRVGEVDSINT
ELIDILLEKKYIPVISPIGIDSQANTYNLNADIAAGDIAGAINAKKLIMITDVDGVMDDINDPSTIYKKLTISQVGEMID
KGIISGGMIPKIEACVNALRKGVDSVHIINGKIPHSVLLEVFTEEGIGTMITRD
>Mature_294_residues
MDNALKAEVLIESLPYICKFQDQKIVIKYGGHAMVDEEAKSWIAKDVVLLRFVGLNPVIIHGGGPEINKAMEKMGKEPEF
IHGLRVTDEETLDIVKMVLIGKINGDIVSKLGKYGGKAVGLSGKSGHLISARKKIQYIIKEDEKIEVDLGRVGEVDSINT
ELIDILLEKKYIPVISPIGIDSQANTYNLNADIAAGDIAGAINAKKLIMITDVDGVMDDINDPSTIYKKLTISQVGEMID
KGIISGGMIPKIEACVNALRKGVDSVHIINGKIPHSVLLEVFTEEGIGTMITRD

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=282, Percent_Identity=27.6595744680851, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI145693208, Length=237, Percent_Identity=31.2236286919831, Blast_Score=89, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6320913, Length=292, Percent_Identity=27.3972602739726, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_META3 (A6UT97)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001324331.1
- ProteinModelPortal:   A6UT97
- SMR:   A6UT97
- STRING:   A6UT97
- GeneID:   5327506
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_0127
- eggNOG:   arNOG04941
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- ProtClustDB:   PRK00942
- BioCyc:   MAEO419665:MAEO_0127-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_A
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 31943; Mature: 31943

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: BINDING 85-85 BINDING 188-188

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNALKAEVLIESLPYICKFQDQKIVIKYGGHAMVDEEAKSWIAKDVVLLRFVGLNPVII
CCCHHHHHHHHHHCCCEEEECCCEEEEEECCCEEECHHHHHHHHHHHHHHHEECCCEEEE
HGGGPEINKAMEKMGKEPEFIHGLRVTDEETLDIVKMVLIGKINGDIVSKLGKYGGKAVG
ECCCCHHHHHHHHHCCCCCCEECEECCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEE
LSGKSGHLISARKKIQYIIKEDEKIEVDLGRVGEVDSINTELIDILLEKKYIPVISPIGI
CCCCCCCEEHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEECCCCC
DSQANTYNLNADIAAGDIAGAINAKKLIMITDVDGVMDDINDPSTIYKKLTISQVGEMID
CCCCCEEECCCCEECCCHHCCCCCCEEEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHH
KGIISGGMIPKIEACVNALRKGVDSVHIINGKIPHSVLLEVFTEEGIGTMITRD
HHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure
MDNALKAEVLIESLPYICKFQDQKIVIKYGGHAMVDEEAKSWIAKDVVLLRFVGLNPVII
CCCHHHHHHHHHHCCCEEEECCCEEEEEECCCEEECHHHHHHHHHHHHHHHEECCCEEEE
HGGGPEINKAMEKMGKEPEFIHGLRVTDEETLDIVKMVLIGKINGDIVSKLGKYGGKAVG
ECCCCHHHHHHHHHCCCCCCEECEECCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEE
LSGKSGHLISARKKIQYIIKEDEKIEVDLGRVGEVDSINTELIDILLEKKYIPVISPIGI
CCCCCCCEEHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEECCCCC
DSQANTYNLNADIAAGDIAGAINAKKLIMITDVDGVMDDINDPSTIYKKLTISQVGEMID
CCCCCEEECCCCEECCCHHCCCCCCEEEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHH
KGIISGGMIPKIEACVNALRKGVDSVHIINGKIPHSVLLEVFTEEGIGTMITRD
HHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA